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Results: 1-25 | 26-36
Results: 1-25/36
SIMULTANEOUS VS SEQUENTIAL INITIATION OF THERAPY WITH INDINAVIR, ZIDOVUDINE, AND LAMIVUDINE FOR HIV-1 INFECTION - 100-WEEK FOLLOW-UP
Authors: GULICK RM MELLORS JW HAVLIR D ERON JJ GONZALEZ C MCMAHON D JONAS L MEIBOHM A HOLDER D SCHLEIF WA CONDRA JH EMINI EA ISAACS R CHODAKEWITZ JA RICHMAN DD
Citation: Rm. Gulick et al., SIMULTANEOUS VS SEQUENTIAL INITIATION OF THERAPY WITH INDINAVIR, ZIDOVUDINE, AND LAMIVUDINE FOR HIV-1 INFECTION - 100-WEEK FOLLOW-UP, JAMA, the journal of the American Medical Association, 280(1), 1998, pp. 35-41
CRIXIVAN(R) - A POTENT INHIBITOR OF HIV-1 PROTEASE IN-VIVO
Authors: HUFF JR VACCA JP DORSEY BD EMINI EA CONDRA JH SCHLEIF WA MASSARI FE DEUTSCH PJ CHODAKEWITZ J KUO LC CHEN Z
Citation: Jr. Huff et al., CRIXIVAN(R) - A POTENT INHIBITOR OF HIV-1 PROTEASE IN-VIVO, The FASEB journal, 11(9), 1997, pp. 23-23
AN ORALLY BIOAVAILABLE PYRROLINONE INHIBITOR OF HIV-1 PROTEASE - COMPUTATIONAL ANALYSIS AND X-RAY CRYSTAL-STRUCTURE OF THE ENZYME COMPLEX
Authors: SMITH AB HIRSCHMANN R PASTERNAK A YAO WQ SPRENGELER PA HOLLOWAY MK KUO LC CHEN ZG DARKE PL SCHLEIF WA
Citation: Ab. Smith et al., AN ORALLY BIOAVAILABLE PYRROLINONE INHIBITOR OF HIV-1 PROTEASE - COMPUTATIONAL ANALYSIS AND X-RAY CRYSTAL-STRUCTURE OF THE ENZYME COMPLEX, Journal of medicinal chemistry, 40(16), 1997, pp. 2440-2444
GENETIC CORRELATES OF IN-VIVO VIRAL RESISTANCE TO INDINAVIR, A HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASE INHIBITOR
Authors: CONDRA JH HOLDER DJ SCHLEIF WA BLAHY OM DANOVICH RM GABRYELSKI LJ GRAHAM DJ LAIRD D QUINTERO JC RHODES A ROBBINS HL ROTH E SHIVAPRAKASH M YANG T CHODAKEWITZ JA DEUTSCH PJ LEAVITT RY MASSARI FE MELLORS JW SQUIRES KE STEIGBIGEL RT TEPPLER H EMINI EA
Citation: Jh. Condra et al., GENETIC CORRELATES OF IN-VIVO VIRAL RESISTANCE TO INDINAVIR, A HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASE INHIBITOR, Journal of virology, 70(12), 1996, pp. 8270-8276
THE CONSEQUENCE OF PASSIVE ADMINISTRATION OF AN ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 NEUTRALIZING MONOCLONAL-ANTIBODY BEFORE CHALLENGE OF CHIMPANZEES WITH A PRIMARY VIRUS ISOLATE
Authors: CONLEY AJ KESSLER JA BOOTS LJ MCKENNA PM SCHLEIF WA EMINI EA MARK GE KATINGER H COBB EK LUNCEFORD SM ROUSE SR MURTHY KK
Citation: Aj. Conley et al., THE CONSEQUENCE OF PASSIVE ADMINISTRATION OF AN ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 NEUTRALIZING MONOCLONAL-ANTIBODY BEFORE CHALLENGE OF CHIMPANZEES WITH A PRIMARY VIRUS ISOLATE, Journal of virology, 70(10), 1996, pp. 6751-6758
NONPEPTIDAL P-2 LIGANDS FOR HIV PROTEASE INHIBITORS - STRUCTURE-BASEDDESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION
Authors: GHOSH AK KINCAID JF WALTERS DE CHEN Y CHAUDHURI NC THOMPSON WJ CULBERSON C FITZGERALD PMD LEE HY MCKEE SP MUNSON PM DUONG TT DARKE PL ZUGAY JA SCHLEIF WA AXEL MG LIN J HUFF JR
Citation: Ak. Ghosh et al., NONPEPTIDAL P-2 LIGANDS FOR HIV PROTEASE INHIBITORS - STRUCTURE-BASEDDESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION, Journal of medicinal chemistry, 39(17), 1996, pp. 3278-3290
CORRELATION BETWEEN GENOTYPIC EVIDENCE OF HIV-1 RESISTANCE TO THE PROTEASE INHIBITOR MK-639 AND LOSS OF ANTIRETROVIRAL EFFECT IN TREATED PATIENTS
Authors: MELLORS JW MCMAHON DK CHODAKEWITZ JA SCHLEIF WA EMINI EA CONDRA JH
Citation: Jw. Mellors et al., CORRELATION BETWEEN GENOTYPIC EVIDENCE OF HIV-1 RESISTANCE TO THE PROTEASE INHIBITOR MK-639 AND LOSS OF ANTIRETROVIRAL EFFECT IN TREATED PATIENTS, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 71-71
DYNAMICS OF ACQUIRED HIV-1 CLINICAL RESISTANCE TO THE PROTEASE INHIBITOR MK-639
Authors: CONDRA JH SCHLEIF WA BLAHY OM GABRYELSKI LJ GRAHAM DJ QUINTERO JC RHODES A ROBBINS HL ROTH E SHIVAPRAKASH M TITUS D YANG T ZHANG J CHODAKEWITZ JA DEUTSCH PJ EMINI EA
Citation: Jh. Condra et al., DYNAMICS OF ACQUIRED HIV-1 CLINICAL RESISTANCE TO THE PROTEASE INHIBITOR MK-639, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 72-72
EVIDENCE FOR THE EXISTENCE OF LONG-LIVED GENETIC RESERVOIRS OF HIV-1 IN INFECTED PATIENTS
Authors: CONDRA JH SCHLEIF WA BLAHY OM GABRYELSKI LJ GRAHAM DJ QUINTERO JC RHODES A ROBBINS HL ROTH E SHIVAPRAKASH M TITUS D YANG T ZHANG J DEUTSCH PJ SQUIRES KE EMINI EA
Citation: Jh. Condra et al., EVIDENCE FOR THE EXISTENCE OF LONG-LIVED GENETIC RESERVOIRS OF HIV-1 IN INFECTED PATIENTS, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 82-82
SYNTHESIS AND EVALUATION OF PYRIDYL ANALOGS OF L-735,524 - POTENT HIV-1 PROTEASE INHIBITORS (VOL 4, PG 2769, 1994)
Authors: DORSEY BD MCDANIEL SL LEVIN RB VACCA JP DARKE PL ZUGAY JA EMINI EA SCHLEIF WA LIN JH CHEN IW HOLLOWAY MK ANDERSON PS HUFF JR
Citation: Bd. Dorsey et al., SYNTHESIS AND EVALUATION OF PYRIDYL ANALOGS OF L-735,524 - POTENT HIV-1 PROTEASE INHIBITORS (VOL 4, PG 2769, 1994), Bioorganic & medicinal chemistry letters, 5(7), 1995, pp. 773-773
2-HETEROCYCLIC INDOLE-3-SULFONES AS INHIBITORS OF HIV-1 REVERSE-TRANSCRIPTASE
Authors: YOUNG SD AMBLARD MC BRITCHER SF GREY VE TRAN LO LUMMA WC HUFF JR SCHLEIF WA EMINI EE OBRIEN JA PETTIBONE DJ
Citation: Sd. Young et al., 2-HETEROCYCLIC INDOLE-3-SULFONES AS INHIBITORS OF HIV-1 REVERSE-TRANSCRIPTASE, Bioorganic & medicinal chemistry letters, 5(5), 1995, pp. 491-496
L-743,726 (DMP-266) - A NOVEL, HIGHLY POTENT NONNUCLEOSIDE INHIBITOR OF THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE
Authors: YOUNG SD BRITCHER SF TRAN LO PAYNE LS LUMMA WC LYLE TA HUFF JR ANDERSON PS OLSEN DB CARROLL SS PETTIBONE DJ OBRIEN JA BALL RG BALANI SK LIN JH CHEN IW SCHLEIF WA SARDANA VV LONG WJ BYRNES VW EMINI EA
Citation: Sd. Young et al., L-743,726 (DMP-266) - A NOVEL, HIGHLY POTENT NONNUCLEOSIDE INHIBITOR OF THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE, Antimicrobial agents and chemotherapy, 39(12), 1995, pp. 2602-2605
IN-VIVO EMERGENCE OF HIV-1 VARIANTS RESISTANT TO MULTIPLE PROTEASE INHIBITORS
Authors: CONDRA JH SCHLEIF WA BLAHY OM GABRYELSKI LJ GRAHAM DJ QUINTERO JC RHODES A ROBBINS HL ROTH E SHIVAPRAKASH M TITUS D YANG T TEPPLER H SQUIRES KE DEUTSCH PJ EMINI EA
Citation: Jh. Condra et al., IN-VIVO EMERGENCE OF HIV-1 VARIANTS RESISTANT TO MULTIPLE PROTEASE INHIBITORS, Nature, 374(6522), 1995, pp. 569-571
COMBINATION THERAPY WITH ZIDOVUDINE PREVENTS SELECTION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 VARIANTS EXPRESSING HIGH-LEVEL RESISTANCE TO L-697,661, A NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR
Authors: STASZEWSKI S MASSARI FE KOBER A GOHLER R DURR S ANDERSON KW SCHNEIDER CL WATERBURY JA BAKSHI KK TAYLOR VI HILDEBRAND CS KREISL C HOFFSTEDT B SCHLEIF WA VONBRIESEN H RUBSAMENWAIGMANN H CALANDRA GB RYAN JL STILLE W EMINI EA BYRNES VW
Citation: S. Staszewski et al., COMBINATION THERAPY WITH ZIDOVUDINE PREVENTS SELECTION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 VARIANTS EXPRESSING HIGH-LEVEL RESISTANCE TO L-697,661, A NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR, The Journal of infectious diseases, 171(5), 1995, pp. 1159-1165
PYRROLINONE-BASED HIV PROTEASE INHIBITORS - DESIGN, SYNTHESIS, AND ANTIVIRAL ACTIVITY - EVIDENCE FOR IMPROVED TRANSPORT
Authors: SMITH AB HIRSCHMANN R PASTERNAK A GUZMAN MC YOKOYAMA A SPRENGELER PA DARKE PL EMINI EA SCHLEIF WA
Citation: Ab. Smith et al., PYRROLINONE-BASED HIV PROTEASE INHIBITORS - DESIGN, SYNTHESIS, AND ANTIVIRAL ACTIVITY - EVIDENCE FOR IMPROVED TRANSPORT, Journal of the American Chemical Society, 117(45), 1995, pp. 11113-11123
SYNTHESIS AND EVALUATION OF PYRIDYL ANALOGS OF L-735,524 - POTENT HIV-1 PROTEASE INHIBITORS
Authors: DORSEY BD MCDANIEL SL LEVIN RB VACCA JP DARKE PL ZUGAY JA EMINI EA SCHLEIF WA LIN JH CHEN IW HOLLOWAY MK ANDERSON PS HUFF JR
Citation: Bd. Dorsey et al., SYNTHESIS AND EVALUATION OF PYRIDYL ANALOGS OF L-735,524 - POTENT HIV-1 PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 4(23), 1994, pp. 2769-2774
A BROADLY REACTIVE HUMAN ANTI-V3 MONOCLONAL-ANTIBODY EFFECTIVELY NEUTRALIZES PRIMARY HIV-1 ISOLATES
Authors: GORNY M WILLIAMS C ZOLLAPAZNER S OSSORIO M BANSAL G KOENIG S CONLEY AJ KESSLER JA BOOTS LJ LINEBERGER D SCHLEIF WA EMINI EA
Citation: M. Gorny et al., A BROADLY REACTIVE HUMAN ANTI-V3 MONOCLONAL-ANTIBODY EFFECTIVELY NEUTRALIZES PRIMARY HIV-1 ISOLATES, AIDS research and human retroviruses, 10, 1994, pp. 190000034-190000034
ATTEMPTED PROPHYLAXIS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION IN CHIMPANZEES WITH A NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR
Authors: SCHLEIF WA MURTHY KK SARDANA VV SCHNEIDER CL BYRNES VW COBB KE ROTH E WOLFGANG JA HOFFMAN JM SMITH AM GELOTTE KM EMINI EA
Citation: Wa. Schleif et al., ATTEMPTED PROPHYLAXIS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION IN CHIMPANZEES WITH A NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR, AIDS research and human retroviruses, 10(1), 1994, pp. 107-110
THE DESIGN AND SYNTHESIS OF ORALLY BIOAVAILABLE HIV-1 PROTEASE INHIBITORS
Authors: HUFF JR VACCA JP DORSEY BD THOMPSON WJ GHOSH AK HUNGATE RW LEE HY DARKE PL EMINI EA SCHLEIF WA LIN JH CHEN IW HOLLOWAY MK ANDERSON PS
Citation: Jr. Huff et al., THE DESIGN AND SYNTHESIS OF ORALLY BIOAVAILABLE HIV-1 PROTEASE INHIBITORS, Journal of cellular biochemistry, 1994, pp. 130-130
MUTATIONS IN HIV-1 PROTEASE RESIDUES AFFECTING SUSCEPTIBILITY TO L-735,524
Authors: CONDRA JH BLAHY OM BUSH BL CULBERSON C GOTLIB L GRAHAM DJ GRAHAM PL HOLLOWAY MK LAFEMINA RL QUINTERO JC RHODES A ROTH E SARDANA VV SCHNEIDER CL SCHLABACH AJ SCHLEIF WA TITUS DL WOLANSKI BS WOLFGANG JA EMINI EA
Citation: Jh. Condra et al., MUTATIONS IN HIV-1 PROTEASE RESIDUES AFFECTING SUSCEPTIBILITY TO L-735,524, Journal of cellular biochemistry, 1994, pp. 166-166
THE GENETIC AND FUNCTIONAL BASIS OF HIV-1 RESISTANCE TO NONNUCLEOSIDEREVERSE-TRANSCRIPTASE INHIBITORS
Authors: EMINI EA BYRNES VW CONDRA JH SCHLEIF WA SARDANA VV
Citation: Ea. Emini et al., THE GENETIC AND FUNCTIONAL BASIS OF HIV-1 RESISTANCE TO NONNUCLEOSIDEREVERSE-TRANSCRIPTASE INHIBITORS, Archives of virology, 1994, pp. 11-17
SUSCEPTIBILITIES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ENZYME AND VIRAL VARIANTS EXPRESSING MULTIPLE RESISTANCE-ENGENDERING AMINO-ACID SUBSTITUTIONS TO REVERSE-TRANSCRIPTASE INHIBITORS
Authors: BYRNES VW EMINI EA SCHLEIF WA CONDRA JH SCHNEIDER CL LONG WJ WOLFGANG JA GRAHAM DJ GOTLIB L SCHLABACH AJ WOLANSKI BS BLAHY OM QUINTERO JC RHODES A ROTH E TITUS DL SARDANA VV
Citation: Vw. Byrnes et al., SUSCEPTIBILITIES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ENZYME AND VIRAL VARIANTS EXPRESSING MULTIPLE RESISTANCE-ENGENDERING AMINO-ACID SUBSTITUTIONS TO REVERSE-TRANSCRIPTASE INHIBITORS, Antimicrobial agents and chemotherapy, 38(6), 1994, pp. 1404-1407
L-735,524 - AN ORALLY BIOAVAILABLE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASE INHIBITOR
Authors: VACCA JP DORSEY BD SCHLEIF WA LEVIN RB MCDANIEL SL DARKE PL ZUGAY J QUINTERO JC BLAHY OM ROTH E SARDANA VV SCHLABACH AJ GRAHAM PI CONDRA JH GOTLIB L HOLLOWAY MK LIN J CHEN IW VASTAG K OSTOVIC D ANDERSON PS EMINI EA HUFF JR
Citation: Jp. Vacca et al., L-735,524 - AN ORALLY BIOAVAILABLE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASE INHIBITOR, Proceedings of the National Academy of Sciences of the United Statesof America, 91(9), 1994, pp. 4096-4100
THE DEVELOPMENT OF CYCLIC SULFOLANES AS NOVEL AND HIGH-AFFINITY P(2) LIGANDS FOR HIV-1 PROTEASE INHIBITORS
Authors: GHOSH AK LEE HY THOMPSON WJ CULBERSON C HOLLOWAY MK MCKEE SP MUNSON PM DUONG TT SMITH AM DARKE PL ZUGAY JA EMINI EA SCHLEIF WA HUFF JR ANDERSON PS
Citation: Ak. Ghosh et al., THE DEVELOPMENT OF CYCLIC SULFOLANES AS NOVEL AND HIGH-AFFINITY P(2) LIGANDS FOR HIV-1 PROTEASE INHIBITORS, Journal of medicinal chemistry, 37(8), 1994, pp. 1177-1188
L-735,524 - THE DESIGN OF A POTENT AND ORALLY BIOAVAILABLE HIV PROTEASE INHIBITOR
Authors: DORSEY BD LEVIN RB MCDANIEL SL VACCA JP GUARE JP DARKE PL ZUGAY JA EMINI EA SCHLEIF WA QUINTERO JC LIN JH CHEN IW HOLLOWAY MK FITZGERALD PMD AXEL MG OSTOVIC D ANDERSON PS HUFF JR
Citation: Bd. Dorsey et al., L-735,524 - THE DESIGN OF A POTENT AND ORALLY BIOAVAILABLE HIV PROTEASE INHIBITOR, Journal of medicinal chemistry, 37(21), 1994, pp. 3443-3451
Risultati: 1-25 | 26-36