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Results: 1-25 |
Results: 25
DISTINCT MECHANISM FOR ANTIDEPRESSANT ACTIVITY BY BLOCKADE OF CENTRALSUBSTANCE-P RECEPTORS
Authors: KRAMER MS CUTLER N FEIGHNER J SHRIVASTAVA R CARMAN J SRAMEK JJ REINES SA LIU GH SNAVELY D WYATTKNOWLES E HALE JJ MILLS SG MACCOSS M SWAIN CJ HARRISON T HILL RG HEFTI F SCOLNICK EM CASCIERI MA CHICCHI GG SADOWSKI S WILLIAMS AR HEWSON L SMITH D CARLSON EJ HARGREAVES RJ RUPNIAK NMJ
Citation: Ms. Kramer et al., DISTINCT MECHANISM FOR ANTIDEPRESSANT ACTIVITY BY BLOCKADE OF CENTRALSUBSTANCE-P RECEPTORS, Science, 281(5383), 1998, pp. 1640-1645
REVERSAL OF BEHAVIORAL AND ELECTROPHYSIOLOGICAL CORRELATES OF EXPERIMENTAL PERIPHERAL NEUROPATHY BY THE NK1 RECEPTOR ANTAGONIST GR-205171 IN RATS
Authors: CUMBERBATCH MJ WYATT A BOYCE S HILL RG RUPNIAK NMJ
Citation: Mj. Cumberbatch et al., REVERSAL OF BEHAVIORAL AND ELECTROPHYSIOLOGICAL CORRELATES OF EXPERIMENTAL PERIPHERAL NEUROPATHY BY THE NK1 RECEPTOR ANTAGONIST GR-205171 IN RATS, Neurology, 50(4), 1998, pp. 14006-14006
STRUCTURAL OPTIMIZATION AFFORDING ENYL-4-(3-OXO-1,2,4-TRIAZOL-5-YL)METHYLMORPHOLINE, A POTENT, ORALLY-ACTIVE, LONG-ACTING MORPHOLINE ACETALHUMAN NK-1 RECEPTOR ANTAGONIST
Authors: HALE JJ MILLS SG MACCOSS M FINKE PE CASCIERI MA SADOWSKI S BER E CHICCHI GG KURTZ M METZGER J EIERMANN G TSOU NN TATTERSALL FD RUPNIAK NMJ WILLIAMS AR RYCROFT W HARGREAVES R MACINTYRE DE
Citation: Jj. Hale et al., STRUCTURAL OPTIMIZATION AFFORDING ENYL-4-(3-OXO-1,2,4-TRIAZOL-5-YL)METHYLMORPHOLINE, A POTENT, ORALLY-ACTIVE, LONG-ACTING MORPHOLINE ACETALHUMAN NK-1 RECEPTOR ANTAGONIST, Journal of medicinal chemistry, 41(23), 1998, pp. 4607-4614
ENHANCED PERFORMANCE OF SPATIAL AND VISUAL RECOGNITION MEMORY TASKS BY THE SELECTIVE ACETYLCHOLINESTERASE INHIBITOR E2020 IN RHESUS-MONKEYS
Authors: RUPNIAK NMJ TYE SJ FIELD MJ
Citation: Nmj. Rupniak et al., ENHANCED PERFORMANCE OF SPATIAL AND VISUAL RECOGNITION MEMORY TASKS BY THE SELECTIVE ACETYLCHOLINESTERASE INHIBITOR E2020 IN RHESUS-MONKEYS, Psychopharmacology, 131(4), 1997, pp. 406-410
EFFECTS OF THE BRADYKININ B-1 RECEPTOR ANTAGONIST DES-ARG(9)[LEU(8)]BRADYKININ AND GENETIC DISRUPTION OF THE B-2 RECEPTOR ON NOCICEPTION INRATS AND MICE
Authors: RUPNIAK NMJ BOYCE S WEBB JK WILLIAMS AR CARLSON EJ HILL RG BORKOWSKI JA HESS JF
Citation: Nmj. Rupniak et al., EFFECTS OF THE BRADYKININ B-1 RECEPTOR ANTAGONIST DES-ARG(9)[LEU(8)]BRADYKININ AND GENETIC DISRUPTION OF THE B-2 RECEPTOR ON NOCICEPTION INRATS AND MICE, Pain, 71(1), 1997, pp. 89-97
BIOLOGICAL PROFILE OF L-745,870, A SELECTIVE ANTAGONIST WITH HIGH-AFFINITY FOR THE DOPAMINE-D4 RECEPTOR
Authors: PATEL S FREEDMAN S CHAPMAN KL EMMS F FLETCHER AE KNOWLES M MARWOOD R MCALLISTER G MYERS J PATEL S CURTIS N KULAGOWSKI JJ LEESON PD RIDGILL M GRAHAM M MATHESON S RATHBONE D WATT AP BRISTOW LJ RUPNIAK NMJ BASKIN E LYNCH JJ RAGAN CI
Citation: S. Patel et al., BIOLOGICAL PROFILE OF L-745,870, A SELECTIVE ANTAGONIST WITH HIGH-AFFINITY FOR THE DOPAMINE-D4 RECEPTOR, The Journal of pharmacology and experimental therapeutics, 283(2), 1997, pp. 636-647
IN-VITRO AND IN-VIVO PREDICTORS OF THE ANTIEMETIC ACTIVITY OF TACHYKININ NK1 RECEPTOR ANTAGONISTS
Authors: RUPNIAK NMJ TATTERSALL FD WILLIAMS AR RYCROFT W CARLSON EJ CASCIERI MA SADOWSKI S BER E HALE JJ MILLS SG MACCOSS M SEWARD E HUSCROFT I OWEN S SWAIN CJ HILL RG HARGREAVES RJ
Citation: Nmj. Rupniak et al., IN-VITRO AND IN-VIVO PREDICTORS OF THE ANTIEMETIC ACTIVITY OF TACHYKININ NK1 RECEPTOR ANTAGONISTS, European journal of pharmacology, 326(2-3), 1997, pp. 201-209
PREDICTION OF THE ANTIEMETIC ACTIVITY OF NK1 RECEPTOR ANTAGONISTS IN FERRETS BY THEIR ABILITY TO INHIBIT GR73632-INDUCED FOOT TAPPING IN GERBILS
Authors: RUPNIAK NMJ TATTERSALL FD WILLIAMS AR RYCROFT W CARLSON EJ CASCIERI MA HALE JJ MILLS SG MACCOSS M SEWARD E HUSCROFT I SWAIN CJ HILL RG HARGREAVES RJ
Citation: Nmj. Rupniak et al., PREDICTION OF THE ANTIEMETIC ACTIVITY OF NK1 RECEPTOR ANTAGONISTS IN FERRETS BY THEIR ABILITY TO INHIBIT GR73632-INDUCED FOOT TAPPING IN GERBILS, British Journal of Pharmacology, 120, 1997, pp. 363-363
EFFECT OF THE ACETYLCHOLINESTERASE INHIBITOR E2020 IN TESTS OF SPATIAL AND VISUAL RECOGNITION MEMORY IN RHESUS-MONKEYS
Authors: RUPNIAK NMJ TYE SJ FIELD MJ
Citation: Nmj. Rupniak et al., EFFECT OF THE ACETYLCHOLINESTERASE INHIBITOR E2020 IN TESTS OF SPATIAL AND VISUAL RECOGNITION MEMORY IN RHESUS-MONKEYS, British Journal of Pharmacology, 120, 1997, pp. 369-369
ENANTIOSELECTIVE INHIBITION OF THE FORMALIN PAW LATE-PHASE BY THE NK1RECEPTOR ANTAGONIST L-733,060 IN GERBILS
Authors: RUPNIAK NMJ CARLSON E BOYCE S WEBB JK HILL RG
Citation: Nmj. Rupniak et al., ENANTIOSELECTIVE INHIBITION OF THE FORMALIN PAW LATE-PHASE BY THE NK1RECEPTOR ANTAGONIST L-733,060 IN GERBILS, Pain, 67(1), 1996, pp. 189-195
INHIBITION OF PENTAGASTRIN-INDUCED PRESSOR-RESPONSE IN CONSCIOUS RATSBY THE CCK-B RECEPTOR ANTAGONIST CI-988 AND CHLORDIAZEPOXIDE
Authors: WEBB JK RUPNIAK NMJ BOYCE S
Citation: Jk. Webb et al., INHIBITION OF PENTAGASTRIN-INDUCED PRESSOR-RESPONSE IN CONSCIOUS RATSBY THE CCK-B RECEPTOR ANTAGONIST CI-988 AND CHLORDIAZEPOXIDE, Regulatory peptides, 61(1), 1996, pp. 71-76
NOCICEPTION AND INFLAMMATORY HYPERALGESIA IN B-2 BRADYKININ RECEPTOR KNOCKOUT MICE
Authors: BOYCE S RUPNIAK NMJ CARLSON EJ WEBB J BORKOWSKI JA HESS JF STRADER CD HILL RG
Citation: S. Boyce et al., NOCICEPTION AND INFLAMMATORY HYPERALGESIA IN B-2 BRADYKININ RECEPTOR KNOCKOUT MICE, Immunopharmacology, 33(1-3), 1996, pp. 333-335
ENANTIOSELECTIVE INHIBITION OF THE FORMALIN PAW LATE-PHASE BY THE NK1RECEPTOR ANTAGONIST L-773,060 IN GERBILS
Authors: RUPNIAK NMJ CARLSON E BOYCE S WEBB JK HILL RG
Citation: Nmj. Rupniak et al., ENANTIOSELECTIVE INHIBITION OF THE FORMALIN PAW LATE-PHASE BY THE NK1RECEPTOR ANTAGONIST L-773,060 IN GERBILS, British Journal of Pharmacology, 117, 1996, pp. 101-101
NOCICEPTION AND INFLAMMATORY HYPERALGESIA IN B-2 BRADYKININ RECEPTOR KNOCKOUT MICE
Authors: BOYCE S RUPNIAK NMJ CARLSON EJ WEBB JK BORKOWSKI JA HESS JF STRADER CD HILL RG
Citation: S. Boyce et al., NOCICEPTION AND INFLAMMATORY HYPERALGESIA IN B-2 BRADYKININ RECEPTOR KNOCKOUT MICE, British Journal of Pharmacology, 117, 1996, pp. 245-245
LACK OF EFFECT OF CCKB RECEPTOR ANTAGONISTS IN ETHOLOGICAL AND CONDITIONED ANIMAL SCREENS FOR ANXIOLYTIC DRUGS
Authors: DAWSON GR RUPNIAK NMJ IVERSEN SD CURNOW R TYE S STANHOPE KJ TRICKLEBANK MD
Citation: Gr. Dawson et al., LACK OF EFFECT OF CCKB RECEPTOR ANTAGONISTS IN ETHOLOGICAL AND CONDITIONED ANIMAL SCREENS FOR ANXIOLYTIC DRUGS, Psychopharmacology, 121(1), 1995, pp. 109-117
ANTINOCICEPTIVE ACTIVITY OF THE TACHYKININ NK1 RECEPTOR ANTAGONIST, CP-99,994, IN CONSCIOUS GERBILS
Authors: RUPNIAK NMJ WEBB JK WILLIAMS AR CARLSON E BOYCE S HILL RG
Citation: Nmj. Rupniak et al., ANTINOCICEPTIVE ACTIVITY OF THE TACHYKININ NK1 RECEPTOR ANTAGONIST, CP-99,994, IN CONSCIOUS GERBILS, British Journal of Pharmacology, 116(2), 1995, pp. 1937-1943
CARDIOVASCULAR EFFECTS OF ANXIOGENIC AND ANXIOLYTIC AGENTS IN CONSCIOUS RATS
Authors: WEBB JK BOYCE S RUPNIAK NMJ
Citation: Jk. Webb et al., CARDIOVASCULAR EFFECTS OF ANXIOGENIC AND ANXIOLYTIC AGENTS IN CONSCIOUS RATS, British Journal of Pharmacology, 114, 1995, pp. 282-282
BEHAVIORS ELICITED BY INFUSION OF TACHYKININ RECEPTOR AGONISTS INTO MIDBRAIN DOPAMINE REGIONS IN RATS
Authors: RUPNIAK NMJ BOYCE S JACKSON A PEARCE D
Citation: Nmj. Rupniak et al., BEHAVIORS ELICITED BY INFUSION OF TACHYKININ RECEPTOR AGONISTS INTO MIDBRAIN DOPAMINE REGIONS IN RATS, British Journal of Pharmacology, 114, 1995, pp. 315-315
L-745,337 - A SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2 ELICITS ANTINOCICEPTION BUT NOT GASTRIC-ULCERATION IN RATS
Authors: BOYCE S CHAN CC GORDON R LI CS RODGER IW WEBB JK RUPNIAK NMJ HILL RG
Citation: S. Boyce et al., L-745,337 - A SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2 ELICITS ANTINOCICEPTION BUT NOT GASTRIC-ULCERATION IN RATS, Neuropharmacology, 33(12), 1994, pp. 1609-1611
DIFFERENTIAL INHIBITION OF FOOT TAPPING AND CHROMODACRYORRHOEA IN GERBILS BY CNS PENETRANT AND NON-PENETRANT TACHYKININ NK1 RECEPTOR ANTAGONISTS
Authors: RUPNIAK NMJ WILLIAMS AR
Citation: Nmj. Rupniak et Ar. Williams, DIFFERENTIAL INHIBITION OF FOOT TAPPING AND CHROMODACRYORRHOEA IN GERBILS BY CNS PENETRANT AND NON-PENETRANT TACHYKININ NK1 RECEPTOR ANTAGONISTS, European journal of pharmacology, 265(3), 1994, pp. 179-183
NONSPECIFIC INHIBITION OF DOPAMINE-RECEPTOR AGONIST-INDUCED BEHAVIOR BY THE TACHYKININ NK1 RECEPTOR ANTAGONIST CP-99,994 IN GUINEA-PIGS
Authors: RUPNIAK NMJ JACKSON A
Citation: Nmj. Rupniak et A. Jackson, NONSPECIFIC INHIBITION OF DOPAMINE-RECEPTOR AGONIST-INDUCED BEHAVIOR BY THE TACHYKININ NK1 RECEPTOR ANTAGONIST CP-99,994 IN GUINEA-PIGS, European journal of pharmacology, 262(1-2), 1994, pp. 171-175
ANTINOCICEPTIVE AND TOXIC EFFECTS OF (-EPIBATIDINE OXALATE ATTRIBUTABLE TO NICOTINIC AGONIST ACTIVITY())
Authors: RUPNIAK NMJ PATEL S MARWOOD R WEBB J TRAYNOR JR ELLIOTT J FREEDMAN SB FLETCHER SR HILL RG
Citation: Nmj. Rupniak et al., ANTINOCICEPTIVE AND TOXIC EFFECTS OF (-EPIBATIDINE OXALATE ATTRIBUTABLE TO NICOTINIC AGONIST ACTIVITY()), British Journal of Pharmacology, 113(4), 1994, pp. 1487-1493
FAILURE OF INTRAVENOUS PENTAGASTRIN CHALLENGE TO INDUCE PANIC-LIKE EFFECTS IN RHESUS-MONKEYS
Authors: RUPNIAK NMJ SCHAFFER L SIEGL P IVERSEN SD
Citation: Nmj. Rupniak et al., FAILURE OF INTRAVENOUS PENTAGASTRIN CHALLENGE TO INDUCE PANIC-LIKE EFFECTS IN RHESUS-MONKEYS, Neuropeptides, 25(2), 1993, pp. 115-119
COGNITIVE IMPAIRMENT IN SCHIZOPHRENIA - HOW EXPERIMENTAL-MODELS USINGNONHUMAN-PRIMATES MAY ASSIST IMPROVED DRUG-THERAPY FOR NEGATIVE SYMPTOMS
Authors: RUPNIAK NMJ IVERSEN SD
Citation: Nmj. Rupniak et Sd. Iversen, COGNITIVE IMPAIRMENT IN SCHIZOPHRENIA - HOW EXPERIMENTAL-MODELS USINGNONHUMAN-PRIMATES MAY ASSIST IMPROVED DRUG-THERAPY FOR NEGATIVE SYMPTOMS, Neuropsychologia, 31(10), 1993, pp. 1133-1146
ANTINOCICEPTIVE ACTIVITY OF NK(1) RECEPTOR ANTAGONISTS - NONSPECIFIC EFFECTS OF RACEMIC RP67580
Authors: RUPNIAK NMJ BOYCE S WILLIAMS AR COOK G LONGMORE J SEABROOK GR CAESER M IVERSEN SD HILL RG
Citation: Nmj. Rupniak et al., ANTINOCICEPTIVE ACTIVITY OF NK(1) RECEPTOR ANTAGONISTS - NONSPECIFIC EFFECTS OF RACEMIC RP67580, British Journal of Pharmacology, 110(4), 1993, pp. 1607-1613
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