Authors:
BROTEN T
SCOTT A
SIEGL PKS
FORRAY C
LAGU B
NAGARATHNAM D
WONG WC
MARZABADI M
DHAR TGM
GLUCHOWSKI C
Citation: T. Broten et al., ALPHA-1-ADRENOCEPTOR BLOCKADE INHIBITS DETRUSOR INSTABILITY IN RATS WITH BLADDER OUTLET OBSTRUCTION, The FASEB journal, 12(4), 1998, pp. 2584-2584
Authors:
SELNICK HG
LIVERTON NJ
BALDWIN JJ
BUTCHER JW
CLAREMON DA
ELLIOTT JM
FREIDINGER RM
KING SA
LIBBY BE
MCINTYRE CJ
PRIBUSH DA
REMY DC
SMITH GR
TEBBEN AJ
JURKIEWICZ NK
LYNCH JJ
SALATA JJ
SANGUINETTI MC
SIEGL PKS
SLAUGHTER DE
VYAS K
Citation: Hg. Selnick et al., CLASS-III ANTIARRHYTHMIC ACTIVITY IN-VIVO BY SELECTIVE BLOCKADE OF THE SLOWLY ACTIVATING CARDIAC DELAYED RECTIFIER POTASSIUM CURRENT I-KS BY ,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL]ACETAMIDE, Journal of medicinal chemistry, 40(24), 1997, pp. 3865-3868
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SALATA JJ
JURKIEWICZ NK
WANG J
SIEGL PKS
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Citation: Jj. Salata et al., A NOVEL POTENT AGONIST OF I-KS THAT ACTS VIA A NEGATIVE SHIFT IN THE VOLTAGE-DEPENDENCE OF ACTIVATION, Biophysical journal, 72(2), 1997, pp. 19-19
Citation: Ra. Gabel et al., IN-VIVO PHARMACOLOGY OF L-159,913, A NEW HIGHLY POTENT AND SELECTIVE NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONIST, Clinical and experimental hypertension, 17(6), 1995, pp. 931-953
Authors:
GABEL RA
KIVLIGHN SD
KRAUSE SM
RANAEI R
WILLIAMS DL
WALSH TF
GREENLEE WJ
SIEGL PKS
Citation: Ra. Gabel et al., L-754,142, AN ENDOTHELIN (ET) RECEPTOR ANTAGONIST, REDUCES RADIOCONTRAST INDUCED DECREASES IN RENAL-FUNCTION, Journal of the American Society of Nephrology, 6(3), 1995, pp. 978-978
Authors:
KIVLIGHN SD
GABEL RA
KRAUSE SM
RANAEI R
WILLIAMS DL
WALSH TF
GREENLEE WJ
SIEGL PKS
Citation: Sd. Kivlighn et al., TREATMENT WITH AN ENDOTHELIN (ET) ANTAGONIST PROVIDES A MORE RAPID RETURN TO NORMAL RENAL-FUNCTION FOLLOWING ISCHEMIA-INDUCED ACUTE-RENAL-FAILURE (ARF) IN THE RAT, Journal of the American Society of Nephrology, 6(3), 1995, pp. 982-982
Authors:
KIVLIGHN SD
GABEL R
WILLIAMS DL
WALSH TF
GREENLEE WJ
SIEGL PKS
Citation: Sd. Kivlighn et al., A POSSIBLE ROLE FOR THE ENDOTHELIN-B (ET(B)) RECEPTOR IN ACUTE CYCLOSPORINE-A (CSA) INDUCED NEPHROTOXICITY, Journal of the American Society of Nephrology, 6(3), 1995, pp. 999-999
Authors:
KIVLIGHN SD
ZINGARO GJ
GABEL RA
BROTEN TP
SCHORN TW
SCHAFFER LW
NAYLOR EM
CHAKRAVARTY PK
PATCHETT AA
GREENLEE WJ
SIEGL PKS
Citation: Sd. Kivlighn et al., IN-VIVO PHARMACOLOGY OF A NOVEL AT(1) SELECTIVE ANGIOTENSIN-II RECEPTOR ANTAGONIST, MK-996, American journal of hypertension, 8(1), 1995, pp. 58-66
Authors:
BROTEN TP
SCOTT AL
CARTWRIGHT M
SIEGL PKS
Citation: Tp. Broten et al., PREVENTION OF HYPERTENSION AND CARDIAC PATHOLOGY BY LOSARTAN DURING CHRONIC NITRIC-OXIDE INHIBITION, The FASEB journal, 9(3), 1995, pp. 329-329
Authors:
KIVLIGHN SD
HUCKLE WR
ZINGARO GJ
RIVERO RA
LOTTI VJ
CHANG RSL
SCHORN TW
KEVIN N
JOHNSON RG
GREENLEE WJ
SIEGL PKS
Citation: Sd. Kivlighn et al., DISCOVERY OF L-162,313 - A NONPEPTIDE THAT MIMICS THE BIOLOGICAL ACTIONS OF ANGIOTENSIN-II, American journal of physiology. Regulatory, integrative and comparative physiology, 37(3), 1995, pp. 820-823
Citation: Pks. Siegl et al., PHARMACOLOGY OF LOSARTAN, AN ANGIOTENSIN-II RECEPTOR ANTAGONIST, IN ANIMAL-MODELS OF HYPERTENSION, Journal of hypertension, 13, 1995, pp. 15-21
Authors:
ASHTON WT
CHANG LL
FLANAGAN KL
MANTLO NB
ONDEYKA DL
KIM D
DELASZLO SE
GLINKA TW
RIVERO RA
KEVIN NJ
CHANG RSL
SIEGL PKS
KIVLIGHN SD
GREENLEE WJ
Citation: Wt. Ashton et al., AT(1) AT(2)-BALANCED ANGIOTENSIN-II ANTAGONISTS/, European journal of medicinal chemistry, 30, 1995, pp. 255-266
Authors:
WILLIAMS DL
MURPHY KL
NOLAN NA
OBRIEN JA
PETTIBONE DJ
KIVLIGHN SD
KRAUSE SM
LIS EV
ZINGARO GJ
GABEL RA
CLAYTON FC
SIEGL PKS
ZHANG K
NAUE J
VYAS K
WALSH TF
FITCH KJ
CHAKRAVARTY PK
GREENLEE WJ
CLINESCHMIDT BV
Citation: Dl. Williams et al., PHARMACOLOGY OF L-754,142, A HIGHLY POTENT, ORALLY-ACTIVE, NONPEPTIDYL ENDOTHELIN ANTAGONIST, The Journal of pharmacology and experimental therapeutics, 275(3), 1995, pp. 1518-1526
Authors:
BEAUCHAMP HT
CHANG RSL
SIEGL PKS
GIBSON RE
Citation: Ht. Beauchamp et al., IN-VIVO RECEPTOR OCCUPANCY OF THE ANGIOTENSIN-II RECEPTOR BY NONPEPTIDE ANTAGONISTS - RELATIONSHIP TO IN-VITRO AFFINITIES AND IN-VIVO PHARMACOLOGICAL POTENCY, The Journal of pharmacology and experimental therapeutics, 272(2), 1995, pp. 612-618
Citation: Ll. Chang et al., POTENT AND ORALLY-ACTIVE ANGIOTENSIN-II RECEPTOR ANTAGONISTS WITH EQUAL AFFINITY FOR HUMAN AT(1) AND AT(2) SUBTYPES, Journal of medicinal chemistry, 38(19), 1995, pp. 3741-3758
Authors:
CHANG RSL
LOTTI VJ
CHEN TB
OMALLEY SS
BENDESKY RJ
KLING PJ
KIVLIGHN SD
SIEGL PKS
ONDEYKA D
GREENLEE WJ
MANTLO NB
Citation: Rsl. Chang et al., IN-VITRO PHARMACOLOGY OF AN ANGIOTENSIN AT(1) RECEPTOR ANTAGONIST WITH BALANCED AFFINITY FOR AT(2) RECEPTORS, European journal of pharmacology, 294(2-3), 1995, pp. 429-437
Authors:
KIVLIGHN SD
ZINGARO GJ
GABEL RA
BROTEN TP
CHANG RSL
ONDEYKA DL
MANTLO NB
GIBSON RE
GREENLEE WJ
SIEGL PKS
Citation: Sd. Kivlighn et al., IN-VIVO PHARMACOLOGY OF AN ANGIOTENSIN AT(1) RECEPTOR ANTAGONIST WITHBALANCED AFFINITY FOR ANGIOTENSIN AT(2) RECEPTORS, European journal of pharmacology, 294(2-3), 1995, pp. 439-450
Authors:
CHANG LL
ASHTON WT
FLANAGAN KL
RIVERO RA
CHEN TB
OMALLEY SS
ZINGARO GJ
KIVLIGHN SD
SIEGL PKS
LOTTI VJ
CHANG RSL
GREENLEE WJ
Citation: Ll. Chang et al., POTENT TRIAZOLINONE-BASED ANGIOTENSIN-II RECEPTOR ANTAGONISTS WITH EQUIVALENT AFFINITY FOR BOTH THE AT(1) AND AT(2) SUBTYPES, Bioorganic & medicinal chemistry letters, 4(23), 1994, pp. 2787-2792
Citation: Tw. Glinka et al., DEVELOPMENT OF ANGIOTENSIN-II ANTAGONISTS WITH EQUIPOTENT AFFINITY FOR HUMAN AT(1) AND AT(2) RECEPTOR SUBTYPES, Bioorganic & medicinal chemistry letters, 4(19), 1994, pp. 2337-2342
Authors:
NAYLOR EM
CHAKRAVARTY PK
COSTELLO CA
CHANG RS
CHEN TB
FAUST KA
LOTTI VJ
KIVLIGHN SD
ZINGARO GJ
SIEGL PKS
WONG PC
CARINI DJ
WEXLER RR
PATCHETT AA
GREENLEE WJ
Citation: Em. Naylor et al., POTENT IMIDAZOLE ANGIOTENSIN-II ANTAGONISTS - ACYL SULFONAMIDES AND ACYL SULFAMIDES AS TETRAZOLE REPLACEMENTS, Bioorganic & medicinal chemistry letters, 4(1), 1994, pp. 69-74
Citation: Pk. Chakravarty et al., QUINAZOLINONE BIPHENYL ACYLSULFONAMIDES - A POTENT NEW CLASS OF ANGIOTENSIN-II RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 4(1), 1994, pp. 75-80
Citation: Tw. Glinka et al., A NEW CLASS OF BALANCED AT(1) AT(2) ANGIOTENSIN-II ANTAGONISTS - QUINAZOLINONE AII ANTAGONISTS WITH ACYLSULFONAMIDE AND SULFONYLCARBAMATE ACIDIC FUNCTIONALITIES/, Bioorganic & medicinal chemistry letters, 4(1), 1994, pp. 81-86