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Results: 1-16 |
Results: 16
A RATIONAL DESIGN STRATEGY FOR PROTEIN HORMONE SUPERAGONISTS
Authors: GROSSMANN M LEITOLF H WEINTRAUB BD SZKUDLINSKI MW
Citation: M. Grossmann et al., A RATIONAL DESIGN STRATEGY FOR PROTEIN HORMONE SUPERAGONISTS, Nature biotechnology, 16(9), 1998, pp. 871-875
NOVEL INSIGHTS INTO THE MOLECULAR MECHANISMS OF HUMAN THYROTROPIN ACTION - STRUCTURAL, PHYSIOLOGICAL, AND THERAPEUTIC IMPLICATIONS FOR THE GLYCOPROTEIN HORMONE FAMILY
Authors: GROSSMANN M WEINTRAUB BD SZKUDLINSKI MW
Citation: M. Grossmann et al., NOVEL INSIGHTS INTO THE MOLECULAR MECHANISMS OF HUMAN THYROTROPIN ACTION - STRUCTURAL, PHYSIOLOGICAL, AND THERAPEUTIC IMPLICATIONS FOR THE GLYCOPROTEIN HORMONE FAMILY, Endocrine reviews, 18(4), 1997, pp. 476-501
HUMAN THYROID-STIMULATING HORMONE (HTSH) SUBUNIT GENE FUSION PRODUCESHTSH WITH INCREASED STABILITY AND SERUM HALF-LIFE AND COMPENSATES FORMUTAGENESIS-INDUCED DEFECTS IN SUBUNIT ASSOCIATION
Authors: GROSSMANN M WONG R SZKUDLINSKI MW WEINTRAUAB BD
Citation: M. Grossmann et al., HUMAN THYROID-STIMULATING HORMONE (HTSH) SUBUNIT GENE FUSION PRODUCESHTSH WITH INCREASED STABILITY AND SERUM HALF-LIFE AND COMPENSATES FORMUTAGENESIS-INDUCED DEFECTS IN SUBUNIT ASSOCIATION, The Journal of biological chemistry, 272(34), 1997, pp. 21312-21316
SUBSTITUTION OF THE SEAT-BELT REGION OF THE THYROID-STIMULATING HORMONE (TSH) BETA-SUBUNIT WITH THE CORRESPONDING REGIONS OF CHORIOGONADOTROPIN OR FOLLITROPIN CONFERS LUTEOTROPIC BUT NOT FOLLITROPIC ACTIVITY TO CHIMERIC TSH
Authors: GROSSMANN M SZKUDLINSKI MW WONG R DIAS JA JI TH WEINTRAUB BD
Citation: M. Grossmann et al., SUBSTITUTION OF THE SEAT-BELT REGION OF THE THYROID-STIMULATING HORMONE (TSH) BETA-SUBUNIT WITH THE CORRESPONDING REGIONS OF CHORIOGONADOTROPIN OR FOLLITROPIN CONFERS LUTEOTROPIC BUT NOT FOLLITROPIC ACTIVITY TO CHIMERIC TSH, The Journal of biological chemistry, 272(24), 1997, pp. 15532-15540
EXPRESSION OF BIOLOGICALLY-ACTIVE HUMAN THYROTROPIN (HTSH) IN A BACULOVIRUS SYSTEM - EFFECT OF INSECT-CELL GLYCOSYLATION ON HTSH ACTIVITY IN-VITRO AND IN-VIVO
Authors: GROSSMANN M WONG R TEH NG TROPEA JE EASTPALMER J WEINTRAUB BD SZKUDLINSKI MW
Citation: M. Grossmann et al., EXPRESSION OF BIOLOGICALLY-ACTIVE HUMAN THYROTROPIN (HTSH) IN A BACULOVIRUS SYSTEM - EFFECT OF INSECT-CELL GLYCOSYLATION ON HTSH ACTIVITY IN-VITRO AND IN-VIVO, Endocrinology, 138(1), 1997, pp. 92-100
ENGINEERING HUMAN GLYCOPROTEIN HORMONE SUPERACTIVE ANALOGS
Authors: SZKUDLINSKI MW TEH NG GROSSMANN M TROPEA JE WEINTRAUB BD
Citation: Mw. Szkudlinski et al., ENGINEERING HUMAN GLYCOPROTEIN HORMONE SUPERACTIVE ANALOGS, Nature biotechnology, 14(10), 1996, pp. 1257-1263
STRUCTURE-FUNCTION STUDIES OF HUMAN TSH - NEW ADVANCES IN DESIGN OF GLYCOPROTEIN HORMONE ANALOGS
Authors: SZKUDLINSKI MW GROSSMANN M WEINTRAUB BD
Citation: Mw. Szkudlinski et al., STRUCTURE-FUNCTION STUDIES OF HUMAN TSH - NEW ADVANCES IN DESIGN OF GLYCOPROTEIN HORMONE ANALOGS, Trends in endocrinology and metabolism, 7(8), 1996, pp. 277-286
A NOVEL, NONRADIOACTIVE IN-VIVO BIOASSAY OF THYROTROPIN (TSH)
Authors: EASTPALMER J SZKUDLINSKI MW LEE J THOTAKURA NR WEINTRAUB BD
Citation: J. Eastpalmer et al., A NOVEL, NONRADIOACTIVE IN-VIVO BIOASSAY OF THYROTROPIN (TSH), Thyroid, 5(1), 1995, pp. 55-59
ROLE OF THE CARBOXY-TERMINAL RESIDUES OF THE ALPHA-SUBUNIT IN THE EXPRESSION AND BIOACTIVITY OF HUMAN THYROID-STIMULATING HORMONE
Authors: GROSSMANN M SZKUDLINSKI MW ZENG HW ZAKI K JI IH TROPEA JE JI TH WEINTRAUB BD
Citation: M. Grossmann et al., ROLE OF THE CARBOXY-TERMINAL RESIDUES OF THE ALPHA-SUBUNIT IN THE EXPRESSION AND BIOACTIVITY OF HUMAN THYROID-STIMULATING HORMONE, Molecular endocrinology, 9(8), 1995, pp. 948-958
SUBUNIT-SPECIFIC FUNCTIONS OF N-LINKED OLIGOSACCHARIDES IN HUMAN THYROTROPIN - ROLE OF TERMINAL RESIDUES OF ALPHA-SUBUNIT AND BETA-SUBUNIT OLIGOSACCHARIDES IN METABOLIC-CLEARANCE AND BIOACTIVITY
Authors: SZKUDLINSKI MW THOTAKURA NR WEINTRAUB BD
Citation: Mw. Szkudlinski et al., SUBUNIT-SPECIFIC FUNCTIONS OF N-LINKED OLIGOSACCHARIDES IN HUMAN THYROTROPIN - ROLE OF TERMINAL RESIDUES OF ALPHA-SUBUNIT AND BETA-SUBUNIT OLIGOSACCHARIDES IN METABOLIC-CLEARANCE AND BIOACTIVITY, Proceedings of the National Academy of Sciences of the United Statesof America, 92(20), 1995, pp. 9062-9066
EXPRESSION OF HUMAN THYROTROPIN IN CELL-LINES WITH DIFFERENT GLYCOSYLATION PATTERNS COMBINED WITH MUTAGENESIS OF SPECIFIC GLYCOSYLATION SITES - CHARACTERIZATION OF A NOVEL ROLE FOR THE OLIGOSACCHARIDES IN THE IN-VITRO AND IN-VIVO BIOACTIVITY
Authors: GROSSMANN M SZKUDLINSKI MW TROPEA JE BISHOP LA THOTAKURA NR SCHOFIELD PR WEINTRAUB BD
Citation: M. Grossmann et al., EXPRESSION OF HUMAN THYROTROPIN IN CELL-LINES WITH DIFFERENT GLYCOSYLATION PATTERNS COMBINED WITH MUTAGENESIS OF SPECIFIC GLYCOSYLATION SITES - CHARACTERIZATION OF A NOVEL ROLE FOR THE OLIGOSACCHARIDES IN THE IN-VITRO AND IN-VIVO BIOACTIVITY, The Journal of biological chemistry, 270(49), 1995, pp. 29378-29385
EFFECTS OF CONTINUOUS AND PULSATILE ADMINISTRATION OF PITUITARY RAT THYROTROPIN AND RECOMBINANT HUMAN THYROTROPIN IN A CHRONICALLY CANNULATED RAT
Authors: LEITOLF H SZKUDLINSKI MW HOANGVU C THOTAKURA NR VONZURMUHLEN A BRABANT G WEINTRAUB BD
Citation: H. Leitolf et al., EFFECTS OF CONTINUOUS AND PULSATILE ADMINISTRATION OF PITUITARY RAT THYROTROPIN AND RECOMBINANT HUMAN THYROTROPIN IN A CHRONICALLY CANNULATED RAT, Hormone and Metabolic Research, 27(4), 1995, pp. 173-178
RECOMBINANT THYROTROPIN CONTAINING A BETA-SUBUNIT CHIMERA WITH THE HUMAN CHORIONIC GONADOTROPIN-BETA CARBOXY-TERMINUS IS BIOLOGICALLY-ACTIVE, WITH A PROLONGED PLASMA HALF-LIFE - ROLE OF CARBOHYDRATE IN BIOACTIVITY AND METABOLIC-CLEARANCE
Authors: JOSHI L MURATA Y WONDISFORD FE SZKUDLINSKI MW DESAI R WEINTRAUB BD
Citation: L. Joshi et al., RECOMBINANT THYROTROPIN CONTAINING A BETA-SUBUNIT CHIMERA WITH THE HUMAN CHORIONIC GONADOTROPIN-BETA CARBOXY-TERMINUS IS BIOLOGICALLY-ACTIVE, WITH A PROLONGED PLASMA HALF-LIFE - ROLE OF CARBOHYDRATE IN BIOACTIVITY AND METABOLIC-CLEARANCE, Endocrinology, 136(9), 1995, pp. 3839-3848
ASPARAGINE-LINKED OLIGOSACCHARIDE STRUCTURES DETERMINE CLEARANCE AND ORGAN DISTRIBUTION OF PITUITARY AND RECOMBINANT THYROTROPIN
Authors: SZKUDLINSKI MW THOTAKURA NR TROPEA JE GROSSMANN M WEINTRAUB BD
Citation: Mw. Szkudlinski et al., ASPARAGINE-LINKED OLIGOSACCHARIDE STRUCTURES DETERMINE CLEARANCE AND ORGAN DISTRIBUTION OF PITUITARY AND RECOMBINANT THYROTROPIN, Endocrinology, 136(8), 1995, pp. 3325-3330
STRUCTURE-FUNCTION STUDIES OF OLIGOSACCHARIDES OF RECOMBINANT HUMAN THYROTROPIN BY SEQUENTIAL DEGLYCOSYLATION AND RESIALYLATION
Authors: THOTAKURA NR SZKUDLINSKI MW WEINTRAUB BD
Citation: Nr. Thotakura et al., STRUCTURE-FUNCTION STUDIES OF OLIGOSACCHARIDES OF RECOMBINANT HUMAN THYROTROPIN BY SEQUENTIAL DEGLYCOSYLATION AND RESIALYLATION, Glycobiology, 4(4), 1994, pp. 525-533
PURIFICATION AND CHARACTERIZATION OF RECOMBINANT HUMAN THYROTROPIN (TSH) ISOFORMS PRODUCED BY CHINESE-HAMSTER OVARY CELLS - THE ROLE OF SIALYLATION AND SULFATION IN TSH BIOACTIVITY
Authors: SZKUDLINSKI MW THOTAKURA NR BUCCI I JOSHI LR TSAI A EASTPALMER J SHILOACH J WEINTRAUB BD
Citation: Mw. Szkudlinski et al., PURIFICATION AND CHARACTERIZATION OF RECOMBINANT HUMAN THYROTROPIN (TSH) ISOFORMS PRODUCED BY CHINESE-HAMSTER OVARY CELLS - THE ROLE OF SIALYLATION AND SULFATION IN TSH BIOACTIVITY, Endocrinology, 133(4), 1993, pp. 1490-1503
Risultati: 1-16 |