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Results: 1-5 |
Results: 5
ANTIVIRAL ACTIVITY OF THE DIHYDROPYRONE PNU-140690, A NEW NONPEPTIDICHUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE INHIBITOR
Authors: POPPE SM SLADE DE CHONG KT HINSHAW RR PAGANO PJ MARKOWITZ M HO DD MO H GORMAN RR DUEWEKE TJ THAISRIVONGS S TARPLEY WG
Citation: Sm. Poppe et al., ANTIVIRAL ACTIVITY OF THE DIHYDROPYRONE PNU-140690, A NEW NONPEPTIDICHUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE INHIBITOR, Antimicrobial agents and chemotherapy, 41(5), 1997, pp. 1058-1063
(ALKYLAMINO)PIPERIDINE BIS(HETEROARYL)PIPERIZINE ANALOGS ARE POTENT, BROAD-SPECTRUM NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITORS OF DRUG-RESISTANT ISOLATES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) AND SELECT FOR DRUG-RESISTANT VARIANTS OF HIV-1(IIIB) WITH REDUCED REPLICATION PHENOTYPES
Authors: OLMSTED RA SLADE DE KOPTA LA POPPE SM POEL TJ NEWPORT SW RANK KB BILES C MORGE RA DUEWEKE TJ YAGI Y ROMERO DL THOMAS RC SHARMA SK TARPLEY WG
Citation: Ra. Olmsted et al., (ALKYLAMINO)PIPERIDINE BIS(HETEROARYL)PIPERIZINE ANALOGS ARE POTENT, BROAD-SPECTRUM NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITORS OF DRUG-RESISTANT ISOLATES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) AND SELECT FOR DRUG-RESISTANT VARIANTS OF HIV-1(IIIB) WITH REDUCED REPLICATION PHENOTYPES, Journal of virology, 70(6), 1996, pp. 3698-3705
STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S SKULNICK HI TURNER SR STROHBACH JW TOMMASI RA JOHNSON PD ARISTOFF PA JUDGE TM GAMMILL RB MORRIS JK ROMINES KR CHRUSCIEL RA HINSHAW RR CHONG KT TARPLEY WG POPPE SM SLADE DE LYNN JC HORNG MM TOMICH PK SEEST EP DOLAK LA HOWE WJ HOWARD GM SCHWENDE FJ TOTH LN PADBURY GE WILSON GJ SHIOU LH ZIPP GL WILKINSON KF RUSH BD RUWART MJ KOEPLINGER KA ZHAO ZY COLE S ZAYA RM KAKUK TJ JANAKIRAMAN MN WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(22), 1996, pp. 4349-4353
A DRUG-RESISTANCE MUTATION IN THE INHIBITOR BINDING POCKET OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE IMPAIRS DNA-SYNTHESIS AND RNA DEGRADATION
Authors: FAN NS RANK KB SLADE DE POPPE SM EVANS DB KOPTA LA OLMSTED RA THOMAS RC TARPLEY WG SHARMA SK
Citation: Ns. Fan et al., A DRUG-RESISTANCE MUTATION IN THE INHIBITOR BINDING POCKET OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE IMPAIRS DNA-SYNTHESIS AND RNA DEGRADATION, Biochemistry, 35(30), 1996, pp. 9737-9745
A DRUG-RESISTANCE MUTATION (G190E) IN THE INHIBITOR BINDING POCKET IMPAIRS BOTH RNA-DEPENDENT DNA-POLYMERASE AND RIBONUCLEASE-H ACTIVITIES OF HIV-1 REVERSE-TRANSCRIPTASE
Authors: SHARMA SK FAN N RANK KB KOPTA LA OLMSTED RA POPPE SM SLADE DE THOMAS RC TARPLEY WG
Citation: Sk. Sharma et al., A DRUG-RESISTANCE MUTATION (G190E) IN THE INHIBITOR BINDING POCKET IMPAIRS BOTH RNA-DEPENDENT DNA-POLYMERASE AND RIBONUCLEASE-H ACTIVITIES OF HIV-1 REVERSE-TRANSCRIPTASE, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 2-2
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