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Results: 1-14 |
Results: 14
A unique PPAR gamma ligand with potent insulin-sensitizing yet weak adipogenic activity
Authors: Rocchi, S Picard, F Vamecq, J Gelman, L Potier, N Zeyer, D Dubuquoy, L Bac, P Champy, MF Plunket, KD Leesnitzer, LM Blanchard, SG Desreumaux, P Moras, D Renaud, JP Auwerx, J
Citation: S. Rocchi et al., A unique PPAR gamma ligand with potent insulin-sensitizing yet weak adipogenic activity, MOL CELL, 8(4), 2001, pp. 737-747
Synthesis and biological activity of L-tyrosine-based PPAR gamma agonists with reduced molecular weight
Authors: Liu, KG Lambert, MH Ayscue, AH Henke, BR Leesnitzer, LM Oliver, WR Plunket, KD Xu, HE Sternbach, DD Willson, TM
Citation: Kg. Liu et al., Synthesis and biological activity of L-tyrosine-based PPAR gamma agonists with reduced molecular weight, BIOORG MED, 11(24), 2001, pp. 3111-3113
Identification of a series of PPAR-gamma/delta dual agonists via solid-phase parallel synthesis
Authors: Liu, KG Lambert, MH Leesnitzer, LM Oliver, W Ott, RJ Plunket, KD Stuart, LW Brown, PJ Willson, TM Sternbach, DD
Citation: Kg. Liu et al., Identification of a series of PPAR-gamma/delta dual agonists via solid-phase parallel synthesis, BIOORG MED, 11(22), 2001, pp. 2959-2962
Identification of a series of oxadiazole-substituted alpha-isopropoxy phenylpropanoic acids with activity on PPAR alpha, PPAR-gamma, and PPAR delta
Authors: Liu, KG Smith, JS Ayscue, AH Henke, BR Lambert, MH Leesnitzer, LM Plunket, KD Willson, TM Sternbach, DD
Citation: Kg. Liu et al., Identification of a series of oxadiazole-substituted alpha-isopropoxy phenylpropanoic acids with activity on PPAR alpha, PPAR-gamma, and PPAR delta, BIOORG MED, 11(17), 2001, pp. 2385-2388
A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport
Authors: Oliver, WR Shenk, JL Snaith, MR Russell, CS Plunket, KD Bodkin, NL Lewis, MC Winegar, DA Sznaidman, ML Lambert, MH Xu, HE Sternbach, DD Kliewer, SA Hansen, BC Willson, TM
Citation: Wr. Oliver et al., A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport, P NAS US, 98(9), 2001, pp. 5306-5311
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
Authors: Xu, HE Lambert, MH Montana, VG Plunket, KD Moore, LB Collins, JB Oplinger, JA Kliewer, SA Gampe, RT McKee, DD Moore, JT Willson, TM
Citation: He. Xu et al., Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors, P NAS US, 98(24), 2001, pp. 13919-13924
Effects of fenofibrate on lipid parameters in obese rhesus monkeys
Authors: Winegar, DA Brown, PJ Wilkison, WO Lewis, MC Ott, RJ Tong, WQ Brown, HR Lehmann, JM Kliewer, SA Plunket, KD Way, JM Bodkin, NL Hansen, BC
Citation: Da. Winegar et al., Effects of fenofibrate on lipid parameters in obese rhesus monkeys, J LIPID RES, 42(10), 2001, pp. 1543-1551
A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma
Authors: Wang, YP Porter, WW Suh, NJ Honda, T Gribble, GW Leesnitzer, LM Plunket, KD Mangelsdorf, DJ Blanchard, SG Willson, TM Sporn, MB
Citation: Yp. Wang et al., A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma, MOL ENDOCR, 14(10), 2000, pp. 1550-1556
Identification of a chemical tool for the orphan nuclear receptor FXR
Authors: Maloney, PR Parks, DJ Haffner, CD Fivush, AM Chandra, G Plunket, KD Creech, KL Moore, LB Wilson, JG Lewis, MC Jones, SA Willson, TM
Citation: Pr. Maloney et al., Identification of a chemical tool for the orphan nuclear receptor FXR, J MED CHEM, 43(16), 2000, pp. 2971-2974
Synthesis and biological activity of a novel series of indole-derived PPARgamma agonists
Authors: Henke, BR Adkison, KK Blanchard, SG Leesnitzer, LM Mook, RA Plunket, KD Ray, JA Roberson, C Unwalla, R Willson, TM
Citation: Br. Henke et al., Synthesis and biological activity of a novel series of indole-derived PPARgamma agonists, BIOORG MED, 9(23), 1999, pp. 3329-3334
A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPAR alpha agonist with potent lipid-lowering activity
Authors: Brown, PJ Winegar, DA Plunket, KD Moore, LB Lewis, MC Wilson, JG Sundseth, SS Koble, CS Wu, ZD Chapman, JM Lehmann, JM Kliewer, SA Willson, TM
Citation: Pj. Brown et al., A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPAR alpha agonist with potent lipid-lowering activity, J MED CHEM, 42(19), 1999, pp. 3785-3788
A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat
Authors: Brown, KK Henke, BR Blanchard, SG Cobb, JE Mook, R Kaldor, I Kliewer, SA Lehmann, JM Lenhard, JM Harrington, WW Novak, PJ Faison, W Binz, JG Hashim, MA Oliver, WO Brown, HR Parks, DJ Plunket, KD Tong, WQ Menius, JA Adkison, K Noble, SA Willson, TM
Citation: Kk. Brown et al., A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat, DIABETES, 48(7), 1999, pp. 1415-1424
N-(2-benzoylphenyl)-L-tyrosine PPAR gamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents
Authors: Henke, BR Blanchard, SG Brackeen, MF Brown, KK Cobb, JE Collins, JL Harrington, WW Hashim, MA Hull-Ryde, EA Kaldor, I Kliewer, SA Lake, DH Leesnitzer, LM Lehmann, JM Lenhard, JM Orband-Miller, LA Miller, JF Mook, RA Noble, SA Oliver, W Parks, DJ Plunket, KD Szewczyk, JR Willson, TM
Citation: Br. Henke et al., N-(2-benzoylphenyl)-L-tyrosine PPAR gamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents, J MED CHEM, 41(25), 1998, pp. 5020-5036
N-(2-benzoylphenyl)-L-tyrosine PPAR gamma agonists. 3. Structure-activity relationship and optimization of the N-aryl substituent
Authors: Cobb, JE Blanchard, SG Boswell, EG Brown, KK Charifson, PS Cooper, JP Collins, JL Dezube, M Henke, BR Hull-Ryde, EA Lake, DH Lenhard, JM Oliver, W Oplinger, J Pentti, M Parks, DJ Plunket, KD Tong, WQ
Citation: Je. Cobb et al., N-(2-benzoylphenyl)-L-tyrosine PPAR gamma agonists. 3. Structure-activity relationship and optimization of the N-aryl substituent, J MED CHEM, 41(25), 1998, pp. 5055-5069
Risultati: 1-14 |