Authors:
SCHINKEL AH
MAYER U
WAGENAAR E
MOL CAAM
VANDEEMTER L
SMIT JJM
VANDERVALK MA
VOORDOUW AC
SPITS H
VANTELLINGEN O
ZIJLMANS JMJM
FIBBE WE
BORST P
Citation: Ah. Schinkel et al., NORMAL VIABILITY AND ALTERED PHARMACOKINETICS IN MICE LACKING MDR1-TYPE (DRUG-TRANSPORTING) P-GLYCOPROTEINS, Proceedings of the National Academy of Sciences of the United Statesof America, 94(8), 1997, pp. 4028-4033
Authors:
SMIT JJM
BASS F
HOOGENDIJK JE
JANSEN GH
VANDERVALK MA
SCHINKEL AH
BERNS AJM
ACTON D
NOOTER K
BURGER H
SMITH SJ
BORST P
Citation: Jjm. Smit et al., PERIPHERAL NEUROPATHY IN MICE TRANSGENIC FOR A HUMAN MDR3 P-GLYCOPROTEIN MINI-GENE, The Journal of neuroscience, 16(20), 1996, pp. 6386-6393
Authors:
DUNIA I
SMIT JJM
VANDERVALK MA
BLOEMENDAL H
BORST P
BENEDETTI EL
Citation: I. Dunia et al., HUMAN MULTIDRUG-RESISTANCE 3-P-GLYCOPROTEIN EXPRESSION IN TRANSGENIC MICE INDUCES LENS MEMBRANE-ALTERATIONS LEADING TO CATARACT, The Journal of cell biology, 132(4), 1996, pp. 701-716
Authors:
SCHINKEL AH
MOL CAAM
WAGENAAR E
VANDEEMTER L
SMIT JJM
BORST P
Citation: Ah. Schinkel et al., MULTIDRUG-RESISTANCE AND THE ROLE OF P-GLYCOPROTEIN KNOCKOUT MICE, European journal of cancer, 31A(7-8), 1995, pp. 1295-1298
Citation: Mjj. Vanhaaren et al., A COMBINATION OF SITE-SPECIFIC RECOMBINATION AND TRANSPOSITION FOR THE INDUCTION OF CHROMOSOMAL REARRANGEMENTS IN TRANSGENIC TOMATO PLANTS, Journal of cellular biochemistry, 1995, pp. 159-159
Authors:
SMIT JJM
MOL CAAM
VANDEEMTER L
WAGENAAR E
SCHINKEL AH
BORST P
Citation: Jjm. Smit et al., CHARACTERIZATION OF THE PROMOTER REGION OF THE HUMAN MDR3 P-GLYCOPROTEIN GENE, Biochimica et biophysica acta, N. Gene structure and expression, 1261(1), 1995, pp. 44-56
Authors:
ELFERINK RPJO
OTTENHOFF R
VANWIJLAND M
SMIT JJM
SCHINKEL AH
GROEN AK
Citation: Rpjo. Elferink et al., REGULATION OF BILIARY LIPID SECRETION BY MDR2 P-GLYCOPROTEIN IN THE MOUSE, The Journal of clinical investigation, 95(1), 1995, pp. 31-38
Citation: Ak. Groen et al., REGULATION OF PROTEIN SECRETION INTO BILE - STUDIES IN MICE WITH A DISRUPTED MDR2 P-GLYCOPROTEIN GENE, Gastroenterology, 109(6), 1995, pp. 1997-2006
Authors:
SCHINKEL AH
SMIT JJM
VANTELLINGEN O
BEIJNEN JH
WAGENAAR E
VANDEEMTER L
MOL CAAM
VANDERVALK MA
ROBANUSMAANDAG EC
TERIELE HPJ
BERNS AJM
BORST P
Citation: Ah. Schinkel et al., DISRUPTION OF THE MOUSE MDR1A P-GLYCOPROTEIN GENE LEADS TO A DEFICIENCY IN THE BLOOD-BRAIN-BARRIER AND TO INCREASED SENSITIVITY TO DRUGS, Cell, 77(4), 1994, pp. 491-502
Authors:
SMITH AJ
TIMMERMANSHEREIJGERS JLPM
ROELOFSEN B
WIRTZ KWA
VANBLITTERSWIJK WJ
SMIT JJM
SCHINKEL AH
BORST P
Citation: Aj. Smith et al., THE HUMAN MDR3 P-GLYCOPROTEIN PROMOTES TRANSLOCATION OF PHOSPHATIDYLCHOLINE THROUGH THE PLASMA-MEMBRANE OF FIBROBLASTS FROM TRANSGENIC MICE, FEBS letters, 354(3), 1994, pp. 263-266
Authors:
KUIPERS F
SMIT JJM
ELFERINK RPJO
OTTENHOF R
SCHINKEL AH
VERKADE HJ
VONK RJ
BORST P
GROEN AK
Citation: F. Kuipers et al., THE ROLE OF BILIARY CHOLESTEROL AND PHOSPHOLIPIDS IN THE REGULATION OF PLASMA-LIPID LEVELS - STUDIES IN MDR2 TRANSGENIC MICE, Circulation, 90(4), 1994, pp. 352-352
Authors:
KUIPERS F
SMIT JJM
ELFERINK RPJO
OTTENHOF R
SCHINKEL AH
VERKADE HJ
VONK RJ
BORST P
GROEN AK
Citation: F. Kuipers et al., THE ROLE OF BILIARY CHOLESTEROL AND PHOSPHOLIPIDS IN THE REGULATION OF PLASMA-LIPID LEVELS - STUDIES IN MDR2 TRANSGENIC MICE, Circulation, 90(4), 1994, pp. 352-352
Authors:
MAUAD TH
VANNIEUWKERK CMJ
DINGEMANS KP
SMIT JJM
SCHINKEL AH
NOTENBOOM RGE
WEERMAN MAV
VERKRUISEN RP
GROEN AK
ELFERINK RPJO
VANDERVALK MA
BORST P
OFFERHAUS GJA
Citation: Th. Mauad et al., MICE WITH HOMOZYGOUS DISRUPTION OF THE MDR2 P-GLYCOPROTEIN GENE - A NOVEL ANIMAL-MODEL FOR STUDIES OF NONSUPPURATIVE INFLAMMATORY CHOLANGITIS AND HEPATOCARCINOGENESIS, The American journal of pathology, 145(5), 1994, pp. 1237-1245
Authors:
SMIT JJM
SCHINKEL AH
ELFERINK RPJO
GROEN AK
WAGENAAR E
VANDEEMTER L
MOL CAAM
OTTENHOFF R
VANDERLUGT NMT
VANROON M
VANDERVALK MA
OFFERHAUS GJA
BERNS AJM
BORST P
Citation: Jjm. Smit et al., HOMOZYGOUS DISRUPTION OF THE MURINE MDR2 P-GLYCOPROTEIN GENE LEADS TOLIVER-DISEASE, Hepatology, 18(4), 1993, pp. 10000142-10000142
Authors:
BORST P
SCHINKEL AH
SMIT JJM
WAGENAAR E
VANDEEMTER L
SMITH AJ
EIJDEMS EWHM
BAAS F
ZAMAN GJR
Citation: P. Borst et al., CLASSICAL AND NOVEL FORMS OF MULTIDRUG-RESISTANCE AND THE PHYSIOLOGICAL FUNCTIONS OF P-GLYCOPROTEINS IN MAMMALS, Pharmacology & therapeutics, 60(2), 1993, pp. 289-299
Authors:
SMIT JJM
SCHINKEL AH
ELFERINK RPJO
GROEN AK
WAGENAAR E
VANDEEMTER L
MOL CAAM
OTTENHOFF R
VANDERLUGT NMT
VANROON MA
VANDERVALK MA
OFFERHAUS GJA
BERNS AJM
BORST P
Citation: Jjm. Smit et al., HOMOZYGOUS DISRUPTION OF THE MURINE MDR2 P-GLYCOPROTEIN GENE LEADS TOA COMPLETE ABSENCE OF PHOSPHOLIPID FROM BILE AND TO LIVER-DISEASE, Cell, 75(3), 1993, pp. 451-462
Authors:
SCHINKEL AH
ARCECI RJ
SMIT JJM
WAGENAAR E
BAAS F
DOLLE M
TSURUO T
MECHETNER EB
RONINSON IB
BORST P
Citation: Ah. Schinkel et al., BINDING-PROPERTIES OF MONOCLONAL-ANTIBODIES RECOGNIZING EXTERNAL EPITOPES OF THE HUMAN MDR1 P-GLYCOPROTEIN, International journal of cancer, 55(3), 1993, pp. 478-484
Authors:
ZAMAN GJR
VERSANTVOORT CHM
SMIT JJM
EIJDEMS EWHM
DEHAAS M
SMITH AJ
BROXTERMAN HJ
MULDER NH
DEVRIES EGE
BAAS F
BORST P
Citation: Gjr. Zaman et al., ANALYSIS OF THE EXPRESSION OF MRP, THE GENE FOR A NEW PUTATIVE TRANSMEMBRANE DRUG TRANSPORTER, IN HUMAN MULTIDRUG RESISTANT LUNG-CANCER CELL-LINES, Cancer research, 53(8), 1993, pp. 1747-1750