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Results: 1-25 | 26-36
Results: 1-25/36
THE P53 TUMOR-SUPPRESSOR TARGETS A NOVEL REGULATOR OF G-PROTEIN SIGNALING
Authors: BUCKBINDER L VELASCOMIGUEL S CHEN Y XU NZ TALBOTT R GELBERT L GAO JZ SEIZINGER BR GUTKIND JS KLEY N
Citation: L. Buckbinder et al., THE P53 TUMOR-SUPPRESSOR TARGETS A NOVEL REGULATOR OF G-PROTEIN SIGNALING, Proceedings of the National Academy of Sciences of the United Statesof America, 94(15), 1997, pp. 7868-7872
A KINDRED WITH A VARIANT OF MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 DEMONSTRATING FREQUENT EXPRESSION OF PITUITARY-TUMORS BUT NOT LINKED TO THEMULTIPLE ENDOCRINE NEOPLASIA TYPE-1 LOCUS AT CHROMOSOME REGION 11Q13
Authors: STOCK JL WARTH MR TEH BT CODERRE JA OVERDORF JH BAUMANN G HINTZ RL HARTMAN ML SEIZINGER BR LARSSON C ARONIN N
Citation: Jl. Stock et al., A KINDRED WITH A VARIANT OF MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 DEMONSTRATING FREQUENT EXPRESSION OF PITUITARY-TUMORS BUT NOT LINKED TO THEMULTIPLE ENDOCRINE NEOPLASIA TYPE-1 LOCUS AT CHROMOSOME REGION 11Q13, The Journal of clinical endocrinology and metabolism, 82(2), 1997, pp. 486-492
DEVELOPMENT OF HIGHLY POTENT INHIBITORS OF RAS FARNESYLTRANSFERASE POSSESSING CELLULAR AND IN-VIVO ACTIVITY
Authors: LEFTHERIS K KLINE T VITE GD CHO YH BHIDE RS PATEL DV PATEL MM SCHMIDT RJ WELLER HN ANDAHAZY ML CARBONI JM GULLOBROWN JL LEE FYF RICCA C ROSE WC YAN N BARBACID M HUNT JT MEYERS CA SEIZINGER BR ZAHLER R MANNE V
Citation: K. Leftheris et al., DEVELOPMENT OF HIGHLY POTENT INHIBITORS OF RAS FARNESYLTRANSFERASE POSSESSING CELLULAR AND IN-VIVO ACTIVITY, Journal of medicinal chemistry, 39(1), 1996, pp. 224-236
CHROMOSOME-17 ALLELIC LOSS AND NF1-GRD MUTATIONS DO NOT PLAY A SIGNIFICANT ROLE AS MOLECULAR MECHANISMS LEADING TO MELANOMA TUMORIGENESIS
Authors: GOMEZ L RUBIO MP MARTIN MT VAZQUEZ JJ IDOATE M PASTORFIDE G PESTANA A SEIZINGER BR BARNHILL RL CASTRESANA JS
Citation: L. Gomez et al., CHROMOSOME-17 ALLELIC LOSS AND NF1-GRD MUTATIONS DO NOT PLAY A SIGNIFICANT ROLE AS MOLECULAR MECHANISMS LEADING TO MELANOMA TUMORIGENESIS, Journal of investigative dermatology, 106(3), 1996, pp. 432-436
BISUBSTRATE INHIBITORS OF FARNESYLTRANSFERASE - A NOVEL CLASS OF SPECIFIC INHIBITORS OF RAS TRANSFORMED-CELLS
Authors: MANNE V YAN N CARBONI JM TUOMARI AV RICCA CS BROWN JG ANDAHAZY ML SCHMIDT RJ PATEL D ZAHLER R WEINMANN R DER CJ COX AD HUNT JT GORDON EM BARBACID M SEIZINGER BR
Citation: V. Manne et al., BISUBSTRATE INHIBITORS OF FARNESYLTRANSFERASE - A NOVEL CLASS OF SPECIFIC INHIBITORS OF RAS TRANSFORMED-CELLS, Oncogene, 10(9), 1995, pp. 1763-1779
CLONING AND CHARACTERIZATION OF MN1, A GENE FROM CHROMOSOME 22Q11, WHICH IS DISRUPTED BY A BALANCED TRANSLOCATION IN A MENINGIOMA
Authors: DEPREZ RHL RIEGMAN PHJ GROEN NA WARRINGA UL VANBIEZEN NA MOLIJN AC BOOTSMA D DEJONG PJ MENON AG KLEY NA SEIZINGER BR ZWARTHOFF EC
Citation: Rhl. Deprez et al., CLONING AND CHARACTERIZATION OF MN1, A GENE FROM CHROMOSOME 22Q11, WHICH IS DISRUPTED BY A BALANCED TRANSLOCATION IN A MENINGIOMA, Oncogene, 10(8), 1995, pp. 1521-1528
FARNESYLTRANSFERASE INHIBITORS ARE INHIBITORS OF RAS BUT NOT R-RAS2 TC21, TRANSFORMATION/
Authors: CARBONI JM YAN N COX AD BUSTELO X GRAHAM SM LYNCH MJ WEINMANN R SEIZINGER BR DER CJ BARBACID M MANNE V
Citation: Jm. Carboni et al., FARNESYLTRANSFERASE INHIBITORS ARE INHIBITORS OF RAS BUT NOT R-RAS2 TC21, TRANSFORMATION/, Oncogene, 10(10), 1995, pp. 1905-1913
NEUROFIBROMATOSIS TYPE-2 AND VON HIPPEL-LINDAU DISEASE - FROM GENE CLONING TO FUNCTION
Authors: KLEY N WHALEY J SEIZINGER BR
Citation: N. Kley et al., NEUROFIBROMATOSIS TYPE-2 AND VON HIPPEL-LINDAU DISEASE - FROM GENE CLONING TO FUNCTION, Glia, 15(3), 1995, pp. 297-307
RAS FARNESYLATION AS A TARGET FOR NOVEL ANTITUMOR AGENTS - POTENT ANDSELECTIVE FARNESYL DIPHOSPHATE ANALOG INHIBITORS OF FARNESYLTRANSFERASE
Authors: MANNE V RICCA CS BROWN JG TUOMARI AV YAN N PATEL D SCHMIDT R LYNCH MJ CIOSEK CP CARBONI JM ROBINSON S GORDON EM BARBACID M SEIZINGER BR BILLER SA
Citation: V. Manne et al., RAS FARNESYLATION AS A TARGET FOR NOVEL ANTITUMOR AGENTS - POTENT ANDSELECTIVE FARNESYL DIPHOSPHATE ANALOG INHIBITORS OF FARNESYLTRANSFERASE, Drug development research, 34(2), 1995, pp. 121-137
THE NEUROFIBROMATOSIS-2 (NF2) TUMOR-SUPPRESSOR GENE - IMPLICATIONS BEYOND THE HEREDITARY TUMOR SYNDROME
Authors: KLEY N SEIZINGER BR
Citation: N. Kley et Br. Seizinger, THE NEUROFIBROMATOSIS-2 (NF2) TUMOR-SUPPRESSOR GENE - IMPLICATIONS BEYOND THE HEREDITARY TUMOR SYNDROME, Cancer surveys, 25, 1995, pp. 207-218
INDUCTION OF THE GROWTH INHIBITOR IGF-BINDING PROTEIN-3 BY P53
Authors: BUCKBINDER L TALBOTT R VELASCOMIGUEL S TAKENAKA I FAHA B SEIZINGER BR KLEY N
Citation: L. Buckbinder et al., INDUCTION OF THE GROWTH INHIBITOR IGF-BINDING PROTEIN-3 BY P53, Nature, 377(6550), 1995, pp. 646-649
PHOSPHINYL ACID-BASED BISUBSTRATE ANALOG INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE
Authors: PATEL DV GORDON EM SCHMIDT RJ WELLER HN YOUNG MG ZAHLER R BARBACID M CARBONI JM GULLOBROWN JL HUNIHAN L RICCA C ROBINSON S SEIZINGER BR TUOMARI AV MANNE V
Citation: Dv. Patel et al., PHOSPHINYL ACID-BASED BISUBSTRATE ANALOG INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE, Journal of medicinal chemistry, 38(3), 1995, pp. 435-442
REGULATION OF THE SEQUENCE-SPECIFIC DNA-BINDING FUNCTION OF P53 BY PROTEIN-KINASE-C AND PROTEIN PHOSPHATASES
Authors: TAKENAKA I MORIN F SEIZINGER BR KLEY N
Citation: I. Takenaka et al., REGULATION OF THE SEQUENCE-SPECIFIC DNA-BINDING FUNCTION OF P53 BY PROTEIN-KINASE-C AND PROTEIN PHOSPHATASES, The Journal of biological chemistry, 270(10), 1995, pp. 5405-5411
CLONING AND CHARACTERIZATION OF A MOUSE GENE WITH HOMOLOGY TO THE HUMAN VON HIPPEL-LINDAU DISEASE TUMOR-SUPPRESSOR GENE - IMPLICATIONS FOR THE POTENTIAL ORGANIZATION OF THE HUMAN VON HIPPEL-LINDAU DISEASE GENE
Authors: GAO JZ NAGLICH JG LAIDLAW J WHALEY JM SEIZINGER BR KLEY N
Citation: Jz. Gao et al., CLONING AND CHARACTERIZATION OF A MOUSE GENE WITH HOMOLOGY TO THE HUMAN VON HIPPEL-LINDAU DISEASE TUMOR-SUPPRESSOR GENE - IMPLICATIONS FOR THE POTENTIAL ORGANIZATION OF THE HUMAN VON HIPPEL-LINDAU DISEASE GENE, Cancer research, 55(4), 1995, pp. 743-747
FARNESYLTRANSFERASE INHIBITORS BLOCK THE NEUROFIBROMATOSIS TYPE-I (NF1) MALIGNANT PHENOTYPE
Authors: YAN N RICCA C FLETCHER J GLOVER T SEIZINGER BR MANNE V
Citation: N. Yan et al., FARNESYLTRANSFERASE INHIBITORS BLOCK THE NEUROFIBROMATOSIS TYPE-I (NF1) MALIGNANT PHENOTYPE, Cancer research, 55(16), 1995, pp. 3569-3575
P-GLYCOPROTEIN, HER-2 NEU, AND MUTANT P53 EXPRESSION IN HUMAN GYNECOLOGIC TUMORS/
Authors: SCHNEIDER J RUBIO MP BARBAZAN MJ RODRIGUEZESCUDERO FJ SEIZINGER BR CASTRESANA JS
Citation: J. Schneider et al., P-GLYCOPROTEIN, HER-2 NEU, AND MUTANT P53 EXPRESSION IN HUMAN GYNECOLOGIC TUMORS/, Journal of the National Cancer Institute, 86(11), 1994, pp. 850-855
MUTATIONS IN TRANSCRIPT ISOFORMS OF THE NEUROFIBROMATOSIS-2 GENE IN MULTIPLE HUMAN TUMOR TYPES
Authors: BIANCHI AB HARA T RAMESH V GAO JZ KLEINSZANTO AJP MORIN F MENON AG TROFATTER JA GUSELLA JF SEIZINGER BR KLEY N
Citation: Ab. Bianchi et al., MUTATIONS IN TRANSCRIPT ISOFORMS OF THE NEUROFIBROMATOSIS-2 GENE IN MULTIPLE HUMAN TUMOR TYPES, Nature genetics, 6(2), 1994, pp. 185-192
DINUCLEOTIDE REPEAT POLYMORPHISM AT THE D3S666 LOCUS
Authors: KLAUCK SM YAMAKAWA K SEIZINGER BR
Citation: Sm. Klauck et al., DINUCLEOTIDE REPEAT POLYMORPHISM AT THE D3S666 LOCUS, Human molecular genetics, 3(5), 1994, pp. 840-840
DINUCLEOTIDE REPEAT POLYMORPHISM AT THE D3S1255 LOCUS
Authors: KLAUCK SM WHISENANT E WOOD M DRABKIN HA SEIZINGER BR
Citation: Sm. Klauck et al., DINUCLEOTIDE REPEAT POLYMORPHISM AT THE D3S1255 LOCUS, Human molecular genetics, 3(5), 1994, pp. 840-840
GENETIC-BASIS OF NEUROLOGICAL TUMORS
Authors: LOUIS DN SEIZINGER BR
Citation: Dn. Louis et Br. Seizinger, GENETIC-BASIS OF NEUROLOGICAL TUMORS, Bailliere's clinical neurology, 3(2), 1994, pp. 335-352
PEPTIDE-BASED P21(RAS) FARNESYL TRANSFERASE INHIBITORS - SYSTEMATIC MODIFICATION OF THE TETRAPEPTIDE CA(1)A(2)X MOTIF
Authors: LEFTHERIS K KLINE T NATARAJAN S DEVIRGILIO MK CHO YH PLUSCEC J RICCA C ROBINSON S SEIZINGER BR MANNE V MEYERS CA
Citation: K. Leftheris et al., PEPTIDE-BASED P21(RAS) FARNESYL TRANSFERASE INHIBITORS - SYSTEMATIC MODIFICATION OF THE TETRAPEPTIDE CA(1)A(2)X MOTIF, Bioorganic & medicinal chemistry letters, 4(7), 1994, pp. 887-892
IDENTIFICATION OF P53 MUTATIONS BY MEANS OF SINGLE-STRAND CONFORMATION POLYMORPHISM ANALYSIS IN GYNECOLOGICAL TUMORS - COMPARISON WITH THE RESULTS OF IMMUNOHISTOCHEMISTRY
Authors: SCHNEIDER J RUBIO MP RODRIGUEZESCUDERO FJ SEIZINGER BR CASTRESANA JS
Citation: J. Schneider et al., IDENTIFICATION OF P53 MUTATIONS BY MEANS OF SINGLE-STRAND CONFORMATION POLYMORPHISM ANALYSIS IN GYNECOLOGICAL TUMORS - COMPARISON WITH THE RESULTS OF IMMUNOHISTOCHEMISTRY, European journal of cancer, 30A(4), 1994, pp. 504-508
THE NF2 TUMOR-SUPPRESSOR GENE - MUTATIONS IN MULTIPLE TUMOR TYPES ANDINITIAL CHARACTERIZATION OF ITS ENCODED PRODUCT
Authors: KLEY N BIANCHI A HARA T KLEINSZANTO A RAMESH V GUSELLA JF DEPREZ RL ZWARTHOFF E SEIZINGER BR
Citation: N. Kley et al., THE NF2 TUMOR-SUPPRESSOR GENE - MUTATIONS IN MULTIPLE TUMOR TYPES ANDINITIAL CHARACTERIZATION OF ITS ENCODED PRODUCT, Journal of cellular biochemistry, 1994, pp. 189-189
CLONING OF A PUTATIVE MENINGIOMA TUMOR-SUPPRESSOR GENE
Authors: RIEGMAN PHJ DEPREZ KHL GROEN N KORTENHORST U HAGEMEIJER A VANDRUNEN E BOOTSMA D MENON A KLEY N SEIZINGER BR DEJONG P ZWARTHOFF EC
Citation: Phj. Riegman et al., CLONING OF A PUTATIVE MENINGIOMA TUMOR-SUPPRESSOR GENE, Journal of cellular biochemistry, 1994, pp. 193-193
NF2 GENE-MUTATIONS IN MENINGIOMAS AND VESTIBULAR SCHWANNOMAS
Authors: ZWARTHOFF EC BIANCHI AB GROEN NA KLEY N SEIZINGER BR HAGEMEIJER A VANDRUNEN E BOOTSMA D KOPER JW AVEZAAT CJJ DEPREZ RHL
Citation: Ec. Zwarthoff et al., NF2 GENE-MUTATIONS IN MENINGIOMAS AND VESTIBULAR SCHWANNOMAS, Journal of cellular biochemistry, 1994, pp. 194-194
Risultati: 1-25 | 26-36