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SYNTHESIS AND ANTIFOLATE ACTIVITY OF NEW TETRAHYDROQUINAZOLINE AND DIHYDROCYCLOPENTA[D]PYRIMIDINE ANALOGS OF PIRITREXIM AND TRIMETREXATE ASPOTENTIAL ANTITUMOR AND ANTIPARASITIC DRUGS
Authors: ROSOWSKY A PAPOULIS A FORSCH RA QUEENER SF
Citation: A. Rosowsky et al., SYNTHESIS AND ANTIFOLATE ACTIVITY OF NEW TETRAHYDROQUINAZOLINE AND DIHYDROCYCLOPENTA[D]PYRIMIDINE ANALOGS OF PIRITREXIM AND TRIMETREXATE ASPOTENTIAL ANTITUMOR AND ANTIPARASITIC DRUGS, Annals of oncology, 9, 1998, pp. 120-120
SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF TRICYCLIC CONFORMATIONALLY RESTRICTED TETRAHYDROPYRIDO ANNULATED FURO[2,3-D]PYRIMIDINES AS INHIBITORS OF DIHYDROFOLATE REDUCTASES
Authors: GANGJEE A ELZEIN E QUEENER SF MCGUIRE JJ
Citation: A. Gangjee et al., SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF TRICYCLIC CONFORMATIONALLY RESTRICTED TETRAHYDROPYRIDO ANNULATED FURO[2,3-D]PYRIMIDINES AS INHIBITORS OF DIHYDROFOLATE REDUCTASES, Journal of medicinal chemistry, 41(9), 1998, pp. 1409-1416
SELECTIVE PNEUMOCYSTIS-CARINII DIHYDROFOLATE-REDUCTASE INHIBITORS - DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NEW 2,4-DIAMINO-5-SUBSTITUTED-FURO[2,3-D]PYRIMIDINES
Authors: GANGJEE A GUO X QUEENER SF CODY V GALITSKY N LUFT JR PANGBORN W
Citation: A. Gangjee et al., SELECTIVE PNEUMOCYSTIS-CARINII DIHYDROFOLATE-REDUCTASE INHIBITORS - DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NEW 2,4-DIAMINO-5-SUBSTITUTED-FURO[2,3-D]PYRIMIDINES, Journal of medicinal chemistry, 41(8), 1998, pp. 1263-1271
2,4-DIAMINO-6,7-DIHYDRO-5H-CYCLOPENTA[D]PYRIMIDINE ANALOGS OF TRIMETHOPRIM AS INHIBITORS OF PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII DIHYDROFOLATE-REDUCTASE
Authors: ROSOWSKY A PAPOULIS AT QUEENER SF
Citation: A. Rosowsky et al., 2,4-DIAMINO-6,7-DIHYDRO-5H-CYCLOPENTA[D]PYRIMIDINE ANALOGS OF TRIMETHOPRIM AS INHIBITORS OF PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII DIHYDROFOLATE-REDUCTASE, Journal of medicinal chemistry, 41(6), 1998, pp. 913-918
6-SUBSTITUTED 2,4-DIAMINOPYRIDO[3,2-D]PYRIMIDINE ANALOGS OF PIRITREXIM AS INHIBITORS OF DIHYDROFOLATE-REDUCTASE FROM RAT-LIVER, PNEUMOCYSTIS-CARINII, AND TOXOPLASMA-GONDII AND AS ANTITUMOR AGENTS
Authors: GANGJEE A ZHU YM QUEENER SF
Citation: A. Gangjee et al., 6-SUBSTITUTED 2,4-DIAMINOPYRIDO[3,2-D]PYRIMIDINE ANALOGS OF PIRITREXIM AS INHIBITORS OF DIHYDROFOLATE-REDUCTASE FROM RAT-LIVER, PNEUMOCYSTIS-CARINII, AND TOXOPLASMA-GONDII AND AS ANTITUMOR AGENTS, Journal of medicinal chemistry, 41(23), 1998, pp. 4533-4541
STRUCTURE-BASED DESIGN AND SYNTHESIS OF LIPOPHILIC 2,4-DIAMINO-6-SUBSTITUTED QUINAZOLINES AND THEIR EVALUATION AS INHIBITORS OF DIHYDROFOLATE REDUCTASES AND POTENTIAL ANTITUMOR AGENTS
Authors: GANGJEE A VIDWANS AP VASUDEVAN A QUEENER SF KISLIUK RL CODY V LI RM GALITSKY N LUFT JR PANGBORN S
Citation: A. Gangjee et al., STRUCTURE-BASED DESIGN AND SYNTHESIS OF LIPOPHILIC 2,4-DIAMINO-6-SUBSTITUTED QUINAZOLINES AND THEIR EVALUATION AS INHIBITORS OF DIHYDROFOLATE REDUCTASES AND POTENTIAL ANTITUMOR AGENTS, Journal of medicinal chemistry, 41(18), 1998, pp. 3426-3434
IN-VITRO AND IN-VIVO MODELS OF PNEUMOCYSTIS-CARINII
Authors: BARTLETT MS QUEENER SF SHAW MM DURANT PJ LEE CH SMITH JW
Citation: Ms. Bartlett et al., IN-VITRO AND IN-VIVO MODELS OF PNEUMOCYSTIS-CARINII, The Journal of eukaryotic microbiology, 44(6), 1997, pp. 51-51
COMPARISON OF TERNARY COMPLEXES OF PNEUMOCYSTIS-CARINII AND WILD-TYPEHUMAN DIHYDROFOLATE-REDUCTASE WITH COENZYME NADPH AND A NOVEL CLASSICAL ANTITUMOR FURO[2,3-D]PYRIMIDINE ANTIFOLATE
Authors: CODY V GALITSKY N LUFT JR PANGBORN W GANGJEE A DEVRAJ R QUEENER SF BLAKLEY RL
Citation: V. Cody et al., COMPARISON OF TERNARY COMPLEXES OF PNEUMOCYSTIS-CARINII AND WILD-TYPEHUMAN DIHYDROFOLATE-REDUCTASE WITH COENZYME NADPH AND A NOVEL CLASSICAL ANTITUMOR FURO[2,3-D]PYRIMIDINE ANTIFOLATE, Acta crystallographica. Section D, Biological crystallography, 53, 1997, pp. 638-649
IDENTIFICATION OF VIMENTIN AS A PRIMAQUINE-BINDING PROTEIN FROM PNEUMOCYSTIS-CARINII
Authors: QUEENER SF BOLYARD LA
Citation: Sf. Queener et La. Bolyard, IDENTIFICATION OF VIMENTIN AS A PRIMAQUINE-BINDING PROTEIN FROM PNEUMOCYSTIS-CARINII, The FASEB journal, 11(9), 1997, pp. 2421-2421
CHARACTERIZATION OF RECOMBINANT PNEUMOCYSTIS-CARINII INOSINE MONOPHOSPHATE DEHYDROGENASE
Authors: NOTT JM POWELL CP QUEENER SF
Citation: Jm. Nott et al., CHARACTERIZATION OF RECOMBINANT PNEUMOCYSTIS-CARINII INOSINE MONOPHOSPHATE DEHYDROGENASE, The FASEB journal, 11(3), 1997, pp. 732-732
SYNTHESIS, ANTIPNEUMOCYSTIS CARINII ACTIVITY, AND DNA-BINDING AFFINITY OF A NEW SERIES OF CONFORMATIONAL CONSTRAINED PENTAMIDINE CONGENERS
Authors: ZHANG Q WHITE AT MALBRUE M HUANG TL QUEENER SF DONKOR IO
Citation: Q. Zhang et al., SYNTHESIS, ANTIPNEUMOCYSTIS CARINII ACTIVITY, AND DNA-BINDING AFFINITY OF A NEW SERIES OF CONFORMATIONAL CONSTRAINED PENTAMIDINE CONGENERS, The FASEB journal, 11(3), 1997, pp. 733-733
IMP DEHYDROGENASE FROM PNEUMOCYSTIS-CARINII AS A POTENTIAL-DRUG TARGET
Authors: OGARA MJ LEE CH WEINBERG GA NOTT JM QUEENER SF
Citation: Mj. Ogara et al., IMP DEHYDROGENASE FROM PNEUMOCYSTIS-CARINII AS A POTENTIAL-DRUG TARGET, Antimicrobial agents and chemotherapy, 41(1), 1997, pp. 40-48
EFFECT OF N-9-METHYLATION AND BRIDGE ATOM VARIATION ON THE ACTIVITY OF 5-SUBSTITUTED 2,4-DIAMINOPYRROLO[2,3-D]PYRIMIDINES AGAINST DIHYDROFOLATE REDUCTASES FROM PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII
Authors: GANGJEE A MAVANDADI F QUEENER SF
Citation: A. Gangjee et al., EFFECT OF N-9-METHYLATION AND BRIDGE ATOM VARIATION ON THE ACTIVITY OF 5-SUBSTITUTED 2,4-DIAMINOPYRROLO[2,3-D]PYRIMIDINES AGAINST DIHYDROFOLATE REDUCTASES FROM PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII, Journal of medicinal chemistry, 40(7), 1997, pp. 1173-1177
SYNTHESIS AND DIHYDROFOLATE-REDUCTASE INHIBITORY ACTIVITIES OF 2,4-DIAMINO-5-DEAZA AND 2,4-DIAMINO-5,10-DIDEAZA LIPOPHILIC ANTIFOLATES
Authors: GANGJEE A DEVRAJ R QUEENER SF
Citation: A. Gangjee et al., SYNTHESIS AND DIHYDROFOLATE-REDUCTASE INHIBITORY ACTIVITIES OF 2,4-DIAMINO-5-DEAZA AND 2,4-DIAMINO-5,10-DIDEAZA LIPOPHILIC ANTIFOLATES, Journal of medicinal chemistry, 40(4), 1997, pp. 470-478
SYNTHESIS AND BIOLOGICAL EVALUATION OF NONCLASSICAL 2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINES WITH NOVEL SIDE-CHAIN SUBSTITUENTS AS POTENTIAL INHIBITORS OF DIHYDROFOLATE REDUCTASES
Authors: GANGJEE A VASUDEVAN A QUEENER SF
Citation: A. Gangjee et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF NONCLASSICAL 2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINES WITH NOVEL SIDE-CHAIN SUBSTITUENTS AS POTENTIAL INHIBITORS OF DIHYDROFOLATE REDUCTASES, Journal of medicinal chemistry, 40(4), 1997, pp. 479-485
MINO-4-OXO-5-SUBSTITUTED-PYRROLO[2,3-D]PYRIMIDINES NONCLASSICAL ANTIFOLATE INHIBITORS OF THYMIDYLATE SYNTHASE (VOL 39, PG 4567, 1996)
Authors: GANGJEE A MAVANDADI F KISLIUK RL MCGUIRE JJ QUEENER SF
Citation: A. Gangjee et al., MINO-4-OXO-5-SUBSTITUTED-PYRROLO[2,3-D]PYRIMIDINES NONCLASSICAL ANTIFOLATE INHIBITORS OF THYMIDYLATE SYNTHASE (VOL 39, PG 4567, 1996), Journal of medicinal chemistry, 40(4), 1997, pp. 632-632
2,4-DIAMINOTHIENO [2,3-D]PYRIMIDINE LIPOPHILIC ANTIFOLATES AS INHIBITORS OF PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII DIHYDROFOLATE-REDUCTASE
Authors: ROSOWSKY A PAPOULIS AT QUEENER SF
Citation: A. Rosowsky et al., 2,4-DIAMINOTHIENO [2,3-D]PYRIMIDINE LIPOPHILIC ANTIFOLATES AS INHIBITORS OF PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII DIHYDROFOLATE-REDUCTASE, Journal of medicinal chemistry, 40(22), 1997, pp. 3694-3699
CONFORMATIONALLY RESTRICTED ANALOGS OF TRIMETHOPRIM - 2,6-DIAMINO-8-SUBSTITUTED PURINES AS POTENTIAL DIHYDROFOLATE-REDUCTASE INHIBITORS FROM PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII
Authors: GANGJEE A VASUDEVAN A QUEENER SF
Citation: A. Gangjee et al., CONFORMATIONALLY RESTRICTED ANALOGS OF TRIMETHOPRIM - 2,6-DIAMINO-8-SUBSTITUTED PURINES AS POTENTIAL DIHYDROFOLATE-REDUCTASE INHIBITORS FROM PNEUMOCYSTIS-CARINII AND TOXOPLASMA-GONDII, Journal of medicinal chemistry, 40(19), 1997, pp. 3032-3039
NONCLASSICAL 2,4-DIAMINO-5-ARYL-6-ETHYLPYRIMIDINE ANTIFOLATES - ACTIVITY AS INHIBITORS OF DIHYDROFOLATE-REDUCTASE FROM PNEUMOCYSTIS-CARINIIAND TOXOPLASMA-GONDII AND AS ANTITUMOR AGENTS
Authors: ROBSON C MEEK MA GRUNWALDT JD LAMBERT PA QUEENER SF SCHMIDT D GRIFFIN RJ
Citation: C. Robson et al., NONCLASSICAL 2,4-DIAMINO-5-ARYL-6-ETHYLPYRIMIDINE ANTIFOLATES - ACTIVITY AS INHIBITORS OF DIHYDROFOLATE-REDUCTASE FROM PNEUMOCYSTIS-CARINIIAND TOXOPLASMA-GONDII AND AS ANTITUMOR AGENTS, Journal of medicinal chemistry, 40(19), 1997, pp. 3040-3048
STRUCTURAL STUDIES ON BIOACTIVE COMPOUNDS .28. SELECTIVE ACTIVITY OF TRIAZENYL-SUBSTITUTED PYRIMETHAMINE DERIVATIVES AGAINST PNEUMOCYSTIS-CARINII DIHYDROFOLATE-REDUCTASE
Authors: STEVENS MFG PHILLIP KS RATHBONE DL OSHEA DM QUEENER SF SCHWALBE CH LAMBERT PA
Citation: Mfg. Stevens et al., STRUCTURAL STUDIES ON BIOACTIVE COMPOUNDS .28. SELECTIVE ACTIVITY OF TRIAZENYL-SUBSTITUTED PYRIMETHAMINE DERIVATIVES AGAINST PNEUMOCYSTIS-CARINII DIHYDROFOLATE-REDUCTASE, Journal of medicinal chemistry, 40(12), 1997, pp. 1886-1893
SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF CONFORMATIONALLY RESTRICTED, TRICYCLIC NONCLASSICAL ANTIFOLATES AS INHIBITORS OF DIHYDROFOLATE REDUCTASES
Authors: GANGJEE A SHI JF QUEENER SF
Citation: A. Gangjee et al., SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF CONFORMATIONALLY RESTRICTED, TRICYCLIC NONCLASSICAL ANTIFOLATES AS INHIBITORS OF DIHYDROFOLATE REDUCTASES, Journal of medicinal chemistry, 40(12), 1997, pp. 1930-1936
TYPES OF PNEUMOCYSTIS-CARINII DETECTED IN AIR SAMPLES
Authors: BARTLETT MS LU JJ LEE CH DURANT PJ QUEENER SF SMITH JW
Citation: Ms. Bartlett et al., TYPES OF PNEUMOCYSTIS-CARINII DETECTED IN AIR SAMPLES, The Journal of eukaryotic microbiology, 43(5), 1996, pp. 44-44
DEMONSTRATION OF ESTERASE-ACTIVITY IN PNEUMOCYSTIS-CARINII BY CLEAVAGE OF 4-METHYLUMBELLIFERYL SUBSTRATES
Authors: DURANT PJ BARTLETT MS SHAW MM QUEENER SF SMITH JW
Citation: Pj. Durant et al., DEMONSTRATION OF ESTERASE-ACTIVITY IN PNEUMOCYSTIS-CARINII BY CLEAVAGE OF 4-METHYLUMBELLIFERYL SUBSTRATES, The Journal of eukaryotic microbiology, 43(5), 1996, pp. 45-45
RING-BASED ANALOGS OF PENTAMIDINE VERSUS PNEUMOCYSTIS-CARINII PNEUMONIA IN CULTURE
Authors: DELIA TJ NAGARAJAN A QUEENER SF BARTLETT MS
Citation: Tj. Delia et al., RING-BASED ANALOGS OF PENTAMIDINE VERSUS PNEUMOCYSTIS-CARINII PNEUMONIA IN CULTURE, Bioorganic & medicinal chemistry letters, 6(19), 1996, pp. 2367-2370
SYNTHESIS AND ANTIPNEUMOCYSTIS CARINII ACTIVITY OF PIPERIDINE-LINKED AROMATIC DIIMIDAZOLINES
Authors: HUANG TL ZHANG Q WHITE AT QUEENER SF BARTLETT MS SMITH JW DONKOR IO
Citation: Tl. Huang et al., SYNTHESIS AND ANTIPNEUMOCYSTIS CARINII ACTIVITY OF PIPERIDINE-LINKED AROMATIC DIIMIDAZOLINES, Bioorganic & medicinal chemistry letters, 6(17), 1996, pp. 2087-2090
Risultati: 1-25 | 26-50 | 51-65