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Results: 1-25 | 26-50 | 51-56
Results: 1-25/56
Anti-HBV specific beta-L-2 '-deoxynucleosides
Authors: Bryant, ML Bridges, EG Placidi, L Faraj, A Loi, AG Pierra, C Dukhan, D Gosselin, G Imbach, JL Hernandez, B Juodawlkis, A Tennant, B Korba, B Cote, P Cretton-Scott, E Schinazi, RF Sommadossi, JP
Citation: Ml. Bryant et al., Anti-HBV specific beta-L-2 '-deoxynucleosides, NUCLEOS NUC, 20(4-7), 2001, pp. 597-607
Asymmetric synthesis of carbocyclic pyrimidine nucleosides via pi-allylpalladium complex
Authors: Shi, JX Schinazi, RF
Citation: Jx. Shi et Rf. Schinazi, Asymmetric synthesis of carbocyclic pyrimidine nucleosides via pi-allylpalladium complex, NUCLEOS NUC, 20(4-7), 2001, pp. 1367-1370
Enhancement of the bioavailability of oral uridine by coadministration of 5-(phenylthio) acyclouridine, a uridine phosphorylase inhibitor: implications for uridine rescue regimens in chemotherapy
Authors: Al Safarjalani, ON Zhou, XJ Naguib, FNM Shi, JX Schinazi, RF el Kouni, MH
Citation: On. Al Safarjalani et al., Enhancement of the bioavailability of oral uridine by coadministration of 5-(phenylthio) acyclouridine, a uridine phosphorylase inhibitor: implications for uridine rescue regimens in chemotherapy, CANC CHEMOT, 48(5), 2001, pp. 389-397
Modulation of the pharmacokinetics of endogenous plasma uridine by 5-(phenylthio) acyclouridine, a uridine phosphorylase inhibitor: implications for chemotherapy
Authors: Al Safarjalani, ON Zhou, XJ Naguib, FNM Goudgaon, NM Schinazi, RF el Kouni, MH
Citation: On. Al Safarjalani et al., Modulation of the pharmacokinetics of endogenous plasma uridine by 5-(phenylthio) acyclouridine, a uridine phosphorylase inhibitor: implications for chemotherapy, CANC CHEMOT, 48(2), 2001, pp. 145-150
Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region
Authors: Stuyver, LJ Locarnini, SA Lok, A Richman, DD Carman, WF Dienstag, JL Schinazi, RF
Citation: Lj. Stuyver et al., Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region, HEPATOLOGY, 33(3), 2001, pp. 751-757
Dynamic SIMS ion microscopy imaging of intracellular boron accumulation from carboranyl nucleosides in glioma cells
Authors: Gay, I Lorey, DR Schinazi, RF Morrison, GH Chandra, S
Citation: I. Gay et al., Dynamic SIMS ion microscopy imaging of intracellular boron accumulation from carboranyl nucleosides in glioma cells, ANTICANC R, 21(4A), 2001, pp. 2369-2375
Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine
Authors: Furman, PA Jeffrey, J Keifer, LL Feng, JY Anderson, KS Borroto-Esoda, K Hill, E Copeland, WC Chu, CK Sommadossi, JP Liberman, I Schinazi, RF Painter, GR
Citation: Pa. Furman et al., Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine, ANTIM AG CH, 45(1), 2001, pp. 158-165
Antiviral L-nucleosides specific for hepatitis B virus infection
Authors: Bryant, ML Bridges, EG Placidi, L Faraj, A Loi, AG Pierra, C Dukhan, D Gosselin, G Imbach, JL Hernandez, B Juodawlkis, A Tennant, B Korba, B Cote, P Marion, P Cretton-Scott, E Schinazi, RF Sommadossi, JP
Citation: Ml. Bryant et al., Antiviral L-nucleosides specific for hepatitis B virus infection, ANTIM AG CH, 45(1), 2001, pp. 229-235
Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus
Authors: Song, GY Paul, V Choo, H Morrey, J Sidwell, RW Schinazi, RF Chu, CK
Citation: Gy. Song et al., Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus, J MED CHEM, 44(23), 2001, pp. 3985-3993
Cellular replication of human immunodeficiency virus type 1 occurs in vaginal secretions
Authors: Ellerbrock, TV Lennox, JL Clancy, KA Schinazi, RF Wright, TC Pratt-Palmore, M Evans-Strickfaden, T Schnell, C Pai, R Conley, LJ Parrish-Kohler, EE Bush, TJ Tatti, K Hart, CE
Citation: Tv. Ellerbrock et al., Cellular replication of human immunodeficiency virus type 1 occurs in vaginal secretions, J INFEC DIS, 184(1), 2001, pp. 28-36
The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance
Authors: Ono, SK Kato, N Shiratori, Y Kato, J Goto, T Schinazi, RF Carrilho, FJ Omata, M
Citation: Sk. Ono et al., The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance, J CLIN INV, 107(4), 2001, pp. 449-455
Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition
Authors: Judd, DA Nettles, JH Nevins, N Snyder, JP Liotta, DC Tang, J Ermolieff, J Schinazi, RF Hill, CL
Citation: Da. Judd et al., Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition, J AM CHEM S, 123(5), 2001, pp. 886-897
Cellular pharmacology of the D- and L-enantiomers of beta-5-o-carboranyl-2'-deoxyuridine
Authors: Hurwitz, SJ Ma, L Eleuteri, A Wright, J Moravek, J Schinazi, RF
Citation: Sj. Hurwitz et al., Cellular pharmacology of the D- and L-enantiomers of beta-5-o-carboranyl-2'-deoxyuridine, NUCLEOS NUC, 19(3), 2000, pp. 691-702
Synthesis and antiviral activities of enantiomeric 1-[2-(hydroxymethyl)cyclopropyl] methyl nucleosides
Authors: Pierra, C Olgen, S Cavalcanti, SCH Cheng, YC Schinazi, RF Chu, CK
Citation: C. Pierra et al., Synthesis and antiviral activities of enantiomeric 1-[2-(hydroxymethyl)cyclopropyl] methyl nucleosides, NUCLEOS NUC, 19(1-2), 2000, pp. 253-268
In vitro and in vivo metabolism and pharmacokinetics of bis [(T-butyl)-S-acyl-2-thioethyl]-beta-1-2 ',3 '-dideoxy-5-fluorocytidine monophosphate
Authors: Martin, LT Cretton-Scott, E Placidi, L Faraj, A Loi, AG Schinazi, RF McClure, HM Gosselin, G Imbach, JL Sommadossi, JP
Citation: Lt. Martin et al., In vitro and in vivo metabolism and pharmacokinetics of bis [(T-butyl)-S-acyl-2-thioethyl]-beta-1-2 ',3 '-dideoxy-5-fluorocytidine monophosphate, NUCLEOS NUC, 19(1-2), 2000, pp. 481-499
Treatment of isografted 9L rat brain tumors with beta-5-o-carboranyl-2 '-deoxyuridine neutron capture therapy
Authors: Schinazi, RF Hurwitz, SJ Liberman, I Juodawlkis, AS Tharnish, P Shi, JX Liotta, DC Coderre, JA Olson, J
Citation: Rf. Schinazi et al., Treatment of isografted 9L rat brain tumors with beta-5-o-carboranyl-2 '-deoxyuridine neutron capture therapy, CLIN CANC R, 6(2), 2000, pp. 725-730
Effect of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on plasma concentration of uridine released from 2 ',3 ',5 '-tri-O-acetyluridine, a prodrug of uridine: relevance to uridine rescue in chemotherapy
Authors: Ashour, OM Naguib, FNM Goudgaon, NM Schinazi, RF el Kouni, MH
Citation: Om. Ashour et al., Effect of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on plasma concentration of uridine released from 2 ',3 ',5 '-tri-O-acetyluridine, a prodrug of uridine: relevance to uridine rescue in chemotherapy, CANC CHEMOT, 46(3), 2000, pp. 235-240
Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase: relevance to chemotherapy
Authors: Ashour, OM Al Safarjalani, ON Naguib, FNM Goudgaon, NM Schinazi, RF el Kouni, MH
Citation: Om. Ashour et al., Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase: relevance to chemotherapy, CANC CHEMOT, 45(5), 2000, pp. 351-361
Mololipids, a new series of anti-HIV bromotyramine-derived compounds from a sponge of the order Verongida
Authors: Ross, SA Weete, JD Schinazi, RF Wirtz, SS Tharnish, P Scheuer, PJ Hamann, MT
Citation: Sa. Ross et al., Mololipids, a new series of anti-HIV bromotyramine-derived compounds from a sponge of the order Verongida, J NAT PROD, 63(4), 2000, pp. 501-503
In vitro selection of mutations in the human immunodeficiency virus type 1reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3 '-azido-3 '-deoxythymidine
Authors: Bazmi, HZ Hammond, JL Cavalcanti, SCH Chu, CK Schinazi, RF Mellors, JW
Citation: Hz. Bazmi et al., In vitro selection of mutations in the human immunodeficiency virus type 1reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3 '-azido-3 '-deoxythymidine, ANTIM AG CH, 44(7), 2000, pp. 1783-1788
Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucks
Authors: Korba, BE Schinazi, RF Cote, P Tennant, BC Gerin, JL
Citation: Be. Korba et al., Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucks, ANTIM AG CH, 44(6), 2000, pp. 1757-1760
Intracellular metabolism of beta-L-2 ',3 '-dideoxyadenosine: Relevance to its limited antiviral activity
Authors: Placidi, L Cretton-Scott, E Gosselin, G Pierra, C Schinazi, RF Imbach, JL El Kouni, M Sommadossi, JP
Citation: L. Placidi et al., Intracellular metabolism of beta-L-2 ',3 '-dideoxyadenosine: Relevance to its limited antiviral activity, ANTIM AG CH, 44(4), 2000, pp. 853-858
Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2 '-deoxynucleoside triphosphates
Authors: Meyer, PR Matsuura, SE Schinazi, RF So, AG Scott, WA
Citation: Pr. Meyer et al., Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2 '-deoxynucleoside triphosphates, ANTIM AG CH, 44(12), 2000, pp. 3465-3472
Human herpesvirus 8 open reading frame 21 is a thymidine and thymidylate kinase of narrow substrate specificity that efficiently phosphorylates zidovudine but not ganciclovir
Authors: Gustafson, EA Schinazi, RF Fingeroth, JD
Citation: Ea. Gustafson et al., Human herpesvirus 8 open reading frame 21 is a thymidine and thymidylate kinase of narrow substrate specificity that efficiently phosphorylates zidovudine but not ganciclovir, J VIROLOGY, 74(2), 2000, pp. 684-692
Synthesis and antiviral activity of oxaselenolane nucleosides
Authors: Chu, CK Ma, L Olgen, S Pierra, C Du, JF Gumina, G Gullen, E Cheng, YC Schinazi, RF
Citation: Ck. Chu et al., Synthesis and antiviral activity of oxaselenolane nucleosides, J MED CHEM, 43(21), 2000, pp. 3906-3912
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