Authors:
Lake, BG
Edwards, AJ
Price, RJ
Phillips, BJ
Renwick, AB
Beamand, JA
Adams, TB
Citation: Bg. Lake et al., Lack of effect of furfural on unscheduled DNA synthesis in the in vivo ratand mouse hepatocyte DNA repair assays and in precision-cut human liver slices, FOOD CHEM T, 39(10), 2001, pp. 999-1011
Authors:
Subrahmanyam, V
Renwick, AB
Walters, DG
Young, PJ
Price, RJ
Tonelli, AP
Lake, BG
Citation: V. Subrahmanyam et al., Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes, DRUG META D, 29(8), 2001, pp. 1146-1155
Authors:
Andersson, TB
Sjoberg, H
Hoffmann, KJ
Boobis, AR
Watts, P
Edwards, RJ
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Goldfarb, PS
Lewis, DFV
Corcos, L
Guillouzo, A
Taavitsainen, P
Pelkonen, O
Citation: Tb. Andersson et al., An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant, DRUG META D, 29(5), 2001, pp. 712-720
Authors:
Pelkonen, O
Myllynen, P
Taavitsainen, P
Boobis, AR
Watts, P
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Guillouzo, A
Corcos, L
Goldfarb, PS
Lewis, DFV
Citation: O. Pelkonen et al., Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems, XENOBIOTICA, 31(6), 2001, pp. 321-343
Authors:
Renwick, AB
Lewis, DFV
Fulford, S
Surry, D
Williams, B
Worboys, PD
Cai, X
Wang, RW
Price, RJ
Lake, BG
Evans, DC
Citation: Ab. Renwick et al., Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4, XENOBIOTICA, 31(4), 2001, pp. 187-204
Authors:
Renwick, AB
Watts, PS
Edwards, RJ
Barton, PT
Guyonnet, I
Price, RJ
Tredger, JM
Pelkonen, O
Boobis, AR
Lake, BG
Citation: Ab. Renwick et al., Differential maintenance of cytochrome P450 enzymes in cultured precision-cut human liver slices, DRUG META D, 28(10), 2000, pp. 1202-1209
Authors:
Price, RJ
Surry, D
Renwick, AB
Meneses-Lorente, G
Lake, BG
Evans, DC
Citation: Rj. Price et al., CYP isoform induction screening in 96-well plates: use of 7-benzyloxy-4-trifluoromethylcoumarin as a substrate for studies with rat hepatocytes, XENOBIOTICA, 30(8), 2000, pp. 781-795
Authors:
Renwick, AB
Surry, D
Price, RJ
Lake, BG
Evans, DC
Citation: Ab. Renwick et al., Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms, XENOBIOTICA, 30(10), 2000, pp. 955-969
Authors:
Lake, BG
Beamand, JA
Tredger, JM
Barton, PT
Renwick, AB
Price, RJ
Citation: Bg. Lake et al., Inhibition of xenobiotic-induced genotoxicity in cultured precision-cut human and rat liver slices, MUT RES-GTE, 440(1), 1999, pp. 91-100
Authors:
Renwick, AB
Mistry, H
Barton, PT
Mallet, F
Price, RJ
Beamand, JA
Lake, BG
Citation: Ab. Renwick et al., Effect of some indole derivatives on xenobiotic metabolism and xenobiotic-induced toxicity in cultured rat liver slices, FOOD CHEM T, 37(6), 1999, pp. 609-618
Authors:
Lake, BG
Renwick, AB
Cunninghame, ME
Price, RJ
Surry, D
Evans, DC
Citation: Bg. Lake et al., Comparison of the effects of some CYP3A and other enzyme inducers on replicative DNA synthesis and cytochrome P450 isoforms in rat liver, TOXICOLOGY, 131(1), 1998, pp. 9-20