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Results: 1-25/53
Authors:
Ulrich, T
Dersch, CM
Rothman, RB
Jacobson, AE
Rice, KC
Citation: T. Ulrich et al., Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: Variation ofthe delta address and its effects on affinity and selectivity for the delta opioid receptor, BIOORG MED, 11(21), 2001, pp. 2883-2885
Authors:
Baumann, MH
Ayestas, MA
Dersch, CM
Rothman, RB
Citation: Mh. Baumann et al., 1-(m-chlorophenyl)piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain, NEUROPSYCH, 24(5), 2001, pp. 492-501
Authors:
Xu, H
Lu, YF
Thomas, JB
Carroll, FI
Rice, KC
Rothman, RB
Citation: H. Xu et al., Opioid peptide receptor studies. 15. Relative efficacy of 4-[(N-allyl-3-methyl-4 piperidinyl) phenylamino]-N,N-diethylbenzamide and related compoundsat the cloned human delta-opioid receptor, SYNAPSE, 40(4), 2001, pp. 269-274
Authors:
Rothman, RB
Baumann, MH
Dersch, CM
Romero, DV
Rice, KC
Carroll, FI
Partilla, JS
Citation: Rb. Rothman et al., Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin, SYNAPSE, 39(1), 2001, pp. 32-41
Authors:
Xu, H
Hashimoto, A
Rice, KC
Jacobson, AE
Thomas, JB
Carroll, FI
Lai, J
Rothman, RB
Citation: H. Xu et al., Opioid peptide receptor studies. 14. Stereochemistry determines agonist efficacy and intrinsic efficacy in the [S-35]GTP-gamma-S functional binding assay, SYNAPSE, 39(1), 2001, pp. 64-69
Authors:
Xu, H
Lu, YF
Rice, KC
Ananthan, S
Rothman, RB
Citation: H. Xu et al., SoRI 9409, a non-peptide opioid mu receptor agonist/delta receptor antagonist, fails to stimulate [S-35]-GTP-gamma-S binding at cloned opioid receptors, BRAIN RES B, 55(4), 2001, pp. 507-511
Authors:
Pepper, JP
Baumann, MH
Ayestas, M
Rothman, RB
Citation: Jp. Pepper et al., Inhibition of MAO-A fails to alter cocaine-induced increases in extracellular dopamine and norepinephrine in rat nucleus accumbens, MOL BRAIN R, 87(2), 2001, pp. 184-189
Authors:
Baumann, MH
Rothman, RB
Pablo, JP
Mash, DC
Citation: Mh. Baumann et al., In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats, J PHARM EXP, 297(2), 2001, pp. 531-539
Authors:
McLamore, S
Ullrich, T
Rothman, RB
Xu, H
Dersch, C
Coop, A
Davis, P
Porreca, F
Jacobson, AE
Rice, KC
Citation: S. Mclamore et al., Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5 alpha-epoxy-3,14-dihydroxy-6,7 : 2 ',3 '-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy, J MED CHEM, 44(9), 2001, pp. 1471-1474
Authors:
Thomas, JB
Herault, XM
Rothman, RB
Atkinson, RN
Burgess, JP
Mascarella, SW
Dersch, CM
Xu, H
Flippen-Anderson, JL
George, CF
Carroll, FI
Citation: Jb. Thomas et al., Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl) arylamino]-N,N-diethylbenzamides, J MED CHEM, 44(6), 2001, pp. 972-987
Authors:
Zhang, Y
Joseph, DB
Bowen, WD
Flippen-Anderson, JL
Dersch, CM
Rothman, RB
Jacobson, AE
Rice, KC
Citation: Y. Zhang et al., Synthesis and biological evaluation of tropane-like 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl) piperazine (GBR 12909) analogues, J MED CHEM, 44(23), 2001, pp. 3937-3945
Authors:
Thomas, JB
Atkinson, RN
Rothman, RB
Fix, SE
Mascarella, SW
Vinson, NA
Xu, H
Dersch, CM
Lu, YF
Cantrell, BE
Zimmerman, DM
Carroll, FI
Citation: Jb. Thomas et al., Identification of the first trans-(3R,4R)-dimethyl-4-(3-hydroxyphenyl)piperidine derivative to possess highly potent and selective opioid kappa receptor antagonist activity, J MED CHEM, 44(17), 2001, pp. 2687-2690
Authors:
Yu, H
Rothman, RB
Dersch, CM
Partilla, JS
Rice, KC
Citation: H. Yu et al., Uptake and release effects of diethylpropion and its metabolites with biogenic amine transporters, BIO MED CH, 8(12), 2000, pp. 2689-2692
Authors:
Thomas, JB
Atkinson, RN
Rothman, RB
Burgess, JP
Mascarella, SW
Dersch, CM
Xu, H
Carroll, FI
Citation: Jb. Thomas et al., 4-[(8-alkyl-8-azabicyclo[3.2.1]octyl-3-yl)-3-arylanilino]-N,N-diethylbenzamides: High affinity, selective ligands for the delta opioid receptor illustrate factors important to antagonist activity, BIOORG MED, 10(11), 2000, pp. 1281-1284
Authors:
Baumann, MH
Ayestas, MA
Dersch, CM
Brockington, A
Rice, KC
Rothman, RB
Citation: Mh. Baumann et al., Effects of phentermine and fenfluramine on extracellular dopamine and serotonin in rat nucleus accumbens: Therapeutic implications, SYNAPSE, 36(2), 2000, pp. 102-113
Authors:
Rothman, RB
Partilla, JS
Baumann, MH
Dersch, CM
Carroll, FI
Rice, KC
Citation: Rb. Rothman et al., Neurochemical neutralization of methamphetamine with high-affinity nonselective inhibitors of biogenic amine transporters: A pharmacological strategyfor treating stimulant abuse, SYNAPSE, 35(3), 2000, pp. 222-227
Authors:
Rothman, RB
Gorelick, DA
Heishman, SJ
Eichmiller, PR
Hill, BH
Norbeck, J
Liberto, JG
Citation: Rb. Rothman et al., An open-label study of a functional opioid kappa antagonist in the treatment of opioid dependence, J SUBST ABU, 18(3), 2000, pp. 277-281
Authors:
Baumann, MH
Rothman, RB
Ali, SF
Citation: Mh. Baumann et al., Comparative neurobiological effects of ibogaine and MK-801 in rats, DRUG AL DEP, 59(2), 2000, pp. 143-151
Authors:
Partilla, JS
Dersch, CM
Yu, H
Rice, KC
Rothman, RB
Citation: Js. Partilla et al., Neurochemical neutralization of amphetamine-type stimulants in rat brain by the indatraline analog (-)-HY038, BRAIN RES B, 53(6), 2000, pp. 821-826
Authors:
Heyliger, SO
Ni, Q
Rothman, RB
Citation: So. Heyliger et al., Resolution of two [S-35]GTP-gamma-S binding sites and their response to chronic morphine treatment: A binding surface analysis, BRAIN RES B, 51(4), 2000, pp. 357-362
Authors:
Rothman, RB
Carroll, FI
Citation: Rb. Rothman et Fi. Carroll, Opportunities for medication development in obesity, DRUG DEV R, 51(2), 2000, pp. 49-51
Authors:
Rothman, RB
Baumann, MH
Citation: Rb. Rothman et Mh. Baumann, Neurochemical mechanisms of phentermine and fenfluramine: Therapeutic and adverse effects, DRUG DEV R, 51(2), 2000, pp. 52-65
Authors:
Zhang, Y
Rothman, RB
Dersch, CM
de Costa, BR
Jacobson, AE
Rice, KC
Citation: Y. Zhang et al., Synthesis and transporter binding properties of bridged piperazine analogues of 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine (GBR 12909), J MED CHEM, 43(25), 2000, pp. 4840-4849
Authors:
Gu, XH
Yu, H
Jacobson, AE
Rothman, RB
Dersch, CM
George, C
Flippen-Anderson, JL
Rice, KC
Citation: Xh. Gu et al., Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline, J MED CHEM, 43(25), 2000, pp. 4868-4876
Authors:
Furness, MS
Zhang, XY
Coop, A
Jacobson, AE
Rothman, RB
Dersch, CM
Xu, H
Porreca, F
Rice, KC
Citation: Ms. Furness et al., Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective delta-opioid receptor agonists from 4-[(alpha R)-alpha-(2S,5R)-4-substituted-2,5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers, J MED CHEM, 43(16), 2000, pp. 3193-3196