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Results: 1-12 |
Results: 12
Convertases other than furin cleave beta-secretase to its mature form
Authors: Pinnix, I Council, JE Roseberry, B Onstead, L Mallender, W Sucic, J Sambamurti, K
Citation: I. Pinnix et al., Convertases other than furin cleave beta-secretase to its mature form, FASEB J, 15(8), 2001, pp. NIL_515-NIL_532
Reduction of A beta accumulation in the Tg2576 animal model of Alzheimer'sdisease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin
Authors: Haugabook, SJ Le, T Yager, D Zenk, B Healy, BM Eckman, EA Prada, C Younkin, L Murphy, P Pinnix, I Onstead, L Sambamurti, K Golde, TE Dickson, D Younkin, SG Eckman, CB
Citation: Sj. Haugabook et al., Reduction of A beta accumulation in the Tg2576 animal model of Alzheimer'sdisease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin, FASEB J, 15(1), 2001, pp. 16-18
Phenserine regulates translation of beta-amyloid precursor protein mRNA bya putative interleukin-1 responsive element, a target for drug development
Authors: Shaw, KTY Utsuki, T Rogers, J Yu, QS Sambamurti, K Brossi, A Ge, YW Lahiri, DK Greig, NH
Citation: Kty. Shaw et al., Phenserine regulates translation of beta-amyloid precursor protein mRNA bya putative interleukin-1 responsive element, a target for drug development, P NAS US, 98(13), 2001, pp. 7605-7610
Characterization of recombinant, soluble beta-secretase from an insect cell expression system
Authors: Mallender, WD Yager, D Onstead, L Nichols, MR Eckman, C Sambamurti, K Kopcho, LM Marcinkeviciene, J Copeland, RA Rosenberry, TL
Citation: Wd. Mallender et al., Characterization of recombinant, soluble beta-secretase from an insect cell expression system, MOLEC PHARM, 59(3), 2001, pp. 619-626
A novel gamma-secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor
Authors: Pinnix, I Musunuru, U Tun, H Sridharan, A Golde, T Eckman, C Ziani-Cherif, C Onstead, L Sambamurti, K
Citation: I. Pinnix et al., A novel gamma-secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor, J BIOL CHEM, 276(1), 2001, pp. 481-487
A high fat, high cholesterol diet accelerates beta-amyloid accumulation inthe CNS of a transgenic mouse model of Alzheimer's disease
Authors: Refolo, LM Malester, B LaFrancois, J Bryant-Thomas, T Wang, R Tint, GS Sambamurti, K Duff, K Pappolla, MA
Citation: Lm. Refolo et al., A high fat, high cholesterol diet accelerates beta-amyloid accumulation inthe CNS of a transgenic mouse model of Alzheimer's disease, ALZHEIMER'S DISEASE, 2001, pp. 433-447
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model (vol 7, pg 321, 2000)
Authors: Refolo, LM Pappolla, MA Malester, B LaFrancois, J Bryant-Thomas, T Wang, R Tint, GS Sambamurti, K Duff, K
Citation: Lm. Refolo et al., Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model (vol 7, pg 321, 2000), NEUROBIOL D, 7(6), 2000, pp. 690-691
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
Authors: Refolo, LM Pappolla, MA Malester, B LaFrancois, J Bryant-Thomas, T Wang, R Tint, GS Sambamurti, K Duff, K
Citation: Lm. Refolo et al., Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model, NEUROBIOL D, 7(4), 2000, pp. 321-331
Cell-free assays for gamma-secretase activity
Authors: McLendon, C Xin, TP Ziani-Cherif, C Murphy, MP Findlay, KA Lewis, PA Pinnix, I Sambamurti, K Wang, R Fauq, A Golde, TE
Citation: C. Mclendon et al., Cell-free assays for gamma-secretase activity, FASEB J, 14(15), 2000, pp. 2383-2386
Glycosylphosphatidylinositol-anchor intermediates associate with Triton-insoluble membranes in subcellular compartments that include the endoplasmic reticulum
Authors: Sevlever, D Pickett, S Mann, KJ Sambamurti, K Medof, ME Rosenberry, TL
Citation: D. Sevlever et al., Glycosylphosphatidylinositol-anchor intermediates associate with Triton-insoluble membranes in subcellular compartments that include the endoplasmic reticulum, BIOCHEM J, 343, 1999, pp. 627-635
Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta 42 in transfected cells
Authors: Refolo, LM Eckman, C Prada, CM Yager, D Sambamurti, K Mehta, N Hardy, J Younkin, SG
Citation: Lm. Refolo et al., Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta 42 in transfected cells, J NEUROCHEM, 73(6), 1999, pp. 2383-2388
Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein
Authors: Sambamurti, K Sevlever, D Koothan, T Refolo, LM Pinnix, I Gandhi, S Onstead, L Younkin, L Prada, CM Yager, D Ohyagi, Y Eckman, CB Rosenberry, TL Younkin, SG
Citation: K. Sambamurti et al., Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein, J BIOL CHEM, 274(38), 1999, pp. 26810-26814
Risultati: 1-12 |