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Results: 1-5 |
Results: 5
De novo design of a novel oxazolidinone analogue as a potent and selectivealpha(1A) adrenergic receptor antagonist with high oral bioavailability
Authors: Lagu, B Tian, D Jeon, Y Li, C Wetzel, JM Nagarathnam, D Shen, QR Forray, C Chang, RSL Broten, TP Ransom, RW Chan, TB O'Malley, SS Schorn, TW Rodrigues, AD Kassahun, K Pettibone, DJ Freidinger, R Gluchowski, C
Citation: B. Lagu et al., De novo design of a novel oxazolidinone analogue as a potent and selectivealpha(1A) adrenergic receptor antagonist with high oral bioavailability, J MED CHEM, 43(15), 2000, pp. 2775-2778
In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia
Authors: Barrow, JC Nantermet, PG Selnick, HG Glass, KL Rittle, KE Gilbert, KF Steele, TG Homnick, CF Freidinger, RM Ransom, RW Kling, P Reiss, D Broten, TP Schorn, TW Chang, RSL O'Malley, SS Olah, TV Ellis, JD Barrish, A Kassahun, K Leppert, P Nagarathnam, D Forray, C
Citation: Jc. Barrow et al., In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia, J MED CHEM, 43(14), 2000, pp. 2703-2718
Design and synthesis of novel alpha(1a) adrenoceptor-selective antagonists. 1. Structure-activity relationship in dihydropyrimidinones
Authors: Nagarathnam, D Miao, SW Lagu, B Chiu, G Fang, J Dhar, TGM Zhang, J Tyagarajan, S Marzabadi, MR Zhang, FQ Wong, WC Sun, WY Tian, D Wetzel, JM Forray, C Chang, RSL Broten, TP Ransom, RW Schorn, TW Chen, TB O'Malley, S Kling, P Schneck, K Bendesky, R Harrell, CM Vyas, KP Gluchowski, C
Citation: D. Nagarathnam et al., Design and synthesis of novel alpha(1a) adrenoceptor-selective antagonists. 1. Structure-activity relationship in dihydropyrimidinones, J MED CHEM, 42(23), 1999, pp. 4764-4777
Design and synthesis of novel alpha(1a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification oflinker and 4-methoxycarbonyl-4-phenylpiperidine moiety
Authors: Dhar, TGM Nagarathnam, D Marzabadi, MR Lagu, B Wong, WC Chiu, G Tyagarajan, S Miao, SW Zhang, FQ Sun, WY Tian, D Shen, QR Zhang, J Wetzel, JM Forray, C Chang, RSL Broten, TP Schorn, TW Chen, TB O'Malley, S Ransom, R Schneck, K Bendesky, R Harrell, CM Vyas, KP Zhang, KY Gilbert, J Pettibone, DJ Patane, MA Bock, MG Freidinger, RM Gluchowski, C
Citation: Tgm. Dhar et al., Design and synthesis of novel alpha(1a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification oflinker and 4-methoxycarbonyl-4-phenylpiperidine moiety, J MED CHEM, 42(23), 1999, pp. 4778-4793
Design and synthesis of novel alpha(1a) adrenoceptor-selective dihydropyridine antagonists for the treatment of benign prostatic hyperplasia
Authors: Nagarathnam, D Wetzel, JM Miao, SW Marzabadi, MR Chiu, G Wong, WC Hong, XF Fang, J Forray, C Branchek, TA Heydorn, WE Chang, RSL Broten, T Schorn, TW Gluchowski, C
Citation: D. Nagarathnam et al., Design and synthesis of novel alpha(1a) adrenoceptor-selective dihydropyridine antagonists for the treatment of benign prostatic hyperplasia, J MED CHEM, 41(26), 1998, pp. 5320-5333
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