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Results: 1-25 | 26-26
Results: 1-25/26
IDENTIFICATION OF THE HUMAN LIVER CYTOCHROME-P450 ENZYMES INVOLVED INTHE IN-VITRO METABOLISM OF A NOVEL 5-LIPOXYGENASE INHIBITOR
Authors: MACHINIST JM MAYER MD ROBERTS EM SURBER BW RODRIGUES AD
Citation: Jm. Machinist et al., IDENTIFICATION OF THE HUMAN LIVER CYTOCHROME-P450 ENZYMES INVOLVED INTHE IN-VITRO METABOLISM OF A NOVEL 5-LIPOXYGENASE INHIBITOR, Drug metabolism and disposition, 26(10), 1998, pp. 970-976
LACK OF STEREOSPECIFICITY IN THE BINDING OF THE P2 AMINO-ACID OF RITONAVIR TO HIV PROTEASE
Authors: KEMPF DJ MOLLA A MARSH KC PARK C RODRIGUES AD KORNEYEVA M VASAVANONDA S MCDONALD E FLENTGE CA MUCHMORE S WIDEBURG NE SALDIVAR A COOPER A KATI WM STEWART KD NORBECK DW
Citation: Dj. Kempf et al., LACK OF STEREOSPECIFICITY IN THE BINDING OF THE P2 AMINO-ACID OF RITONAVIR TO HIV PROTEASE, Bioorganic & medicinal chemistry letters, 7(6), 1997, pp. 699-704
PRECLINICAL DRUG-METABOLISM IN THE AGE OF HIGH-THROUGHPUT SCREENING -AN INDUSTRIAL PERSPECTIVE
Authors: RODRIGUES AD
Citation: Ad. Rodrigues, PRECLINICAL DRUG-METABOLISM IN THE AGE OF HIGH-THROUGHPUT SCREENING -AN INDUSTRIAL PERSPECTIVE, Pharmaceutical research, 14(11), 1997, pp. 1504-1510
ABT-089 [3-(2(S)-PYRROLIDINYLMETHOXY)-2-METHYLPYRIDINE] - AN ORALLY EFFECTIVE CHOLINERGIC CHANNEL MODULATOR WITH POTENTIAL ONCE-A-DAY DOSING AND CARDIOVASCULAR SAFETY
Authors: ARNERIC SP CAMPBELL JE CARROLL S DAANEN JF HOLLADAY MW JOHNSON P LIN NH MARSH KC PETERSON B QUI YH ROBERTS EM RODRIGUES AD SULLIVAN JP TRIVEDI J WILLIAMS M
Citation: Sp. Arneric et al., ABT-089 [3-(2(S)-PYRROLIDINYLMETHOXY)-2-METHYLPYRIDINE] - AN ORALLY EFFECTIVE CHOLINERGIC CHANNEL MODULATOR WITH POTENTIAL ONCE-A-DAY DOSING AND CARDIOVASCULAR SAFETY, Drug development research, 41(1), 1997, pp. 31-43
EFFECT OF SUGAR-CANE VARIETIES QUALITY ON ITS VALUE AS CATTLE FEED
Authors: RODRIGUES AD PRIMAVESI O ESTEVES SN
Citation: Ad. Rodrigues et al., EFFECT OF SUGAR-CANE VARIETIES QUALITY ON ITS VALUE AS CATTLE FEED, Pesquisa agropecuaria brasileira, 32(12), 1997, pp. 1333-1338
[O-ETHYL C-14]PHENACETIN O-DEETHYLASE ACTIVITY IN HUMAN LIVER-MICROSOMES
Authors: RODRIGUES AD SURBER BW YAO Y WONG SL ROBERTS EM
Citation: Ad. Rodrigues et al., [O-ETHYL C-14]PHENACETIN O-DEETHYLASE ACTIVITY IN HUMAN LIVER-MICROSOMES, Drug metabolism and disposition, 25(9), 1997, pp. 1097-1100
OXIDATIVE-METABOLISM OF CLARITHROMYCIN IN THE PRESENCE OF HUMAN LIVER-MICROSOMES - MAJOR ROLE FOR THE CYTOCHROME P4503A (CYP3A) SUBFAMILY
Authors: RODRIGUES AD ROBERTS EM MULFORD DJ YAO Y OUELLET D
Citation: Ad. Rodrigues et al., OXIDATIVE-METABOLISM OF CLARITHROMYCIN IN THE PRESENCE OF HUMAN LIVER-MICROSOMES - MAJOR ROLE FOR THE CYTOCHROME P4503A (CYP3A) SUBFAMILY, Drug metabolism and disposition, 25(5), 1997, pp. 623-630
THE IN-VITRO INTERACTION OF DEXMEDETOMIDINE WITH HUMAN LIVER MICROSOMAL CYTOCHROME P4502D6 (CYP2D6)
Authors: RODRIGUES AD ROBERTS EM
Citation: Ad. Rodrigues et Em. Roberts, THE IN-VITRO INTERACTION OF DEXMEDETOMIDINE WITH HUMAN LIVER MICROSOMAL CYTOCHROME P4502D6 (CYP2D6), Drug metabolism and disposition, 25(5), 1997, pp. 651-655
IDENTIFICATION OF CYTOCHROMES P450 INVOLVED IN THE HUMAN LIVER MICROSOMAL METABOLISM OF THE THROMBOXANE A, INHIBITOR SERATRODAST (ABT-001)
Authors: KUMAR GN DUBBERKE E RODRIGUES AD ROBERTS E DENNISEN JF
Citation: Gn. Kumar et al., IDENTIFICATION OF CYTOCHROMES P450 INVOLVED IN THE HUMAN LIVER MICROSOMAL METABOLISM OF THE THROMBOXANE A, INHIBITOR SERATRODAST (ABT-001), Drug metabolism and disposition, 25(1), 1997, pp. 110-115
PHARMACOKINETIC ENHANCEMENT OF INHIBITORS OF THE HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE BY COADMINISTRATION WITH RITONAVIR
Authors: KEMPF DJ MARSH KC KUMAR G RODRIGUES AD DENISSEN JF MCDONALD E KUKULKA MJ HSU A GRANNEMAN GR BAROLDI PA SUN E PIZZUTI D PLATTNER JJ NORBECK DW LEONARD JM
Citation: Dj. Kempf et al., PHARMACOKINETIC ENHANCEMENT OF INHIBITORS OF THE HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE BY COADMINISTRATION WITH RITONAVIR, Antimicrobial agents and chemotherapy, 41(3), 1997, pp. 654-660
CYTOCHROME P450-MEDIATED METABOLISM OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN HUMAN LIVER-MICROSOMES (VOL 277, PG 423, 1996)
Authors: KUMAR GN RODRIGUES AD BUKO AM DENISSEN JF
Citation: Gn. Kumar et al., CYTOCHROME P450-MEDIATED METABOLISM OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN HUMAN LIVER-MICROSOMES (VOL 277, PG 423, 1996), The Journal of pharmacology and experimental therapeutics, 281(3), 1997, pp. 1506-1506
STRUCTURE-ACTIVITY STUDIES ON 2-METHYL-3-(2(S)-PYRROLIDINYLMETHOXY)PYRIDINE (ABT-089) - AN ORALLY BIOAVAILABLE 3-PYRIDYL ETHER NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND WITH COGNITION-ENHANCING PROPERTIES
Authors: LIN NH GUNN DE RYTHER KB GARVEY DS DONNELLYROBERTS DL DECKER MW BRIONI JD BUCKLEY MJ RODRIGUES AD MARSH KG ANDERSON DJ BUCCAFUSCO JJ PRENDERGAST MA SULLIVAN JP WILLIAMS M ARNERIC SP HOLLADAY MW
Citation: Nh. Lin et al., STRUCTURE-ACTIVITY STUDIES ON 2-METHYL-3-(2(S)-PYRROLIDINYLMETHOXY)PYRIDINE (ABT-089) - AN ORALLY BIOAVAILABLE 3-PYRIDYL ETHER NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND WITH COGNITION-ENHANCING PROPERTIES, Journal of medicinal chemistry, 40(3), 1997, pp. 385-390
[O-METHYL C-14]NAPROXEN O-DEMETHYLASE ACTIVITY IN HUMAN LIVER-MICROSOMES - EVIDENCE FOR THE INVOLVEMENT OF CYTOCHROME P4501A2 AND P4502C9 10/
Authors: RODRIGUES AD KUKULKA MJ ROBERTS EM OUELLET D RODGERS TR
Citation: Ad. Rodrigues et al., [O-METHYL C-14]NAPROXEN O-DEMETHYLASE ACTIVITY IN HUMAN LIVER-MICROSOMES - EVIDENCE FOR THE INVOLVEMENT OF CYTOCHROME P4501A2 AND P4502C9 10/, Drug metabolism and disposition, 24(1), 1996, pp. 126-136
HEPATIC PEROXISOMAL AND DRUG-METABOLIZING ACTIVITY IN CD-1 MICE AFTERORAL TREATMENT WITH A NOVEL 5-LIPOXYGENASE INHIBITOR
Authors: RODRIGUES AD MACHINIST JM
Citation: Ad. Rodrigues et Jm. Machinist, HEPATIC PEROXISOMAL AND DRUG-METABOLIZING ACTIVITY IN CD-1 MICE AFTERORAL TREATMENT WITH A NOVEL 5-LIPOXYGENASE INHIBITOR, Toxicology and applied pharmacology, 137(2), 1996, pp. 193-201
IDENTIFICATION OF THE HUMAN P450 ENZYMES INVOLVED IN LANSOPRAZOLE METABOLISM
Authors: PEARCE RE RODRIGUES AD GOLDSTEIN JA PARKINSON A
Citation: Re. Pearce et al., IDENTIFICATION OF THE HUMAN P450 ENZYMES INVOLVED IN LANSOPRAZOLE METABOLISM, The Journal of pharmacology and experimental therapeutics, 277(2), 1996, pp. 805-816
CYTOCHROME P450-MEDIATED METABOLISM OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN HUMAN LIVER-MICROSOMES
Authors: KUMAR GN RODRIGUES AD BUKO AM DENISSEN JF
Citation: Gn. Kumar et al., CYTOCHROME P450-MEDIATED METABOLISM OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN HUMAN LIVER-MICROSOMES, The Journal of pharmacology and experimental therapeutics, 277(1), 1996, pp. 423-431
IN-VITRO METABOLISM OF TERFENADINE BY A PURIFIED RECOMBINANT FUSION PROTEIN CONTAINING CYTOCHROME P4503A4 AND NADPH-P450 REDUCTASE - COMPARISON TO HUMAN LIVER-MICROSOMES AND PRECISION-CUT LIVER-TISSUE SLICES
Authors: RODRIGUES AD MULFORD OJ LEE RD SURBER BW KUKULKA MJ FERRERO JL THOMAS SB SHET MS ESTABROOK RW
Citation: Ad. Rodrigues et al., IN-VITRO METABOLISM OF TERFENADINE BY A PURIFIED RECOMBINANT FUSION PROTEIN CONTAINING CYTOCHROME P4503A4 AND NADPH-P450 REDUCTASE - COMPARISON TO HUMAN LIVER-MICROSOMES AND PRECISION-CUT LIVER-TISSUE SLICES, Drug metabolism and disposition, 23(7), 1995, pp. 765-775
REGULATION OF THE AH GENE BATTERY VIA AH RECEPTOR-DEPENDENT AND INDEPENDENT PROCESSES IN CULTURED ADULT-RAT HEPATOCYTES
Authors: XIAO GH PINAIRE JA RODRIGUES AD PROUGH RA
Citation: Gh. Xiao et al., REGULATION OF THE AH GENE BATTERY VIA AH RECEPTOR-DEPENDENT AND INDEPENDENT PROCESSES IN CULTURED ADULT-RAT HEPATOCYTES, Drug metabolism and disposition, 23(6), 1995, pp. 642-650
IN-VITRO HEPATIC-METABOLISM OF ABT-418 IN CHIMPANZEE (PAN-TROGLODYTES) - A UNIQUE PATTERN OF MICROSOMAL FLAVIN-CONTAINING MONOOXYGENASE-DEPENDENT STEREOSELECTIVE N'-OXIDATION
Authors: RODRIGUES AD KUKULKA MJ FERRERO JL CASHMAN JR
Citation: Ad. Rodrigues et al., IN-VITRO HEPATIC-METABOLISM OF ABT-418 IN CHIMPANZEE (PAN-TROGLODYTES) - A UNIQUE PATTERN OF MICROSOMAL FLAVIN-CONTAINING MONOOXYGENASE-DEPENDENT STEREOSELECTIVE N'-OXIDATION, Drug metabolism and disposition, 23(10), 1995, pp. 1143-1152
IDENTIFICATION OF THE HUMAN LIVER CYTOCHROME-P450 ENZYMES INVOLVED INTHE METABOLISM OF ZILEUTON (ABT-077) AND ITS N-DEHYDROXYLATED METABOLITE, ABBOTT-66193
Authors: MACHINIST JM MAYER MD SHET MS FERRERO JL RODRIGUES AD
Citation: Jm. Machinist et al., IDENTIFICATION OF THE HUMAN LIVER CYTOCHROME-P450 ENZYMES INVOLVED INTHE METABOLISM OF ZILEUTON (ABT-077) AND ITS N-DEHYDROXYLATED METABOLITE, ABBOTT-66193, Drug metabolism and disposition, 23(10), 1995, pp. 1163-1174
ROLE OF THE CYTOCHROME-P450-3A SUBFAMILY IN THE METABOLISM OF [C-14] TIAGABINE BY HUMAN HEPATIC MICROSOMES
Authors: BOPP BA NEQUIST GE RODRIGUES AD
Citation: Ba. Bopp et al., ROLE OF THE CYTOCHROME-P450-3A SUBFAMILY IN THE METABOLISM OF [C-14] TIAGABINE BY HUMAN HEPATIC MICROSOMES, Epilepsia, 36, 1995, pp. 159-159
SATELLITE CELLS AND MYONUCLEI IN LONG-TERM DENERVATED RAT MUSCLES
Authors: RODRIGUES AD SCHMALBRUCH H
Citation: Ad. Rodrigues et H. Schmalbruch, SATELLITE CELLS AND MYONUCLEI IN LONG-TERM DENERVATED RAT MUSCLES, The Anatomical record, 243(4), 1995, pp. 430-437
THE IN-VITRO HEPATIC-METABOLISM OF ABT-418, A CHOLINERGIC CHANNEL ACTIVATOR, IN RATS, DOGS, CYNOMOLGUS MONKEYS, AND HUMANS
Authors: RODRIGUES AD FERRERO JL AMANN MT ROTERT GA CEPA SP SURBER BW MACHINIST JM TICH NR SULLIVAN JP GARVEY DS FITZGERALD M ARNERIC SP
Citation: Ad. Rodrigues et al., THE IN-VITRO HEPATIC-METABOLISM OF ABT-418, A CHOLINERGIC CHANNEL ACTIVATOR, IN RATS, DOGS, CYNOMOLGUS MONKEYS, AND HUMANS, Drug metabolism and disposition, 22(5), 1994, pp. 788-798
USE OF IN-VITRO HUMAN METABOLISM STUDIES IN DRUG DEVELOPMENT - AN INDUSTRIAL PERSPECTIVE
Authors: RODRIGUES AD
Citation: Ad. Rodrigues, USE OF IN-VITRO HUMAN METABOLISM STUDIES IN DRUG DEVELOPMENT - AN INDUSTRIAL PERSPECTIVE, Biochemical pharmacology, 48(12), 1994, pp. 2147-2156
COMPARISON OF LEVELS OF ALDEHYDE OXIDASE WITH CYTOCHROME-P450 ACTIVITIES IN HUMAN LIVER IN-VITRO
Authors: RODRIGUES AD
Citation: Ad. Rodrigues, COMPARISON OF LEVELS OF ALDEHYDE OXIDASE WITH CYTOCHROME-P450 ACTIVITIES IN HUMAN LIVER IN-VITRO, Biochemical pharmacology, 48(1), 1994, pp. 197-200
Risultati: 1-25 | 26-26