Authors:
SPARREBOOM A
DEBRUIJN P
DEJONGE MJA
LOOS WJ
STOTER G
VERWEIJ J
NOOTER K
Citation: A. Sparreboom et al., LIQUID-CHROMATOGRAPHIC DETERMINATION OF IRINOTECAN AND 3 MAJOR METABOLITES IN HUMAN PLASMA, URINE AND FECES, Journal of chromatography B. Biomedical sciences and applications, 712(1-2), 1998, pp. 225-235
Authors:
SPARREBOOM A
DEBRUIJN P
NOOTER K
LOOS WJ
STOTER G
VERWEIJ J
Citation: A. Sparreboom et al., DETERMINATION OF PACLITAXEL IN HUMAN PLASMA USING SINGLE SOLVENT-EXTRACTION PRIOR TO ISOCRATIC REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ULTRAVIOLET DETECTION, Journal of chromatography B. Biomedical sciences and applications, 705(1), 1998, pp. 159-164
Authors:
SPARREBOOM A
DEJONGE MJA
PUNT CJA
NOOTER K
LOOS WJ
PORRO MG
VERWEIJ J
Citation: A. Sparreboom et al., PHARMACOKINETICS AND BIOAVAILABILITY OF ORAL 9-AMINOCAMPTOTHECIN CAPSULES IN ADULT PATIENTS WITH SOLID TUMORS, Clinical cancer research, 4(8), 1998, pp. 1915-1919
Authors:
SPARREBOOM A
VERWEIJ J
VANDERBURG MEL
LOOS WJ
BROUWER E
VIGANO L
LOCATELLI A
DEVOS AI
NOOTER K
STOTER G
GIANNI L
Citation: A. Sparreboom et al., DISPOSITION OF CREMOPHOR EL IN HUMANS LIMITS THE POTENTIAL FOR MODULATION OF THE MULTIDRUG-RESISTANCE PHENOTYPE IN-VIVO, Clinical cancer research, 4(8), 1998, pp. 1937-1942
Authors:
SPARREBOOM A
DEJONGE MJA
DEBRUIJN P
BROUWER E
NOOTER K
LOOS WJ
VANALPHEN RJ
MATHIJSSEN RHJ
STOTER G
VERWEIJ J
Citation: A. Sparreboom et al., IRINOTECAN (CPT-11) METABOLISM AND DISPOSITION IN CANCER-PATIENTS, Clinical cancer research, 4(11), 1998, pp. 2747-2754
Authors:
SPARREBOOM A
DEBRUIJN P
DEJONGE MJA
LOOS WJ
NOOTER K
STOTER G
VERWEIJ J
Citation: A. Sparreboom et al., LIQUID-CHROMATOGRAPHIC DETERMINATION OF IRINOTECAN (CPT-11) AND ITS MAJOR METABOLITES IN HUMAN PLASMA, URINE AND FECES, Annals of oncology, 9, 1998, pp. 219-219
Authors:
SPARREBOOM A
DEJONGE MJA
PUNT CJA
LOOS WJ
DALLAIRE BK
VERWEIJ J
Citation: A. Sparreboom et al., LIMITED-SAMPLING MODELS FOR 9-AMINOCAMPTOTHECIN PHARMACOKINETICS AFTER ORAL-DRUG ADMINISTRATION, Annals of oncology, 9, 1998, pp. 228-228
Authors:
SPARREBOOM A
DEJONGE MJA
PUNT CJA
LOOS WJ
DALLAIRE BK
VERWEIJ J
Citation: A. Sparreboom et al., CLINICAL PHARMACOKINETICS OF ORAL 9-AMINOCAMPTOTHECIN IN PLASMA AND SALIVA - RELATIONSHIPS WITH HEMATOLOGIC TOXICITY, Annals of oncology, 9, 1998, pp. 229-229
Authors:
DEJONGE MJA
PUNT CJA
SPARREBOOM A
LOOS WJ
VANBEURDEN V
PLANTING AST
DALLAIRE B
VERWEIJ J
Citation: Mja. Dejonge et al., PHASE-I AND PHARMACOLOGICAL STUDY ON ORAL [PEG-1000] 9-AMINO-CAMPTOTHECIN (9-AC) IN PATIENTS WITH ADVANCED SOLID TUMORS, Annals of oncology, 9, 1998, pp. 243-243
Authors:
DEJONGE MJA
SPARREBOOM A
PLANTING AST
VANDERBURG MEL
DEBOERDENNERT MM
DEBRUYN P
JACQUES C
VERWEIJ J
Citation: Mja. Dejonge et al., PHASE-I TRIAL OF IRINOTECAN (CPT-11) COMBINED WITH CISPLATIN (C) GIVEN ONCE EVERY 3 WEEKS TO PATIENTS WITH SOLID TUMORS, Annals of oncology, 9, 1998, pp. 259-259
Authors:
DEJONGE MJA
SPARREBOOM A
PLANTING AST
BROUWER E
VANDERBURG MEL
HEARN S
VERWEIJ J
Citation: Mja. Dejonge et al., ORAL TOPOTECAN (T) ON A DAILY X 5 SCHEDULE IN COMBINATION WITH INTRAVENOUS CISPLATIN (C) - A PHASE-I AND PHARMACOLOGICAL STUDY IN PATIENTS WITH ADVANCED SOLID TUMORS, Annals of oncology, 9, 1998, pp. 264-264
Authors:
SPARREBOOM A
LOOS WJ
BROUWER E
NOOTER K
STOTER G
VERWEIJ J
Citation: A. Sparreboom et al., A RAPID COLORIMETRIC DYE-BINDING MICROASSAY FOR QUANTITATION OF THE PACLITAXEL VEHICLE CREMOPHOR EL, Annals of oncology, 9, 1998, pp. 503-503
Authors:
SPARREBOOM A
PLANTING AST
JEWELL RC
PAUL EM
WISSEL PS
DEBRUIJN P
NOOTER K
STOTER G
VERWEIJ J
Citation: A. Sparreboom et al., CLINICAL PHARMACOKINETICS OF DOXORUBICIN IN COMBINATION WITH GF120918, A POTENT INHIBITOR OF MDR1 P-GLYCOPROTEIN, Annals of oncology, 9, 1998, pp. 550-550
Authors:
SPARREBOOM A
VERWEIJ J
VANDERBURG MEL
LOOS WJ
VIGANO L
LOCATELLI A
NOOTER K
STOTER G
GIANNI L
Citation: A. Sparreboom et al., DISPOSITION OF CREMOPHOR EL IN HUMANS LIMITS THE POTENTIAL FOR MODULATION OF THE MULTIDRUG-RESISTANCE PHENOTYPE IN-VIVO, Annals of oncology, 9, 1998, pp. 551-551
Citation: Mja. Dejonge et al., THE DEVELOPMENT OF COMBINATION THERAPY INVOLVING CAMPTOTHECINS - A REVIEW OF PRECLINICAL AND EARLY CLINICAL-STUDIES, Cancer treatment reviews, 24(3), 1998, pp. 205-220
Authors:
BROUWER E
VERWEIJ J
HAUNS B
LOOS WJ
NOOTER E
MROSS K
STOTER G
SPARREBOOM A
Citation: E. Brouwer et al., LINEARIZED COLORIMETRIC ASSAY FOR CREMOPHOR EL - APPLICATION TO PHARMACOKINETICS AFTER 1-HOUR PACLITAXEL INFUSIONS, Analytical biochemistry (Print), 261(2), 1998, pp. 198-202
Authors:
SPARREBOOM A
LOOS WJ
VERWEIJ J
DEVOS AI
VANDERBURG MEL
STOTER G
NOOTER K
Citation: A. Sparreboom et al., QUANTITATION OF CREMOPHOR EL IN HUMAN PLASMA SAMPLES USING A COLORIMETRIC DYE-BINDING MICROASSAY, Analytical biochemistry, 255(2), 1998, pp. 171-175
Authors:
DEBRUIJN P
VERWEIJ J
LOOS WJ
NOOTER K
STOTER G
SPARREBOOM A
Citation: P. Debruijn et al., DETERMINATION OF IRINOTECAN (CPT-11) AND ITS ACTIVE METABOLITE SN-38 IN HUMAN PLASMA BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH FLUORESCENCE DETECTION, Journal of chromatography B. Biomedical sciences and applications, 698(1-2), 1997, pp. 277-285
Authors:
LOOS WJ
SPARREBOOM A
VERWEIJ J
NOOTER K
STOTER G
SCHELLENS JHM
Citation: Wj. Loos et al., DETERMINATION OF THE LACTONE AND LACTONE PLUS CARBOXYLATE FORMS OF 9-AMINOCAMPTOTHECIN IN HUMAN PLASMA BY SENSITIVE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH FLUORESCENCE DETECTION, Journal of chromatography B. Biomedical sciences and applications, 694(2), 1997, pp. 435-441
Authors:
LOOS WJ
VERWEIJ J
NOOTER K
STOTER G
SPARREBOOM A
Citation: Wj. Loos et al., SENSITIVE DETERMINATION OF DOCETAXEL IN HUMAN PLASMA BY LIQUID-LIQUID-EXTRACTION AND REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Journal of chromatography B. Biomedical sciences and applications, 693(2), 1997, pp. 437-441
Authors:
VASEY PA
PRONK L
TWELVES C
SPARREBOOM A
WILSON P
GORDON RJ
OSTERWALDER B
VERWEIJ J
Citation: Pa. Vasey et al., PHASE-I AND PHARMACOKINETIC STUDY OF XELODA(TM) (CAPECITABINE) IN COMBINATION WITH DOCETAXEL, European journal of cancer, 33, 1997, pp. 1113-1113
Authors:
DEJONGE MJA
SPARREBOOM A
PLANTING AST
VANDERBURG MEL
DEBRUIJN P
BROUWER E
VANBEURDEN V
VANDUIJN MR
JACQUES C
VERWEIJ J
Citation: Mja. Dejonge et al., PHASE-I AND PHARMACOKINETIC (PK) STUDY OF IRINOTECAN (CPT-11) AND CISPLATIN IN PATIENTS WITH SOLID TUMORS - PRELIMINARY-RESULTS, European journal of cancer, 33, 1997, pp. 1134-1134
Authors:
DEVOS AI
NOOTER K
VERWEIJ J
LOOS WL
BROUWER E
DEBRUIJN P
RUIJGROK EJ
VANDERBURG MEL
STOTER G
SPARREBOOM A
Citation: Ai. Devos et al., DIFFERENTIAL MODULATION OF CISPLATIN ACCUMULATION IN LEUKOCYTES AND TUMOR-CELL LINES BY THE PACLITAXEL VEHICLE CREMOPHOR EL, Annals of oncology, 8(11), 1997, pp. 1145-1150
Authors:
SPARREBOOM A
VANASPEREN J
MAYER U
SCHINKEL AH
SMIT JW
MEIJER DKF
BORST P
NOOIJEN WJ
BEIJNEN JH
VANTELLINGEN O
Citation: A. Sparreboom et al., LIMITED ORAL BIOAVAILABILITY AND ACTIVE EPITHELIAL EXCRETION OF PACLITAXEL (TAXOL) CAUSED BY P-GLYCOPROTEIN IN THE INTESTINE, Proceedings of the National Academy of Sciences of the United Statesof America, 94(5), 1997, pp. 2031-2035