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Results: 1-25 | 26-46
Results: 1-25/46
Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum
Authors: Sekine-Aizawa, Y Hama, E Watanabe, K Tsubuki, S Kanai-Azuma, M Kanai, Y Arai, H Aizawa, H Iwata, N Saido, TC
Citation: Y. Sekine-aizawa et al., Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum, EUR J NEURO, 13(5), 2001, pp. 935-948
Temporospatial sequence of cellular events associated with etoposide-induced neuronal cell death: Role of antiapoptotic protein Bcl-X-L
Authors: Kim, JE Han, BS Choi, WS Eom, DS Lee, EH Oh, TH Markelonis, GJ Saido, TC Lee, GE Chung, IK Oh, YJ
Citation: Je. Kim et al., Temporospatial sequence of cellular events associated with etoposide-induced neuronal cell death: Role of antiapoptotic protein Bcl-X-L, J NEUROSC R, 66(6), 2001, pp. 1074-1082
Age-dependent changes in brain, CSF, and plasma amyloid beta protein in the Tg2576 transgenic mouse model of Alzheimer's disease
Authors: Kawarabayashi, T Younkin, LH Saido, TC Shoji, M Ashe, KH Younkin, SG
Citation: T. Kawarabayashi et al., Age-dependent changes in brain, CSF, and plasma amyloid beta protein in the Tg2576 transgenic mouse model of Alzheimer's disease, J NEUROSC, 21(2), 2001, pp. 372-381
N-terminal truncated amyloid beta-peptides and Alzheimer's disease - Reply
Authors: Russo, C Schettini, G Saido, TC Gambetti, P Tabaton, M Teller, JT
Citation: C. Russo et al., N-terminal truncated amyloid beta-peptides and Alzheimer's disease - Reply, NEUROBIOL A, 22(3), 2001, pp. 345-345
Metabolic regulation of brain A beta by neprilysin
Authors: Iwata, N Tsubuki, S Takaki, Y Shirotani, K Lu, B Gerard, NP Gerard, C Hama, E Lee, HJ Saido, TC
Citation: N. Iwata et al., Metabolic regulation of brain A beta by neprilysin, SCIENCE, 292(5521), 2001, pp. 1550-1552
Alzheimer's disease - Molecular consequences of presenilin-1 mutation - Reply
Authors: Russo, C Schettini, G Saido, TC Hulette, C Lippa, C Lannfelt, L Ghetti, B Gambetti, P Tabaton, M Teller, JK
Citation: C. Russo et al., Alzheimer's disease - Molecular consequences of presenilin-1 mutation - Reply, NATURE, 411(6838), 2001, pp. 655-656
Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase
Authors: Kitazume, S Tachida, Y Oka, R Shirotani, K Saido, TC Hashimoto, Y
Citation: S. Kitazume et al., Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase, P NAS US, 98(24), 2001, pp. 13554-13559
Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2
Authors: Choi, WS Lee, EH Chung, CW Jung, YK Jin, BK Kim, SU Oh, TH Saido, TC Oh, YJ
Citation: Ws. Choi et al., Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2, J NEUROCHEM, 77(6), 2001, pp. 1531-1541
Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases
Authors: Shirotani, K Tsubuki, S Iwata, N Takaki, Y Harigaya, W Maruyama, K Kiryu-Seo, S Kiyama, H Iwata, H Tomita, T Iwatsubo, T Saido, TC
Citation: K. Shirotani et al., Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases, J BIOL CHEM, 276(24), 2001, pp. 21895-21901
Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons
Authors: Hama, E Shirotani, K Masumoto, H Sekine-Aizawa, Y Aizawa, H Saido, TC
Citation: E. Hama et al., Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons, J BIOCHEM, 130(6), 2001, pp. 721-726
Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains
Authors: Taniguchi, S Fujita, Y Hayashi, S Kakita, A Takahashi, H Murayama, S Saido, TC Hisanaga, S Iwatsubo, T Hasegawa, M
Citation: S. Taniguchi et al., Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains, FEBS LETTER, 489(1), 2001, pp. 46-50
Calpain-dependent proteolysis of merlin occurs by oxidative stress in meningiomas - A novel hypothesis of tumorigenesis
Authors: Kaneko, T Yamashima, T Tohma, Y Nomura, M Imajoh-Ohmi, S Saido, TC Nakao, M Saya, H Yamamoto, H Yamashita, J
Citation: T. Kaneko et al., Calpain-dependent proteolysis of merlin occurs by oxidative stress in meningiomas - A novel hypothesis of tumorigenesis, CANCER, 92(10), 2001, pp. 2662-2672
Molecular interactions between presenilin and calpain: Inhibition of m-calpain protease activity by presenilin-1, 2 and cleavage of presenilin-1 by m-, mu-calpain
Authors: Maruyama, K Usami, M Kametani, F Tomita, T Iwatsubo, T Saido, TC Mori, H Ishiura, S
Citation: K. Maruyama et al., Molecular interactions between presenilin and calpain: Inhibition of m-calpain protease activity by presenilin-1, 2 and cleavage of presenilin-1 by m-, mu-calpain, INT J MOL M, 5(3), 2000, pp. 269-273
Clearance of amyloid beta-peptide from brain: transport or metabolism? Reply
Authors: Iwata, N Tsubuki, S Hama, E Takaki, Y Shirotani, K Saido, TC
Citation: N. Iwata et al., Clearance of amyloid beta-peptide from brain: transport or metabolism? Reply, NAT MED, 6(7), 2000, pp. 718-719
Identification of the major A beta(1-42)-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition
Authors: Iwata, N Tsubuki, S Takaki, Y Watanabe, K Sekiguchi, M Hosoki, E Kawashima-Morishima, M Lee, HJ Hama, E Sekine-Aizawa, Y Saido, TC
Citation: N. Iwata et al., Identification of the major A beta(1-42)-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition, NAT MED, 6(2), 2000, pp. 143-150
Metabolism of amyloid precursor protein in COS cells transfected with a beta-secretase candidate
Authors: Koike, H Kouchi, Z Kinouchi, T Maeda, T Sorimachi, H Saido, TC Maruyama, K Okuyama, A Suzuki, K Ishiura, S
Citation: H. Koike et al., Metabolism of amyloid precursor protein in COS cells transfected with a beta-secretase candidate, CYTOTECHNOL, 33(1-3), 2000, pp. 213-219
Autolysis of calpain large subunit inducing irreversible dissociation of stoichiometric heterodimer of calpain
Authors: Kitagaki, H Tomioka, S Yoshizawa, T Sorimachi, H Saido, TC Ishiura, S Suzuki, K
Citation: H. Kitagaki et al., Autolysis of calpain large subunit inducing irreversible dissociation of stoichiometric heterodimer of calpain, BIOS BIOT B, 64(4), 2000, pp. 689-695
Involvement of polyglutamine endolysis followed by pyroglutamate formationin the pathogenesis of triplet repeat/polyglutamine-expansion diseases
Authors: Saido, TC
Citation: Tc. Saido, Involvement of polyglutamine endolysis followed by pyroglutamate formationin the pathogenesis of triplet repeat/polyglutamine-expansion diseases, MED HYPOTH, 54(3), 2000, pp. 427-429
Molecular cloning and expression of aminopeptidase A isoforms from rat hippocampus
Authors: Lee, HJ Tomioka, M Takaki, Y Masumoto, H Saido, TC
Citation: Hj. Lee et al., Molecular cloning and expression of aminopeptidase A isoforms from rat hippocampus, BBA-GENE ST, 1493(1-2), 2000, pp. 273-278
PS-liposome and Ox-LDL bind to different sites of the immunodominant domain (#155-183) of CD36: A study with GS95, a new anti-CD36 monoclonal antibody
Authors: Yamaguchi, A Yamamoto, N Akamatsu, N Saido, TC Kaneda, M Umeda, M Tanoue, K
Citation: A. Yamaguchi et al., PS-liposome and Ox-LDL bind to different sites of the immunodominant domain (#155-183) of CD36: A study with GS95, a new anti-CD36 monoclonal antibody, THROMB RES, 97(5), 2000, pp. 317-326
Neurobiology - Presenilin-1 mutations in Alzheimer's disease
Authors: Russo, C Schettini, G Saido, TC Hulette, C Lippall, C Lannfelt, L Ghetti, B Gambetti, P Tabaton, M Teller, JK
Citation: C. Russo et al., Neurobiology - Presenilin-1 mutations in Alzheimer's disease, NATURE, 405(6786), 2000, pp. 531-532
Age-related amyloid beta protein accumulation induces cellular death and macrophage activation in transgenic mice
Authors: Shoji, M Kawarabayashi, T Sato, M Sasaki, A Saido, TC Matsubara, E Tomidokoro, Y Kanai, M Shizuka, M Ishiguro, K Ikeda, M Harigaya, Y Okamoto, K Hirai, S
Citation: M. Shoji et al., Age-related amyloid beta protein accumulation induces cellular death and macrophage activation in transgenic mice, J PATHOLOGY, 191(1), 2000, pp. 93-101
Evidence that beta 3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active
Authors: Bialkowska, K Kulkarni, S Du, XP Goll, DE Saido, TC Fox, JEB
Citation: K. Bialkowska et al., Evidence that beta 3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active, J CELL BIOL, 151(3), 2000, pp. 685-695
Activation of calpain I converts excitotoxic neuron death into a caspase-independent cell death
Authors: Lankiewicz, S Luetjens, CM Bui, NT Krohn, AJ Poppe, M Cole, GM Saido, TC Prehn, JHM
Citation: S. Lankiewicz et al., Activation of calpain I converts excitotoxic neuron death into a caspase-independent cell death, J BIOL CHEM, 275(22), 2000, pp. 17064-17071
Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain
Authors: Takaki, Y Iwata, N Tsubuki, S Taniguchi, S Toyoshima, S Lu, B Gerard, NP Gerard, C Lee, HJ Shirotani, K Saido, TC
Citation: Y. Takaki et al., Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain, J BIOCHEM, 128(6), 2000, pp. 897-902
Risultati: 1-25 | 26-46