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Results: 1-15 |
Results: 15
Hypoxia and oxidative stress in breast cancer - Hypoxia signalling pathways
Authors: Pugh, CW Gleadle, J Maxwell, PH
Citation: Cw. Pugh et al., Hypoxia and oxidative stress in breast cancer - Hypoxia signalling pathways, BREAST CA R, 3(5), 2001, pp. 313-317
Insights into the role of the von Hippel-Lindau gene product - A key player in hypoxic regulation
Authors: Maxwell, PH Pugh, CW Ratcliffe, PJ
Citation: Ph. Maxwell et al., Insights into the role of the von Hippel-Lindau gene product - A key player in hypoxic regulation, EXP NEPHROL, 9(4), 2001, pp. 235-240
Activation of the HIF pathway in cancer
Authors: Maxwell, PH Pugh, CW Ratcliffe, PJ
Citation: Ph. Maxwell et al., Activation of the HIF pathway in cancer, CUR OP GEN, 11(3), 2001, pp. 293-299
Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
Authors: Masson, N Willam, C Maxwell, PH Pugh, CW Ratcliffe, PJ
Citation: N. Masson et al., Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation, EMBO J, 20(18), 2001, pp. 5197-5206
C-elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
Authors: Epstein, ACR Gleadle, JM McNeill, LA Hewitson, KS O'Rourke, J Mole, DR Mukherji, M Metzen, E Wilson, MI Dhanda, A Tian, YM Masson, N Hamilton, DL Jaakkola, P Barstead, R Hodgkin, J Maxwell, PH Pugh, CW Schofield, CJ Ratcliffe, PJ
Citation: Acr. Epstein et al., C-elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation, CELL, 107(1), 2001, pp. 43-54
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O-2-regulated prolyl hydroxylation
Authors: Jaakkola, P Mole, DR Tian, YM Wilson, MI Gielbert, J Gaskell, SJ von Kriegsheim, A Hebestreit, HF Mukherji, M Schofield, CJ Maxwell, PH Pugh, CW Ratcliffe, PJ
Citation: P. Jaakkola et al., Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O-2-regulated prolyl hydroxylation, SCIENCE, 292(5516), 2001, pp. 468-472
Selection of mutant CHO cells with constitutive activation of the HIF system and inactivation of the von Hippel-Lindau tumor suppressor
Authors: Vaux, EC Wood, SM Cockman, ME Nicholls, LG Yeates, KM Pugh, CW Maxwell, PH Ratcliffe, PJ
Citation: Ec. Vaux et al., Selection of mutant CHO cells with constitutive activation of the HIF system and inactivation of the von Hippel-Lindau tumor suppressor, J BIOL CHEM, 276(47), 2001, pp. 44323-44330
Targeting tumors through the HIF system
Authors: Ratcliffe, PJ Pugh, CW Maxwell, PH
Citation: Pj. Ratcliffe et al., Targeting tumors through the HIF system, NAT MED, 6(12), 2000, pp. 1315-1316
Increasing endothelial cell specific expression by the use of heterologoushypoxic and cytokine-inducible enhancers
Authors: Modlich, U Pugh, CW Bicknell, R
Citation: U. Modlich et al., Increasing endothelial cell specific expression by the use of heterologoushypoxic and cytokine-inducible enhancers, GENE THER, 7(10), 2000, pp. 896-902
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
Authors: Wykoff, CC Pugh, CW Maxwell, PH Harris, AL Ratcliffe, PJ
Citation: Cc. Wykoff et al., Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling, ONCOGENE, 19(54), 2000, pp. 6297-6305
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
Authors: Cockman, ME Masson, N Mole, DR Jaakkola, P Chang, GW Clifford, SC Maher, ER Pugh, CW Ratcliffe, PJ Maxwell, PH
Citation: Me. Cockman et al., Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein, J BIOL CHEM, 275(33), 2000, pp. 25733-25741
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
Authors: Wykoff, CC Beasley, NJP Watson, PH Turner, KJ Pastorek, J Sibtain, A Wilson, GD Turley, H Talks, KL Maxwell, PH Pugh, CW Ratcliffe, PJ Harris, AL
Citation: Cc. Wykoff et al., Hypoxia-inducible expression of tumor-associated carbonic anhydrases, CANCER RES, 60(24), 2000, pp. 7075-7083
The expression and distribution of the hypoxia-inducible factors HIF-1 alpha and HIF-2 alpha in normal human tissues, cancers, and tumor-associated macrophages
Authors: Talks, KL Turley, H Gatter, KC Maxwell, PH Pugh, CW Ratcliffe, PJ Harris, AL
Citation: Kl. Talks et al., The expression and distribution of the hypoxia-inducible factors HIF-1 alpha and HIF-2 alpha in normal human tissues, cancers, and tumor-associated macrophages, AM J PATH, 157(2), 2000, pp. 411-421
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
Authors: Maxwell, PH Wiesener, MS Chang, GW Clifford, SC Vaux, EC Cockman, ME Wykoff, CC Pugh, CW Maher, ER Ratcliffe, PJ
Citation: Ph. Maxwell et al., The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis, NATURE, 399(6733), 1999, pp. 271-275
Oxygen-regulated and transactivating domains in endothelial PAS protein 1:Comparison with hypoxia-inducible factor-1 alpha
Authors: O'Rourke, JF Tian, YM Ratcliffe, PJ Pugh, CW
Citation: Jf. O'Rourke et al., Oxygen-regulated and transactivating domains in endothelial PAS protein 1:Comparison with hypoxia-inducible factor-1 alpha, J BIOL CHEM, 274(4), 1999, pp. 2060-2071
Risultati: 1-15 |