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Results: 1-25 | 26-34
Results: 1-25/34
CLONING OF MOUSE GAMMA-GLUTAMYL HYDROLASE IN THE FORM OF 2 CDNA VARIANTS WITH DIFFERENT 5' ENDS AND ENCODING ALTERNATE LEADER PEPTIDE SEQUENCES
Authors: ESAKI T ROY K YAO R GALIVAN J SIROTNAK FM
Citation: T. Esaki et al., CLONING OF MOUSE GAMMA-GLUTAMYL HYDROLASE IN THE FORM OF 2 CDNA VARIANTS WITH DIFFERENT 5' ENDS AND ENCODING ALTERNATE LEADER PEPTIDE SEQUENCES, Gene, 219(1-2), 1998, pp. 37-44
STRUCTURAL-ANALYSIS OF THE HUMAN RFC-1 GENE ENCODING A FOLATE TRANSPORTER REVEALS MULTIPLE PROMOTERS AND ALTERNATIVELY SPLICED TRANSCRIPTS WITH 5'-END HETEROGENEITY
Authors: TOLNER B ROY K SIROTNAK FM
Citation: B. Tolner et al., STRUCTURAL-ANALYSIS OF THE HUMAN RFC-1 GENE ENCODING A FOLATE TRANSPORTER REVEALS MULTIPLE PROMOTERS AND ALTERNATIVELY SPLICED TRANSCRIPTS WITH 5'-END HETEROGENEITY, Gene, 211(2), 1998, pp. 331-341
A NEW ANALOG OF 10-DEAZAAMINOPTERIN WITH MARKEDLY ENHANCED CURATIVE EFFECTS AGAINST HUMAN TUMOR XENOGRAFTS IN MICE
Authors: SIROTNAK FM DEGRAW JI COLWELL WT PIPER JR
Citation: Fm. Sirotnak et al., A NEW ANALOG OF 10-DEAZAAMINOPTERIN WITH MARKEDLY ENHANCED CURATIVE EFFECTS AGAINST HUMAN TUMOR XENOGRAFTS IN MICE, Cancer chemotherapy and pharmacology, 42(4), 1998, pp. 313-318
CHROMOSOMAL LOCALIZATION OF THE MURINE RFC-1 GENE ENCODING A FOLATE TRANSPORTER AND ITS AMPLIFICATION IN AN ANTIFOLATE RESISTANT VARIANT OVERPRODUCING THE TRANSPORTER
Authors: ROY K CHIAO JH SPENGLER BA TOLNER B YANG CH BIEDLER JL SIROTNAK FM
Citation: K. Roy et al., CHROMOSOMAL LOCALIZATION OF THE MURINE RFC-1 GENE ENCODING A FOLATE TRANSPORTER AND ITS AMPLIFICATION IN AN ANTIFOLATE RESISTANT VARIANT OVERPRODUCING THE TRANSPORTER, Cancer genetics and cytogenetics, 105(1), 1998, pp. 29-38
A SINGLE AMINO-ACID DIFFERENCE WITHIN THE FOLATE TRANSPORTER ENCODED BY THE MURINE RFC-1 GENE SELECTIVELY ALTERS ITS INTERACTION WITH FOLATE ANALOGS - IMPLICATIONS FOR INTRINSIC ANTIFOLATE RESISTANCE AND DIRECTIONAL ORIENTATION OF THE TRANSPORTER WITHIN THE PLASMA-MEMBRANE OF TUMOR-CELLS
Authors: ROY K TOLNER B CHIAO JH SIROTNAK FM
Citation: K. Roy et al., A SINGLE AMINO-ACID DIFFERENCE WITHIN THE FOLATE TRANSPORTER ENCODED BY THE MURINE RFC-1 GENE SELECTIVELY ALTERS ITS INTERACTION WITH FOLATE ANALOGS - IMPLICATIONS FOR INTRINSIC ANTIFOLATE RESISTANCE AND DIRECTIONAL ORIENTATION OF THE TRANSPORTER WITHIN THE PLASMA-MEMBRANE OF TUMOR-CELLS, The Journal of biological chemistry, 273(5), 1998, pp. 2526-2531
ORGANIZATION, STRUCTURE AND ALTERNATE SPLICING OF THE MURINE RFC-1 GENE ENCODING A FOLATE TRANSPORTER
Authors: TOLNER B ROY K SIROTNAK FM
Citation: B. Tolner et al., ORGANIZATION, STRUCTURE AND ALTERNATE SPLICING OF THE MURINE RFC-1 GENE ENCODING A FOLATE TRANSPORTER, Gene, 189(1), 1997, pp. 1-7
THE SECALOSIDES, NOVEL TUMOR-CELL GROWTH-INHIBITORY GLYCOSIDES FROM APOLLEN EXTRACT
Authors: JATON JC ROULIN K ROSE K SIROTNAK FM LEWENSTEIN A BRUNNER G FANKHAUSER CP BURGER U
Citation: Jc. Jaton et al., THE SECALOSIDES, NOVEL TUMOR-CELL GROWTH-INHIBITORY GLYCOSIDES FROM APOLLEN EXTRACT, Journal of natural products, 60(4), 1997, pp. 356-360
ANALOGS OF METHOTREXATE IN RHEUMATOID-ARTHRITIS .1. EFFECTS OF 10-DEAZAAMINOPTERIN ANALOGS ON TYPE-II COLLAGEN-INDUCED ARTHRITIS IN MICE
Authors: DEGRAW JI COLWELL WT CRASE J SMITH RL PIPER JR WAUD WR SIROTNAK FM
Citation: Ji. Degraw et al., ANALOGS OF METHOTREXATE IN RHEUMATOID-ARTHRITIS .1. EFFECTS OF 10-DEAZAAMINOPTERIN ANALOGS ON TYPE-II COLLAGEN-INDUCED ARTHRITIS IN MICE, Journal of medicinal chemistry, 40(3), 1997, pp. 370-376
ANALOGS OF METHOTREXATE IN RHEUMATOID-ARTHRITIS .2. EFFECTS OF 5-DEAZAAMINOPTERIN, 5,10-DIDEAZAAMINOPTERIN, AND ANALOGS ON TYPE-II COLLAGEN-INDUCED ARTHRITIS IN MICE
Authors: PIPER JR DEGRAW JI COLWELL WT JOHNSON CA SMITH RL WAUD WR SIROTNAK FM
Citation: Jr. Piper et al., ANALOGS OF METHOTREXATE IN RHEUMATOID-ARTHRITIS .2. EFFECTS OF 5-DEAZAAMINOPTERIN, 5,10-DIDEAZAAMINOPTERIN, AND ANALOGS ON TYPE-II COLLAGEN-INDUCED ARTHRITIS IN MICE, Journal of medicinal chemistry, 40(3), 1997, pp. 377-384
ADDITIONAL ORGANIZATIONAL FEATURES OF THE MURINE FOLYLPOLYGLUTAMATE SYNTHETASE GENE - 2 REMOTELY SITUATED EXONS ENCODING AN ALTERNATE 5'-END AND PROXIMAL OPEN READING FRAME UNDER THE CONTROL OF A 2ND PROMOTER
Authors: ROY K MITSUGI K SIROTNAK FM
Citation: K. Roy et al., ADDITIONAL ORGANIZATIONAL FEATURES OF THE MURINE FOLYLPOLYGLUTAMATE SYNTHETASE GENE - 2 REMOTELY SITUATED EXONS ENCODING AN ALTERNATE 5'-END AND PROXIMAL OPEN READING FRAME UNDER THE CONTROL OF A 2ND PROMOTER, The Journal of biological chemistry, 272(9), 1997, pp. 5587-5593
RFC-1 GENE-EXPRESSION REGULATES FOLATE ABSORPTION IN MOUSE SMALL-INTESTINE
Authors: CHIAO JH ROY K TOLNER B YANG CH SIROTNAK FM
Citation: Jh. Chiao et al., RFC-1 GENE-EXPRESSION REGULATES FOLATE ABSORPTION IN MOUSE SMALL-INTESTINE, The Journal of biological chemistry, 272(17), 1997, pp. 11165-11170
POSTTRANSCRIPTIONALLY MEDIATED DECREASES IN FOLYLPOLYGLUTAMATE SYNTHETASE GENE-EXPRESSION IN SOME FOLATE ANALOG-RESISTANT VARIANTS OF THE L1210 CELL - EVIDENCE FOR AN ALTERED COGNATE MESSENGER-RNA IN THE VARIANTS AFFECTING THE RATE OF DE-NOVO SYNTHESIS OF THE ENZYME
Authors: ROY K EGAN MG SIRLIN S SIROTNAK FM
Citation: K. Roy et al., POSTTRANSCRIPTIONALLY MEDIATED DECREASES IN FOLYLPOLYGLUTAMATE SYNTHETASE GENE-EXPRESSION IN SOME FOLATE ANALOG-RESISTANT VARIANTS OF THE L1210 CELL - EVIDENCE FOR AN ALTERED COGNATE MESSENGER-RNA IN THE VARIANTS AFFECTING THE RATE OF DE-NOVO SYNTHESIS OF THE ENZYME, The Journal of biological chemistry, 272(11), 1997, pp. 6903-6908
HIGH-DOSE EDATREXATE WITH ORAL LEUCOVORIN RESCUE - A PHASE-I AND CLINICAL PHARMACOLOGICAL STUDY IN ADULTS WITH ADVANCED CANCER
Authors: PISTERS KMW TYSON LB TONG W FLEISHER M MILLER VA GRANT SC PFISTER DG RIGAS JR DENSMORE CL KROL G HEELAN RT SIROTNAK FM BERTINO JR KRIS MG
Citation: Kmw. Pisters et al., HIGH-DOSE EDATREXATE WITH ORAL LEUCOVORIN RESCUE - A PHASE-I AND CLINICAL PHARMACOLOGICAL STUDY IN ADULTS WITH ADVANCED CANCER, Clinical cancer research, 2(11), 1996, pp. 1819-1824
SCHEDULE-DEPENDENT SYNERGISM OF TAXOL OR TAXOTERE WITH EDATREXATE AGAINST HUMAN BREAST-CANCER CELLS IN-VITRO
Authors: CHOU TC OTTER GM SIROTNAK FM
Citation: Tc. Chou et al., SCHEDULE-DEPENDENT SYNERGISM OF TAXOL OR TAXOTERE WITH EDATREXATE AGAINST HUMAN BREAST-CANCER CELLS IN-VITRO, Cancer chemotherapy and pharmacology, 37(3), 1996, pp. 222-228
ANALOGS OF 10-DEAZAAMINOPTERIN AND 5-ALKYL-5,10-DIDEAZAAMINOPTERIN WITH THE 4-SUBSTITUTED 1-NAPHTHOYL GROUP IN THE PLACE OF 4-SUBSTITUTED BENZOYL
Authors: PIPER JR RAMAMURTHY B JOHNSON CA OTTER GM SIROTNAK FM
Citation: Jr. Piper et al., ANALOGS OF 10-DEAZAAMINOPTERIN AND 5-ALKYL-5,10-DIDEAZAAMINOPTERIN WITH THE 4-SUBSTITUTED 1-NAPHTHOYL GROUP IN THE PLACE OF 4-SUBSTITUTED BENZOYL, Journal of medicinal chemistry, 39(2), 1996, pp. 614-618
ORGANIZATION AND ALTERNATE SPLICING OF THE MURINE FOLYLPOLYGLUTAMATE SYNTHETASE GENE - DIFFERENT SPLICE VARIANTS IN L1210 CELLS ENCODE MITOCHONDRIAL OR CYTOSOLIC FORMS OF THE ENZYME
Authors: ROY K MITSUGI K SIROTNAK FM
Citation: K. Roy et al., ORGANIZATION AND ALTERNATE SPLICING OF THE MURINE FOLYLPOLYGLUTAMATE SYNTHETASE GENE - DIFFERENT SPLICE VARIANTS IN L1210 CELLS ENCODE MITOCHONDRIAL OR CYTOSOLIC FORMS OF THE ENZYME, The Journal of biological chemistry, 271(39), 1996, pp. 23820-23827
9-SUBSTITUTED ACRIDINE-DERIVATIVES WITH LONG HALF-LIFE AND POTENT ANTITUMOR-ACTIVITY - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS
Authors: SU TL CHOU TC KIM JY HUANG JT CISZEWSKA G REN WY OTTER GM SIROTNAK FM WATANABE KA
Citation: Tl. Su et al., 9-SUBSTITUTED ACRIDINE-DERIVATIVES WITH LONG HALF-LIFE AND POTENT ANTITUMOR-ACTIVITY - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS, Journal of medicinal chemistry, 38(17), 1995, pp. 3226-3235
FURTHER EVALUATION OF 5-ALKYL-5-DEAZA ANTIFOLATES - 5-PROPYL-5-DEAZA AND 5-BUTYL-5-DEAZA ANALOGS OF AMINOPTERIN AND METHOTREXATE
Authors: PIPER JR RAMAMURTHY B JOHNSON CA MADDRY JA OTTER GM SIROTNAK FM
Citation: Jr. Piper et al., FURTHER EVALUATION OF 5-ALKYL-5-DEAZA ANTIFOLATES - 5-PROPYL-5-DEAZA AND 5-BUTYL-5-DEAZA ANALOGS OF AMINOPTERIN AND METHOTREXATE, Journal of heterocyclic chemistry, 32(4), 1995, pp. 1205-1212
FUNCTIONAL-STUDIES OF P-GLYCOPROTEIN IN INSIDE-OUT PLASMA-MEMBRANE VESICLES DERIVED FROM MURINE ERYTHROLEUKEMIA-CELLS OVEREXPRESSING MDR-3 (VOL 269, PG 31059, 1994)
Authors: SCHLEMMER SR SIROTNAK FM
Citation: Sr. Schlemmer et Fm. Sirotnak, FUNCTIONAL-STUDIES OF P-GLYCOPROTEIN IN INSIDE-OUT PLASMA-MEMBRANE VESICLES DERIVED FROM MURINE ERYTHROLEUKEMIA-CELLS OVEREXPRESSING MDR-3 (VOL 269, PG 31059, 1994), The Journal of biological chemistry, 270(7), 1995, pp. 3462-3462
LIGAND-DIRECTED IMMUNOAFFINITY PURIFICATION AND PROPERTIES OF THE ONE-CARBON, REDUCED FOLATE TRANSPORTER - INTERSPECIES IMMUNO-CROSS-REACTIVITY AND EXPRESSION OF THE NATIVE TRANSPORTER IN MURINE AND HUMAN TUMOR-CELLS AND THEIR TRANSPORT-ALTERED VARIANTS
Authors: CHIAO JH YANG CH ROY K PAIN J SIROTNAK FM
Citation: Jh. Chiao et al., LIGAND-DIRECTED IMMUNOAFFINITY PURIFICATION AND PROPERTIES OF THE ONE-CARBON, REDUCED FOLATE TRANSPORTER - INTERSPECIES IMMUNO-CROSS-REACTIVITY AND EXPRESSION OF THE NATIVE TRANSPORTER IN MURINE AND HUMAN TUMOR-CELLS AND THEIR TRANSPORT-ALTERED VARIANTS, The Journal of biological chemistry, 270(50), 1995, pp. 29698-29704
DIFFERENT ANTIFOLATE-RESISTANT L1210 CELL VARIANTS WITH EITHER INCREASED OR DECREASED FOLYLPOLYGLUTAMATE SYNTHETASE GENE-EXPRESSION AT THE LEVEL OF MESSENGER-RNA TRANSCRIPTION
Authors: ROY K MITSUGI K SIRLIN S SHANE B SIROTNAK FM
Citation: K. Roy et al., DIFFERENT ANTIFOLATE-RESISTANT L1210 CELL VARIANTS WITH EITHER INCREASED OR DECREASED FOLYLPOLYGLUTAMATE SYNTHETASE GENE-EXPRESSION AT THE LEVEL OF MESSENGER-RNA TRANSCRIPTION, The Journal of biological chemistry, 270(45), 1995, pp. 26918-26922
FUNCTIONAL MODULATION OF MULTIDRUG RESISTANCE-RELATED P-GLYCOPROTEIN BY CA2-CALMODULIN()
Authors: SCHLEMMER SR YANG CH SIROTNAK FM
Citation: Sr. Schlemmer et al., FUNCTIONAL MODULATION OF MULTIDRUG RESISTANCE-RELATED P-GLYCOPROTEIN BY CA2-CALMODULIN(), The Journal of biological chemistry, 270(19), 1995, pp. 11040-11042
RAPID DECLINE IN FOLYLPOLYGLUTAMATE SYNTHETASE-ACTIVITY AND GENE-EXPRESSION DURING MATURATION OF HL-60 CELLS - NATURE OF THE EFFECT, IMPACTON FOLATE COMPOUND POLYGLUTAMATE POOLS, AND EVIDENCE FOR PROGRAMMED DOWN-REGULATION DURING MATURATION
Authors: EGAN MG SIRLIN S RUMBERGER BG GARROW TA SHANE B SIROTNAK FM
Citation: Mg. Egan et al., RAPID DECLINE IN FOLYLPOLYGLUTAMATE SYNTHETASE-ACTIVITY AND GENE-EXPRESSION DURING MATURATION OF HL-60 CELLS - NATURE OF THE EFFECT, IMPACTON FOLATE COMPOUND POLYGLUTAMATE POOLS, AND EVIDENCE FOR PROGRAMMED DOWN-REGULATION DURING MATURATION, The Journal of biological chemistry, 270(10), 1995, pp. 5462-5468
STRUCTURAL PREFERENCES AMONG FOLATE COMPOUNDS AND THEIR ANALOGS FOR ATPASE-MEDIATED EFFLUX BY INSIDE-OUT PLASMA-MEMBRANE VESICLES DERIVED FROM L1210 CELLS
Authors: SCHLEMMER SR SIROTNAK FM
Citation: Sr. Schlemmer et Fm. Sirotnak, STRUCTURAL PREFERENCES AMONG FOLATE COMPOUNDS AND THEIR ANALOGS FOR ATPASE-MEDIATED EFFLUX BY INSIDE-OUT PLASMA-MEMBRANE VESICLES DERIVED FROM L1210 CELLS, Biochemical pharmacology, 49(10), 1995, pp. 1427-1433
FACILE PREPARATION OF INSIDE-OUT PLASMA-MEMBRANE VESICLES FROM TUMOR-CELLS FOR FUNCTIONAL-STUDIES OF PHARMACOLOGICALLY RELEVANT TRANSLOCATING ATPASES
Authors: SCHLEMMER SR SIROTNAK FM
Citation: Sr. Schlemmer et Fm. Sirotnak, FACILE PREPARATION OF INSIDE-OUT PLASMA-MEMBRANE VESICLES FROM TUMOR-CELLS FOR FUNCTIONAL-STUDIES OF PHARMACOLOGICALLY RELEVANT TRANSLOCATING ATPASES, Analytical biochemistry, 228(2), 1995, pp. 226-231
Risultati: 1-25 | 26-34