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Results: 1-25 | 26-36
Results: 1-25/36
CHIRAL PHASE-ANALYSIS OF WARFARIN ENANTIOMERS IN PATIENT PLASMA IN RELATION TO CYP2C9 GENOTYPE
Authors: HENNE KR GAEDIGK A GUPTA G LEEDER JS RETTIE AE
Citation: Kr. Henne et al., CHIRAL PHASE-ANALYSIS OF WARFARIN ENANTIOMERS IN PATIENT PLASMA IN RELATION TO CYP2C9 GENOTYPE, Journal of chromatography B. Biomedical sciences and applications, 710(1-2), 1998, pp. 143-148
ACTIVATION OF CYP2C9 BY DAPSONE AND ANALOGS
Authors: TRACY TS METZ CA KORZEKAWA KR RETTIE AE
Citation: Ts. Tracy et al., ACTIVATION OF CYP2C9 BY DAPSONE AND ANALOGS, Clinical pharmacology and therapeutics, 63(2), 1998, pp. 60-60
CYTOCHROME P450-DEPENDENT DESATURATION OF LAURIC ACID - ISOFORM SELECTIVITY AND MECHANISM OF FORMATION OF 11-DODECANOIC ACID
Authors: GUAN XM FISHER MB LANG DH ZHENG YM KOOP DR RETTIE AE
Citation: Xm. Guan et al., CYTOCHROME P450-DEPENDENT DESATURATION OF LAURIC ACID - ISOFORM SELECTIVITY AND MECHANISM OF FORMATION OF 11-DODECANOIC ACID, Chemico-biological interactions, 110(1-2), 1998, pp. 103-121
IDENTIFICATION OF A MEANDER REGION PROLINE RESIDUE CRITICAL FOR HEME-BINDING TO CYTOCHROME-P450 - IMPLICATIONS FOR THE CATALYTIC FUNCTION OF HUMAN CYP4B1
Authors: ZHENG YM FISHER MB YOKOTANI N FUJIIKURIYAMA Y RETTIE AE
Citation: Ym. Zheng et al., IDENTIFICATION OF A MEANDER REGION PROLINE RESIDUE CRITICAL FOR HEME-BINDING TO CYTOCHROME-P450 - IMPLICATIONS FOR THE CATALYTIC FUNCTION OF HUMAN CYP4B1, Biochemistry (Easton), 37(37), 1998, pp. 12847-12851
MECHANISM-BASED INACTIVATION OF HUMAN CYTOCHROME-P450 1A2 BY FURAFYLLINE - DETECTION OF A 1 1-ADDUCT TO PROTEIN AND EVIDENCE FOR THE FORMATION OF A NOVEL IMIDAZOMETHIDE INTERMEDIATE/
Authors: RACHA JK RETTIE AE KUNZE KL
Citation: Jk. Racha et al., MECHANISM-BASED INACTIVATION OF HUMAN CYTOCHROME-P450 1A2 BY FURAFYLLINE - DETECTION OF A 1 1-ADDUCT TO PROTEIN AND EVIDENCE FOR THE FORMATION OF A NOVEL IMIDAZOMETHIDE INTERMEDIATE/, Biochemistry, 37(20), 1998, pp. 7407-7419
EVALUATION OF ATYPICAL CYTOCHROME-P450 KINETICS WITH 2-SUBSTRATE MODELS - EVIDENCE THAT MULTIPLE SUBSTRATES CAN SIMULTANEOUSLY BIND TO CYTOCHROME-P450 ACTIVE-SITES
Authors: KORZEKWA KR KRISHNAMACHARY N SHOU M OGAI A PARISE RA RETTIE AE GONZALEZ FJ TRACY TS
Citation: Kr. Korzekwa et al., EVALUATION OF ATYPICAL CYTOCHROME-P450 KINETICS WITH 2-SUBSTRATE MODELS - EVIDENCE THAT MULTIPLE SUBSTRATES CAN SIMULTANEOUSLY BIND TO CYTOCHROME-P450 ACTIVE-SITES, Biochemistry, 37(12), 1998, pp. 4137-4147
ISOFORM SPECIFICITY OF TRIMETHYLAMINE N-OXYGENATION BY HUMAN FLAVIN-CONTAINING MONOOXYGENASE (FMO) AND P450 ENZYMES - SELECTIVE CATALYSIS BY FMO3
Authors: LANG DH YEUNG CK PETER RM IBARRA C GASSER R ITAGAKI K PHILPOT RM RETTIE AE
Citation: Dh. Lang et al., ISOFORM SPECIFICITY OF TRIMETHYLAMINE N-OXYGENATION BY HUMAN FLAVIN-CONTAINING MONOOXYGENASE (FMO) AND P450 ENZYMES - SELECTIVE CATALYSIS BY FMO3, Biochemical pharmacology, 56(8), 1998, pp. 1005-1012
POSITIONAL SPECIFICITY OF RABBIT CYP4B1 FOR OMEGA-HYDROXYLATION OF SHORT-MEDIUM CHAIN FATTY-ACIDS AND HYDROCARBONS
Authors: FISHER MB ZHENG YM RETTIE AE
Citation: Mb. Fisher et al., POSITIONAL SPECIFICITY OF RABBIT CYP4B1 FOR OMEGA-HYDROXYLATION OF SHORT-MEDIUM CHAIN FATTY-ACIDS AND HYDROCARBONS, Biochemical and biophysical research communications (Print), 248(2), 1998, pp. 352-355
P450-CATALYZED IN-CHAIN DESATURATION OF VALPROIC ACID - ISOFORM SELECTIVITY AND MECHANISM OF FORMATION OF DELTA(3)-VALPROIC ACID GENERATED BY BACULOVIRUS-EXPRESSED CYP3A1
Authors: FISHER MB THOMPSON SJ RIBEIRO V LECHNER MC RETTIE AE
Citation: Mb. Fisher et al., P450-CATALYZED IN-CHAIN DESATURATION OF VALPROIC ACID - ISOFORM SELECTIVITY AND MECHANISM OF FORMATION OF DELTA(3)-VALPROIC ACID GENERATED BY BACULOVIRUS-EXPRESSED CYP3A1, Archives of biochemistry and biophysics (Print), 356(1), 1998, pp. 63-70
GENETIC ASSOCIATION BETWEEN SENSITIVITY TO WARFARIN AND EXPRESSION OFCYP2C9-ASTERISK-3
Authors: STEWARD DJ HAINING RL HENNE KR DAVIS G RUSHMORE TH TRAGER WF RETTIE AE
Citation: Dj. Steward et al., GENETIC ASSOCIATION BETWEEN SENSITIVITY TO WARFARIN AND EXPRESSION OFCYP2C9-ASTERISK-3, Pharmacogenetics, 7(5), 1997, pp. 361-367
PROCHIRAL SULFIDE PROBES FOR THE ACTIVE-SITE TOPOGRAPHY OF RABBIT FLAVIN-CONTAINING MONOOXYGENASE-2 (FMO2)
Authors: FISHER MB RETTIE AE
Citation: Mb. Fisher et Ae. Rettie, PROCHIRAL SULFIDE PROBES FOR THE ACTIVE-SITE TOPOGRAPHY OF RABBIT FLAVIN-CONTAINING MONOOXYGENASE-2 (FMO2), Tetrahedron : asymmetry, 8(4), 1997, pp. 613-618
IDENTIFICATION OF ENZYMES INVOLVED IN THE METABOLISM OF ATRAZINE, TERBUTHYLAZINE, AMETRYNE, AND TERBUTRYNE IN HUMAN LIVER-MICROSOMES
Authors: LANG DH RETTIE AE BOCKER RH
Citation: Dh. Lang et al., IDENTIFICATION OF ENZYMES INVOLVED IN THE METABOLISM OF ATRAZINE, TERBUTHYLAZINE, AMETRYNE, AND TERBUTRYNE IN HUMAN LIVER-MICROSOMES, Chemical research in toxicology, 10(9), 1997, pp. 1037-1044
CORRELATION OF THE CYTOCHROME-P450 2C9 LEU(359) DEFECT WITH WARFARIN SENSITIVITY
Authors: HAINING RL STEWARD DJ HENNE KR DAVIS GA RETTIE AE
Citation: Rl. Haining et al., CORRELATION OF THE CYTOCHROME-P450 2C9 LEU(359) DEFECT WITH WARFARIN SENSITIVITY, The FASEB journal, 11(9), 1997, pp. 130-130
STRUCTURAL DETERMINANTS OF REGIOSPECIFICITY OF HUMAN CYP2C19 FOR R-WARFARIN
Authors: IBEANU GC RETTIE AE HAINING RL GHANAYEM BI GOLDSTEIN JA
Citation: Gc. Ibeanu et al., STRUCTURAL DETERMINANTS OF REGIOSPECIFICITY OF HUMAN CYP2C19 FOR R-WARFARIN, The FASEB journal, 11(9), 1997, pp. 135-135
ISOFORM-SELECTIVE MECHANISM-BASED INACTIVATION OF HUMAN P450 2A6 BY 8-METHOXYPSORALEN (8-MOP)
Authors: KOENIGS LL PETER RM THOMPSON SJ RETTIE AE TRAGER WF
Citation: Ll. Koenigs et al., ISOFORM-SELECTIVE MECHANISM-BASED INACTIVATION OF HUMAN P450 2A6 BY 8-METHOXYPSORALEN (8-MOP), The FASEB journal, 11(9), 1997, pp. 185-185
BACULOVIRUS-MEDIATED EXPRESSION AND PURIFICATION OF HUMAN FMO3 - CATALYTIC, IMMUNOCHEMICAL, AND STRUCTURAL CHARACTERIZATION
Authors: HAINING RL HUNTER AP SADEQUE AJM PHILPOT RM RETTIE AE
Citation: Rl. Haining et al., BACULOVIRUS-MEDIATED EXPRESSION AND PURIFICATION OF HUMAN FMO3 - CATALYTIC, IMMUNOCHEMICAL, AND STRUCTURAL CHARACTERIZATION, Drug metabolism and disposition, 25(7), 1997, pp. 790-797
N-OXYGENATION OF CLOZAPINE BY FLAVIN-CONTAINING MONOOXYGENASE
Authors: TUGNAIT M HAWES EM MCKAY G RETTIE AE HAINING RL MIDHA KK
Citation: M. Tugnait et al., N-OXYGENATION OF CLOZAPINE BY FLAVIN-CONTAINING MONOOXYGENASE, Drug metabolism and disposition, 25(4), 1997, pp. 524-527
MECHANISM-BASED INACTIVATION OF HUMAN LIVER CYTOCHROME-P450 2A6 BY 8-METHOXYPSORALEN
Authors: KOENIGS LL PETER RM THOMPSON SJ RETTIE AE TRAGER WF
Citation: Ll. Koenigs et al., MECHANISM-BASED INACTIVATION OF HUMAN LIVER CYTOCHROME-P450 2A6 BY 8-METHOXYPSORALEN, Drug metabolism and disposition, 25(12), 1997, pp. 1407-1415
HUMAN CYP2C9 AND CYP2A6 MEDIATE FORMATION OF THE HEPATOTOXIN 4-ENE-VALPROIC ACID
Authors: SADEQUE AJM FISHER MB KORZEKWA KR GONZALEZ FJ RETTIE AE
Citation: Ajm. Sadeque et al., HUMAN CYP2C9 AND CYP2A6 MEDIATE FORMATION OF THE HEPATOTOXIN 4-ENE-VALPROIC ACID, The Journal of pharmacology and experimental therapeutics, 283(2), 1997, pp. 698-703
FORMATION OF (R)-8-HYDROXYWARFARIN IN HUMAN LIVER-MICROSOMES - A NEW METABOLIC MARKER FOR THE (S)-MEPHENYTOIN HYDROXYLASE, P4502C19
Authors: WIENKERS LC WURDEN CJ STORCH E KUNZE KL RETTIE AE TRAGER WF
Citation: Lc. Wienkers et al., FORMATION OF (R)-8-HYDROXYWARFARIN IN HUMAN LIVER-MICROSOMES - A NEW METABOLIC MARKER FOR THE (S)-MEPHENYTOIN HYDROXYLASE, P4502C19, Drug metabolism and disposition, 24(5), 1996, pp. 610-614
3-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP FOR INHIBITORS OF CYTOCHROME P4502C9
Authors: JONES JP HE MX TRAGER WF RETTIE AE
Citation: Jp. Jones et al., 3-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP FOR INHIBITORS OF CYTOCHROME P4502C9, Drug metabolism and disposition, 24(1), 1996, pp. 1-6
ALLELIC VARIANTS OF HUMAN CYTOCHROME-P450 2C9 - BACULOVIRUS-MEDIATED EXPRESSION, PURIFICATION, STRUCTURAL CHARACTERIZATION, SUBSTRATE STEREOSELECTIVITY, AND PROCHIRAL SELECTIVITY OF THE WILD-TYPE AND I359L MUTANT FORMS
Authors: HAINING RL HUNTER AP VERONESE ME TRAGER WF RETTIE AE
Citation: Rl. Haining et al., ALLELIC VARIANTS OF HUMAN CYTOCHROME-P450 2C9 - BACULOVIRUS-MEDIATED EXPRESSION, PURIFICATION, STRUCTURAL CHARACTERIZATION, SUBSTRATE STEREOSELECTIVITY, AND PROCHIRAL SELECTIVITY OF THE WILD-TYPE AND I359L MUTANT FORMS, Archives of biochemistry and biophysics, 333(2), 1996, pp. 447-458
HUMAN VARIABILITY IN HEPATIC GLUTATHIONE S-TRANSFERASE-MEDIATED CONJUGATION OF AFLATOXIN B-1-EPOXIDE AND OTHER SUBSTRATES
Authors: SLONE DH GALLAGHER EP RAMSDELL HS RETTIE AE STAPLETON PL BERLAD LG EATON DL
Citation: Dh. Slone et al., HUMAN VARIABILITY IN HEPATIC GLUTATHIONE S-TRANSFERASE-MEDIATED CONJUGATION OF AFLATOXIN B-1-EPOXIDE AND OTHER SUBSTRATES, Pharmacogenetics, 5(4), 1995, pp. 224-233
SELECTIVITY OF FLAVIN-CONTAINING MONOOXYGENASE-5 FOR THE (S)-SULFOXIDATION OF SHORT-CHAIN ARALKYL SULFIDES
Authors: FISHER MB LAWTON MP ATTAASAFOADJEI E PHILPOT RM RETTIE AE
Citation: Mb. Fisher et al., SELECTIVITY OF FLAVIN-CONTAINING MONOOXYGENASE-5 FOR THE (S)-SULFOXIDATION OF SHORT-CHAIN ARALKYL SULFIDES, Drug metabolism and disposition, 23(12), 1995, pp. 1431-1433
SPECIAL ISSUE - MULTISUBSTRATE FLAVIN-CONTAINING MONOOXYGENASES (FMOS) - PREFACE
Authors: RETTIE AE
Citation: Ae. Rettie, SPECIAL ISSUE - MULTISUBSTRATE FLAVIN-CONTAINING MONOOXYGENASES (FMOS) - PREFACE, Chemico-biological interactions, 96(1), 1995, pp. 1-1
Risultati: 1-25 | 26-36