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Results: 1-12 |
Results: 12

Authors: NEIDHART W BREU V BURRI K CLOZEL M HIRTH G KLINKHAMMER U GILLER T RAMUZ H
Citation: W. Neidhart et al., DISCOVERY OF RO-48-5695 - A POTENT MIXED ENDOTHELIN RECEPTOR ANTAGONIST OPTIMIZED FROM BOSENTAN, Bioorganic & medicinal chemistry letters, 7(17), 1997, pp. 2223-2228

Authors: ROUX S BREU V GILLER T NEIDHART W RAMUZ H COASSOLO P CLOZEL JP CLOZEL M
Citation: S. Roux et al., RO-61-1790, A NEW HYDROSOLUBLE ENDOTHELIN ANTAGONIST - GENERAL PHARMACOLOGY AND EFFECTS ON EXPERIMENTAL CEREBRAL VASOSPASM, The Journal of pharmacology and experimental therapeutics, 283(3), 1997, pp. 1110-1118

Authors: CRAMERI Y FORICHER J HENGARTNER U JENNY CJ KIENZLE F RAMUZ H SCALONE M SCHLAGETER M SCHMID R WANG SN
Citation: Y. Crameri et al., ASYMMETRIC HYDROGENATION VS RESOLUTION IN THE SYNTHESIS OF POSICOR(R), A NEW-TYPE OF CALCIUM-ANTAGONIST, Chimia, 51(6), 1997, pp. 303-305

Authors: HOPFGARTNER G VETTER W MEISTER W RAMUZ H
Citation: G. Hopfgartner et al., FRAGMENTATION OF BOSENTAN(R) (RO-47-0203) IN IONSPRAY MASS-SPECTROMETRY AFTER COLLISION-INDUCED DISSOCIATION AT LOW-ENERGY - A CASE OF RADICAL FRAGMENTATION OF AN EVEN-ELECTRON ION, Journal of mass spectrometry., 31(1), 1996, pp. 69-76

Authors: BREU V CLOZEL M BURRI K HIRTH G NEIDHART W RAMUZ H
Citation: V. Breu et al., IN-VITRO CHARACTERIZATION OF RO-46-8443, THE FIRST NONPEPTIDE ANTAGONIST SELECTIVE FOR THE ENDOTHELIN ET(B) RECEPTOR, FEBS letters, 383(1-2), 1996, pp. 37-41

Authors: NEIDHART W BREN V BUR D BURRI K CLOZEL M HIRTH G MULLER M WESSEL HP RAMUZ H
Citation: W. Neidhart et al., THE DISCOVERY OF NONPEPTIDE ENDOTHELIN RECEPTOR ANTAGONISTS - PROGRESSION TOWARDS BOSENTAN, Chimia, 50(11), 1996, pp. 519-524

Authors: ELIASON JF SAWADA R TSUKAGUCHI T KOBAYASHI K ICHIHARA S KONISHI C HORII I KURUMA I RAMUZ H
Citation: Jf. Eliason et al., THE DITHIANE RO-44-5912 ENHANCES VINBLASTINE SENSITIVITY OF DRUG-RESISTANT AND PARENTAL KB LINES IN-VIVO, European journal of cancer, 31A(13-14), 1995, pp. 2354-2361

Authors: BURRI KF BREU V CASSAL JM CLOZEL M FISCHLI W GRAY GA HIRTH G LOFFLER BM MULLER M NEIDHART W RAMUZ H TRZECIAK A
Citation: Kf. Burri et al., SULFONAMIDE-BASED ANTAGONISTS OF THE ENDOTHELIN RECEPTORS, European journal of medicinal chemistry, 30, 1995, pp. 385-389

Authors: BREU V HASHIDO K BROGER C MIYAMOTO C FURUICHI Y HAYES A KALINA B LOFFLER BM RAMUZ H CLOZEL M
Citation: V. Breu et al., SEPARABLE BINDING-SITES FOR THE NATURAL AGONIST ENDOTHELIN-1 AND THE NONPEPTIDE ANTAGONIST BOSENTAN ON HUMAN ENDOTHELIN-A RECEPTORS, European journal of biochemistry, 231(1), 1995, pp. 266-270

Authors: ELIASON JF RAMUZ H YOSHIKUBO T ISHIKAWA T YAMAMOTO T TSURUO T
Citation: Jf. Eliason et al., NOVEL DITHIANE ANALOGS OF TIAPAMIL WITH HIGH-ACTIVITY TO OVERCOME MULTIDRUG-RESISTANCE IN-VITRO, Biochemical pharmacology, 50(2), 1995, pp. 187-196

Authors: CLOZEL M BREU V GRAY GA KALINA B LOFFLER BM BURRI K CASSAL JM HIRTH G MULLER M NEIDHART W RAMUZ H
Citation: M. Clozel et al., PHARMACOLOGICAL CHARACTERIZATION OF BOSENTAN, A NEW POTENT ORALLY-ACTIVE NONPEPTIDE ENDOTHELIN RECEPTOR ANTAGONIST, The Journal of pharmacology and experimental therapeutics, 270(1), 1994, pp. 228-235

Authors: CLOZEL M BREU V BURRI K CASSAL JM FISCHLI W GRAY GA HIRTH G LOFFLER BM MULLER M NEIDHART W RAMUZ H
Citation: M. Clozel et al., PATHOPHYSIOLOGICAL ROLE OF ENDOTHELIN REVEALED BY THE 1ST ORALLY-ACTIVE ENDOTHELIN RECEPTOR ANTAGONIST, Nature, 365(6448), 1993, pp. 759-761
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