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Results: 1-24 |
Results: 24
Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKB alpha
Authors: Tuttle, RL Gill, NS Pugh, W Lee, JP Koeberlein, B Furth, EE Polonsky, KS Naji, A Birnbaum, MJ
Citation: Rl. Tuttle et al., Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKB alpha, NAT MED, 7(10), 2001, pp. 1133-1137
GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve
Authors: Brandt, A Katschinski, M Arnold, R Polonsky, KS Goke, B Byrne, MM
Citation: A. Brandt et al., GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve, AM J P-ENDO, 281(2), 2001, pp. E242-E247
Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models
Authors: Toffolo, G Breda, E Cavaghan, MK Ehrmann, DA Polonsky, KS Cobelli, C
Citation: G. Toffolo et al., Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models, AM J P-ENDO, 280(1), 2001, pp. E2-E10
The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes
Authors: Polonsky, KS Semenkovich, CF
Citation: Ks. Polonsky et Cf. Semenkovich, The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes, CELL, 105(6), 2001, pp. 705-707
Mechanisms of disease: Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.
Authors: Fajans, SS Bell, GI Polonsky, KS
Citation: Ss. Fajans et al., Mechanisms of disease: Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young., N ENG J MED, 345(13), 2001, pp. 971-980
Diabetes mellitus and genetically programmed defects in beta-cell function
Authors: Bell, GI Polonsky, KS
Citation: Gi. Bell et Ks. Polonsky, Diabetes mellitus and genetically programmed defects in beta-cell function, NATURE, 414(6865), 2001, pp. 788-791
Calpains play a role in insulin secretion and action
Authors: Sreenan, SK Zhou, YP Otani, K Hansen, PA Currie, KPM Pan, CY Lee, JP Ostrega, DM Pugh, W Horikawa, Y Cox, NJ Hanis, CL Burant, CF Fox, AP Bell, GI Polonsky, KS
Citation: Sk. Sreenan et al., Calpains play a role in insulin secretion and action, DIABETES, 50(9), 2001, pp. 2013-2020
Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes
Authors: Gautier, JF Wilson, C Weyer, C Mott, D Knowler, WC Cavaghan, M Polonsky, KS Bogardus, C Pratley, RE
Citation: Jf. Gautier et al., Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes, DIABETES, 50(8), 2001, pp. 1828-1833
Loss of HNF-1 alpha function in mice leads to abnormal expression of genesinvolved in pancreatic islet development and metabolism
Authors: Shih, DQ Screenan, S Munoz, KN Philipson, L Pontoglio, M Yaniv, M Polonsky, KS Stoffel, M
Citation: Dq. Shih et al., Loss of HNF-1 alpha function in mice leads to abnormal expression of genesinvolved in pancreatic islet development and metabolism, DIABETES, 50(11), 2001, pp. 2472-2480
Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity
Authors: Breda, E Cavaghan, MK Toffolo, G Polonsky, KS Cobelli, C
Citation: E. Breda et al., Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity, DIABETES, 50(1), 2001, pp. 150-158
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
Authors: Horikawa, Y Oda, N Cox, NJ Li, XQ Orho-Melander, M Hara, M Hinokio, Y Lindner, TH Mashima, H Schwarz, PEH del Bosque-Plata, L Horikawa, Y Oda, Y Yoshiuchi, I Colilla, S Polonsky, KS Wei, S Concannon, P Iwasaki, N Schulze, T Baier, LJ Bogardus, C Groop, L Boerwinkle, E Hanis, CL Bell, GI
Citation: Y. Horikawa et al., Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus, NAT GENET, 26(2), 2000, pp. 163-175
Dynamics of insulin secretion in obesity and diabetes
Authors: Polonsky, KS
Citation: Ks. Polonsky, Dynamics of insulin secretion in obesity and diabetes, INT J OBES, 24, 2000, pp. S29-S31
Roles of insulin resistance and obesity in regulation of plasma insulin concentrations
Authors: Jones, CNO Abbasi, F Carantoni, M Polonsky, KS Reaven, GM
Citation: Cno. Jones et al., Roles of insulin resistance and obesity in regulation of plasma insulin concentrations, AM J P-ENDO, 278(3), 2000, pp. E501-E508
Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion
Authors: Zhou, YP Pena, JC Roe, MW Mittal, A Levisetti, M Baldwin, AC Pugh, W Ostrega, D Ahmed, N Bindokas, VP Philipson, LJ Hanahan, D Thompson, CB Polonsky, KS
Citation: Yp. Zhou et al., Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion, AM J P-ENDO, 278(2), 2000, pp. E340-E351
The Diabetes Prevention Program - Baseline characteristics of the randomized cohort
Authors: Bray, GA Culbert, IW Champagne, CM Dawson, L Eberhardt, B Greenway, FL Guillory, FG Hebert, AA Jeffirs, ML Kennedy, BM Lovejoy, JC Melancon, LE Morris, LH Reed, L Perault, J Ryan, DH Sanford, DA Smith, KG Smith, LL St Amant, JA Tucker, E Tulley, RT Vicknair, PC Williamson, D Zachwieja, JJ Tobian, JA Matulik, MJ Clarke, B Collins, DA Czech, KB DeSandre, C Ehrmann, DA Geiger, G Harding-Clay, B Hilbrich, RM McNabb, WL Polonsky, KS Semenske, AR Stepp, KA Watson, PG Mendoza, JT Smith, KA Goldstein, BJ Lark, C Liberoni, R Murphy, L Pepe, C Spandorfer, JM Goldberg, RB Rowe, P Calles, J Casanova, P Donahue, RP Florez, HJ Giannella, A McLymont, V Mendez, J O'Hara, P Ojito, J Prineas, R Haffner, SM Montez, MG Miettinen, H Mobley, CM Mykkanen, LA Rozek, MM Hamman, RF Nash, PV Calonge, BN Hill, JO Hoyer, SR Jortberg, BT Miller-Stone, M Regensteiner, JG Seagle, H Steinke, SC Testaverde, L Van-Dorsten, B Horton, ES Lawton, KE Arky, RA Bryant, M Burke, JP Caballero, E Callaghan, KM Ganda, OP Franklin, T Jackson, SD Jacobsen, AM Kula, LM Kocal, M Malloy, MA Nicosia, M Oldmixon, CF Pan, J Quitingon, M Rubtchinsky, S Seely, EW Schweizer, D Simonson, D Smith, F Solomon, CG Warram, J Kahn, SE Montgomery, BK Fujimoto, WY Knopp, RH Lipkin, EW Marr, M McCann, BS Nguyen, TT Palmer, JP Schwartz, RS Kitabchi, AE Murphy, ME Applegate, WB Bryer-Ash, M Crisler, A Cunningham, G Franklin, AW Frieson, SL Green, DL Imseis, R Kennedy, CL Lambeth, HC Lichtermann, LC Oktaei, H O'Toole, ML Ricks, H Rutledge, LMK Sherman, AR Smith, CM Soberman, JE Williams-Cleaves, BJ Metzger, BE Johnson, MK Behrends, C Cook, ML Fitzgibbon, M Heard, D McPherson, D Molitch, ME Moore, M Pitts, T Roston, S Schinleber, PA Nathan, DM McKitrick, C Abbott, K Anderson, E Bissett, L Cagliero, E Crowell, S Delahanty, L Fritz, S Levina, E Michel, T Norman, D O'Keefe, J Poulos, A Ronan, L Rosal, M Salerno, M Shagensky, C Steiner, B Turgeon, H Young, A Olefsky, JM Carrion-Petersen, ML Barrett-Connor, E Beltran, M Caenepeel-Mills, K Edelman, SV Ford, RO Garcia, J Henry, RR Hill, M Horne, J Leos, D Mudaliar, S Pollard, A Torio-Hurley, J Pi-Sunyer, FX Lee, JE Allison, DB Aronoff, NJ Barreras, IM Crandall, JP Orlando, SJ Parkes, K Rooney, ES Van Wye, GEH Viscovich, KA Marrero, DG Kukman-Kelly, MS Dotson, YF Fineberg, SE Guare, JC Hadden, A Ignaut, JM Jackson, MA Kirkman, MS Porter, BD Prince, MJ Wheeler, ML Ratner, RE Youssef, G Boner, A Bronsord, M Brown, E Cheatham, WW Cola, S Comfort, A Boggs, G Evans, C Levetan, C Kellum, T Nair, AK Passaro, MD Rubin, R Shapiro, S Saad, MF Budgett, M Jinagouda, SD Aziz, A Bernaba, B Bodkin, SL Ciobanu, V Cosenza, C Hagar, JE Khan, A Kumar, D Khawaja, Q Lui, G Marston, AR Mehta, V Sharma, AR Szamos, K Vargas, A Vargas, B Zambrana, N Dagogo-Jack, S Santiago, AS Brendle, JS Fisher, EB Gherardini, DC Heins, JM Marsala, JM Raspberry, CC Santiago, JV Saudek, CD Bradley, VL Brancati, FL Cappelli, S Charleston, JB Rubin, RR Stewart, KJ Sullivan, E Schade, DS Adams, KS Atler, LF Bowling, DA Boyle, PJ Burge, MR Butler, L Canady, JL Chai, L Guillen, M Gutierrez, M Hornbeck, D Johannes, C Katz, P King, C McCalman, R Montoya, DA Rassam, A Senter, W Shamoon, H Brown, JO Adames, J Blanco, E Cox, L Duffy, H Engel, S Friedler, A Harroun, T Howard-Century, CJ Kloiber, S Longchamp, N Pompi, D Walker, EA Wylie-Rosett, J Zonszein, J Wing, RR Kramer, MK Barr, S Clifford, L Culyba, R Frazier, M Gilligan, R Harris, L Harrier, S Henderson, W Jeffries, S Koenning, G Maholic, K Mullen, M Noel, A Orchard, TJ Otto, A Smith, M Stapinski, V Viteri, J Wilson, T Williams, KV Zgibor, J Arakaki, RF Latimer, RW Baker-Ladao, NK Beddow, RM Dias, LM Dupont, DA Fukuhara, LL Mau, MK Odom, SK Perry, RU Tokunaga, JS Knowler, WC Cooeyate, NJ Hoskin, MA Percy, CA Acton, KJ Andre, VL Antone, S Baptisto, NM Barber, R Bennett, PH Benson, MB Bird, EC Broussard, BA Chavez, M Dacawyma, TS Duncan, R Ghahate, JM Glass, M Gohdes, D Grant, G Hanson, RL Horse, E Hughte, G Ingraham, LE Jackson, MC Jay, PA Kaskalla, RS Kessler, D Kobus, KM Morgan, T Nashboo, Y Poirier, S Reidy, M Ridpath, S Roumain, J Rowse, DH Roy, RJ Sangster, S Sewemaenewa, J Wilson, C Yazzie, M Fowler, S Bain, R Bamdad, J Brenneman, T Callaghan, J Edelstein, SL Grimes, KL Jones, S Jones, TL Lachin, JM Mucik, P Orlosky, R Stimpson, CE Suiter, C Temprosa, E Van Aerden, C Eastman, R Garfield, S Andres, R Engelgau, MM Narayan, KMV Williamson, DF Herman, WH Marcovina, SM Aldrich, A Chandler, WL Rautaharju, PM Alexander, T Pemberton, NT Prineas, R Rautaharju, FSR Zhang, Z Mayer-Davis, EJ Martin, M O'Leary, DH Funk, LRC O'Leary, KA Polak, JF Stamm, ER Scherzinger, AL Wing, RR Gillis, BP Kriska, AM Huffmyer, C Venditti, EM Kaplan, RM David, KM Sieber, WJ
Citation: Ga. Bray et al., The Diabetes Prevention Program - Baseline characteristics of the randomized cohort, DIABET CARE, 23(11), 2000, pp. 1619-1629
Glucagon-like peptide-1 stimulates insulin secretion by a Ca2+-independentmechanism in Zucker diabetic fatty rat islets of langerhans
Authors: Sreenan, SK Mittal, AA Dralyuk, F Pugh, WL Polonsky, KS Roe, MW
Citation: Sk. Sreenan et al., Glucagon-like peptide-1 stimulates insulin secretion by a Ca2+-independentmechanism in Zucker diabetic fatty rat islets of langerhans, METABOLISM, 49(12), 2000, pp. 1579-1587
Interactions between insulin resistance and insulin secretion in the development of glucose intolerance
Authors: Cavaghan, MK Ehrmann, DA Polonsky, KS
Citation: Mk. Cavaghan et al., Interactions between insulin resistance and insulin secretion in the development of glucose intolerance, J CLIN INV, 106(3), 2000, pp. 329-333
Twenty-four-hour leptin levels respond to cumulative short-term energy imbalance and predict subsequent intake
Authors: Chin-Chance, C Polonsky, KS Schoeller, DA
Citation: C. Chin-chance et al., Twenty-four-hour leptin levels respond to cumulative short-term energy imbalance and predict subsequent intake, J CLIN END, 85(8), 2000, pp. 2685-2691
Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes
Authors: Hollingdal, M Juhl, CB Pincus, SM Sturis, J Veldhuis, JD Polonsky, KS Porksen, N Schmitz, O
Citation: M. Hollingdal et al., Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes, DIABETES, 49(8), 2000, pp. 1334-1340
Evolution of beta-cell dysfunction in impaired glucose tolerance and diabetes
Authors: Polonsky, KS
Citation: Ks. Polonsky, Evolution of beta-cell dysfunction in impaired glucose tolerance and diabetes, EXP CL E D, 107, 1999, pp. S124-S127
The Diabetes Prevention Program - Design and methods for a clinical trial in the prevention of type 2 diabetes
Authors: Bray, GA Culbert, IW Champagne, CM Dawson, L Eberhardt, B Greenway, FL Guillory, FG Hebert, AA Jeffirs, ML Kennedy, BM Lovejoy, JC Morris, LH Melancon, LE Reed, L Perault, J Ryan, DH Sanford, DA Smith, KG Smith, LL St Amant, JA Tulley, RT Vicknair, PC Williamson, D Zachwieja, JJ Polonsky, KS Matulik, MJ Clarke, B DeSandre, C Ehrmann, DA Hilbrich, RM McNabb, WL Morrone, D Semenske, AR Stepp, KA Tobian, JA Watson, PG Caro, JF Goldstein, BJ Graziani, CM Kunkel, EJ Laine, CA Louis, DZ Smith, KA Spandirfer, J Yuen, EJ Goldberg, RB Rowe, P Calles, J Donahue, RP Florez, HJ Giannella, A O'Hara, P Prineas, R Haffner, SM Montez, MG Miettinen, H Mobley, CM Mykkanen, LA Hamman, RF Nash, PV Calonge, BN Hill, JO Jortberg, BT Regensteiner, JG Reusch, J Schiltz, CM Seagle, H VanDorsten, B Horton, ES Lawton, KE Arky, RA Bryant, M Burke, JP Caballero, E Callaphan, KM Ganda, OP Franklin, T Jackson, SD Jacobsen, AM Kula, LM Kocal, M Malloy, MA Nicosia, M Oldmixon, CF Pan, J Quitingon, M Rubtchinsky, S Seely, EW Schweizer, D Simonson, D Smith, F Solomon, CG Warram, J Kahn, SE Montgomery, BK Berger, M Boyko, EJ Fujimoto, WY Greenbaum, CJ Knopp, RH McCann, BS Lipkin, EW Nguyen, TT Palmer, JP Schwartz, RS Talbot-Lawson, C Wan, D Kitabchi, AE Murphy, ME Applegate, WB Bryer-Ash, M Frieson, SL Imseis, R Kennedy, CL Lambeth, HC Lichtermann, LC Oktaei, H O'Toole, ML Rutledge, LMK Sherman, AR Smith, CM Soberman, JE Williams-Cleaves, BJ Metzger, BE Johnson, MK Fitzgibbon, M Heard, D Johnson, CKH McPherson, D Molitch, ME Moore, M Pitts, T Schinleber, PA Nathan, DM McKitrick, C Abbott, K Anderson, E Cagliero, E Cohen, M Crowell, S Delahanty, L Levina, E Michel, T O'Keefe, J Poulos, A Ronan, L Rosal, M Salerno, M Shagensky, C Steiner, B Young, A Olefsky, JM Carrion-Petersen, ML Barrett-Connor, E Beltran, M Caenepeel, K Edelman, SV Ford, RO Garcia, J Henry, RR Hill, M Horne, J Leos, D Mudaliar, S Pollard, A Torio, J Pi-Sunyer, FX Lee, JE Allison, DB Aronoff, NJ Barreras, IM Crandall, JP Foo, ST Orlando, SJ Parkes, K Rooney, ES Van Wye, GEH Viscovich, KA Prince, MJ Kukman, SM Dotson, YF Fineberg, ES Guare, JC Ignaut, JM Jackson, MA Kirkman, MS Marrero, DG Porter, DB Rowland, ND Wheeler, ML Ratner, RE Youssef, G Bronsord, M Cheatham, WW Boggs, G Evans, C Levatan, C Kellum, T Nair, AK Passaro, MD Saad, MF Khan, A Aziz, A Bernaba, B Budgett, MD Cosenza, C Hagar, JE Isagholian, K Jinagouda, SD Kamdar, VV Kumar, D Khawaja, Q Kelada, BL Lui, G Marston, AR Mehta, V Sharma, AR Szamos, K Vargas, A Vargas, B Zambrana, N Dagogo-Jack, S Santiago, AE Brendle, JS Fisher, EB Gherardini, DC Heins, JM Marsala, JM Raspberry, CC Santiago, JV Stephan, CL Saudek, CD Bradley, VL Brancati, FL Cappelli, S Charleston, JB Rubin, RR Stewart, KJ Sullivan, E Schade, DS Adams, KS Atler, LF Bowling, DA Boyle, PJ Burge, MR Canady, JL Chai, L Dorin, RI Facio, E Guillen, M Gutierrez, M Johannes, C Katz, P King, C McCalman, R Rassam, A Senter, W Waters, D Shamoon, H Brown, JO Cox, L Duffy, H Engel, S Friedler, A Howard-Century, CJ Longchamp, N Pompi, D Walker, EA Wylie-Rosett, J Zonszein, J Wing, RR Kramer, MK Barr, S Clifford, L Culyba, R Frazier, M Harris, L Harrier, S Henderson, W Jeffries, S Koenning, G Maholic, K Mullen, M Noel, A Orchard, T Smith, CF Smith, M Viteri, J Wilson, T Williams, KV Zgibor, J Arakaki, RF Latimer, RW Baker-Ladao, NK Beddow, RM Dias, LM Dupont, DA Fukuhara, LL Mau, MK Odom, SK Perry, RU Tokunaga, JS Knowler, WC Hoskin, MA Andre, VL Acton, KJ Antone, S Baptisto, NM Bennett, PH Bird, EC Dacawyma, TS Hanson, RL Jackson, MC Jay, PA Kobus, KM Roumain, J Rowse, DH Roy, RJ Yazzie, M Cooeyate, NJ Chavez, M Broussard, BA Ghahate, JM Hughte, G Ingraham, LE Kaskalla, RS Kessler, D Nashboo, Y Poirier, S Percy, CA Barber, R Benson, MB Duncan, R Glass, M Gohdes, D Grant, W Horse, E Morgan, T Reidy, M Bain, R Bambad, J Brenneman, T Dunegan, C Edelstein, SL Grimes, KL Jones, S Jones, TL Klepac, H Lachin, JM Mucik, P Orlosky, R Rochon, J Stimpson, CE Van Aerden, C Eastman, R Garfield, S Harris, M Andres, R Engelgau, M Narayan, V Williamson, D Herman, W Chandler, WL Marcovina, SM McMillan, T Rautaharju, PM Rautaharju, FSR Mayer-Davis, EJ O'Leary, DH Funk, LRC O'Leary, KA Scherzinger, AL Stamm, ER Gillis, BP Kriska, AM Huffmyer, C Meier, A Venditti, EM Wing, RR Haffner, SM Ratner, RE Olefsky, JM Santiago, JV Saudek, CD Knowler, WC Montez, MG Fujimoto, WY Hamman, RF Nathan, DM
Citation: Ga. Bray et al., The Diabetes Prevention Program - Design and methods for a clinical trial in the prevention of type 2 diabetes, DIABET CARE, 22(4), 1999, pp. 623-634
Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: Role of enhanced fuel metabolism
Authors: Zhou, YP Cockburn, BN Pugh, W Polonsky, KS
Citation: Yp. Zhou et al., Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: Role of enhanced fuel metabolism, METABOLISM, 48(7), 1999, pp. 857-864
Metabolic effects of short-term elevations of plasma cortisol are more pronounced in the evening than in the morning
Authors: Plat, L Leproult, R L'Hermite-Baleriaux, M Fery, F Mockel, J Polonsky, KS Van Cauter, E
Citation: L. Plat et al., Metabolic effects of short-term elevations of plasma cortisol are more pronounced in the evening than in the morning, J CLIN END, 84(9), 1999, pp. 3082-3092
Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse
Authors: Sreenan, S Pick, AJ Levisetti, M Baldwin, AC Pugh, M Polonsky, KS
Citation: S. Sreenan et al., Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse, DIABETES, 48(5), 1999, pp. 989-996
Risultati: 1-24 |