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Results: 1-14 |
Results: 14
Nicastrin binds to membrane tethered Notch
Authors: Chen, FS Yu, G Arawaka, S Nishimura, M Kawarai, T Yu, H Tandon, A Supala, A Song, YQ Rogaeva, E Milman, P Sato, C Yu, C Janus, C Lee, J Song, LX Zhang, LL Fraser, PE St George-Hyslop, PH
Citation: Fs. Chen et al., Nicastrin binds to membrane tethered Notch, NAT CELL BI, 3(8), 2001, pp. 751-754
A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families
Authors: Athan, ES Williamson, J Ciappa, A Santana, V Romas, SN Lee, JH Rondon, H Lantigua, RA Medrano, M Torres, M Arawaka, S Rogaeva, E Song, YQ Sato, C Kawarai, T Fafel, KC Boss, MA Seltzer, WK Stern, Y St George-Hyslop, P Tycko, B Mayeux, R
Citation: Es. Athan et al., A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families, J AM MED A, 286(18), 2001, pp. 2257-2263
Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta(42) secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans
Authors: Zhang, DM Levitan, D Yu, G Nishimura, M Chen, FS Tandon, A Kawarai, T Arawaka, S Supala, A Song, YQ Rogaeva, E Liang, Y Holmes, E Milman, P Sato, C Zhang, LL St George-Hyslop, P
Citation: Dm. Zhang et al., Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta(42) secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans, NEUROREPORT, 11(14), 2000, pp. 3227-3230
Presenilin structure, function and role in Alzheimer disease
Authors: Fraser, PE Yang, DS Yu, G Levesque, L Nishimura, M Arawaka, S Serpell, LC Rogaeva, E St George-Hyslop, P
Citation: Pe. Fraser et al., Presenilin structure, function and role in Alzheimer disease, BBA-MOL BAS, 1502(1), 2000, pp. 1-15
Comparison of clinical and pathological phenotypes in two ethnically and geographically unrelated pedigrees segregating an equivalent presenilin 1 mutation
Authors: Jorge, R Mangone, C Castano, E Perandones, C Rogaeva, E St George-Hyslop, P El Hachimi, KH Foncin, JF Robinson, RG Bruni, AC
Citation: R. Jorge et al., Comparison of clinical and pathological phenotypes in two ethnically and geographically unrelated pedigrees segregating an equivalent presenilin 1 mutation, J NEUROP CL, 12(3), 2000, pp. 359-363
Familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions
Authors: Kertesz, A Kawarai, T Rogaeva, E St George-Hyslop, P Poorkaj, P Bird, TD Munoz, DG
Citation: A. Kertesz et al., Familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions, NEUROLOGY, 54(4), 2000, pp. 818-827
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and beta APP processing
Authors: Yu, G Nishimura, M Arawaka, S Levitan, D Zhang, LL Tandon, A Song, YQ Rogaeva, E Chen, FS Kawaral, T Supala, A Levesque, L Yu, H Yang, DS Holmes, E Millman, P Liang, Y Zhang, DM Xu, DH Sato, C Rogaev, E Smith, M Janus, C Zhang, YN Aebersold, R Farrer, L Sorbi, S Bruni, A Fraser, P St George-Hyslop, P
Citation: G. Yu et al., Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and beta APP processing, NATURE, 407(6800), 2000, pp. 48-54
Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells
Authors: Chen, FS Yang, DS Petanceska, S Yang, A Tandon, A Yu, G Rozmahel, R Ghiso, J Nishimura, M Zhang, DM Kawara, T Levesque, G Mills, J Levesque, L Song, YQ Rogaeva, E Westaway, D Mount, H Gandy, S St George-Hyslop, P Fraser, PE
Citation: Fs. Chen et al., Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells, J BIOL CHEM, 275(47), 2000, pp. 36794-36802
Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes
Authors: Yu, G Chen, FS Nishimura, M Steiner, H Tandon, A Kawarai, T Arawaka, S Supala, A Song, YQ Rogaeva, E Holmes, E Zhang, DM Milman, P Fraser, PE Haass, C St George-Hyslop, P
Citation: G. Yu et al., Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes, J BIOL CHEM, 275(35), 2000, pp. 27348-27353
Novel presenilin 1 mutations associated with early onset of dementia in a family with both early-onset and late-onset Alzheimer disease
Authors: Devi, G Fotiou, A Jyrinji, D Tycko, B DeArmand, S Rogaeva, E Song, YQ Medieros, H Liang, Y Orlacchio, A Williamson, J St George-Hyslop, P Mayeux, R
Citation: G. Devi et al., Novel presenilin 1 mutations associated with early onset of dementia in a family with both early-onset and late-onset Alzheimer disease, ARCH NEUROL, 57(10), 2000, pp. 1454-1457
Mutation of conserved aspartates affect maturation of presenilin 1 and presenilin 2 complexes
Authors: Yu, G Chen, F Nishimura, M Steiner, H Tandon, A Kawarai, T Arawaka, S Supar, A Song, YQ Rogaeva, E Holmes, E Zhang, M Milman, P Fraser, P Haass, C St George-Hyslop, P
Citation: G. Yu et al., Mutation of conserved aspartates affect maturation of presenilin 1 and presenilin 2 complexes, ACT NEUR SC, 102, 2000, pp. 6-11
Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex
Authors: Nishimura, M Yu, G Levesque, G Zhang, DM Ruel, L Chen, F Milman, P Holmes, E Liang, Y Kawarai, T Jo, E Supala, A Rogaeva, E Xu, DM Janus, C Levesque, L Bi, Q Duthie, M Rozmahel, R Mattila, K Lannfelt, L Westaway, D Mount, HTJ Woodgett, J Fraser, PE St George-Hyslop, P
Citation: M. Nishimura et al., Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex, NAT MED, 5(2), 1999, pp. 164-169
A presenilin-1 Thr116Asn substitution in a family with early-onset Alzheimer's disease
Authors: Romero, I Jorgensen, P Bolwig, G Fraser, PE Rogaeva, E Mann, D Havsager, AM Jorgensen, AL
Citation: I. Romero et al., A presenilin-1 Thr116Asn substitution in a family with early-onset Alzheimer's disease, NEUROREPORT, 10(11), 1999, pp. 2255-2260
Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin
Authors: Levesque, G Yu, G Nishimura, M Zhang, DM Levesque, L Yu, H Xu, D Liang, Y Rogaeva, E Ikeda, M Duthie, M Murgolo, N Wang, L VanderVere, P Bayne, ML Strader, CD Rommens, JM Fraser, PE St George-Hyslop, P
Citation: G. Levesque et al., Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin, J NEUROCHEM, 72(3), 1999, pp. 999-1008
Risultati: 1-14 |