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Results: 1-23 |
Results: 23
NEUTRALASE(TM) REVERSES THE ANTI-COAGULANT BUT NOT THE ANTITHROMBOTICACTIVITY OF HEPARIN IN A RABBIT MODEL OF VENOUS THROMBOSIS
Authors: SILVER PJ BROUGHTON R BOUTHILLIER J
Citation: Pj. Silver et al., NEUTRALASE(TM) REVERSES THE ANTI-COAGULANT BUT NOT THE ANTITHROMBOTICACTIVITY OF HEPARIN IN A RABBIT MODEL OF VENOUS THROMBOSIS, Thrombosis research, 91(3), 1998, pp. 143-150
HEPARINASE-III LIMITS RAT ARTERIAL SMOOTH-MUSCLE CELL-PROLIFERATION IN-VITRO AND IN-VIVO
Authors: SILVER PJ MOREAU JP DENHOLM E LIN YQ NGUYEN L BENNETT C RECKTENWALD A DEBLOIS D BAKER S RANGER S
Citation: Pj. Silver et al., HEPARINASE-III LIMITS RAT ARTERIAL SMOOTH-MUSCLE CELL-PROLIFERATION IN-VITRO AND IN-VIVO, European journal of pharmacology, 351(1), 1998, pp. 79-83
CARDIOVASCULAR ACTIVITY OF WIN-65579, A NOVEL INHIBITOR OF CYCLIC-GMPPHOSPHODIESTERASE-5
Authors: SILVER PJ PAGANI ED DUNDORE RL DEGARAVILLA L BODE DC BACON ER
Citation: Pj. Silver et al., CARDIOVASCULAR ACTIVITY OF WIN-65579, A NOVEL INHIBITOR OF CYCLIC-GMPPHOSPHODIESTERASE-5, European journal of pharmacology, 349(2-3), 1998, pp. 263-268
IMIDAZOTRIAZINONE INHIBITORS OF THE CA2-CALMODULIN SENSITIVE PHOSPHODIESTERASE (PDE-I)()
Authors: HLASTA DJ BODE DC COURT JJ DESAI RC PAGANI ED SILVER PJ
Citation: Dj. Hlasta et al., IMIDAZOTRIAZINONE INHIBITORS OF THE CA2-CALMODULIN SENSITIVE PHOSPHODIESTERASE (PDE-I)(), Bioorganic & medicinal chemistry letters, 7(1), 1997, pp. 89-94
ZAPRINAST, BUT NOT DIPYRIDAMOLE, REVERSES HEMODYNAMIC TOLERANCE TO NITROGLYCERIN IN-VIVO
Authors: DEGARAVILLA L PAGANI ED BUCHHOLZ RA DUNDORE R BODE DC VOLBERG ML JACKSON KN PRATT P SILVER PJ
Citation: L. Degaravilla et al., ZAPRINAST, BUT NOT DIPYRIDAMOLE, REVERSES HEMODYNAMIC TOLERANCE TO NITROGLYCERIN IN-VIVO, European journal of pharmacology, 313(1-2), 1996, pp. 89-96
IN-VITRO CHARACTERIZATION OF A NOVEL SERIES OF PLATELET-DERIVED GROWTH-FACTOR RECEPTOR TYROSINE KINASE INHIBITORS
Authors: SAWUTZ DG BODE DC BRIGGS GM REID JR CANNIFF P CALDWELL L FALTYNEK CR MILLER D DUNN JA DEGARAVILLA L GUILES JW WEIGELT C MICHNE W TREASURYWALA AM SILVER PJ
Citation: Dg. Sawutz et al., IN-VITRO CHARACTERIZATION OF A NOVEL SERIES OF PLATELET-DERIVED GROWTH-FACTOR RECEPTOR TYROSINE KINASE INHIBITORS, Biochemical pharmacology, 51(12), 1996, pp. 1631-1638
EVIDENCE FOR MULTIPLE ANTIARRHYTHMIC BINDING-SITES ON THE CARDIAC RAPIDLY ACTIVATING DELAYED RECTIFIER K+ CHANNEL
Authors: CHADWICK CC KRAFTE DS OCONNOR B VOLBERG WA EZRIN AM JOHNSON RE SILVER PJ
Citation: Cc. Chadwick et al., EVIDENCE FOR MULTIPLE ANTIARRHYTHMIC BINDING-SITES ON THE CARDIAC RAPIDLY ACTIVATING DELAYED RECTIFIER K+ CHANNEL, Drug development research, 34(4), 1995, pp. 376-380
BIOLOGICAL-ACTIVITY OF WIN-63759, AN ORALLY BIOAVAILABLE INHIBITOR OFHUMAN NEUTROPHIL ELASTASE
Authors: SILVER PJ GORDON RJ PAGANI ED JOHNSON JA MAYCOCK AL DUNLAP RP FERGUSON EW FRANKE CA DROZD ML ROBINSON DT EICKHOFF WM BAIZMAN ER SUBRAMANYAM C DESAI RC HLASTA DJ NEWTON JF
Citation: Pj. Silver et al., BIOLOGICAL-ACTIVITY OF WIN-63759, AN ORALLY BIOAVAILABLE INHIBITOR OFHUMAN NEUTROPHIL ELASTASE, Drug development research, 34(3), 1995, pp. 306-316
SPECIES-DEPENDENT PHARMACODYNAMIC EFFECTS OF THE SELECTIVE LOW K-M CYCLIC-AMP PHOSPHODIESTERASE-III INHIBITORS WIN-58993 AND WIN-62005
Authors: DUNDORE RL PAGANI ED BODE DC BACON ER SINGH B LESHER GY BUCHHOLZ RA SILVER PJ
Citation: Rl. Dundore et al., SPECIES-DEPENDENT PHARMACODYNAMIC EFFECTS OF THE SELECTIVE LOW K-M CYCLIC-AMP PHOSPHODIESTERASE-III INHIBITORS WIN-58993 AND WIN-62005, Journal of cardiovascular pharmacology, 25(1), 1995, pp. 14-21
ORALLY BIOAVAILABLE BENZISOTHIAZOLONE INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE
Authors: HLASTA DJ SUBRAMANYAM C BELL MR CARABATEAS PM COURT JJ DESAI RC DROZD ML EICKHOFF WM FERGUSON EW GORDON RJ JOHNSON JA KUMAR V MAYCOCK AL MUELLER KR PAGANI ED ROBINSON DT SAINDANE MT SILVER PJ SUBRAMANIAN S DUNLAP RP FRANKE CA MURA AJ ROWLANDS AG
Citation: Dj. Hlasta et al., ORALLY BIOAVAILABLE BENZISOTHIAZOLONE INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE, Journal of medicinal chemistry, 38(5), 1995, pp. 739-744
NOVEL AND POTENT ADENOSINE 3',5'-CYCLIC PHOSPHATE PHOSPHODIESTERASE-III INHIBITORS - THIAZOLO[4,5-B][1,6]NAPHTHYRIDIN-2-ONES
Authors: SINGH B BACON ER LESHER GY ROBINSON S PENNOCK PO BODE DC PAGANI ED BENTLEY RG CONNELL MJ HAMEL LT SILVER PJ
Citation: B. Singh et al., NOVEL AND POTENT ADENOSINE 3',5'-CYCLIC PHOSPHATE PHOSPHODIESTERASE-III INHIBITORS - THIAZOLO[4,5-B][1,6]NAPHTHYRIDIN-2-ONES, Journal of medicinal chemistry, 38(14), 1995, pp. 2546-2550
SULFONAMIDOPHENYL)-1-PHENYL-1H-2,4-BENZODIAZEPINES - A NOVEL CLASS-III ANTIARRHYTHMIC AGENTS
Authors: JOHNSON RE SILVER PJ BECKER R BIRSNER NC BOHNET EA BRIGGS GM BUSACCA CA CANNIFF P CARABATEAS PM CHADWICK CC DAMBRA T DUNDORE RL DUNG JS EZRIN AM GORCZYCA W HABEEB PG KRAFTE PHDS PILLING GM OCONNOR B SAINDANE MT SCHLEGEL DC STANKUS GP SWESTOCK J VOLBERG WA
Citation: Re. Johnson et al., SULFONAMIDOPHENYL)-1-PHENYL-1H-2,4-BENZODIAZEPINES - A NOVEL CLASS-III ANTIARRHYTHMIC AGENTS, Journal of medicinal chemistry, 38(14), 1995, pp. 2551-2556
PHARMACOLOGICAL MODULATION OF HUMAN CARDIAC NA+ CHANNELS
Authors: KRAFTE DS DAVISON K DUGRENIER N ESTEP K JOSEF K BARCHI RL KALLEN RG SILVER PJ EZRIN AM
Citation: Ds. Krafte et al., PHARMACOLOGICAL MODULATION OF HUMAN CARDIAC NA+ CHANNELS, European journal of pharmacology. Molecular pharmacology section, 266(3), 1994, pp. 245-254
OPTIMIZING ORGANIZATION AND EFFECTIVENESS OF PHARMACEUTICAL DISCOVERYBY MOLECULAR TARGET RATHER THAN BY THERAPEUTIC AREA
Authors: SILVER PJ
Citation: Pj. Silver, OPTIMIZING ORGANIZATION AND EFFECTIVENESS OF PHARMACEUTICAL DISCOVERYBY MOLECULAR TARGET RATHER THAN BY THERAPEUTIC AREA, Drug development research, 32(1), 1994, pp. 1-5
PHARMACOLOGICAL AND PHARMACODYNAMIC EFFECTS OF THE SELECTIVE LOW K-M CYCLIC-AMP PHOSPHODIESTERASE-III INHIBITORS WIN-63291 AND WIN-62582
Authors: PAGANI ED DUNDORE RL BODE DC BACON ER SINGH B LESHER GY BUCHHOLZ RA SILVER PJ
Citation: Ed. Pagani et al., PHARMACOLOGICAL AND PHARMACODYNAMIC EFFECTS OF THE SELECTIVE LOW K-M CYCLIC-AMP PHOSPHODIESTERASE-III INHIBITORS WIN-63291 AND WIN-62582, Journal of cardiovascular pharmacology, 24(3), 1994, pp. 403-410
CYCLIC-GMP POTENTIATION BY WIN-58237, A NOVEL CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE INHIBITOR
Authors: SILVER PJ DUNDORE RL BODE DC DEGARAVILLA L BUCHHOLZ RA VANALLER G HAMEL LT BACON E SINGH B LESHER GY HLASTA D PAGANI ED
Citation: Pj. Silver et al., CYCLIC-GMP POTENTIATION BY WIN-58237, A NOVEL CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE INHIBITOR, The Journal of pharmacology and experimental therapeutics, 271(3), 1994, pp. 1143-1149
NOVEL CAMP PDE-III INHIBITORS - IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THIAZOLO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR ANALOGS
Authors: SINGH B BACON ER ROBINSON S FRITZ RK LESHER GY KUMAR V DORITY JA REUMAN M KUO GH EISSENSTAT MA PAGANI ED BODE DC BENTLEY RG CONNELL MJ HAMEL LT SILVER PJ
Citation: B. Singh et al., NOVEL CAMP PDE-III INHIBITORS - IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THIAZOLO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR ANALOGS, Journal of medicinal chemistry, 37(2), 1994, pp. 248-254
5,7-DIMETHOXY-3-(4-PYRIDINYL)QUINOLINE IS A POTENT AND SELECTIVE INHIBITOR OF HUMAN VASCULAR BETA-TYPE PLATELET-DERIVED GROWTH-FACTOR RECEPTOR TYROSINE KINASE
Authors: DOLLE RE DUNN JA BOBKO M SINGH B KUSTER JE BAIZMAN E HARRIS AL SAWUTZ DG MILLER D WANG S FALTYNEK CR XIE W SARUP J BODE DC PAGANI ED SILVER PJ
Citation: Re. Dolle et al., 5,7-DIMETHOXY-3-(4-PYRIDINYL)QUINOLINE IS A POTENT AND SELECTIVE INHIBITOR OF HUMAN VASCULAR BETA-TYPE PLATELET-DERIVED GROWTH-FACTOR RECEPTOR TYROSINE KINASE, Journal of medicinal chemistry, 37(17), 1994, pp. 2627-2629
OCULAR EFFECTS OF TOPICAL ADMINISTRATION OF THE PHOSPHODIESTERASE-IIIINHIBITOR MILRINONE IN RABBITS AND CATS
Authors: LEE KC SILVER PJ BODE DC GHEREZGHIHER T
Citation: Kc. Lee et al., OCULAR EFFECTS OF TOPICAL ADMINISTRATION OF THE PHOSPHODIESTERASE-IIIINHIBITOR MILRINONE IN RABBITS AND CATS, Methods and findings in experimental and clinical pharmacology, 15(8), 1993, pp. 527-534
EFFECT OF CALCIUM-BINDING PROTEIN MODULATORS ON MYOFIBRILLAR MGATPASEACTIVITY AND CGMP-INHIBITABLE PHOSPHODIESTERASE ACTIVITY FROM HUMAN CARDIAC-MUSCLE
Authors: PAGANI ED OCONNOR B ALLEN PD HILLE D SILVER PJ
Citation: Ed. Pagani et al., EFFECT OF CALCIUM-BINDING PROTEIN MODULATORS ON MYOFIBRILLAR MGATPASEACTIVITY AND CGMP-INHIBITABLE PHOSPHODIESTERASE ACTIVITY FROM HUMAN CARDIAC-MUSCLE, Drug development research, 29(3), 1993, pp. 195-202
4,5-DIHYDRO-1-PHENYL-1H-2,4-BENZODIAZEPINES - NOVEL ANTIARRHYTHMIC AGENTS
Authors: JOHNSON RE BAIZMAN ER BECKER C BOHNET EA BELL RH BIRSNER NC BUSACCA CA CARABATEAS PM CHADWICK CC GRUETT MD HANE JT HERRMANN JL JOSEF KA KRAFTE DS KULLNIG RK MICHNE WF PAREENE PA PERNI RB OCONNOR B SALVADOR UJ SANNER MA SCHLEGEL DC SILVER PJ SWESTOCK J STANKUS GP TATLOCK JH VOLBERG WA WEIGELT CC ERZIN AM
Citation: Re. Johnson et al., 4,5-DIHYDRO-1-PHENYL-1H-2,4-BENZODIAZEPINES - NOVEL ANTIARRHYTHMIC AGENTS, Journal of medicinal chemistry, 36(22), 1993, pp. 3361-3370
ZAPRINAST INCREASES CYCLIC-GMP LEVELS IN PLASMA AND IN AORTIC TISSUE OF RATS
Authors: DUNDORE RL CLAS DM WHEELER LT HABEEB PG BODE DC BUCHHOLZ RA SILVER PJ PAGANI ED
Citation: Rl. Dundore et al., ZAPRINAST INCREASES CYCLIC-GMP LEVELS IN PLASMA AND IN AORTIC TISSUE OF RATS, European journal of pharmacology, 249(3), 1993, pp. 293-297
REVERSAL OF NITROGLYCERIN TOLERANCE IN-VITRO BY THE CGMP-PHOSPHODIESTERASE INHIBITOR ZAPRINAST
Authors: PAGANI ED VANALLER GS OCONNOR B SILVER PJ
Citation: Ed. Pagani et al., REVERSAL OF NITROGLYCERIN TOLERANCE IN-VITRO BY THE CGMP-PHOSPHODIESTERASE INHIBITOR ZAPRINAST, European journal of pharmacology, 243(2), 1993, pp. 141-147
Risultati: 1-23 |