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Results: 1-16 |
Results: 16
A STRUCTURAL ROLE FOR GLUTAMINE-214 IN HUMAN THYMIDYLATE SYNTHASE
Authors: STEADMAN DJ ZHAO PS SPENCER HT DUNLAP RB BERGER SH
Citation: Dj. Steadman et al., A STRUCTURAL ROLE FOR GLUTAMINE-214 IN HUMAN THYMIDYLATE SYNTHASE, Biochemistry, 37(20), 1998, pp. 7089-7095
RETROVIRAL COEXPRESSION OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE-REDUCTASE CONFERS FLUOROPYRIMIDINE AND ANTIFOLATE RESISTANCE
Authors: FANTZ CR SHAW D MOORE JG SPENCER HT
Citation: Cr. Fantz et al., RETROVIRAL COEXPRESSION OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE-REDUCTASE CONFERS FLUOROPYRIMIDINE AND ANTIFOLATE RESISTANCE, Biochemical and biophysical research communications, 243(1), 1998, pp. 6-12
COMPARISON OF THE PROTECTION OF CELLS FROM ANTIFOLATES BY TRANSDUCED HUMAN DIHYDROFOLATE-REDUCTASE MUTANTS
Authors: PATEL M SLEEP SEH LEWIS WS SPENCER HT MAREYA SM SORRENTINO BP BLAKLEY RL
Citation: M. Patel et al., COMPARISON OF THE PROTECTION OF CELLS FROM ANTIFOLATES BY TRANSDUCED HUMAN DIHYDROFOLATE-REDUCTASE MUTANTS, Human gene therapy, 8(17), 1997, pp. 2069-2077
A BICISTRONIC RETROVIRAL VECTOR FOR PROTECTING HEMATOPOIETIC-CELLS AGAINST ANTIFOLATES AND P-GLYCOPROTEIN EFFLUXED DRUGS
Authors: GALIPEAU J BENAIM E SPENCER HT BLAKLEY RL SORRENTINO BP
Citation: J. Galipeau et al., A BICISTRONIC RETROVIRAL VECTOR FOR PROTECTING HEMATOPOIETIC-CELLS AGAINST ANTIFOLATES AND P-GLYCOPROTEIN EFFLUXED DRUGS, Human gene therapy, 8(15), 1997, pp. 1773-1783
SENSITIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS TO TRIMETREXATE USING NUCLEOSIDE TRANSPORT INHIBITORS
Authors: ALLAY JA SPENCER HT WILKINSON SL BELT JA BLAKLEY RL SORRENTINO BP
Citation: Ja. Allay et al., SENSITIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS TO TRIMETREXATE USING NUCLEOSIDE TRANSPORT INHIBITORS, Blood, 90(9), 1997, pp. 3546-3554
RETROVIRAL GENE-TRANSFER OF A THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE CHIMERA CONFERS FLUOROPYRIMIDINE AND ANTIFOLATE RESISTANCE
Authors: FANTZ C SPENCER HT
Citation: C. Fantz et Ht. Spencer, RETROVIRAL GENE-TRANSFER OF A THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE CHIMERA CONFERS FLUOROPYRIMIDINE AND ANTIFOLATE RESISTANCE, Blood, 90(10), 1997, pp. 4599-4599
KINETIC SCHEME FOR THYMIDYLATE SYNTHASE FROM ESCHERICHIA-COLI - DETERMINATION FROM MEASUREMENTS OF LIGAND-BINDING, PRIMARY AND SECONDARY ISOTOPE EFFECTS, AND PRE-STEADY-STATE CATALYSIS
Authors: SPENCER HT VILLAFRANCA JE APPLEMAN JR
Citation: Ht. Spencer et al., KINETIC SCHEME FOR THYMIDYLATE SYNTHASE FROM ESCHERICHIA-COLI - DETERMINATION FROM MEASUREMENTS OF LIGAND-BINDING, PRIMARY AND SECONDARY ISOTOPE EFFECTS, AND PRE-STEADY-STATE CATALYSIS, Biochemistry, 36(14), 1997, pp. 4212-4222
MUTATIONS IN THE GENE FOR HUMAN DIHYDROFOLATE-REDUCTASE - AN UNLIKELYCAUSE OF CLINICAL RELAPSE IN PEDIATRIC LEUKEMIA AFTER THERAPY WITH METHOTREXATE
Authors: SPENCER HT SORRENTINO BP PUI CH CHUNDURU SK SLEEP SEH BLAKLEY RL
Citation: Ht. Spencer et al., MUTATIONS IN THE GENE FOR HUMAN DIHYDROFOLATE-REDUCTASE - AN UNLIKELYCAUSE OF CLINICAL RELAPSE IN PEDIATRIC LEUKEMIA AFTER THERAPY WITH METHOTREXATE, Leukemia, 10(3), 1996, pp. 439-446
PROTECTION OF HEMATOPOIETIC-CELLS FROM ANTIFOLATE TOXICITY BY A NOVELVARIANT OF HUMAN DIHYDROFOLATE-REDUCTASE
Authors: SORRENTINO BP SPENCER HT BLAKLEY RL ALLAY JA
Citation: Bp. Sorrentino et al., PROTECTION OF HEMATOPOIETIC-CELLS FROM ANTIFOLATE TOXICITY BY A NOVELVARIANT OF HUMAN DIHYDROFOLATE-REDUCTASE, Experimental hematology, 24(9), 1996, pp. 730-730
IN-VIVO SELECTION OF DHFR-MODIFIED MURINE HEMATOPOIETIC PROGENITORS BY COMBINED TREATMENT WITH TRIMETREXATE AND THYMIDINE TRANSPORT INHIBITORS
Authors: ALLAY JA SPENCER HT WILKINSON SL BELL JA BLAKLEY RL SORRENTINO BP
Citation: Ja. Allay et al., IN-VIVO SELECTION OF DHFR-MODIFIED MURINE HEMATOPOIETIC PROGENITORS BY COMBINED TREATMENT WITH TRIMETREXATE AND THYMIDINE TRANSPORT INHIBITORS, Blood, 88(10), 1996, pp. 2568-2568
A BICISTRONIC RETROVIRAL VECTOR FOR PROTECTING HEMATOPOIETIC-CELLS AGAINST ANTI-FOLATES AND MDR1-EFFLUXED DRUGS
Authors: GALIPEAU J BENAIM E SPENCER HT BLAKLEY RL SORRENTINO BP
Citation: J. Galipeau et al., A BICISTRONIC RETROVIRAL VECTOR FOR PROTECTING HEMATOPOIETIC-CELLS AGAINST ANTI-FOLATES AND MDR1-EFFLUXED DRUGS, Blood, 88(10), 1996, pp. 2569-2569
A GENE-TRANSFER STRATEGY FOR MAKING BONE-MARROW CELLS RESISTANT TO TRIMETREXATE
Authors: SPENCER HT SLEEP SEH REHG JE BLAKLEY RL SORRENTINO BP
Citation: Ht. Spencer et al., A GENE-TRANSFER STRATEGY FOR MAKING BONE-MARROW CELLS RESISTANT TO TRIMETREXATE, Blood, 87(6), 1996, pp. 2579-2587
METHOTREXATE-RESISTANT VARIANTS OF HUMAN DIHYDROFOLATE-REDUCTASE WITHSUBSTITUTIONS OF LEUCINE-22 - KINETICS, CRYSTALLOGRAPHY, AND POTENTIAL AS SELECTABLE MARKERS
Authors: LEWIS WS CODY V GALITSKY N LUFT JR PANGBORN W CHUNDURU SK SPENCER HT APPLEMAN JR BLAKLEY RL
Citation: Ws. Lewis et al., METHOTREXATE-RESISTANT VARIANTS OF HUMAN DIHYDROFOLATE-REDUCTASE WITHSUBSTITUTIONS OF LEUCINE-22 - KINETICS, CRYSTALLOGRAPHY, AND POTENTIAL AS SELECTABLE MARKERS, The Journal of biological chemistry, 270(10), 1995, pp. 5057-5064
PROTECTION OF MICE FROM TRIMETREXATE-INDUCED MYELOSUPPRESSION BY TRANSFER OF A TYR22 DIHYDROFOLATE-REDUCTASE GENE
Authors: SPENCER HT BLAKLEY RL SORRENTINO BP
Citation: Ht. Spencer et al., PROTECTION OF MICE FROM TRIMETREXATE-INDUCED MYELOSUPPRESSION BY TRANSFER OF A TYR22 DIHYDROFOLATE-REDUCTASE GENE, Blood, 86(10), 1995, pp. 1847-1847
GENERATION OF METHOTREXATE-RESISTANT HEMATOPOIETIC PROGENITOR CELLS BY RETROVIRAL TRANSFER OF CDNAS ENCODING NOVEL VARIANTS OF HUMAN DIHYDROFOLATE-REDUCTASE
Authors: SPENCER HT LEWIS WS CHUNDURU SK BLAKLEY RL SORRENTINO BP
Citation: Ht. Spencer et al., GENERATION OF METHOTREXATE-RESISTANT HEMATOPOIETIC PROGENITOR CELLS BY RETROVIRAL TRANSFER OF CDNAS ENCODING NOVEL VARIANTS OF HUMAN DIHYDROFOLATE-REDUCTASE, Blood, 84(10), 1994, pp. 10000401-10000401
CRITICAL ROLE OF PHENYLALANINE-34 OF HUMAN DIHYDROFOLATE-REDUCTASE INSUBSTRATE AND INHIBITOR BINDING AND IN CATALYSIS
Authors: NAKANO T SPENCER HT APPLEMAN JR BLAKLEY RL
Citation: T. Nakano et al., CRITICAL ROLE OF PHENYLALANINE-34 OF HUMAN DIHYDROFOLATE-REDUCTASE INSUBSTRATE AND INHIBITOR BINDING AND IN CATALYSIS, Biochemistry, 33(33), 1994, pp. 9945-9952
Risultati: 1-16 |