Citation: T. Wurch et Pj. Pauwels, Analytical pharmacology of G protein-coupled receptors by stoichiometric expression of the receptor and G alpha protein subunits, J PHARM TOX, 45(1), 2001, pp. 3-16
Authors:
Robinet, EA
Geurts, M
Maloteaux, JM
Pauwels, PJ
Citation: Ea. Robinet et al., Chronic treatment with certain antipsychotic drugs preserves upregulation of regulator of G-protein signalling 2 mRNA in rat striatum as opposed to c-fos mRNA, NEUROSCI L, 307(1), 2001, pp. 45-48
Authors:
Dupuis, DS
Wurch, T
Tardif, S
Colpaert, FC
Pauwels, PJ
Citation: Ds. Dupuis et al., Modulation of 5-HT1A receptor activation by its interaction with wild-typeand mutant G(alpha i3) proteins, NEUROPHARM, 40(1), 2001, pp. 36-47
Authors:
Pauwels, PJ
Wurch, T
Tardif, S
Finana, F
Colpaert, FC
Citation: Pj. Pauwels et al., Analysis of ligand activation of alpha(2)-adrenoceptor subtypes under conditions of equal G alpha protein stoichiometry, N-S ARCH PH, 363(5), 2001, pp. 526-536
Citation: T. Wurch et al., Reciprocal modulation of alpha(2A)-adrenoceptor and G(alpha o) protein states as determined by carboxy-terminal mutagenesis of a G(alpha o) protein, MOLEC PHARM, 60(4), 2001, pp. 666-673
Citation: T. Wurch et al., Agonist-independent and -dependent oligomerization of doparnine D-2 receptors by fusion to fluorescent proteins, FEBS LETTER, 507(1), 2001, pp. 109-113
Authors:
Koek, W
Vacher, B
Cosi, C
Assie, MB
Patoiseau, JF
Pauwels, PJ
Colpaert, FC
Citation: W. Koek et al., 5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential, EUR J PHARM, 420(2-3), 2001, pp. 103-112
Authors:
Pauwels, PJ
Tardif, S
Wurch, T
Colpaert, FC
Citation: Pj. Pauwels et al., Real-time analysis of dopamine: antagonist interactions at recombinant human D-2long receptor upon modulation of its activation state, BR J PHARM, 134(1), 2001, pp. 88-97
Authors:
Bhalla, P
Sharma, HS
Ma, XQ
Wurch, T
Pauwels, PJ
Saxena, PR
Citation: P. Bhalla et al., Molecular cloning, pharmacological properties and tissue distribution of the porcine 5-HT1B receptor, BR J PHARM, 133(6), 2001, pp. 891-901
Citation: Pj. Pauwels et al., Differential signalling of both wild-type and Thr(343) Arg dopamine D-2short receptor by partial agonists in a G-protein-dependent manner, BIOCH PHARM, 62(6), 2001, pp. 723-732
Authors:
Pauwels, PJ
Tardif, S
Colpaert, FC
Wurch, T
Citation: Pj. Pauwels et al., Modulation of ligand responses by coupling of alpha(2A)-adrenoceptors to diverse G(alpha)-proteins, BIOCH PHARM, 61(9), 2001, pp. 1079-1092
Citation: T. Wurch et al., Optimisation of overlap extension PCR-based mutagenesis of a GC-rich DNA template: application to the human alpha(2C)-adrenoceptor cDNA, BIOTECH LET, 22(20), 2000, pp. 1603-1609
Citation: Pj. Pauwels et Fc. Colpaert, Heterogeneous ligand-mediated Ca++ responses at wt and mutant alpha(2A)-adrenoceptors suggest multiple ligand activation binding sites at the alpha(2A)-adrenoceptor, NEUROPHARM, 39(11), 2000, pp. 2101-2111
Authors:
Pauwels, PJ
Finana, F
Tardif, S
Colpaert, FC
Wurch, T
Citation: Pj. Pauwels et al., Agonist efficacy at the alpha(2A)-adrenoceptor : G(alpha 15) fusion protein: an analysis based on Ca2+ responses, N-S ARCH PH, 361(6), 2000, pp. 672-679
Authors:
Pauwels, PJ
Tardif, S
Wurch, T
Colpaert, FC
Citation: Pj. Pauwels et al., Facilitation of constitutive alpha(2A)-adrenoceptor activity by both single amino acid mutation (Thr(373)Lys) and G(alpha o) protein coexpression: Evidence for inverse agonism, J PHARM EXP, 292(2), 2000, pp. 654-663
Citation: T. Wurch et Pj. Pauwels, Coupling of canine serotonin 5-HT1B and 5-HT1D receptor subtypes to the formation of inositol phosphates by dual interactions with endogenous G(i/o) and recombinant G(alpha 15) proteins, J NEUROCHEM, 75(3), 2000, pp. 1180-1189
Authors:
Pauwels, PJ
Tardif, S
Finana, F
Wurch, T
Colpaert, FC
Citation: Pj. Pauwels et al., Ligand-receptor interactions as controlled by wild-type and mutant Thr(370)Lys alpha(2B)-adrenoceptor-G(alpha 15) fusion proteins, J NEUROCHEM, 74(1), 2000, pp. 375-384
Authors:
Mayer, P
Brunel, P
Chaplain, C
Piedecoq, C
Calmel, F
Schambel, P
Chopin, P
Wurch, T
Pauwels, PJ
Marien, M
Vidaluc, JL
Imbert, T
Citation: P. Mayer et al., New substituted 1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl derivatives with alpha(2)-adrenoceptor antagonist activity, J MED CHEM, 43(20), 2000, pp. 3653-3664
Authors:
Le Grand, B
Panissie, A
Perez, M
Pauwels, PJ
John, GW
Citation: B. Le Grand et al., Zolmitriptan stimulates a Ca2+-dependent K+ current in C6 glioma cells stably expressing recombinant human 5-HT1B receptors, EUR J PHARM, 397(2-3), 2000, pp. 297-302
Citation: Pj. Pauwels et Fc. Colpaert, Partial to complete antagonism by putative antagonists at the wild-type alpha(2C)-adrenoceptor based on kinetic analyses of agonist : antagonist interactions, BR J PHARM, 131(7), 2000, pp. 1385-1390
Authors:
Bhalla, P
Sharma, HS
Wurch, T
Pauwels, PJ
Saxena, PR
Citation: P. Bhalla et al., Molecular cloning, sequence analysis and pharmacological properties of theporcine 5-HT1D receptor, BR J PHARM, 131(5), 2000, pp. 949-957