Authors:
Fevig, JM
Pinto, DJ
Han, Q
Quan, ML
Pruitt, JR
Jacobson, IC
Galemmo, RA
Wang, SA
Orwat, MJ
Bostrom, LL
Knabb, RM
Wong, PC
Lam, PYS
Wexler, RR
Citation: Jm. Fevig et al., Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core, BIOORG MED, 11(5), 2001, pp. 641-645
Authors:
Pinto, DJP
Orwat, MJ
Wang, SG
Fevig, JM
Quan, ML
Amparo, E
Cacciola, J
Rossi, KA
Alexander, RS
Smallwood, AM
Luettgen, JM
Liang, L
Aungst, BJ
Wright, MR
Knabb, RM
Wong, PC
Wexler, RR
Lam, PYS
Citation: Djp. Pinto et al., Discovery of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2 '- (methylsulfonyl)-[1,1 '-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa, J MED CHEM, 44(4), 2001, pp. 566-578
Authors:
Wong, PC
Crain, EJ
Knabb, RM
Meade, RP
Quan, ML
Watson, CA
Wexler, RR
Wright, MR
Slee, AM
Citation: Pc. Wong et al., Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis, J PHARM EXP, 295(1), 2000, pp. 212-218
Authors:
Wong, PC
Quan, ML
Crain, EJ
Watson, CA
Wexler, RR
Knabb, RM
Citation: Pc. Wong et al., Nonpeptide factor Xa inhibitors: I. Studies with SF303 and SK549, a new class of potent antithrombotics, J PHARM EXP, 292(1), 2000, pp. 351-357