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Results: 1-25 | 26-45
Results: 1-25/45
Hyper-IL-6 gene therapy reverses fulminant hepatic failure
Authors: Hecht, N Pappo, O Shouval, D Rose-John, S Galun, E Axelrod, JH
Citation: N. Hecht et al., Hyper-IL-6 gene therapy reverses fulminant hepatic failure, MOL THER, 3(5), 2001, pp. 683-687
Possible role of human interleukin-6 and soluble interleukin-6 receptor inhepatitis B virus infection
Authors: Heinz, D Peters, M Prange, R Gerken, G Rose-John, S
Citation: D. Heinz et al., Possible role of human interleukin-6 and soluble interleukin-6 receptor inhepatitis B virus infection, J VIRAL HEP, 8(3), 2001, pp. 186-193
IL-6 and its soluble receptor orchestrate a temporal switch in the patternof leukocyte recruitment seen during acute inflammation
Authors: Hurst, SM Wilkinson, TS McLoughlin, RM Jones, S Horiuchi, S Yamamoto, N Rose-John, S Fuller, GM Topley, N Jones, SA
Citation: Sm. Hurst et al., IL-6 and its soluble receptor orchestrate a temporal switch in the patternof leukocyte recruitment seen during acute inflammation, IMMUNITY, 14(6), 2001, pp. 705-714
The designer cytokine hyper-IL-6 mediates growth inhibition and GM-CSF-dependent rejection of B16 melanoma cells
Authors: Ozbek, S Peters, M Breuhahn, K Mann, A Blessing, M Fischer, M Schirmacher, P Mackiewicz, A Rose-John, S
Citation: S. Ozbek et al., The designer cytokine hyper-IL-6 mediates growth inhibition and GM-CSF-dependent rejection of B16 melanoma cells, ONCOGENE, 20(8), 2001, pp. 972-979
gp130-Stimulating designer cytokine Hyper-interleukin-6 synergizes with murine stroma for long-term survival of primitive human hematopoietic progenitor cells
Authors: Gotze, KS Keller, U Rose-John, S Peschel, C
Citation: Ks. Gotze et al., gp130-Stimulating designer cytokine Hyper-interleukin-6 synergizes with murine stroma for long-term survival of primitive human hematopoietic progenitor cells, EXP HEMATOL, 29(7), 2001, pp. 822-832
Interleukin-6 and the soluble interleukin-6 receptor induce stem cell factor and Flt-3L expression in vivo and in vitro
Authors: Peters, M Solem, F Goldschmidt, J Schirmacher, P Rose-John, S
Citation: M. Peters et al., Interleukin-6 and the soluble interleukin-6 receptor induce stem cell factor and Flt-3L expression in vivo and in vitro, EXP HEMATOL, 29(2), 2001, pp. 146-155
Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins
Authors: Althoff, K Mullberg, J Aasland, D Voltz, N Kallen, KJ Grotzinger, J Rose-John, S
Citation: K. Althoff et al., Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins, BIOCHEM J, 353, 2001, pp. 663-672
Structure of an extracellular gp130 cytokine receptor signaling complex
Authors: Chow, DC He, XL Snow, AL Rose-John, S Garcia, KC
Citation: Dc. Chow et al., Structure of an extracellular gp130 cytokine receptor signaling complex, SCIENCE, 291(5511), 2001, pp. 2150-2155
Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells
Authors: Audet, J Miller, CL Rose-John, S Piret, JM Eaves, CJ
Citation: J. Audet et al., Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells, P NAS US, 98(4), 2001, pp. 1757-1762
Induction of strong hepatitis B virus (HBV) specific T helper cell and cytotoxic T lymphocyte responses by therapeutic vaccination in the trimera mouse model of chronic HBV infection
Authors: Bocher, WO Dekel, B Schwerin, W Geissler, M Hoffmann, S Rohwer, A Arditti, F Cooper, A Bernhard, H Berrebi, A Rose-John, S Shaul, Y Galle, PR Lohr, HF Reisner, Y
Citation: Wo. Bocher et al., Induction of strong hepatitis B virus (HBV) specific T helper cell and cytotoxic T lymphocyte responses by therapeutic vaccination in the trimera mouse model of chronic HBV infection, EUR J IMMUN, 31(7), 2001, pp. 2071-2079
Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses
Authors: Jostock, T Mullberg, J Ozbek, S Atreya, R Blinn, G Voltz, N Fischer, M Neurath, MF Rose-John, S
Citation: T. Jostock et al., Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses, EUR J BIOCH, 268(1), 2001, pp. 160-167
Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis byindependent mechanisms
Authors: Mann, A Breuhahn, K Schirmacher, P Wilhelmi, A Beyer, C Rosenau, A Ozbek, S Rose-John, S Blessing, M
Citation: A. Mann et al., Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis byindependent mechanisms, CANCER RES, 61(5), 2001, pp. 2311-2319
In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130
Authors: Chow, DC Ho, J Pham, TLN Rose-John, S Garcia, KC
Citation: Dc. Chow et al., In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130, BIOCHEM, 40(25), 2001, pp. 7593-7603
The importance of shedding of membrane proteins for cytokine biology
Authors: Mullberg, J Althoff, K Jostock, T Rose-John, S
Citation: J. Mullberg et al., The importance of shedding of membrane proteins for cytokine biology, EUR CYTOKIN, 11(1), 2000, pp. 27-37
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo
Authors: Atreya, R Mudter, J Finotto, S Mullberg, J Jostock, T Wirtz, S Schutz, M Bartsch, B Holtmann, M Becker, C Strand, D Czaja, J Schlaak, JF Lehr, HA Autschbach, F Schurmann, G Nishimoto, N Yoshizaki, K Ito, H Kishimoto, T Galle, PR Rose-John, S Neurath, MF
Citation: R. Atreya et al., Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo, NAT MED, 6(5), 2000, pp. 583-588
An IL-6/IL-6 soluble receptor (IL-6R) hybrid protein (H-IL-6) induces epo-independent erythroid differentiation in human CD34(+) cells
Authors: Baiocchi, M Marcucci, I Rose-John, S Serlupi-Crescenzi, O Biffoni, M
Citation: M. Baiocchi et al., An IL-6/IL-6 soluble receptor (IL-6R) hybrid protein (H-IL-6) induces epo-independent erythroid differentiation in human CD34(+) cells, CYTOKINE, 12(9), 2000, pp. 1395-1399
Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury
Authors: Galun, E Zeira, E Pappo, O Peters, M Rose-John, S
Citation: E. Galun et al., Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury, FASEB J, 14(13), 2000, pp. 1979-1987
The gp130-stimulating designer cytokine hyper-IL-6 promotes the expansion of human hematopoietic progenitor cells capable to differentiate into functional dendritic cells
Authors: Bernhard, H Lohmann, M Batten, WY Metzger, J Lohr, HF Peschel, C zum Buschenfelde, KHM Rose-John, S
Citation: H. Bernhard et al., The gp130-stimulating designer cytokine hyper-IL-6 promotes the expansion of human hematopoietic progenitor cells capable to differentiate into functional dendritic cells, EXP HEMATOL, 28(4), 2000, pp. 365-372
New perspectives on the design of cytokines and growth factors
Authors: Kallen, KJ Grotzinger, J Rose-John, S
Citation: Kj. Kallen et al., New perspectives on the design of cytokines and growth factors, TRENDS BIOT, 18(11), 2000, pp. 455-461
Genetically modified tumour vaccines (GMTV) in melanoma clinical trials
Authors: Nawrocki, S Murawa, P Malicki, J Kapcinska, M Gryska, K Izycki, D Kaczmarek, A Laciak, M Czapczyk, A Karczewska, A Rose-John, S Mackiewicz, A
Citation: S. Nawrocki et al., Genetically modified tumour vaccines (GMTV) in melanoma clinical trials, IMMUNOL LET, 74(1), 2000, pp. 81-86
Soluble interleukin-6 receptor (sIL-6R) makes IL-6R negative T cell line respond to IL-6; it inhibits TNF production
Authors: Igaz, P Horvath, A Horvath, B Szalai, C Pallinger, E Rajnavolgyi, E Toth, S Rose-John, S Falus, A
Citation: P. Igaz et al., Soluble interleukin-6 receptor (sIL-6R) makes IL-6R negative T cell line respond to IL-6; it inhibits TNF production, IMMUNOL LET, 71(3), 2000, pp. 143-148
Human interleukin-6 facilitates hepatitis B virus infection in vitro and in vivo
Authors: Galun, E Nahor, G Eid, A Jurim, O Rose-John, S Blum, HE Nussbaum, O Ilan, E Daudi, N Shouval, D Reisner, Y Dagan, S
Citation: E. Galun et al., Human interleukin-6 facilitates hepatitis B virus infection in vitro and in vivo, VIROLOGY, 270(2), 2000, pp. 299-309
Generation of tumor-reactive CTL against the tumor-associated antigen HER2using retrovirally transduced dendritic cells derived from CD34(+) hemopoietic progenitor cells
Authors: zum Buschenfelde, CM Nicklisch, N Rose-John, S Peschel, C Bernhard, H
Citation: Cm. Zum Buschenfelde et al., Generation of tumor-reactive CTL against the tumor-associated antigen HER2using retrovirally transduced dendritic cells derived from CD34(+) hemopoietic progenitor cells, J IMMUNOL, 165(7), 2000, pp. 4133-4140
IL-6 receptor independent stimulation of human gp130 by viral IL-6
Authors: Mullberg, J Geib, T Jostock, T Hoischen, SH Vollmer, P Voltz, N Heinz, D Galle, PR Klouche, M Rose-John, S
Citation: J. Mullberg et al., IL-6 receptor independent stimulation of human gp130 by viral IL-6, J IMMUNOL, 164(9), 2000, pp. 4672-4677
Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration
Authors: Peters, M Blinn, G Jostock, T Schirmacher, P Zum Buschenfelde, KHM Galle, PR Rose-John, S
Citation: M. Peters et al., Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration, GASTROENTY, 119(6), 2000, pp. 1663-1671
Risultati: 1-25 | 26-45