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Results: 1-20 |
Results: 20
2 '-C-branched ribonucleosides. 2. Synthesis of 2 '-C-beta-trifluoromethylpyrimidine ribonucleosides
Authors: Li, NS Tang, XQ Piccirilli, JA
Citation: Ns. Li et al., 2 '-C-branched ribonucleosides. 2. Synthesis of 2 '-C-beta-trifluoromethylpyrimidine ribonucleosides, ORG LETT, 3(7), 2001, pp. 1025-1028
Crystal structure of 3 ',5 '-di-O-acetyl-2 '-C-alpha-acetyloxymethyl-2,2 '-anhydro-1-(beta-D-arabinofuranosyl)uracil, C16H18N2O9
Authors: Dai, Q Piccirilli, JA Zheng, C Li, SJ
Citation: Q. Dai et al., Crystal structure of 3 ',5 '-di-O-acetyl-2 '-C-alpha-acetyloxymethyl-2,2 '-anhydro-1-(beta-D-arabinofuranosyl)uracil, C16H18N2O9, Z KRIST-NEW, 216(3), 2001, pp. 343-346
Metal ion coordination by the AGC triad in domain 5 contributes to group II intron catalysis
Authors: Gordon, PM Piccirilli, JA
Citation: Pm. Gordon et Ja. Piccirilli, Metal ion coordination by the AGC triad in domain 5 contributes to group II intron catalysis, NAT ST BIOL, 8(10), 2001, pp. 893-898
The Tetrahymena ribozyme cleaves a 5 '-methylene phosphonate monoester similar to 10(2)-fold faster than a normal phosphate diester: Implications forenzyme catalysis of phosphoryl transfer reactions
Authors: Liao, XM Anjaneyulu, PSR Curley, JF Hsu, M Boehringer, M Caruthers, MH Piccirilli, JA
Citation: Xm. Liao et al., The Tetrahymena ribozyme cleaves a 5 '-methylene phosphonate monoester similar to 10(2)-fold faster than a normal phosphate diester: Implications forenzyme catalysis of phosphoryl transfer reactions, BIOCHEM, 40(37), 2001, pp. 10911-10926
Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2 '-modified nucleosides (vol 39, pg 6410, 2000)
Authors: Earnshaw, DJ Hamm, ML Piccirilli, JA Karpeisky, A Beigelman, L Ross, BS Manoharan, M Gait, MJ
Citation: Dj. Earnshaw et al., Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2 '-modified nucleosides (vol 39, pg 6410, 2000), BIOCHEM, 40(24), 2001, pp. 7350-7350
Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction
Authors: Shan, S Kravchuk, AV Piccirilli, JA Herschlag, D
Citation: S. Shan et al., Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction, BIOCHEM, 40(17), 2001, pp. 5161-5171
Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: Extending the parallels between the spliceosome and group II introns
Authors: Gordon, PM Sontheimer, EJ Piccirilli, JA
Citation: Pm. Gordon et al., Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: Extending the parallels between the spliceosome and group II introns, RNA, 6(2), 2000, pp. 199-205
The role of the cleavage site 2 '-hydroxyl in the Tetrahymena group I ribozyme reaction
Authors: Yoshida, A Shan, S Herschlag, D Piccirilli, JA
Citation: A. Yoshida et al., The role of the cleavage site 2 '-hydroxyl in the Tetrahymena group I ribozyme reaction, CHEM BIOL, 7(2), 2000, pp. 85-96
Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3 '-S-phosphorothiolate internucleotide linkage
Authors: Warnecke, JM Sontheimer, EJ Piccirilli, JA Hartmann, RK
Citation: Jm. Warnecke et al., Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3 '-S-phosphorothiolate internucleotide linkage, NUCL ACID R, 28(3), 2000, pp. 720-727
Kinetic characterization of the second step of group II intron splicing: Role of metal ions and the cleavage site 2 '-OH in catalysis
Authors: Gordon, PM Sontheimer, EJ Piccirilli, JA
Citation: Pm. Gordon et al., Kinetic characterization of the second step of group II intron splicing: Role of metal ions and the cleavage site 2 '-OH in catalysis, BIOCHEM, 39(42), 2000, pp. 12939-12952
Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2 '-modified nucleosides
Authors: Earnshaw, DJ Hamm, MLH Piccirilli, JA Karpeisky, A Beigelman, L Ross, BS Manoharan, M Gait, MJ
Citation: Dj. Earnshaw et al., Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2 '-modified nucleosides, BIOCHEM, 39(21), 2000, pp. 6410-6421
Unconventional origin of metal ion rescue in the hammerhead ribozyme reaction: Mn2+-assisted redox conversion of 2 '-mercaptocytidine to cytidine
Authors: Hamm, ML Nikolic, D van Breemen, RB Piccirilli, JA
Citation: Ml. Hamm et al., Unconventional origin of metal ion rescue in the hammerhead ribozyme reaction: Mn2+-assisted redox conversion of 2 '-mercaptocytidine to cytidine, J AM CHEM S, 122(49), 2000, pp. 12069-12078
The hammerhead ribozyme catalyzes the deglycosylation of 2 '-mercaptocytidine
Authors: Hamm, ML Schwans, JP Piccirilli, JA
Citation: Ml. Hamm et al., The hammerhead ribozyme catalyzes the deglycosylation of 2 '-mercaptocytidine, J AM CHEM S, 122(17), 2000, pp. 4223-4224
Do enzymes obey the Baldwin rules? A mechanistic imperative in enzymatic cyclization reactions
Authors: Piccirilli, JA
Citation: Ja. Piccirilli, Do enzymes obey the Baldwin rules? A mechanistic imperative in enzymatic cyclization reactions, CHEM BIOL, 6(3), 1999, pp. R59-R64
A new metal ion interaction in the Tetrahymena ribozyme reaction revealed by double sulfur substitution
Authors: Yoshida, A Sun, SG Piccirilli, JA
Citation: A. Yoshida et al., A new metal ion interaction in the Tetrahymena ribozyme reaction revealed by double sulfur substitution, NAT ST BIOL, 6(4), 1999, pp. 318-321
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
Authors: Sontheimer, EJ Gordon, PM Piccirilli, JA
Citation: Ej. Sontheimer et al., Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome, GENE DEV, 13(13), 1999, pp. 1729-1741
Three metal ions at the active site of the Tetrahymena group I ribozyme
Authors: Shan, SO Yoshida, A Sun, SG Piccirilli, JA Herschlag, D
Citation: So. Shan et al., Three metal ions at the active site of the Tetrahymena group I ribozyme, P NAS US, 96(22), 1999, pp. 12299-12304
2 '-C-branched ribonucleosides: Synthesis of the phosphoramidite derivatives of 2 '-C-beta-methylcytidine and their incorporation into oligonucleotides
Authors: Tang, XQ Liao, XM Piccirilli, JA
Citation: Xq. Tang et al., 2 '-C-branched ribonucleosides: Synthesis of the phosphoramidite derivatives of 2 '-C-beta-methylcytidine and their incorporation into oligonucleotides, J ORG CHEM, 64(3), 1999, pp. 747-754
Synthesis and characterization of oligonucleotides containing 2 '-S,3 '-O-cyclic phosphorothiolate termini
Authors: Hamm, ML Piccirilli, JA
Citation: Ml. Hamm et Ja. Piccirilli, Synthesis and characterization of oligonucleotides containing 2 '-S,3 '-O-cyclic phosphorothiolate termini, J ORG CHEM, 64(15), 1999, pp. 5700-5704
Structures of normal single-stranded DNA and deoxyribo-3 '-S-phosphorothiolates bound to the 3 '-5 ' exonucleolytic active site of DNA polymerase I from Escherichia coli
Authors: Brautigam, CA Sun, S Piccirilli, JA Steitz, TA
Citation: Ca. Brautigam et al., Structures of normal single-stranded DNA and deoxyribo-3 '-S-phosphorothiolates bound to the 3 '-5 ' exonucleolytic active site of DNA polymerase I from Escherichia coli, BIOCHEM, 38(2), 1999, pp. 696-704
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