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Results: 1-24 |
Results: 24
Effect of injection volume on the pharmacokinetics of oil particles and incorporated menatetrenone after intravenous injection as O/W lipid emulsionsin rats
Authors: Ueda, K Ishida, M Fujimoto, M Kawahara, Y Sakaeda, T Iwakawa, S
Citation: K. Ueda et al., Effect of injection volume on the pharmacokinetics of oil particles and incorporated menatetrenone after intravenous injection as O/W lipid emulsionsin rats, J DRUG TAR, 9(5), 2001, pp. 353-360
Conjugation with L-glutamate for in vivo brain drug delivery
Authors: Sakaeda, T Tada, Y Sugawara, T Ryu, T Hirose, F Yoshikawa, T Hirano, K Kupczyk-Subotkowska, L Siahaan, TJ Audus, KL Stella, VJ
Citation: T. Sakaeda et al., Conjugation with L-glutamate for in vivo brain drug delivery, J DRUG TAR, 9(1), 2001, pp. 23-37
Reversal effects of antifungal drugs on multidrug resistance in MDR1-overexpressing HeLa cells
Authors: Iida, N Takara, K Ohmoto, N Nakamura, T Kimura, T Wada, A Hirai, M Sakaeda, T Okumura, K
Citation: N. Iida et al., Reversal effects of antifungal drugs on multidrug resistance in MDR1-overexpressing HeLa cells, BIOL PHAR B, 24(9), 2001, pp. 1032-1036
Molecular and pharmacokinetic properties of 222 commercially available oral drugs in humans
Authors: Sakaeda, T Okamura, N Nagata, S Yagami, T Horinouchi, M Okumura, K Yamashita, F Hashida, M
Citation: T. Sakaeda et al., Molecular and pharmacokinetic properties of 222 commercially available oral drugs in humans, BIOL PHAR B, 24(8), 2001, pp. 935-940
Effect of serum triglyceride concentration on the fluctuation of whole blood concentration of cyclosporin A in patients
Authors: Nakamura, T Kakumoto, M Sakaeda, T Nagahiro, K Ohmichi, R Yamashita, K Nishiguchi, K Hirai, M Okumura, K
Citation: T. Nakamura et al., Effect of serum triglyceride concentration on the fluctuation of whole blood concentration of cyclosporin A in patients, BIOL PHAR B, 24(6), 2001, pp. 683-687
N-acetyltransferase2 genotype correlated with isoniazid acetylation in Japanese tuberculous patients
Authors: Kita, T Tanigawara, Y Chikazawa, S Hatanaka, H Sakaeda, T Komada, F Iwakawa, S Okumura, K
Citation: T. Kita et al., N-acetyltransferase2 genotype correlated with isoniazid acetylation in Japanese tuberculous patients, BIOL PHAR B, 24(5), 2001, pp. 544-549
Factors influencing the prediction of steady state concentrations of digoxin
Authors: Nakamura, T Kakumoto, M Yamashita, K Takara, K Tanigawara, Y Sakaeda, T Okumura, K
Citation: T. Nakamura et al., Factors influencing the prediction of steady state concentrations of digoxin, BIOL PHAR B, 24(4), 2001, pp. 403-408
N-acetyltransferase 2 genotype correlates with sulfasarazine pharmacokinetics after multiple dosing in healthy Japanese subjects
Authors: Kita, T Sakaeda, T Adachi, S Sakai, T Aoyama, N Hatanaka, H Kasuga, M Okumura, K
Citation: T. Kita et al., N-acetyltransferase 2 genotype correlates with sulfasarazine pharmacokinetics after multiple dosing in healthy Japanese subjects, BIOL PHAR B, 24(10), 2001, pp. 1176-1180
CYP2C19 genotype and pharmacokinetics of three proton pump inhibitors in healthy subjects
Authors: Sakai, T Aoyama, N Kita, T Sakaeda, T Nishiguchi, K Nishitora, Y Hohda, T Sirasaka, D Tamura, T Tanigawara, Y Kasuga, M Okumura, K
Citation: T. Sakai et al., CYP2C19 genotype and pharmacokinetics of three proton pump inhibitors in healthy subjects, PHARM RES, 18(6), 2001, pp. 721-727
CYP2C19 genotype related effect of omeprazole on intragastric pH and antimicrobial stability
Authors: Kita, T Tanigawara, Y Aoyama, N Hohda, T Saijoh, Y Komada, F Sakaeda, T Okumura, K Sakai, T Kasuga, M
Citation: T. Kita et al., CYP2C19 genotype related effect of omeprazole on intragastric pH and antimicrobial stability, PHARM RES, 18(5), 2001, pp. 615-621
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects
Authors: Sakaeda, T Nakamura, T Horinouchi, M Kakumoto, M Ohmoto, N Sakai, T Morita, Y Tamura, T Aoyama, N Hirai, M Kasuga, M Okumura, K
Citation: T. Sakaeda et al., MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects, PHARM RES, 18(10), 2001, pp. 1400-1404
Controlled release and ocular absorption of tilisolol utilizing ophthalmicinsert-incorporated lipophilic prodrugs
Authors: Kawakami, S Nishida, K Mukai, T Yamamura, K Nakamura, J Sakaeda, T Nakashima, M Sasaki, H
Citation: S. Kawakami et al., Controlled release and ocular absorption of tilisolol utilizing ophthalmicinsert-incorporated lipophilic prodrugs, J CONTR REL, 76(3), 2001, pp. 255-263
Identification of N-acetyltransferase 2 and CYP2C19 genotypes for hair, buccal cell swabs, or fingernails compared with blood
Authors: Tanigawara, Y Kita, T Hirono, M Sakaeda, T Komada, F Okumura, K
Citation: Y. Tanigawara et al., Identification of N-acetyltransferase 2 and CYP2C19 genotypes for hair, buccal cell swabs, or fingernails compared with blood, THER DRUG M, 23(4), 2001, pp. 341-346
Sustained ocular delivery of tilisolol to rabbits after topical administration or intravitreal injection of lipophilic prodrug incorporated in liposomes
Authors: Kawakami, S Yamamura, K Mukai, T Nishida, K Nakamura, J Sakaeda, T Nakashima, M Sasaki, H
Citation: S. Kawakami et al., Sustained ocular delivery of tilisolol to rabbits after topical administration or intravitreal injection of lipophilic prodrug incorporated in liposomes, J PHARM PHA, 53(8), 2001, pp. 1157-1161
Effects of S-2474, a novel nonsteroidal anti-inflammatory drug, on amyloidbeta protein-induced neuronal cell death
Authors: Yagami, T Ueda, K Asakura, K Sakaeda, T Kuroda, T Hata, S Kambayashi, Y Fujimoto, M
Citation: T. Yagami et al., Effects of S-2474, a novel nonsteroidal anti-inflammatory drug, on amyloidbeta protein-induced neuronal cell death, BR J PHARM, 134(3), 2001, pp. 673-681
Enhancement of transport of D-melphalan analogue by conjugation with L-glutamate across bovine brain microvessel endothelial cell monolayers
Authors: Sakaeda, T Siahaan, TJ Audus, KL Stella, VJ
Citation: T. Sakaeda et al., Enhancement of transport of D-melphalan analogue by conjugation with L-glutamate across bovine brain microvessel endothelial cell monolayers, J DRUG TAR, 8(3), 2000, pp. 195-204
The novel anticancer drug KRN5500 interacts with, but is hardly transported by, human P-glycoprotein
Authors: Takara, K Tanigawara, Y Komada, F Nishiguchi, K Sakaeda, T Okumura, K
Citation: K. Takara et al., The novel anticancer drug KRN5500 interacts with, but is hardly transported by, human P-glycoprotein, JPN J CANC, 91(2), 2000, pp. 248-254
Cellular pharmacokinetic aspects of reversal effect of itraconazole on P-glycoprotein-mediated resistance of anticancer drugs
Authors: Takara, K Tanigawara, Y Komada, F Nishiguchi, K Sakaeda, T Okumura, K
Citation: K. Takara et al., Cellular pharmacokinetic aspects of reversal effect of itraconazole on P-glycoprotein-mediated resistance of anticancer drugs, BIOL PHAR B, 22(12), 1999, pp. 1355-1359
Interaction of docetaxel ("Taxotere") with human P-glycoprotein
Authors: Shirakawa, K Takara, K Tanigawara, Y Aoyama, N Kasuga, M Komada, F Sakaeda, T Okumura, K
Citation: K. Shirakawa et al., Interaction of docetaxel ("Taxotere") with human P-glycoprotein, JPN J CANC, 90(12), 1999, pp. 1380-1386
A novel chemical delivery system for brain targeting
Authors: Yoshikawa, T Sakaeda, T Sugawara, T Hirano, K Stella, VJ
Citation: T. Yoshikawa et al., A novel chemical delivery system for brain targeting, ADV DRUG DE, 36(2-3), 1999, pp. 255-275
Blood flow rate in normal and tumor-bearing rats in conscious state, underurethane anesthesia, and during systemic hypothermia
Authors: Sakaeda, T Fukumura, K Takahashi, K Matsumura, S Matsuura, E Hirano, K
Citation: T. Sakaeda et al., Blood flow rate in normal and tumor-bearing rats in conscious state, underurethane anesthesia, and during systemic hypothermia, J DRUG TAR, 6(4), 1998, pp. 261-272
Effect of composition on biological fate of oil particles after intravenous injection of O/W lipid emulsions
Authors: Sakaeda, T Hirano, K
Citation: T. Sakaeda et K. Hirano, Effect of composition on biological fate of oil particles after intravenous injection of O/W lipid emulsions, J DRUG TAR, 6(4), 1998, pp. 273-284
O/W lipid emulsions for parenteral drug delivery. IV. Changes in the pharmacokinetics and pharmacodynamics of a highly lipophilic drug, menatetrenone
Authors: Sakaeda, T Kakushi, H Shike, T Takano, K Harauchi, T Hirata, M Hirano, K
Citation: T. Sakaeda et al., O/W lipid emulsions for parenteral drug delivery. IV. Changes in the pharmacokinetics and pharmacodynamics of a highly lipophilic drug, menatetrenone, J DRUG TAR, 6(3), 1998, pp. 183-189
O/W lipid emulsions for parenteral drug delivery. III. Lipophilicity necessary for incorporation in oil particles even after intravenous injection
Authors: Sakaeda, T Hirano, K
Citation: T. Sakaeda et K. Hirano, O/W lipid emulsions for parenteral drug delivery. III. Lipophilicity necessary for incorporation in oil particles even after intravenous injection, J DRUG TAR, 6(2), 1998, pp. 119-127
Risultati: 1-24 |