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Results: 1-25 | 26-46
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NEURAL ACTIONS OF IMMUNOPHILIN LIGANDS
Authors: SNYDER SH SABATINI DM LAI MM STEINER JP HAMILTON GS SUZDAK PD
Citation: Sh. Snyder et al., NEURAL ACTIONS OF IMMUNOPHILIN LIGANDS, Trends in pharmacological sciences, 19(1), 1998, pp. 21-26
FKBP12-BINDING DOMAIN ANALOGS OF FK506 ARE POTENT, NONIMMUNOSUPPRESSIVE NEUROTROPHIC AGENTS IN-VITRO AND PROMOTE RECOVERY IN A MOUSE MODEL OF PARKINSONS-DISEASE
Authors: HAMILTON GS HUANG W CONNOLLY MA ROSS DT GUO H VALENTINE HL SUZDAK PD STEINER JP
Citation: Gs. Hamilton et al., FKBP12-BINDING DOMAIN ANALOGS OF FK506 ARE POTENT, NONIMMUNOSUPPRESSIVE NEUROTROPHIC AGENTS IN-VITRO AND PROMOTE RECOVERY IN A MOUSE MODEL OF PARKINSONS-DISEASE, Bioorganic & medicinal chemistry letters, 7(13), 1997, pp. 1785-1790
XANOMELINE - A SELECTIVE MUSCARINIC AGONIST FOR THE TREATMENT OF ALZHEIMERS-DISEASE
Authors: BYMASTER FP WHITESITT CA SHANNON HE DELAPP N WARD JS CALLIGARO DO SHIPLEY LA BUELKESAM JL BODICK NC FARDE L SHEARDOWN MJ OLESEN PH HANSEN KT SUZDAK PD SWEDBERG MDB SAUERBERG P MITCH CH
Citation: Fp. Bymaster et al., XANOMELINE - A SELECTIVE MUSCARINIC AGONIST FOR THE TREATMENT OF ALZHEIMERS-DISEASE, Drug development research, 40(2), 1997, pp. 158-170
ORALLY-ACTIVE NEUROIMMUNOPHILIN LIGANDS PROMOTE RECOVERY FROM DOPAMINERGIC LESIONS IN ANIMAL-MODELS OF PARKINSONS-DISEASE
Authors: STEINER JP HAMILTON GS ROSS DT SAUER H SUZDAK PD
Citation: Jp. Steiner et al., ORALLY-ACTIVE NEUROIMMUNOPHILIN LIGANDS PROMOTE RECOVERY FROM DOPAMINERGIC LESIONS IN ANIMAL-MODELS OF PARKINSONS-DISEASE, Neurology, 48(3), 1997, pp. 5124-5124
NEUROTROPHIC IMMUNOPHILIN LIGANDS STIMULATE STRUCTURAL AND FUNCTIONALRECOVERY IN NEURODEGENERATIVE ANIMAL-MODELS
Authors: STEINER JP HAMILTON GS ROSS DT VALENTINE HL GUO HZ CONNOLLY MA LIANG S RAMSEY C LI JHJ HUANG W HOWORTH P SONI R FULLER M SAUER H NOWOTNIK AC SUZDAK PD
Citation: Jp. Steiner et al., NEUROTROPHIC IMMUNOPHILIN LIGANDS STIMULATE STRUCTURAL AND FUNCTIONALRECOVERY IN NEURODEGENERATIVE ANIMAL-MODELS, Proceedings of the National Academy of Sciences of the United Statesof America, 94(5), 1997, pp. 2019-2024
ANTICONVULSANT EFFECTS OF MUSCARINICS
Authors: SWEDBERG MDB SHANNON HE SHEARDOWN MJ KLITGAARD H BYMASTER FP WARD JS MITCH CH OLESEN PH ESKESEN K SUZDAK PD CALLIGARO DO SAUERBERG P
Citation: Mdb. Swedberg et al., ANTICONVULSANT EFFECTS OF MUSCARINICS, Life sciences, 60(13-14), 1997, pp. 80-80
M-1 RECEPTOR AGONIST ACTIVITY IS NOT A REQUIREMENT FOR MUSCARINIC ANTINOCICEPTION
Authors: SHEARDOWN MJ SHANNON HE SWEDBERG MDB SUZDAK PD BYMASTER FP OLESEN PH MITCH CH WARD JS SAUERBERG P
Citation: Mj. Sheardown et al., M-1 RECEPTOR AGONIST ACTIVITY IS NOT A REQUIREMENT FOR MUSCARINIC ANTINOCICEPTION, The Journal of pharmacology and experimental therapeutics, 281(2), 1997, pp. 868-875
BUTYLTHIO[2.2.2] (NNC 11-1053 LY297802) - AN ORALLY-ACTIVE MUSCARINICAGONIST ANALGESIC/
Authors: SWEDBERG MDB SHEARDOWN MJ SAUERBERG P OLESEN PH SUZDAK PD HANSEN KT BYMASTER FP WARD JS MITCH CH CALLIGARO DO DELAPP NW SHANNON HE
Citation: Mdb. Swedberg et al., BUTYLTHIO[2.2.2] (NNC 11-1053 LY297802) - AN ORALLY-ACTIVE MUSCARINICAGONIST ANALGESIC/, The Journal of pharmacology and experimental therapeutics, 281(2), 1997, pp. 876-883
PHARMACOLOGY OF BUTYLTHIO[2.2.2] (LY297802 NNC11-1053) - A NOVEL ANALGESIC WITH MIXED MUSCARINIC RECEPTOR AGONIST AND ANTAGONIST ACTIVITY/
Authors: SHANNON HE SHEARDOWN MJ BYMASTER FP CALLIGARO DO DELAPP NW GIDDA J MITCH CH SAWYER BD STENGEL PW WARD JS WONG DT OLESEN PH SUZDAK PD SAUERBERG P SWEDBERG MDB
Citation: He. Shannon et al., PHARMACOLOGY OF BUTYLTHIO[2.2.2] (LY297802 NNC11-1053) - A NOVEL ANALGESIC WITH MIXED MUSCARINIC RECEPTOR AGONIST AND ANTAGONIST ACTIVITY/, The Journal of pharmacology and experimental therapeutics, 281(2), 1997, pp. 884-894
PET STUDY OF THE M(1)-AGONISTS [C-11] XANOMELINE AND [C-11] BUTYLTHIO-TZTP IN MONKEY AND MAN
Authors: FARDE L SUHARA T HALLDIN C NYBACK H NAKASHIMA Y SWAHN CG KARLSSON P GINOVART N BYMASTER FP SHANNON HE FOGED C SUZDAK PD SAUERBERG P
Citation: L. Farde et al., PET STUDY OF THE M(1)-AGONISTS [C-11] XANOMELINE AND [C-11] BUTYLTHIO-TZTP IN MONKEY AND MAN, Dementia, 7(4), 1996, pp. 187-195
3-(3-ALKYLTHIO-1,2,5-THIADIAZOL-4-YL)1-AZABICYCLE - STRUCTURE-ACTIVITY-RELATIONSHIPS FOR ANTINOCICEPTION MEDIATED BY CENTRAL MUSCARINIC RECEPTORS
Authors: OLESEN PH SAUERBERG P TREPPENDAHL S LARSSON O SHEARDOWN MJ SUZDAK PD MITCH CH WARD JS BYMASTER FP SHANNON HE SWEDBERG MDB
Citation: Ph. Olesen et al., 3-(3-ALKYLTHIO-1,2,5-THIADIAZOL-4-YL)1-AZABICYCLE - STRUCTURE-ACTIVITY-RELATIONSHIPS FOR ANTINOCICEPTION MEDIATED BY CENTRAL MUSCARINIC RECEPTORS, European journal of medicinal chemistry, 31(3), 1996, pp. 221-230
ANTICONVULSANT PROFILE OF THE IMIDAZOQUINAZOLINES NNC 14-0185 AND NNC14-0189 IN RATS AND MICE
Authors: JACKSON HC HANSEN HC KRISTIANSEN M SUZDAK PD KLITGAARD H JUDGE ME SWEDBERG MDB
Citation: Hc. Jackson et al., ANTICONVULSANT PROFILE OF THE IMIDAZOQUINAZOLINES NNC 14-0185 AND NNC14-0189 IN RATS AND MICE, European journal of pharmacology, 308(1), 1996, pp. 21-30
SYNTHESIS AND BINDING-PROPERTIES OF [H-3]NNC-12-0781, A NEW RADIOLIGAND FOR THE DOPAMINE REUPTAKE SYSTEM
Authors: MULLER L HALL H HALLDIN C FARDE L HOHLWEG R SUZDAK PD NIELSEN EB FOGED C
Citation: L. Muller et al., SYNTHESIS AND BINDING-PROPERTIES OF [H-3]NNC-12-0781, A NEW RADIOLIGAND FOR THE DOPAMINE REUPTAKE SYSTEM, Nuclear medicine and biology, 22(6), 1995, pp. 711-717
CHARACTERIZATION OF NOVEL LIGANDS FOR WILD-TYPE AND NATURAL MUTANT DIAZEPAM-INSENSITIVE BENZODIAZEPINE RECEPTORS
Authors: WONG G UUSIOUKARI M HANSEN HC SUZDAK PD KORPI ER
Citation: G. Wong et al., CHARACTERIZATION OF NOVEL LIGANDS FOR WILD-TYPE AND NATURAL MUTANT DIAZEPAM-INSENSITIVE BENZODIAZEPINE RECEPTORS, European journal of pharmacology. Molecular pharmacology section, 289(2), 1995, pp. 335-342
EFFECTS OF CHRONIC TIAGABINE TREATMENT ON [H-3] GABA(A), [H-3] GABA(B) AND [H-3] TIAGABINE BINDING TO SECTIONS FROM MICE BRAIN
Authors: THOMSEN C SUZDAK PD
Citation: C. Thomsen et Pd. Suzdak, EFFECTS OF CHRONIC TIAGABINE TREATMENT ON [H-3] GABA(A), [H-3] GABA(B) AND [H-3] TIAGABINE BINDING TO SECTIONS FROM MICE BRAIN, Epilepsy research, 21(2), 1995, pp. 79-88
MUSCARINIC AGONISTS AS ANALGESICS - ANTINOCICEPTIVE ACTIVITY VERSUS M(1) ACTIVITY - SAR OF ALKYLTHIO-TZTPS AND RELATED 1,2,5-THIADIAZOLE ANALOGS
Authors: SAUERBERG P OLESEN PH SHEARDOWN MJ SUZDAK PD SHANNON HE BYMASTER FP CALLIGARO DO MITCH CH WARD JS SWEDBERG MDB
Citation: P. Sauerberg et al., MUSCARINIC AGONISTS AS ANALGESICS - ANTINOCICEPTIVE ACTIVITY VERSUS M(1) ACTIVITY - SAR OF ALKYLTHIO-TZTPS AND RELATED 1,2,5-THIADIAZOLE ANALOGS, Life sciences, 56(11-12), 1995, pp. 807-814
3-(3-HEXYLOXYPYRAZINYL) QUINUCLIDINE AS A FUNCTIONALLY SELECTIVE M(1)AGONIST
Authors: WARD JS MERRITT L CALLIGARO DO BYMASTER FP SHANNON HE SAWYER BD MITCH CH SHEARDOWN MJ OLESEN PH SUZDAK PD SWEDBERG MDB
Citation: Js. Ward et al., 3-(3-HEXYLOXYPYRAZINYL) QUINUCLIDINE AS A FUNCTIONALLY SELECTIVE M(1)AGONIST, Life sciences, 56(11-12), 1995, pp. 1003-1003
SIDE-CHAIN STERIC BULK AND MUSCARINIC AGONIST SAR IN ALKOXY-TZTPS
Authors: MITCH CH BYMASTER FP CALLIGARO DO QUIMBY SJ SAWYER BD WARD JS OLESEN PH SAUERBERG P SHEARDOWN MJ SUZDAK PD SWEDBERG M SHANNON HE
Citation: Ch. Mitch et al., SIDE-CHAIN STERIC BULK AND MUSCARINIC AGONIST SAR IN ALKOXY-TZTPS, Life sciences, 56(11-12), 1995, pp. 1004-1004
IN-VITRO PHARMACOLOGY OF THE MUSCARINIC ANALGESIC LY297802 NNC111053/
Authors: SHANNON HE BYMASTER FP CALLIGARO DO MITCH CH SAWYER BD WARD JS SHEARDOWN MJ OLESEN PH SAUERBERG P SUZDAK PD SWEDBERG MDB
Citation: He. Shannon et al., IN-VITRO PHARMACOLOGY OF THE MUSCARINIC ANALGESIC LY297802 NNC111053/, Life sciences, 56(11-12), 1995, pp. 1046-1046
NNC-11-1053 LY-297802 - AN ANTINOCICEPTIVE ORALLY ACTING MUSCARINIC AGONIST IN MOUSE AND RAT
Authors: SWEDBERG MDB SHEARDOWN MJ SAUERBERG P OLESEN P SUZDAK PD BYMASTER FP WARD JS MITCH CH CALLIGARO DO SHANNON HE
Citation: Mdb. Swedberg et al., NNC-11-1053 LY-297802 - AN ANTINOCICEPTIVE ORALLY ACTING MUSCARINIC AGONIST IN MOUSE AND RAT, Life sciences, 56(11-12), 1995, pp. 1047-1047
THE EFFECT OF LORAZEPAM TOLERANCE AND WITHDRAWAL ON METABOTROPIC GLUTAMATE-RECEPTOR FUNCTION
Authors: MORTENSEN M SUZDAK PD THOMSEN C
Citation: M. Mortensen et al., THE EFFECT OF LORAZEPAM TOLERANCE AND WITHDRAWAL ON METABOTROPIC GLUTAMATE-RECEPTOR FUNCTION, The Journal of pharmacology and experimental therapeutics, 274(1), 1995, pp. 155-163
A REVIEW OF THE PRECLINICAL PHARMACOLOGY OF TIAGABINE - A POTENT AND SELECTIVE ANTICONVULSANT GABA UPTAKE INHIBITOR
Authors: SUZDAK PD JANSEN JA
Citation: Pd. Suzdak et Ja. Jansen, A REVIEW OF THE PRECLINICAL PHARMACOLOGY OF TIAGABINE - A POTENT AND SELECTIVE ANTICONVULSANT GABA UPTAKE INHIBITOR, Epilepsia, 36(6), 1995, pp. 612-626
ANTICONVULSANT EFFECTS OF THE IMIDAZOQUINAZOLINES, NCC-14-0185 AND NNC-14-0189 - COMPARISON WITH DIAZEPAM
Authors: JACKSON HC HANSEN HC KRISTIANSEN M SUZDAK PD JUDGE ME SWEDBERG MDB
Citation: Hc. Jackson et al., ANTICONVULSANT EFFECTS OF THE IMIDAZOQUINAZOLINES, NCC-14-0185 AND NNC-14-0189 - COMPARISON WITH DIAZEPAM, British Journal of Pharmacology, 114, 1995, pp. 288-288
PYRAZOLO[1,5-A]PYRIDINES AND PYRAZOLO[1,5-B]PYRIDAZINES AS 5HT(3)-ANTAGONISTS
Authors: HANSEN JB WEIS J SUZDAK PD ESKESEN K
Citation: Jb. Hansen et al., PYRAZOLO[1,5-A]PYRIDINES AND PYRAZOLO[1,5-B]PYRIDAZINES AS 5HT(3)-ANTAGONISTS, Bioorganic & medicinal chemistry letters, 4(5), 1994, pp. 695-698
SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF ALKYL SUBSTITUTED ANALOGS OF THE FUNCTIONAL M(1) SELECTIVE MUSCARINIC RECEPTOR AGONIST XANOMELINE
Authors: QUIMBY SJ SHANNON HE BYMASTER FP SAUERBERG P OLESEN PH SHEARDOWN MJ SUZDAK PD MITCH CH
Citation: Sj. Quimby et al., SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF ALKYL SUBSTITUTED ANALOGS OF THE FUNCTIONAL M(1) SELECTIVE MUSCARINIC RECEPTOR AGONIST XANOMELINE, Bioorganic & medicinal chemistry letters, 4(18), 1994, pp. 2205-2210
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