Citation: Cw. Carreras et Dv. Santi, ENGINEERING OF MODULAR POLYKETIDE SYNTHASES TO PRODUCE NOVEL POLYKETIDES, Current opinion in biotechnology, 9(4), 1998, pp. 403-411
Authors:
BIRDSALL DL
HUANG W
SANTI DV
STROUD RM
FINERMOORE J
Citation: Dl. Birdsall et al., THE SEPARATE EFFECTS OF E60Q IN LACTOBACILLUS-CASEI THYMIDYLATE SYNTHASE DELINEATE BETWEEN MECHANISMS FOR FORMATION OF INTERMEDIATES IN CATALYSIS, Protein engineering, 11(3), 1998, pp. 171-183
Authors:
KEALEY JT
LIU L
SANTI DV
BETLACH MC
BARR PJ
Citation: Jt. Kealey et al., PRODUCTION OF A POLYKETIDE NATURAL PRODUCT IN NONPOLYKETIDE-PRODUCINGPROKARYOTIC AND EUKARYOTIC HOSTS, Proceedings of the National Academy of Sciences of the United Statesof America, 95(2), 1998, pp. 505-509
Authors:
FINERMOORE JS
LIU L
BIRDSALL DL
BREM R
APFELD J
SANTI DV
STROUD RM
Citation: Js. Finermoore et al., CONTRIBUTIONS OF ORIENTATION AND HYDROGEN-BONDING TO CATALYSIS IN ASN229 MUTANTS OF THYMIDYLATE SYNTHASE, Journal of Molecular Biology, 276(1), 1998, pp. 113-129
Authors:
GOPAL B
PRASANNA V
PARTHASARATHY S
SANTI DV
BALARAM P
MURTHY MRN
Citation: B. Gopal et al., CRYSTALS OF A THYMIDYLATE SYNTHASE MUTANT OFFER INSIGHTS INTO CRYSTALPACKING AND PLASTICITY OF PROTEIN-PROTEIN CONTACTS, Current Science (Bangalore), 75(3), 1998, pp. 299-304
Authors:
HUANG LX
KU J
POOKANJANATAVIP M
GU XR
WANG D
GREENE PJ
SANTI DV
Citation: Lx. Huang et al., IDENTIFICATION OF 2 ESCHERICHIA-COLI PSEUDOURIDINE SYNTHASES THAT SHOW MULTISITE SPECIFICITY FOR 23S RNA, Biochemistry (Easton), 37(45), 1998, pp. 15951-15957
Authors:
STOUT TJ
SCHELLENBERGER U
SANTI DV
STROUD RM
Citation: Tj. Stout et al., CRYSTAL-STRUCTURES OF A UNIQUE THERMAL-STABLE THYMIDYLATE SYNTHASE FROM BACILLUS-SUBTILIS, Biochemistry (Easton), 37(42), 1998, pp. 14736-14747
Citation: G. Chiericatti et Dv. Santi, ASPARTATE-221 OF THYMIDYLATE SYNTHASE IS INVOLVED IN FOLATE COFACTOR BINDING AND IN CATALYSIS, Biochemistry, 37(25), 1998, pp. 9038-9042
Authors:
HUANG LX
POOKANJANATAVIP M
GU XG
SANTI DV
Citation: Lx. Huang et al., A CONSERVED ASPARTATE OF TRANSFER-RNA PSEUDOURIDINE SYNTHASE IS ESSENTIAL FOR ACTIVITY AND A PROBABLE NUCLEOPHILIC CATALYST, Biochemistry, 37(1), 1998, pp. 344-351
Citation: Je. Barrett et al., TRAPPING OF THE C5 METHYLENE INTERMEDIATE IN THYMIDYLATE SYNTHASE, Journal of the American Chemical Society, 120(2), 1998, pp. 449-450
Citation: J. Ku et al., EXPRESSION OF A FUNCTIONAL NONRIBOSOMAL PEPTIDE SYNTHETASE MODULE IN ESCHERICHIA-COLI BY COEXPRESSION WITH A PHOSPHOPANTETHEINYL TRANSFERASE, Chemistry & biology, 4(3), 1997, pp. 203-207
Authors:
YAO LJ
JAMES TL
KEALEY JT
SANTI DV
SCHMITZ U
Citation: Lj. Yao et al., THE DYNAMIC NMR STRUCTURE OF THE T-PSI-C-LOOP - IMPLICATIONS FOR THE SPECIFICITY OF TRANSFER-RNA METHYLATION, Journal of biomolecular NMR, 9(3), 1997, pp. 229-244
Citation: Pg. Foster et al., THE CRYSTAL-STRUCTURE OF ESCHERICHIA-COLI TRANSFER-RNA PSEUDOURIDINE SYNTHASE-I, The FASEB journal, 11(9), 1997, pp. 28-28
Authors:
GSCHWEND DA
SIRAWARAPORN W
SANTI DV
KUNTZ ID
Citation: Da. Gschwend et al., SPECIFICITY IN STRUCTURE-BASED DRUG DESIGN - IDENTIFICATION OF A NOVEL, SELECTIVE INHIBITOR OF PNEUMOCYSTIS-CARINII DIHYDROFOLATE-REDUCTASE, Proteins, 29(1), 1997, pp. 59-67
Citation: M. Trujillo et al., CONSTRUCTION OF A HOMODIMERIC DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE BIFUNCTIONAL ENZYME, Protein engineering, 10(5), 1997, pp. 567-573
Authors:
SIRAWARAPORN W
SATHITKUL T
SIRAWARAPORN R
YUTHAVONG Y
SANTI DV
Citation: W. Sirawaraporn et al., ANTIFOLATE-RESISTANT MUTANTS OF PLASMODIUM-FALCIPARUM DIHYDROFOLATE-REDUCTASE, Proceedings of the National Academy of Sciences of the United Statesof America, 94(4), 1997, pp. 1124-1129
Authors:
SIRAWARAPORN W
YONGKIETTRAKUL S
SIRAWARAPORN R
YUTHAVONG Y
SANTI DV
Citation: W. Sirawaraporn et al., PLASMODIUM-FALCIPARUM - ASPARAGINE MUTANT AT RESIDUE-108 OF DIHYDROFOLATE-REDUCTASE IS AN OPTIMAL ANTIFOLATE-RESISTANT SINGLE MUTANT, Experimental parasitology, 87(3), 1997, pp. 245-252
Citation: Wd. Huang et Dv. Santi, ACTIVE-SITE GENERAL CATALYSTS ARE NOT NECESSARY FOR SOME PROTON-TRANSFER REACTIONS OF THYMIDYLATE SYNTHASE, Biochemistry, 36(7), 1997, pp. 1869-1873
Citation: Pl. Yu et al., FUNCTIONAL EXPRESSION OF THE DIHYDROFOLATE-REDUCTASE DOMAIN OF LEISHMANIA-MAJOR DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE BIFUNCTIONAL PROTEIN, Protein expression and purification, 8(1), 1996, pp. 23-27
Authors:
AGARWALLA S
GOKHALE RS
SANTI DV
BALARAM P
Citation: S. Agarwalla et al., COVALENT TETHERING OF THE DIMER INTERFACE ANNULS AGGREGATION IN THYMIDYLATE SYNTHASE, Protein science, 5(2), 1996, pp. 270-277
Citation: Xr. Gu et al., INTERACTION OF TRANSFER-RNA (URACIL-5-)-METHYLTRANSFERASE WITH NO(2)URA-TRANSFER-RNA, Nucleic acids research, 24(6), 1996, pp. 1059-1064