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Results: 1-15 |
Results: 15
DOWN-REGULATION OF PS1 EXPRESSION IN NEURONS DECREASES BETA-AMYLOID PRODUCTION - A BIOCHEMICAL LINK BETWEEN THE 2 MAJOR FAMILIAL ALZHEIMERS-DISEASE GENES
Authors: SAFTIG P DESTROOPER B
Citation: P. Saftig et B. Destrooper, DOWN-REGULATION OF PS1 EXPRESSION IN NEURONS DECREASES BETA-AMYLOID PRODUCTION - A BIOCHEMICAL LINK BETWEEN THE 2 MAJOR FAMILIAL ALZHEIMERS-DISEASE GENES, Molecular psychiatry, 3(4), 1998, pp. 287-289
POTENTIAL ROLE FOR CATHEPSIN-D IN P53-DEPENDENT TUMOR SUPPRESSION ANDCHEMOSENSITIVITY
Authors: WU GS SAFTIG P PETERS C ELDEIRY WS
Citation: Gs. Wu et al., POTENTIAL ROLE FOR CATHEPSIN-D IN P53-DEPENDENT TUMOR SUPPRESSION ANDCHEMOSENSITIVITY, Oncogene, 16(17), 1998, pp. 2177-2183
DESTABILIZATION OF BETA-CATENIN BY MUTATIONS IN PRESENILIN-1 POTENTIATES NEURONAL APOPTOSIS
Authors: ZHANG ZH HARTMANN H DO VM ABRAMOWSKI D STURCHLERPIERRAT C STAUFENBIEL M SOMMER B VANDEWETERING M CLEVERS H SAFTIG P DESTROOPER B HE X YANKNER BA
Citation: Zh. Zhang et al., DESTABILIZATION OF BETA-CATENIN BY MUTATIONS IN PRESENILIN-1 POTENTIATES NEURONAL APOPTOSIS, Nature, 395(6703), 1998, pp. 698-702
DEFICIENCY OF PRESENILIN-1 INHIBITS THE NORMAL CLEAVAGE OF AMYLOID PRECURSOR PROTEIN
Authors: DESTROOPER B SAFTIG P CRAESSAERTS K VANDERSTICHELE H GUHDE G ANNAERT W VONFIGURA K VANLEUVEN F
Citation: B. Destrooper et al., DEFICIENCY OF PRESENILIN-1 INHIBITS THE NORMAL CLEAVAGE OF AMYLOID PRECURSOR PROTEIN, Nature, 391(6665), 1998, pp. 387-390
CATHEPSIN-B AND CATHEPSIN-D ARE DISPENSABLE FOR MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II-MEDIATED ANTIGEN PRESENTATION
Authors: DEUSSING J ROTH W SAFTIG P PETERS C PLOEGH HL VILLADANGOS JA
Citation: J. Deussing et al., CATHEPSIN-B AND CATHEPSIN-D ARE DISPENSABLE FOR MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II-MEDIATED ANTIGEN PRESENTATION, Proceedings of the National Academy of Sciences of the United Statesof America, 95(8), 1998, pp. 4516-4521
IMPAIRED OSTEOCLASTIC BONE-RESORPTION LEADS TO OSTEOPETROSIS IN CATHEPSIN-K-DEFICIENT MICE
Authors: SAFTIG P HUNZIKER E WEHMEYER O JONES S BOYDE A ROMMERSKIRCH W MORITZ JD SCHU P VONFIGURA K
Citation: P. Saftig et al., IMPAIRED OSTEOCLASTIC BONE-RESORPTION LEADS TO OSTEOPETROSIS IN CATHEPSIN-K-DEFICIENT MICE, Proceedings of the National Academy of Sciences of the United Statesof America, 95(23), 1998, pp. 13453-13458
NONCONVENTIONAL ROLE OF LYSOSOMAL ACID-PHOSPHATASE IN OLFACTORY RECEPTOR AXONS - COLOCALIZATION WITH GROWTH-ASSOCIATED PHOSPHOPROTEIN-43
Authors: WOLFF JR LIU WL BOTTCHER H KRIZBAI I JOO F SAFTIG P PARDUCZ A
Citation: Jr. Wolff et al., NONCONVENTIONAL ROLE OF LYSOSOMAL ACID-PHOSPHATASE IN OLFACTORY RECEPTOR AXONS - COLOCALIZATION WITH GROWTH-ASSOCIATED PHOSPHOPROTEIN-43, Neuroscience, 79(3), 1997, pp. 887-891
ARYLSULFATASE A DEFICIENT MICE A MODEL FOR SULFATIDE LIPIDOSIS
Authors: HESS B SAFTIG P HARTMANN D COENEN R LULLMANNRAUCH R GOEBEL HH EVERS M VONFIGURA K DHOOGE R NAGELS G DEDEYN P PETERS C GIESELMANN V
Citation: B. Hess et al., ARYLSULFATASE A DEFICIENT MICE A MODEL FOR SULFATIDE LIPIDOSIS, Journal of neurochemistry, 69, 1997, pp. 95-95
MICE DEFICIENT IN LYSOSOMAL ACID-PHOSPHATASE DEVELOP LYSOSOMAL STORAGE IN THE KIDNEY AND CENTRAL-NERVOUS-SYSTEM
Authors: SAFTIG P HARTMANN D LULLMANNRAUCH R WOLFF J EVERS M KOSTER A HETMAN M VONFIGURA K PETERS C
Citation: P. Saftig et al., MICE DEFICIENT IN LYSOSOMAL ACID-PHOSPHATASE DEVELOP LYSOSOMAL STORAGE IN THE KIDNEY AND CENTRAL-NERVOUS-SYSTEM, The Journal of biological chemistry, 272(30), 1997, pp. 18628-18635
PHENOTYPE OF ARYLSULFATASE A-DEFICIENT MICE - RELATIONSHIP TO HUMAN METACHROMATIC LEUKODYSTROPHY
Authors: HESS B SAFTIG P HARTMANN D COENEN R LULLMANNRAUCH R GOEBEL HH EVERS M VONFIGURA K DHOOGE R NAGELS G DEDEYN P PETERS C GIESELMANN V
Citation: B. Hess et al., PHENOTYPE OF ARYLSULFATASE A-DEFICIENT MICE - RELATIONSHIP TO HUMAN METACHROMATIC LEUKODYSTROPHY, Proceedings of the National Academy of Sciences of the United Statesof America, 93(25), 1996, pp. 14821-14826
TARGETED DISRUPTION OF THE ARYLSULFATASE-B GENE RESULTS IN MICE RESEMBLING THE PHENOTYPE OF MUCOPOLYSACCHARIDOSIS-VI
Authors: EVERS M SAFTIG P SCHMIDT P HAFNER A MCLOGHLIN DB SCHMAHL W HESS B VONFIGURA K PETERS C
Citation: M. Evers et al., TARGETED DISRUPTION OF THE ARYLSULFATASE-B GENE RESULTS IN MICE RESEMBLING THE PHENOTYPE OF MUCOPOLYSACCHARIDOSIS-VI, Proceedings of the National Academy of Sciences of the United Statesof America, 93(16), 1996, pp. 8214-8219
AMYLOIDOGENIC PROCESSING OF HUMAN AMYLOID PRECURSOR PROTEIN IN HIPPOCAMPAL-NEURONS DEVOID OF CATHEPSIN-D
Authors: SAFTIG P PETERS C VONFIGURA K CRAESSAERTS K VANLEUVEN F DESTROOPER B
Citation: P. Saftig et al., AMYLOIDOGENIC PROCESSING OF HUMAN AMYLOID PRECURSOR PROTEIN IN HIPPOCAMPAL-NEURONS DEVOID OF CATHEPSIN-D, The Journal of biological chemistry, 271(44), 1996, pp. 27241-27244
MICE DEFICIENT FOR THE LYSOSOMAL PROTEINASE CATHEPSIN-D EXHIBIT PROGRESSIVE ATROPHY OF THE INTESTINAL-MUCOSA AND PROFOUND DESTRUCTION OF LYMPHOID-CELLS
Authors: SAFTIG P HETMAN M SCHMAHL W WEBER K HEINE L MOSSMANN H KOSTER A HESS B EVERS M VONFIGURA K PETERS C
Citation: P. Saftig et al., MICE DEFICIENT FOR THE LYSOSOMAL PROTEINASE CATHEPSIN-D EXHIBIT PROGRESSIVE ATROPHY OF THE INTESTINAL-MUCOSA AND PROFOUND DESTRUCTION OF LYMPHOID-CELLS, EMBO journal, 14(15), 1995, pp. 3599-3608
MOUSE CATHEPSIN-D GENE - MOLECULAR-ORGANIZATION, CHARACTERIZATION OF THE PROMOTER, AND CHROMOSOMAL LOCALIZATION
Authors: HETMAN M PERSCHL A SAFTIG P VONFIGURA K PETERS C
Citation: M. Hetman et al., MOUSE CATHEPSIN-D GENE - MOLECULAR-ORGANIZATION, CHARACTERIZATION OF THE PROMOTER, AND CHROMOSOMAL LOCALIZATION, DNA and cell biology, 13(4), 1994, pp. 419-427
TARGETED DISRUPTION OF THE M(R) 46-000 MANNOSE 6-PHOSPHATE RECEPTOR GENE IN MICE RESULTS IN MISROUTING OF LYSOSOMAL PROTEINS
Authors: KOSTER A SAFTIG P MATZNER U VONFIGURA K PETERS C POHLMANN R
Citation: A. Koster et al., TARGETED DISRUPTION OF THE M(R) 46-000 MANNOSE 6-PHOSPHATE RECEPTOR GENE IN MICE RESULTS IN MISROUTING OF LYSOSOMAL PROTEINS, EMBO journal, 12(13), 1993, pp. 5219-5223
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