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Results: 1-25 | 26-48 |
Results: 26-48/48
Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays
Authors: Bonner, GG Davis, P Stropova, D Edsall, S Yamamura, HI Porreca, F Hruby, VJ
Citation: Gg. Bonner et al., Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays, J MED CHEM, 43(4), 2000, pp. 569-580
Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective delta-opioid receptor agonists from 4-[(alpha R)-alpha-(2S,5R)-4-substituted-2,5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers
Authors: Furness, MS Zhang, XY Coop, A Jacobson, AE Rothman, RB Dersch, CM Xu, H Porreca, F Rice, KC
Citation: Ms. Furness et al., Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective delta-opioid receptor agonists from 4-[(alpha R)-alpha-(2S,5R)-4-substituted-2,5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers, J MED CHEM, 43(16), 2000, pp. 3193-3196
Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability
Authors: Bilsky, EJ Egleton, RD Mitchell, SA Palian, MM Davis, P Huber, JD Jones, H Yamamura, HI Janders, J Davis, TP Porreca, F Hruby, VJ Polt, R
Citation: Ej. Bilsky et al., Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability, J MED CHEM, 43(13), 2000, pp. 2586-2590
The role of the G protein gamma(2) subunit in opioid antinociception in mice
Authors: Hosohata, K Logan, JK Varga, E Burkey, TH Vanderah, TW Porreca, F Hruby, VJ Roeske, WR Yamamura, HI
Citation: K. Hosohata et al., The role of the G protein gamma(2) subunit in opioid antinociception in mice, EUR J PHARM, 392(3), 2000, pp. R9-R11
delta-opioid receptor agonists produce antinociception and [S-35]GTP gammaS binding in mu receptor knockout mice
Authors: Hosohata, Y Vanderah, TW Burkey, TH Ossipov, MH Kovelowski, CJ Sora, I Uhl, GR Zhang, XY Rice, KC Roeske, WR Hruby, VJ Yamamura, HI Lai, J Porreca, F
Citation: Y. Hosohata et al., delta-opioid receptor agonists produce antinociception and [S-35]GTP gammaS binding in mu receptor knockout mice, EUR J PHARM, 388(3), 2000, pp. 241-248
Cyclic enkephalin analogs that are hybrids of DPDPE-related peptides and Metenkephalin-Arg-Gly-Leu: prohormone analogs that retain good potency and selectivity for delta opioid receptors
Authors: Bartosz-Bechowski, H Davis, P Slaninova, J Malatynska, E Stropova, D Porreca, F Yamamura, HI Hruby, VJ
Citation: H. Bartosz-bechowski et al., Cyclic enkephalin analogs that are hybrids of DPDPE-related peptides and Metenkephalin-Arg-Gly-Leu: prohormone analogs that retain good potency and selectivity for delta opioid receptors, J PEPT RES, 53(3), 1999, pp. 329-336
Synthesis and biological activities of position one and three transposed analogs of the opioid peptide YKFA
Authors: Burden, JE Davis, P Porreca, F Spatola, AF
Citation: Je. Burden et al., Synthesis and biological activities of position one and three transposed analogs of the opioid peptide YKFA, BIOORG MED, 9(24), 1999, pp. 3441-3446
Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin
Authors: Lipkowski, AW Misicka, A Davis, P Stropova, D Janders, J Lachwa, M Porreca, F Yamamura, HI Hruby, VJ
Citation: Aw. Lipkowski et al., Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin, BIOORG MED, 9(18), 1999, pp. 2763-2766
Lesions of the dorsolateral funiculus block supraspinal opioid delta receptor mediated antinociception in the rat
Authors: Kovelowski, CJ Ossipov, MH Hruby, VJ Porreca, F
Citation: Cj. Kovelowski et al., Lesions of the dorsolateral funiculus block supraspinal opioid delta receptor mediated antinociception in the rat, PAIN, 83(2), 1999, pp. 115-122
Synergistic antiallodynic effects of spinal morphine with ketorolac and selective COX1- and COX2-inhibitors in nerve-injured rats
Authors: Lashbrook, JM Ossipova, MH Hunter, JC Raffa, RB Tallarida, RJ Porreca, F
Citation: Jm. Lashbrook et al., Synergistic antiallodynic effects of spinal morphine with ketorolac and selective COX1- and COX2-inhibitors in nerve-injured rats, PAIN, 82(1), 1999, pp. 65-72
Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats
Authors: Ossipov, MH Bian, D Malan, TP Lai, J Porreca, F
Citation: Mh. Ossipov et al., Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats, PAIN, 79(2-3), 1999, pp. 127-133
A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain (vol 96, pg 7640, 1999)
Authors: Porreca, F Lai, J Bian, D Wegert, S Ossipov, MH Eglen, RM Kassotakis, L Novakovic, S Rabert, DK Sangameswaran, L Hunter, JC
Citation: F. Porreca et al., A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain (vol 96, pg 7640, 1999), P NAS US, 96(18), 1999, pp. 10548-10548
A comparison of the potential role,of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain
Authors: Porreca, F Lai, J Bian, D Wegert, S Ossipov, MH Eglen, RM Kassotakis, L Novakovic, S Rabert, DK Sangameswaran, L Hunter, JC
Citation: F. Porreca et al., A comparison of the potential role,of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain, P NAS US, 96(14), 1999, pp. 7640-7644
High-affinity interaction of (des-tyrosyl) dynorphin A(2-17) with NMDA receptors
Authors: Tang, QB Gandhoke, R Burritt, A Hruby, VJ Porreca, F Lai, J
Citation: Qb. Tang et al., High-affinity interaction of (des-tyrosyl) dynorphin A(2-17) with NMDA receptors, J PHARM EXP, 291(2), 1999, pp. 760-765
Characterization of antiallodynic actions of ALE-0540, a novel nerve growth factor receptor antagonist, in the rat
Authors: Owolabi, JB Rizkalla, G Tehim, A Ross, GM Riopelle, RJ Kamboj, R Ossipov, M Bian, D Wegert, S Porreca, F Lee, DKH
Citation: Jb. Owolabi et al., Characterization of antiallodynic actions of ALE-0540, a novel nerve growth factor receptor antagonist, in the rat, J PHARM EXP, 289(3), 1999, pp. 1271-1276
delta opioid affinity and selectivity of 4-hydroxy-3-methoxyindolomorphinan analogues related to naltrindole
Authors: Coop, A Rothman, RB Dersch, C Partilla, J Porreca, F Davis, P Jacobson, AE Rice, KC
Citation: A. Coop et al., delta opioid affinity and selectivity of 4-hydroxy-3-methoxyindolomorphinan analogues related to naltrindole, J MED CHEM, 42(9), 1999, pp. 1673-1679
Exploring the structure-activity relationships of [1-(4-tert-butyl-3 '-hydroxy)benzhydryl-4-benzylpiperazine] (SL-3111), a high-affinity and selective delta-opioid receptor nonpeptide agonist ligand
Authors: Alfaro-Lopez, J Okayama, T Hosohata, K Davis, P Porreca, F Yamamura, HI Hruby, VJ
Citation: J. Alfaro-lopez et al., Exploring the structure-activity relationships of [1-(4-tert-butyl-3 '-hydroxy)benzhydryl-4-benzylpiperazine] (SL-3111), a high-affinity and selective delta-opioid receptor nonpeptide agonist ligand, J MED CHEM, 42(26), 1999, pp. 5359-5368
Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands
Authors: Zhang, XY Rice, KC Calderon, SN Kayakiri, H Smith, L Coop, A Jacobson, AE Rothman, RB Davis, P Dersch, CM Porreca, F
Citation: Xy. Zhang et al., Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands, J MED CHEM, 42(26), 1999, pp. 5455-5463
Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans
Authors: Ananthan, S Kezar, HS Carter, RL Saini, SK Rice, KC Wells, JL Davis, P Xu, H Dersch, CM Bilsky, EJ Porreca, F Rothman, RB
Citation: S. Ananthan et al., Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans, J MED CHEM, 42(18), 1999, pp. 3527-3538
3-isobutyl-1-methylxanthine inhibits basal mu-opioid receptor phosphorylation and reverses acute morphine tolerance and dependence in mice
Authors: Wang, ZJ Bilsky, EJ Wang, DX Porreca, F Sadee, W
Citation: Zj. Wang et al., 3-isobutyl-1-methylxanthine inhibits basal mu-opioid receptor phosphorylation and reverses acute morphine tolerance and dependence in mice, EUR J PHARM, 371(1), 1999, pp. 1-9
Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat
Authors: Kovelowski, CJ Bian, D Hruby, VJ Lai, J Ossipov, MH Porreca, F
Citation: Cj. Kovelowski et al., Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat, BRAIN RES, 843(1-2), 1999, pp. 12-17
Loss of antiallodynic and antinociceptive spinal supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum
Authors: Bian, D Ossipov, MH Ibrahim, M Raffa, RB Tallarida, RJ Malan, TP Lai, J Porreca, F
Citation: D. Bian et al., Loss of antiallodynic and antinociceptive spinal supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum, BRAIN RES, 831(1-2), 1999, pp. 55-63
Can inflammation relieve pain?
Authors: Porreca, F Lai, J Malan, TP
Citation: F. Porreca et al., Can inflammation relieve pain?, NAT MED, 4(12), 1998, pp. 1359-1360
Risultati: 1-25 | 26-48 |