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Results: 1-25/29
Authors:
Nyman, M
Raunio, H
Taavitsainen, P
Pelkonen, O
Citation: M. Nyman et al., Characterization of xenobiotic-metabolizing cytochrome P450 (CYP) forms inringed and grey seals from the Baltic Sea and reference sites, COMP BIOC C, 128(1), 2001, pp. 99-112
Authors:
Raunio, H
Rautio, A
Gullsten, H
Pelkonen, O
Citation: H. Raunio et al., Polymorphisms of CYP2A6 and its practical consequences, BR J CL PH, 52(4), 2001, pp. 357-363
Authors:
Iscan, M
Klaavuniemi, T
Coban, T
Kapucuoglu, N
Pelkonen, O
Raunio, H
Citation: M. Iscan et al., The expression of cytochrome P450 enzymes in human breast tumours and normal breast tissue, BREAST CANC, 70(1), 2001, pp. 47-54
Authors:
Hyyti, OM
Nyman, M
Willis, ML
Raunio, H
Pelkonen, O
Citation: Om. Hyyti et al., Distribution of cytochrome P4501A (CYP1A) in the tissues of Baltic ringed and grey seals, MAR ENV RES, 51(5), 2001, pp. 465-485
Authors:
Andersson, TB
Sjoberg, H
Hoffmann, KJ
Boobis, AR
Watts, P
Edwards, RJ
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Goldfarb, PS
Lewis, DFV
Corcos, L
Guillouzo, A
Taavitsainen, P
Pelkonen, O
Citation: Tb. Andersson et al., An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant, DRUG META D, 29(5), 2001, pp. 712-720
Authors:
Taavitsainen, P
Juvonen, R
Pelkonen, O
Citation: P. Taavitsainen et al., In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene, DRUG META D, 29(3), 2001, pp. 217-222
Authors:
Hidestrand, M
Oscarson, M
Salonen, JS
Nyman, L
Pelkonen, O
Turpeinen, M
Ingelman-Sundberg, M
Citation: M. Hidestrand et al., CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with recombinant enzymes, DRUG META D, 29(11), 2001, pp. 1480-1484
Authors:
Pelkonen, O
Myllynen, P
Taavitsainen, P
Boobis, AR
Watts, P
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Guillouzo, A
Corcos, L
Goldfarb, PS
Lewis, DFV
Citation: O. Pelkonen et al., Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems, XENOBIOTICA, 31(6), 2001, pp. 321-343
Authors:
Hakkola, J
Raunio, H
Purkunen, R
Saarikoski, S
Vahakangas, K
Pelkonen, O
Edwards, RJ
Boobis, AR
Pasanen, M
Citation: J. Hakkola et al., Cytochrome P450 3A expression in the human fetal liver: Evidence that CYP3A5 is expressed in only a limited number of fetal livers, BIOL NEONAT, 80(3), 2001, pp. 193-201
Authors:
Viitala, P
Posti, K
Lindfors, A
Pelkonen, O
Raunio, H
Citation: P. Viitala et al., cAMP mediated upregulation of CYP2A5 in mouse hepatocytes, BIOC BIOP R, 280(3), 2001, pp. 761-767
Authors:
Pelkonen, O
Boobis, AR
Kremers, P
Ingelman-Sundberg, M
Rane, A
Citation: O. Pelkonen et al., Interindividual variation of P450 enzymes in vitro and its causes, INTERINDIVIDUAL VARIABILITY IN HUMAN DRUG METABOLISM, 2001, pp. 269-332
Authors:
Nyman, M
Raunio, H
Pelkonen, O
Citation: M. Nyman et al., Expression and inducibility of members in the cytochrome P4501 (CYP1) family in ringed and grey seals from polluted and less polluted waters, ENV TOX PH, 8(4), 2000, pp. 217-225
Authors:
Hukkanen, J
Lassila, A
Paivarinta, K
Valanne, S
Sarpo, S
Hakkola, J
Pelkonen, O
Raunio, H
Citation: J. Hukkanen et al., Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line, AM J RESP C, 22(3), 2000, pp. 360-366
Authors:
Karjalainen, A
Kalapudas, A
Sodervall, M
Pelkonen, O
Lammintausta, R
Citation: A. Karjalainen et al., Synthesis of new potent and selective aromatase inhibitors based on long-chained diarylalkylimidazole and diarylalkyltriazole molecule skeletons, EUR J PH SC, 11(2), 2000, pp. 109-131
Authors:
Taavitsainen, P
Anttila, M
Nyman, L
Karnani, H
Salonen, JS
Pelkonen, O
Citation: P. Taavitsainen et al., Selegiline metabolism and cytochrome P450 enzymes: In vitro study in humanliver microsomes, PHARM TOX, 86(5), 2000, pp. 215-221
Authors:
Dybing, E
Pelkonen, O
Citation: E. Dybing et O. Pelkonen, Letter from the MiniReview editors, PHARM TOX, 86(3), 2000, pp. 101-101
Authors:
Pelkonen, O
Rautio, A
Raunio, H
Pasanen, M
Citation: O. Pelkonen et al., CYP2A6: a human coumarin 7-hydroxylase, TOXICOLOGY, 144(1-3), 2000, pp. 139-147
Authors:
Paakki, P
Kirkinen, P
Helin, HL
Pelkonen, O
Raunio, H
Pasanen, M
Citation: P. Paakki et al., Antepartum glucocorticoid therapy suppresses human placental xenobiotic and steroid metabolizing enzymes, PLACENTA, 21(2-3), 2000, pp. 241-246
Authors:
Donato, MT
Viitala, P
Rodriguez-Antona, C
Lindfors, A
Castell, JV
Raunio, H
Gomez-Lechon, MJ
Pelkonen, O
Citation: Mt. Donato et al., CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers, DRUG META D, 28(11), 2000, pp. 1321-1326
Authors:
Renwick, AB
Watts, PS
Edwards, RJ
Barton, PT
Guyonnet, I
Price, RJ
Tredger, JM
Pelkonen, O
Boobis, AR
Lake, BG
Citation: Ab. Renwick et al., Differential maintenance of cytochrome P450 enzymes in cultured precision-cut human liver slices, DRUG META D, 28(10), 2000, pp. 1202-1209
Authors:
Taavitsainen, P
Kiukaanniemi, K
Pelkonen, O
Citation: P. Taavitsainen et al., In vitro inhibition screening of human hepatic P-450 enzymes by five angiotensin-II receptor antagonists, EUR J CL PH, 56(2), 2000, pp. 135-140
Authors:
Raunio, H
Hakkola, J
Hukkanen, J
Lassila, A
Paivarinta, K
Pelkonen, O
Anttila, S
Piipari, R
Boobis, A
Edwards, RJ
Citation: H. Raunio et al., Expression of xenobiotic-metabolizing CYPs in human pulmonary tissue, EXP TOX PAT, 51(4-5), 1999, pp. 412-417
Authors:
Brittelli, A
De Santi, C
Raunio, H
Pelkonen, O
Rossi, G
Pacifici, GM
Citation: A. Brittelli et al., Interethnic and interindividual variabilities of platelet sulfotransferases activity in Italians and Finns, EUR J CL PH, 55(9), 1999, pp. 691-695
Authors:
Oscarson, M
McLellan, RA
Gullsten, H
Agundez, JAG
Benitez, J
Rautio, A
Raunio, H
Pelkonen, O
Ingelman-Sundberg, M
Citation: M. Oscarson et al., Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism, FEBS LETTER, 460(2), 1999, pp. 321-327
Authors:
Oscarson, M
McLellan, RA
Gullsten, H
Yue, QY
Lang, MA
Bernal, ML
Sinues, B
Hirvonen, A
Raunio, H
Pelkonen, O
Ingelman-Sundberg, M
Citation: M. Oscarson et al., Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population, FEBS LETTER, 448(1), 1999, pp. 105-110