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Results: 1-25 |
Results: 25
THROMBIN RECEPTOR (PAR-1) ANTAGONISTS - HETEROCYCLE-BASED PEPTIDOMIMETICS OF THE SFLLR AGONIST MOTIF
Authors: HOEKSTRA WJ HULSHIZER BL MCCOMSEY DF ANDRADEGORDON P KAUFFMAN JA ADDO MF OKSENBERG D SCARBOROUGH RM MARYANOFF BE
Citation: Wj. Hoekstra et al., THROMBIN RECEPTOR (PAR-1) ANTAGONISTS - HETEROCYCLE-BASED PEPTIDOMIMETICS OF THE SFLLR AGONIST MOTIF, Bioorganic & medicinal chemistry letters, 8(13), 1998, pp. 1649-1654
GLYCOPROTEIN IIB-IIIA IN PLATELET-AGGREGATION - AN EMERGING TARGET FOR THE PREVENTION OF ACUTE CORONARY THROMBOTIC OCCLUSIONS
Authors: PHILLIPS DR LAW D SCARBOROUGH RM
Citation: Dr. Phillips et al., GLYCOPROTEIN IIB-IIIA IN PLATELET-AGGREGATION - AN EMERGING TARGET FOR THE PREVENTION OF ACUTE CORONARY THROMBOTIC OCCLUSIONS, Archives of pathology and laboratory medicine, 122(9), 1998, pp. 811-812
DIHYDROISOQUINOLONE RGD MIMICS - EXPLORATION OF THE ASPARTATE ISOSTERE
Authors: FISHER MJ GUNN BP HARMS CS KLINE AD MULLANEY JT SCARBOROUGH RM SKELTON MA UM SL UTTERBACK BG JAKUBOWSKI JA
Citation: Mj. Fisher et al., DIHYDROISOQUINOLONE RGD MIMICS - EXPLORATION OF THE ASPARTATE ISOSTERE, Bioorganic & medicinal chemistry letters, 7(19), 1997, pp. 2537-2542
INHIBITION OF RABBIT DEEP-VEIN THROMBOSIS BY SPECIFIC INHIBITORS OF COAGULATION-FACTOR XA
Authors: WONG AG KU P LIN PH ZHU BY MARLOWE CK SCARBOROUGH RM HOLLENBACH SJ SINHA U
Citation: Ag. Wong et al., INHIBITION OF RABBIT DEEP-VEIN THROMBOSIS BY SPECIFIC INHIBITORS OF COAGULATION-FACTOR XA, Thrombosis and haemostasis, 1997, pp. 1197-1197
DESIGN, SYNTHESIS AND CHARACTERIZATION OF SPECIFIC INHIBITORS OF COAGULATION-FACTOR XA
Authors: GUNN AC WONG PW MARLOWE CK ZHU BY SCARBOROUGH RM
Citation: Ac. Gunn et al., DESIGN, SYNTHESIS AND CHARACTERIZATION OF SPECIFIC INHIBITORS OF COAGULATION-FACTOR XA, Thrombosis and haemostasis, 1997, pp. 1201-1201
FIBRINOGEN RECEPTOR (GPIIB-IIIA) ANTAGONISTS DERIVED FROM 5,6-BICYCLIC TEMPLATES - AMIDINOINDOLES, AMIDINOINDAZOLES, AND AMIDINOBENZOFURANSCONTAINING THE N-ALPHA-SULFONAMIDE CARBOXYLIC-ACID FUNCTION AS POTENTPLATELET-AGGREGATION INHIBITORS
Authors: SU T NAUGHTON MAH SMYTH MS ROSE JW ARFSTEN AE MCCOWAN JR JAKUBOWSKI JA WYSS VL RUTERBORIES KJ SALL DJ SCARBOROUGH RM
Citation: T. Su et al., FIBRINOGEN RECEPTOR (GPIIB-IIIA) ANTAGONISTS DERIVED FROM 5,6-BICYCLIC TEMPLATES - AMIDINOINDOLES, AMIDINOINDAZOLES, AND AMIDINOBENZOFURANSCONTAINING THE N-ALPHA-SULFONAMIDE CARBOXYLIC-ACID FUNCTION AS POTENTPLATELET-AGGREGATION INHIBITORS, Journal of medicinal chemistry, 40(26), 1997, pp. 4308-4318
USE OF CONFORMATIONALLY RESTRICTED BENZAMIDINES AS ARGININE SURROGATES IN THE DESIGN OF PLATELET GPIIB-IIIA RECEPTOR ANTAGONISTS
Authors: SALL DJ ARFSTEN AE BASTIAN JA DENNEY ML HARMS CS MCCOWAN JR MORIN JM ROSE JW SCARBOROUGH RM SMYTH MS UM SL UTTERBACK BG VASILEFF RT WIKEL JH WYSS VL JAKUBOWSKI JA
Citation: Dj. Sall et al., USE OF CONFORMATIONALLY RESTRICTED BENZAMIDINES AS ARGININE SURROGATES IN THE DESIGN OF PLATELET GPIIB-IIIA RECEPTOR ANTAGONISTS, Journal of medicinal chemistry, 40(18), 1997, pp. 2843-2857
NONPEPTIDE RGD SURROGATES WHICH MIMIC A GLY-ASP BETA-TURN - POTENT ANTAGONISTS OF PLATELET GLYCOPROTEIN IIB-IIIA
Authors: FISHER MJ GUNN B HARMS CS KLINE AD MULLANEY JT NUNES A SCARBOROUGH RM ARFSTEN AE SKELTON MA UM SL UTTERBACK BG JAKUBOWSKI JA
Citation: Mj. Fisher et al., NONPEPTIDE RGD SURROGATES WHICH MIMIC A GLY-ASP BETA-TURN - POTENT ANTAGONISTS OF PLATELET GLYCOPROTEIN IIB-IIIA, Journal of medicinal chemistry, 40(13), 1997, pp. 2085-2101
FACTOR XA ANTAGONIST (C921-78) INHIBITS ARTERIAL THROMBOSIS WITHOUT IMPAIRMENT OF EXTRAVASCULAR HEMOSTATIS
Authors: BENEDICT CR TODD J ZHU BY SCARBOROUGH RM SINHA U
Citation: Cr. Benedict et al., FACTOR XA ANTAGONIST (C921-78) INHIBITS ARTERIAL THROMBOSIS WITHOUT IMPAIRMENT OF EXTRAVASCULAR HEMOSTATIS, Circulation, 96(8), 1997, pp. 220-220
EFFECT OF CA2-IIIA INTERACTIONS WITH INTEGRILIN - ENHANCED GP IIB-IIIA BINDING AND INHIBITION OF PLATELET-AGGREGATION BY REDUCTIONS IN THE CONCENTRATION OF IONIZED CALCIUM IN PLASMA ANTICOAGULATED WITH CITRATE( ON GP IIB)
Authors: PHILLIPS DR TENG W ARFSTEN A NANNIZZIALAIMO L WHITE MM LONGHURST C SHATTIL SJ RANDOLPH A JAKUBOWSKI JA JENNINGS LK SCARBOROUGH RM
Citation: Dr. Phillips et al., EFFECT OF CA2-IIIA INTERACTIONS WITH INTEGRILIN - ENHANCED GP IIB-IIIA BINDING AND INHIBITION OF PLATELET-AGGREGATION BY REDUCTIONS IN THE CONCENTRATION OF IONIZED CALCIUM IN PLASMA ANTICOAGULATED WITH CITRATE( ON GP IIB), Circulation, 96(5), 1997, pp. 1488-1494
CLINICAL-PHARMACOLOGY OF EPTIFIBATIDE
Authors: PHILLIPS DR SCARBOROUGH RM
Citation: Dr. Phillips et Rm. Scarborough, CLINICAL-PHARMACOLOGY OF EPTIFIBATIDE, The American journal of cardiology, 80(4A), 1997, pp. 11-20
PLATELET GLYCOPROTEIN IIB-IIIA RECEPTOR (GPIIB-IIIA) ANTAGONISTS DERIVED FROM AMIDINOINDOLES
Authors: SALL DJ ARFSTEN AE BERRY DR DENNEY ML HARMS CS MCCOWAN JR RAY JK SCARBOROUGH RM UM SL UTTERBACK BG JAKUBOWSKI JA
Citation: Dj. Sall et al., PLATELET GLYCOPROTEIN IIB-IIIA RECEPTOR (GPIIB-IIIA) ANTAGONISTS DERIVED FROM AMIDINOINDOLES, Bioorganic & medicinal chemistry letters, 6(1), 1996, pp. 81-86
LIGAND CROSS-REACTIVITY WITHIN THE PROTEASE-ACTIVATED RECEPTOR FAMILY
Authors: BLACKHART BD EMILSSON K NGUYEN D TENG W MARTELLI AJ NYSTEDT S SUNDELIN J SCARBOROUGH RM
Citation: Bd. Blackhart et al., LIGAND CROSS-REACTIVITY WITHIN THE PROTEASE-ACTIVATED RECEPTOR FAMILY, The Journal of biological chemistry, 271(28), 1996, pp. 16466-16471
EVIDENCE FOR A NOVEL THROMBIN RECEPTOR ON RAT PLATELETS
Authors: BONE BG DESHPANDE US RUNGE MS TAI A TENG W SCARBOROUGH RM CONLEY PB BABA D REYNOLDS EE RAMAKRISHNAN V
Citation: Bg. Bone et al., EVIDENCE FOR A NOVEL THROMBIN RECEPTOR ON RAT PLATELETS, Blood, 88(10), 1996, pp. 2482-2482
BINDING OF A NOVEL 50-KILODALTON ALBOAGGREGIN FROM TRIMERESURUS-ALBOLABRIS AND RELATED VIPER VENOM PROTEINS TO THE PLATELET MEMBRANE GLYCOPROTEIN IB-IX-V COMPLEX - EFFECT ON PLATELET-AGGREGATION AND GLYCOPROTEIN IB-MEDIATED PLATELET ACTIVATION
Authors: ANDREWS RK KROLL MH WARD CM ROSE JW SCARBOROUGH RM SMITH AI LOPEZ JA BERNDT MC
Citation: Rk. Andrews et al., BINDING OF A NOVEL 50-KILODALTON ALBOAGGREGIN FROM TRIMERESURUS-ALBOLABRIS AND RELATED VIPER VENOM PROTEINS TO THE PLATELET MEMBRANE GLYCOPROTEIN IB-IX-V COMPLEX - EFFECT ON PLATELET-AGGREGATION AND GLYCOPROTEIN IB-MEDIATED PLATELET ACTIVATION, Biochemistry, 35(38), 1996, pp. 12629-12639
EVIDENCE FOR THE PRESENCE OF A PROTEASE ACTIVATED RECEPTOR DISTINCT FROM THE THROMBIN RECEPTOR IN HUMAN KERATINOCYTES
Authors: ANDRADEGORDON P SANTULLI RJ DERIAN CK DARROW AL TOMKO KA ECKARDT AJ ARFSTEN AE TENG W NAUGHTON MA SCARBOROUGH RM
Citation: P. Andradegordon et al., EVIDENCE FOR THE PRESENCE OF A PROTEASE ACTIVATED RECEPTOR DISTINCT FROM THE THROMBIN RECEPTOR IN HUMAN KERATINOCYTES, Thrombosis and haemostasis, 73(6), 1995, pp. 924-924
CROSS-REACTIVITY OF THROMBIN RECEPTOR AND PAR-2 AGONIST PEPTIDES - ISTHERE A SIMPLE EXPLANATION FOR ALLEGED THROMBIN RECEPTOR SUBTYPES
Authors: BLACKHART BD TENG W NAUGHTON MA NYSTEDT S EMILSSON K SUNDELIN J SCARBOROUGH RM
Citation: Bd. Blackhart et al., CROSS-REACTIVITY OF THROMBIN RECEPTOR AND PAR-2 AGONIST PEPTIDES - ISTHERE A SIMPLE EXPLANATION FOR ALLEGED THROMBIN RECEPTOR SUBTYPES, Thrombosis and haemostasis, 73(6), 1995, pp. 928-928
EVIDENCE FOR THE PRESENCE OF A PROTEASE-ACTIVATED RECEPTOR DISTINCT FROM THE THROMBIN RECEPTOR IN HUMAN KERATINOCYTES
Authors: SANTULLI RJ DERIAN CK DARROW AL TOMKO KA ECKARDT AJ SEIBERG M SCARBOROUGH RM ANDRADEGORDON P
Citation: Rj. Santulli et al., EVIDENCE FOR THE PRESENCE OF A PROTEASE-ACTIVATED RECEPTOR DISTINCT FROM THE THROMBIN RECEPTOR IN HUMAN KERATINOCYTES, Proceedings of the National Academy of Sciences of the United Statesof America, 92(20), 1995, pp. 9151-9155
THE ANION-BINDING EXOSITE IS CRITICAL FOR THE HIGH-AFFINITY BINDING OF THROMBIN TO THE HUMAN THROMBIN RECEPTOR
Authors: BLACKHART BD CUENCO G TODA T SCARBOROUGH RM WOLF DL RAMAKRISHNAN V
Citation: Bd. Blackhart et al., THE ANION-BINDING EXOSITE IS CRITICAL FOR THE HIGH-AFFINITY BINDING OF THROMBIN TO THE HUMAN THROMBIN RECEPTOR, Growth factors, 11(1), 1994, pp. 17-28
INHIBITION OF IN-VIVO THROMBUS FORMATION IN AN ARTERIAL-STENOSIS MODEL
Authors: HANSON SR MARKOU C LINDAHL AK KU DN SCARBOROUGH RM PHILLIPS DR GORECKI M PINET A GARFINKEL L KELLY AB HARKER LA
Citation: Sr. Hanson et al., INHIBITION OF IN-VIVO THROMBUS FORMATION IN AN ARTERIAL-STENOSIS MODEL, Thrombosis and haemostasis, 69(6), 1993, pp. 540-540
ANTITHROMBOTIC EFFECT OF A THROMBIN RECEPTOR ANTAGONIST PEPTIDE IN BABOONS
Authors: LINDAHL AK SCARBOROUGH RM NAUGHTON MA HARKER LA HANSON SR
Citation: Ak. Lindahl et al., ANTITHROMBOTIC EFFECT OF A THROMBIN RECEPTOR ANTAGONIST PEPTIDE IN BABOONS, Thrombosis and haemostasis, 69(6), 1993, pp. 1196-1196
THE ANION-BINDING EXOSITE IS CRITICAL FOR THE HIGH-AFFINITY BINDING OF THROMBIN TO THE THROMBIN RECEPTOR
Authors: RAMAKRISHNAN V TODA T CUENCO G SCARBOROUGH RM WOLF DL BLACKHART BD
Citation: V. Ramakrishnan et al., THE ANION-BINDING EXOSITE IS CRITICAL FOR THE HIGH-AFFINITY BINDING OF THROMBIN TO THE THROMBIN RECEPTOR, Circulation, 88(4), 1993, pp. 127-127
IMMUNOLOGICAL ANALYSIS OF THE CLONED PLATELET THROMBIN RECEPTOR ACTIVATION MECHANISM - EVIDENCE SUPPORTING RECEPTOR CLEAVAGE, RELEASE OF THE N-TERMINAL PEPTIDE, AND INSERTION OF THE TETHERED LIGAND INTO A PROTECTED ENVIRONMENT
Authors: NORTON KJ SCARBOROUGH RM KUTOK JL ESCOBEDO MA NANNIZZI L COLLER BS
Citation: Kj. Norton et al., IMMUNOLOGICAL ANALYSIS OF THE CLONED PLATELET THROMBIN RECEPTOR ACTIVATION MECHANISM - EVIDENCE SUPPORTING RECEPTOR CLEAVAGE, RELEASE OF THE N-TERMINAL PEPTIDE, AND INSERTION OF THE TETHERED LIGAND INTO A PROTECTED ENVIRONMENT, Blood, 82(7), 1993, pp. 2125-2136
ENDOCYTOSIS OF FIBRINOGEN INTO MEGAKARYOCYTE AND PLATELET ALPHA-GRANULES IS MEDIATED BY ALPHA(IIB)BETA(3) (GLYCOPROTEIN-IIB-IIIA)
Authors: HANDAGAMA P SCARBOROUGH RM SHUMAN MA BAINTON DF
Citation: P. Handagama et al., ENDOCYTOSIS OF FIBRINOGEN INTO MEGAKARYOCYTE AND PLATELET ALPHA-GRANULES IS MEDIATED BY ALPHA(IIB)BETA(3) (GLYCOPROTEIN-IIB-IIIA), Blood, 82(1), 1993, pp. 135-138
THROMBIN RECEPTOR STRUCTURE AND FUNCTION
Authors: COUGHLIN SR SCARBOROUGH RM VU TKH HUNG DT
Citation: Sr. Coughlin et al., THROMBIN RECEPTOR STRUCTURE AND FUNCTION, Cold Spring Harbor Symposia on Quantitative Biology, 57, 1992, pp. 149-154
Risultati: 1-25 |