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Results: 1-19 |
Results: 19
PROBING THE ACTIVE-SITE OF CYTOCHROME-P450 2B1 - METABOLISM OF 7-ALKOXYCOUMARINS BY THE WILD-TYPE AND 5 SITE-DIRECTED MUTANTS
Authors: KOBAYASHI Y FANG XJ SZKLARZ GD HALPERT JR
Citation: Y. Kobayashi et al., PROBING THE ACTIVE-SITE OF CYTOCHROME-P450 2B1 - METABOLISM OF 7-ALKOXYCOUMARINS BY THE WILD-TYPE AND 5 SITE-DIRECTED MUTANTS, Biochemistry, 37(19), 1998, pp. 6679-6688
STRUCTURAL DETERMINANTS OF PROGESTERONE HYDROXYLATION BY CYTOCHROME-P450 2B5 - THE ROLE OF NONSUBSTRATE RECOGNITION SITE RESIDUES
Authors: HE YQ HARLOW GR SZKLARZ GD HALPERT JR
Citation: Yq. He et al., STRUCTURAL DETERMINANTS OF PROGESTERONE HYDROXYLATION BY CYTOCHROME-P450 2B5 - THE ROLE OF NONSUBSTRATE RECOGNITION SITE RESIDUES, Archives of biochemistry and biophysics, 350(2), 1998, pp. 333-339
MOLECULAR MODELING OF CYTOCHROME-P450 3A4
Authors: SZKLARZ GD HALPERT JR
Citation: Gd. Szklarz et Jr. Halpert, MOLECULAR MODELING OF CYTOCHROME-P450 3A4, Journal of computer-aided molecular design, 11(3), 1997, pp. 265-272
MOLECULAR-BASIS OF P450 2B AND 3A SPECIFICITY - MUTANTS, MODELS, AND MECHANISMS
Authors: HALPERT JR DOMANSKI T FANG X HARLOW GR HE YA HE YO KOBAYASHI Y STROBEL SM SZKLARZ GD
Citation: Jr. Halpert et al., MOLECULAR-BASIS OF P450 2B AND 3A SPECIFICITY - MUTANTS, MODELS, AND MECHANISMS, The FASEB journal, 11(9), 1997, pp. 14-14
MOLECULAR MODELING OF CYTOCHROMES P450 2B AND 3A
Authors: SZKLARZ GD
Citation: Gd. Szklarz, MOLECULAR MODELING OF CYTOCHROMES P450 2B AND 3A, The FASEB journal, 11(9), 1997, pp. 48-48
IDENTIFICATION OF KEY RESIDUES IN HUMAN CYTOCHROME-P450 3A4 BY CASSETTE, SITE-DIRECTED AND RANDOM MUTAGENESIS
Authors: HE YA HE YQ SZKLARZ GD HALPERT JR
Citation: Ya. He et al., IDENTIFICATION OF KEY RESIDUES IN HUMAN CYTOCHROME-P450 3A4 BY CASSETTE, SITE-DIRECTED AND RANDOM MUTAGENESIS, The FASEB journal, 11(9), 1997, pp. 145-145
SIGNIFICANCE OF GLYCINE-478 IN CYTOCHROME-P450 2B1 ON THE METABOLISM OF N-BENZYL-1-AMINOBENZOTRIAZOLE
Authors: KENT UM HANNA IH SZKLARZ GD VAZ ADN HALPERT JR BEND JR HOLLENBERG PF
Citation: Um. Kent et al., SIGNIFICANCE OF GLYCINE-478 IN CYTOCHROME-P450 2B1 ON THE METABOLISM OF N-BENZYL-1-AMINOBENZOTRIAZOLE, The FASEB journal, 11(9), 1997, pp. 187-187
USE OF HOMOLOGY MODELING IN CONJUNCTION WITH SITE-DIRECTED MUTAGENESIS FOR ANALYSIS OF STRUCTURE-FUNCTION-RELATIONSHIPS OF MAMMALIAN CYTOCHROMES P450
Authors: SZKLARZ GD HALPERT JR
Citation: Gd. Szklarz et Jr. Halpert, USE OF HOMOLOGY MODELING IN CONJUNCTION WITH SITE-DIRECTED MUTAGENESIS FOR ANALYSIS OF STRUCTURE-FUNCTION-RELATIONSHIPS OF MAMMALIAN CYTOCHROMES P450, Life sciences, 61(26), 1997, pp. 2507-2520
SIGNIFICANCE OF GLYCINE-478 IN THE METABOLISM OF N-BENZYL-1-AMINOBENZOTRIAZOLE TO REACTIVE INTERMEDIATES BY CYTOCHROME-P450 2B1
Authors: KENT UM HANNA IH SZKLARZ GD VAZ ADN HALPERT JR BEND JR HOLLENBERG PF
Citation: Um. Kent et al., SIGNIFICANCE OF GLYCINE-478 IN THE METABOLISM OF N-BENZYL-1-AMINOBENZOTRIAZOLE TO REACTIVE INTERMEDIATES BY CYTOCHROME-P450 2B1, Biochemistry, 36(39), 1997, pp. 11707-11716
IDENTIFICATION OF 3 KEY RESIDUES IN SUBSTRATE RECOGNITION SITE-5 OF HUMAN CYTOCHROME-P450 3A4 BY CASSETTE AND SITE-DIRECTED MUTAGENESIS
Authors: HE YA HE YQ SZKLARZ GD HALPERT JR
Citation: Ya. He et al., IDENTIFICATION OF 3 KEY RESIDUES IN SUBSTRATE RECOGNITION SITE-5 OF HUMAN CYTOCHROME-P450 3A4 BY CASSETTE AND SITE-DIRECTED MUTAGENESIS, Biochemistry, 36(29), 1997, pp. 8831-8839
SECOBARBITAL-MEDIATED INACTIVATION OF CYTOCHROME-P450 2B1 AND ITS ACTIVE-SITE MUTANTS - PARTITIONING BETWEEN HEME AND PROTEIN ALKYLATION AND EPOXIDATION
Authors: HE K HE YA SZKLARZ GD HALPERT JR CORREIA MA
Citation: K. He et al., SECOBARBITAL-MEDIATED INACTIVATION OF CYTOCHROME-P450 2B1 AND ITS ACTIVE-SITE MUTANTS - PARTITIONING BETWEEN HEME AND PROTEIN ALKYLATION AND EPOXIDATION, The Journal of biological chemistry, 271(42), 1996, pp. 25864-25872
INTERCONVERSION OF THE ANDROSTENEDIONE HYDROXYLASE SPECIFICITIES OF CYTOCHROMES P450 2B4 AND 2B5 UPON SIMULTANEOUS SITE-DIRECTED MUTAGENESIS OF 4 KEY SUBSTRATE RECOGNITION RESIDUES
Authors: HE YQ SZKLARZ GD HALPERT JR
Citation: Yq. He et al., INTERCONVERSION OF THE ANDROSTENEDIONE HYDROXYLASE SPECIFICITIES OF CYTOCHROMES P450 2B4 AND 2B5 UPON SIMULTANEOUS SITE-DIRECTED MUTAGENESIS OF 4 KEY SUBSTRATE RECOGNITION RESIDUES, Archives of biochemistry and biophysics, 335(1), 1996, pp. 152-160
ELUCIDATION OF AMINO-ACID-RESIDUES CRITICAL FOR UNIQUE ACTIVITIES OF RABBIT CYTOCHROME-P450 2B5 USING HYBRID ENZYMES AND RECIPROCAL SITE-DIRECTED MUTAGENESIS WITH RABBIT CYTOCHROME-P450 2B4
Authors: SZKLARZ GD HE YQ KEDZIE KM HALPERT JR BURNETT VL
Citation: Gd. Szklarz et al., ELUCIDATION OF AMINO-ACID-RESIDUES CRITICAL FOR UNIQUE ACTIVITIES OF RABBIT CYTOCHROME-P450 2B5 USING HYBRID ENZYMES AND RECIPROCAL SITE-DIRECTED MUTAGENESIS WITH RABBIT CYTOCHROME-P450 2B4, Archives of biochemistry and biophysics, 327(2), 1996, pp. 308-318
SITE-DIRECTED MUTAGENESIS AS A TOOL FOR MOLECULAR MODELING OF CYTOCHROME-P450 2B1
Authors: SZKLARZ GD HE YA HALPERT JR
Citation: Gd. Szklarz et al., SITE-DIRECTED MUTAGENESIS AS A TOOL FOR MOLECULAR MODELING OF CYTOCHROME-P450 2B1, Biochemistry, 34(44), 1995, pp. 14312-14322
MOLECULAR MODELING OF CYTOCHROME-P450-2B1 AS A TOOL FOR UNDERSTANDINGSTRUCTURE-FUNCTION-RELATIONSHIPS
Authors: SZKLARZ GD ORNSTEIN RL HALPERT JR
Citation: Gd. Szklarz et al., MOLECULAR MODELING OF CYTOCHROME-P450-2B1 AS A TOOL FOR UNDERSTANDINGSTRUCTURE-FUNCTION-RELATIONSHIPS, The FASEB journal, 8(4), 1994, pp. 10000100-10000100
APPLICATION OF 3-DIMENSIONAL HOMOLOGY MODELING OF CYTOCHROME-P450 2B1FOR INTERPRETATION OF SITE-DIRECTED MUTAGENESIS RESULTS
Authors: SZKLARZ GD ORNSTEIN RL HALPERT JR
Citation: Gd. Szklarz et al., APPLICATION OF 3-DIMENSIONAL HOMOLOGY MODELING OF CYTOCHROME-P450 2B1FOR INTERPRETATION OF SITE-DIRECTED MUTAGENESIS RESULTS, Journal of biomolecular structure & dynamics, 12(1), 1994, pp. 61-78
THE MITOCHONDRIAL ENVIRONMENT IS REQUIRED FOR ACTIVITY OF THE CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME, CYTOCHROME P450SCC
Authors: BLACK SM HARIKRISHNA JA SZKLARZ GD MILLER WL
Citation: Sm. Black et al., THE MITOCHONDRIAL ENVIRONMENT IS REQUIRED FOR ACTIVITY OF THE CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME, CYTOCHROME P450SCC, Proceedings of the National Academy of Sciences of the United Statesof America, 91(15), 1994, pp. 7247-7251
SITE-DIRECTED MUTAGENESIS OF PUTATIVE SUBSTRATE RECOGNITION SITES IN CYTOCHROME-P450-2B11 - IMPORTANCE OF AMINO-ACID RESIDUE-114, RESIDUE-290, AND RESIDUE-363 FOR SUBSTRATE-SPECIFICITY
Authors: HASLER JA HARLOW GR SZKLARZ GD JOHN GH KEDZIE KM BURNETT VL HE YA KAMINSKY LS HALPERT JR
Citation: Ja. Hasler et al., SITE-DIRECTED MUTAGENESIS OF PUTATIVE SUBSTRATE RECOGNITION SITES IN CYTOCHROME-P450-2B11 - IMPORTANCE OF AMINO-ACID RESIDUE-114, RESIDUE-290, AND RESIDUE-363 FOR SUBSTRATE-SPECIFICITY, Molecular pharmacology, 46(2), 1994, pp. 338-345
CONSTRUCTION AND FUNCTION OF FUSION ENZYMES OF THE HUMAN CYTOCHROME-P450SCC SYSTEM
Authors: HARIKRISHNA JA BLACK SM SZKLARZ GD MILLER WL
Citation: Ja. Harikrishna et al., CONSTRUCTION AND FUNCTION OF FUSION ENZYMES OF THE HUMAN CYTOCHROME-P450SCC SYSTEM, DNA and cell biology, 12(5), 1993, pp. 371-379
Risultati: 1-19 |