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Results: 1-12 |
Results: 12
An invasive cleavage assay for direct quantitation of specific RNAs
Authors: Eis, PS Olson, MC Takova, T Curtis, ML Olson, SM Vener, TI Ip, HS Vedvik, KL Bartholomay, CT Allawi, HT Ma, WP Hall, JG Morin, MD Rushmore, TH Lyamichev, VI Kwiatkowski, RW
Citation: Ps. Eis et al., An invasive cleavage assay for direct quantitation of specific RNAs, NAT BIOTECH, 19(7), 2001, pp. 673-676
In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelicvariant forms of human liver microsomal cytochrome P4502C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics
Authors: Tang, CY Shou, MG Rushmore, TH Mei, Q Sandhu, P Woolf, EJ Rose, MJ Gelmann, A Greenberg, HE De Lepeleire, I Van Hecken, A De Schepper, PJ Ebel, DL Schwartz, JI Rodrigues, AD
Citation: Cy. Tang et al., In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelicvariant forms of human liver microsomal cytochrome P4502C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics, PHARMACOGEN, 11(3), 2001, pp. 223-235
Halothane-induced liver injury in outbred guinea pigs: Role of trifluoroacetylated protein adducts in animal susceptibility
Authors: Bourdi, M Amouzadeh, HR Rushmore, TH Martin, JL Pohl, LR
Citation: M. Bourdi et al., Halothane-induced liver injury in outbred guinea pigs: Role of trifluoroacetylated protein adducts in animal susceptibility, CHEM RES T, 14(4), 2001, pp. 362-370
Substrate inhibition kinetics for cytochrome P450-catalyzed reactions
Authors: Lin, Y Lu, P Tang, C Mei, Q Sandig, G Rodrigues, AD Rushmore, TH Shou, M
Citation: Y. Lin et al., Substrate inhibition kinetics for cytochrome P450-catalyzed reactions, DRUG META D, 29(4), 2001, pp. 368-374
Testosterone, 7-benzyloxyquinoline, and 7-benzyloxy-40trifluoromethyl-coumarin bind to different domains within the active site of cytochrome P450 3A4
Authors: Lu, P Lin, Y Rodrigues, AD Rushmore, TH Baillie, TA Shou, MG
Citation: P. Lu et al., Testosterone, 7-benzyloxyquinoline, and 7-benzyloxy-40trifluoromethyl-coumarin bind to different domains within the active site of cytochrome P450 3A4, DRUG META D, 29(11), 2001, pp. 1473-1479
A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4
Authors: Shou, M Dai, R Cui, D Korzekwa, KR Baillie, TA Rushmore, TH
Citation: M. Shou et al., A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4, J BIOL CHEM, 276(3), 2001, pp. 2256-2262
Major role of human liver microsomal cytochrome p450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor
Authors: Tang, CY Shou, MG Mei, Q Rushmore, TH Rodrigues, AD
Citation: Cy. Tang et al., Major role of human liver microsomal cytochrome p450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor, J PHARM EXP, 293(2), 2000, pp. 453-459
Mechanism-based inactivation of cytochrome P450 3A4 by L-754,394
Authors: Lightning, LK Jones, JP Friedberg, T Pritchard, MP Shou, M Rushmore, TH Trager, WF
Citation: Lk. Lightning et al., Mechanism-based inactivation of cytochrome P450 3A4 by L-754,394, BIOCHEM, 39(15), 2000, pp. 4276-4287
Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives
Authors: Shou, MG Mei, Q Ettore, MW Dai, RK Baillie, TA Rushmore, TH
Citation: Mg. Shou et al., Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives, BIOCHEM J, 340, 1999, pp. 845-853
Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: Identification of glutathione conjugated metabolites
Authors: Tang, W Stearns, RA Bandiera, SM Zhang, Y Raab, C Braun, MP Dean, DC Pang, JM Leung, KH Doss, GA Strauss, JR Kwei, GY Rushmore, TH Chiu, SHL Baillie, TA
Citation: W. Tang et al., Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: Identification of glutathione conjugated metabolites, DRUG META D, 27(3), 1999, pp. 365-372
Role of a potent inhibitory monoclonal antibody to cytochrome P-450 3A4 inassessment of human drug metabolism
Authors: Mei, Q Tang, CY Assang, C Lin, Y Slaughter, D Rodrigues, AD Baillie, TA Rushmore, TH Shou, MG
Citation: Q. Mei et al., Role of a potent inhibitory monoclonal antibody to cytochrome P-450 3A4 inassessment of human drug metabolism, J PHARM EXP, 291(2), 1999, pp. 749-759
Electrospray ionization mass spectrometric analysis of intact cytochrome P450: Identification of tienilic acid adducts to P450 2C9
Authors: Koenigs, LL Peter, RM Hunter, AP Haining, RL Rettie, AE Friedberg, T Pritchard, MP Shou, M Rushmore, TH Trager, WF
Citation: Ll. Koenigs et al., Electrospray ionization mass spectrometric analysis of intact cytochrome P450: Identification of tienilic acid adducts to P450 2C9, BIOCHEM, 38(8), 1999, pp. 2312-2319
Risultati: 1-12 |