Authors:
Eckert, A
Steiner, B
Marques, C
Leutz, S
Romig, H
Haass, C
Muller, WE
Citation: A. Eckert et al., Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation, J NEUROSC R, 64(2), 2001, pp. 183-192
Authors:
Steiner, H
Revesz, T
Neumann, M
Romig, H
Grim, MG
Pesold, B
Kretzschmar, HA
Hardy, J
Holton, JL
Baumeister, R
Houlden, H
Haass, C
Citation: H. Steiner et al., A pathogenic presenilin-1 deletion causes abberrant A beta 42 production in the absence of congophilic amyloid plaques, J BIOL CHEM, 276(10), 2001, pp. 7233-7239
Authors:
Capell, A
Steiner, H
Romig, H
Keck, S
Baader, M
Grim, MG
Baumeister, R
Haass, C
Citation: A. Capell et al., Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch, NAT CELL BI, 2(4), 2000, pp. 205-211
Authors:
Steiner, H
Kostka, M
Romig, H
Basset, G
Pesold, B
Hardy, J
Capell, A
Meyn, L
Grim, ML
Baumeister, R
Fechteler, K
Haass, C
Citation: H. Steiner et al., Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases, NAT CELL BI, 2(11), 2000, pp. 848-851
Authors:
Kulic, L
Walter, J
Multhaup, G
Teplow, DB
Baumeister, R
Romig, H
Capell, A
Steiner, H
Haass, C
Citation: L. Kulic et al., Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch, P NAS US, 97(11), 2000, pp. 5913-5918
Authors:
Okochi, M
Eimer, S
Bottcher, A
Baumeister, R
Romig, H
Walter, J
Capell, A
Steiner, H
Haass, C
Citation: M. Okochi et al., A loss of function mutant of the presenilin homologue SEL-12 undergoes aberrant endoproteolysis in Caenorhabditis elegans and increases A beta 42 generation in human cells, J BIOL CHEM, 275(52), 2000, pp. 40925-40932
Authors:
Steiner, H
Duff, K
Capell, A
Romig, H
Grim, MG
Lincoln, S
Hardy, J
Yu, X
Picciano, M
Fechteler, K
Citron, M
Kopan, R
Pesold, B
Keck, S
Baader, M
Tomita, T
Iwatsubo, T
Baumeister, R
Haass, C
Citation: H. Steiner et al., A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling, J BIOL CHEM, 274(40), 1999, pp. 28669-28673
Authors:
Steiner, H
Romig, H
Grim, MG
Philipp, U
Pesold, B
Citron, M
Baumeister, R
Haass, C
Citation: H. Steiner et al., The biological and pathological function of the presenilin-1 Delta exon 9 mutation is independent of its defect to undergo proteolytic processing, J BIOL CHEM, 274(12), 1999, pp. 7615-7618
Authors:
Steiner, H
Romig, H
Pesold, B
Philipp, U
Baader, M
Citron, M
Loetscher, H
Jacobsen, H
Haass, C
Citation: H. Steiner et al., Amyloidogenic function of the Alzheimer's disease-associated presenilin 1 in the absence of endoproteolysis, BIOCHEM, 38(44), 1999, pp. 14600-14605
Authors:
Leimer, U
Lun, K
Romig, H
Walter, J
Grunberg, J
Brand, M
Haass, C
Citation: U. Leimer et al., Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis, BIOCHEM, 38(41), 1999, pp. 13602-13609