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Results: 1-13 |
Results: 13
CELLULAR BUT NOT PLASMA PHARMACOKINETICS OF LOMETREXOL CORRELATE WITHTHE OCCURRENCE OF CUMULATIVE HEMATOLOGICAL TOXICITY
Authors: SYNOLD TW NEWMAN EM CARROLL M MUGGIA FM GROSHEN S JOHNSON K DOROSHOW JH
Citation: Tw. Synold et al., CELLULAR BUT NOT PLASMA PHARMACOKINETICS OF LOMETREXOL CORRELATE WITHTHE OCCURRENCE OF CUMULATIVE HEMATOLOGICAL TOXICITY, Clinical cancer research, 4(10), 1998, pp. 2349-2355
ANTINEOPLASTIC ACTIVITY OF CONTINUOUS EXPOSURE TO DEXRAZOXANE - POTENTIAL NEW ROLE AS A NOVEL TOPOISOMERASE-II INHIBITOR
Authors: SYNOLD TW TETEF ML DOROSHOW JH
Citation: Tw. Synold et al., ANTINEOPLASTIC ACTIVITY OF CONTINUOUS EXPOSURE TO DEXRAZOXANE - POTENTIAL NEW ROLE AS A NOVEL TOPOISOMERASE-II INHIBITOR, Seminars in oncology, 25(4), 1998, pp. 93-99
VALIDATION OF A LIMITED SAMPLING MODEL TO DETERMINE ETOPOSIDE AREA-UNDER-THE-CURVE
Authors: LUM BL LANE KJ SYNOLD TW GORAM A CHARNICK SB SIKIC BI
Citation: Bl. Lum et al., VALIDATION OF A LIMITED SAMPLING MODEL TO DETERMINE ETOPOSIDE AREA-UNDER-THE-CURVE, Pharmacotherapy, 17(5), 1997, pp. 887-890
DIFFERENCES IN FOLYLPOLYGLUTAMATE SYNTHETASE AND DIHYDROFOLATE-REDUCTASE EXPRESSION IN HUMAN B-LINEAGE VERSUS T-LINEAGE LEUKEMIC LYMPHOBLASTS - MECHANISMS FOR LINEAGE DIFFERENCES IN METHOTREXATE POLYGLUTAMYLATION AND CYTOTOXICITY
Authors: GALPIN AJ SCHUETZ JD MASSON E YANISHEVSKI Y SYNOLD TW BARREDO JC PUI CH RELLING MV EVANS WE
Citation: Aj. Galpin et al., DIFFERENCES IN FOLYLPOLYGLUTAMATE SYNTHETASE AND DIHYDROFOLATE-REDUCTASE EXPRESSION IN HUMAN B-LINEAGE VERSUS T-LINEAGE LEUKEMIC LYMPHOBLASTS - MECHANISMS FOR LINEAGE DIFFERENCES IN METHOTREXATE POLYGLUTAMYLATION AND CYTOTOXICITY, Molecular pharmacology, 52(1), 1997, pp. 155-163
FAILURE OF PRETREATMENT WITH INTRAVENOUS FOLIC-ACID TO ALTER THE CUMULATIVE HEMATOLOGIC TOXICITY OF LOMETREXOL
Authors: MUGGIA FM SYNOLD TW NEWMAN EM JEFFERS S LEICHMAN LP DOROSHOW JH JOHNSON K GROSHEN S
Citation: Fm. Muggia et al., FAILURE OF PRETREATMENT WITH INTRAVENOUS FOLIC-ACID TO ALTER THE CUMULATIVE HEMATOLOGIC TOXICITY OF LOMETREXOL, Journal of the National Cancer Institute, 88(20), 1996, pp. 1495-1496
SIMPLE AND SENSITIVE METHOD FOR THE QUANTITATIVE-ANALYSIS OF LOMETREXOL IN PLASMA USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION
Authors: SYNOLD TW XI BX NEWMAN EM MUGGIA FM DOROSHOW JH
Citation: Tw. Synold et al., SIMPLE AND SENSITIVE METHOD FOR THE QUANTITATIVE-ANALYSIS OF LOMETREXOL IN PLASMA USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION, Journal of chromatography B. Biomedical applications, 683(2), 1996, pp. 245-249
ROLE OF FOLYLPOLYGUTAMATE SYNTHETASE (FPGS) IN ANTIFOLATE CHEMOTHERAPY - A BIOCHEMICAL AND CLINICAL UPDATE
Authors: SYNOLD TW WILLITS EM BARREDO JC
Citation: Tw. Synold et al., ROLE OF FOLYLPOLYGUTAMATE SYNTHETASE (FPGS) IN ANTIFOLATE CHEMOTHERAPY - A BIOCHEMICAL AND CLINICAL UPDATE, Leukemia & lymphoma, 21(1-2), 1996, pp. 9-15
ALLOPURINOL INHIBITS DE-NOVO PURINE SYNTHESIS IN LYMPHOBLASTS OF CHILDREN WITH ACUTE LYMPHOBLASTIC-LEUKEMIA
Authors: MASSON E SYNOLD TW RELLING MV SCHUETZ JD SANDLUND JT PUI CH EVANS WE
Citation: E. Masson et al., ALLOPURINOL INHIBITS DE-NOVO PURINE SYNTHESIS IN LYMPHOBLASTS OF CHILDREN WITH ACUTE LYMPHOBLASTIC-LEUKEMIA, Leukemia, 10(1), 1996, pp. 56-60
ACCUMULATION OF METHOTREXATE POLYGLUTAMATES IN LYMPHOBLASTS IS A DETERMINANT OF ANTILEUKEMIC EFFECTS IN-VIVO - A RATIONALE FOR HIGH-DOSE METHOTREXATE
Authors: MASSON E RELLING MV SYNOLD TW LIU Q SCHUETZ JD SANDLUND JT PUI CH EVANS WE
Citation: E. Masson et al., ACCUMULATION OF METHOTREXATE POLYGLUTAMATES IN LYMPHOBLASTS IS A DETERMINANT OF ANTILEUKEMIC EFFECTS IN-VIVO - A RATIONALE FOR HIGH-DOSE METHOTREXATE, The Journal of clinical investigation, 97(1), 1996, pp. 73-80
NEURAL-NETWORK (NN) AND LINEAR-REGRESSION LIMITED SAMPLING MODELS (LSM) FOR ETOPOSIDE (E) AUC DETERMINATIONS
Authors: LUM BL SYNOLD TW LANE K CHARNICK SB SIKIC BI
Citation: Bl. Lum et al., NEURAL-NETWORK (NN) AND LINEAR-REGRESSION LIMITED SAMPLING MODELS (LSM) FOR ETOPOSIDE (E) AUC DETERMINATIONS, Clinical pharmacology and therapeutics, 59(2), 1996, pp. 2-2
RENAL-FUNCTION AND METHOTREXATE CLEARANCE IN CHILDREN WITH NEWLY-DIAGNOSED LEUKEMIA
Authors: MURRY DJ SYNOLD TW PUI CH RODMAN JH
Citation: Dj. Murry et al., RENAL-FUNCTION AND METHOTREXATE CLEARANCE IN CHILDREN WITH NEWLY-DIAGNOSED LEUKEMIA, Pharmacotherapy, 15(2), 1995, pp. 144-149
BLAST CELL METHOTREXATE-POLYGLUTAMATE ACCUMULATION IN-VIVO DIFFERS BYLINEAGE, PLOIDY, AND METHOTREXATE DOSE IN ACUTE LYMPHOBLASTIC-LEUKEMIA
Authors: SYNOLD TW RELLING MV BOYETT JM RIVERA GK SANDLUND JT MAHMOUD H CRIST WM PUI CH EVANS WE
Citation: Tw. Synold et al., BLAST CELL METHOTREXATE-POLYGLUTAMATE ACCUMULATION IN-VIVO DIFFERS BYLINEAGE, PLOIDY, AND METHOTREXATE DOSE IN ACUTE LYMPHOBLASTIC-LEUKEMIA, The Journal of clinical investigation, 94(5), 1994, pp. 1996-2001
DIFFERENCES IN CONSTITUTIVE AND POST-METHOTREXATE FOLYLPOLYGLUTAMATE SYNTHETASE-ACTIVITY IN B-LINEAGE AND T-LINEAGE LEUKEMIA
Authors: BARREDO JC SYNOLD TW LAVER J RELLING MV PUI CH PRIEST DG EVANS WE
Citation: Jc. Barredo et al., DIFFERENCES IN CONSTITUTIVE AND POST-METHOTREXATE FOLYLPOLYGLUTAMATE SYNTHETASE-ACTIVITY IN B-LINEAGE AND T-LINEAGE LEUKEMIA, Blood, 84(2), 1994, pp. 564-569
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