Authors:
Afzelius, L
Zamora, I
Ridderstrom, M
Andersson, TB
Karlen, A
Masimirembwa, CM
Citation: L. Afzelius et al., Competitive CYP2C9 inhibitors: Enzyme inhibition studies, protein homologymodeling, and three-dimensional quantitative structure-activity relationship analysis, MOLEC PHARM, 59(4), 2001, pp. 909-919
Authors:
Ridderstrom, M
Zamora, I
Fjellstrom, O
Andersson, TB
Citation: M. Ridderstrom et al., Analysis of selective regions in the active sites of human cytochromes P450, 2CS, 2C9, 2C18, and 2C19 homology models using GRID/CPCA, J MED CHEM, 44(24), 2001, pp. 4072-4081
Authors:
Mannervik, B
Bolton-Grob, R
Cameron, AD
Etahadieh, M
Gustafsson, A
Hansson, LO
Hubatsch, I
Jemth, P
Johansson, AS
Jones, TA
Larsson, AK
Nilsson, LO
Olin, B
Pettersson, PL
Ridderstrom, M
Stenberg, G
Widersten, M
Wisen, S
Citation: B. Mannervik et al., Evolutionary design of glutathione-linked proteins in vivo and in vitro based on sampling of modules from pre-existing structures, CHEM-BIO IN, 133(1-3), 2001, pp. 3-6
Authors:
Ridderstrom, M
Jemth, P
Cameron, AD
Mannervik, B
Citation: M. Ridderstrom et al., The active-site residue Tyr-175 in human glyoxalase II contributes to binding of glutathione derivatives, BBA-PROT ST, 1481(2), 2000, pp. 344-348
Authors:
Johansson, AS
Ridderstrom, M
Mannervik, B
Citation: As. Johansson et al., The human glutathione transferase P1-1 specific inhibitor TER 117 designedfor overcoming cytostatic-drug resistance is also a strong inhibitor of glyoxalase I, MOLEC PHARM, 57(3), 2000, pp. 619-624
Authors:
Ridderstrom, M
Masimirembwa, C
Trump-Kallmeyer, S
Ahlefelt, M
Otter, C
Anderson, TB
Citation: M. Ridderstrom et al., Arginines 97 and 108 in CYP2C9 are important determinants of the catalyticfunction, BIOC BIOP R, 270(3), 2000, pp. 983-987
Authors:
Cameron, AD
Ridderstrom, M
Olin, B
Mannervik, B
Citation: Ad. Cameron et al., Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue, STRUCT F D, 7(9), 1999, pp. 1067-1078
Authors:
Bruns, CM
Hubatsch, I
Ridderstrom, M
Mannervik, B
Tainer, JA
Citation: Cm. Bruns et al., Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products, J MOL BIOL, 288(3), 1999, pp. 427-439
Authors:
Cameron, AD
Ridderstrom, M
Olin, B
Kavarana, MJ
Creighton, DJ
Mannervik, B
Citation: Ad. Cameron et al., Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue, BIOCHEM, 38(41), 1999, pp. 13480-13490