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Results: 1-17 |
Results: 17
The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants
Authors: Zhang, J Kuehl, P Green, ED Touchman, JW Watkins, PB Daly, A Hall, SD Maurel, P Relling, M Brimer, C Yasuda, K Wrighton, SA Hancock, M Kim, RB Strom, S Thummel, K Russell, CG Hudson, JR Schuetz, EG Boguski, MS
Citation: J. Zhang et al., The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants, PHARMACOGEN, 11(7), 2001, pp. 555-572
Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo
Authors: Lecureur, V Thottassery, JV Sun, D Schuetz, EG Lahti, J Zambetti, GP Schuetz, JD
Citation: V. Lecureur et al., Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo, ONCOGENE, 20(3), 2001, pp. 303-313
The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia
Authors: van de Poll, MEC Relling, MV Schuetz, EG Harrison, PL Hughes, W Flynn, PM
Citation: Mec. Van De Poll et al., The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia, CANC CHEMOT, 47(6), 2001, pp. 467-472
Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome p450
Authors: Schuetz, EG Strom, S Yasuda, K Lecureur, V Assem, M Brimer, C Lamba, J Kim, RB Ramachandran, V Komoroski, BJ Venkataramanan, R Cai, HB Sinal, CJ Gonzalez, FJ Schuetz, JD
Citation: Eg. Schuetz et al., Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome p450, J BIOL CHEM, 276(42), 2001, pp. 39411-39418
Identification of functionally variant MDR1 alleles among European Americans and African Americans
Authors: Kim, RB Leake, BF Choo, EF Dresser, GK Kubba, SV Schwarz, UI Taylor, A Xie, HG McKinsey, J Zhou, S Lan, LB Schuetz, JD Schuetz, EG Wilkinson, GR
Citation: Rb. Kim et al., Identification of functionally variant MDR1 alleles among European Americans and African Americans, CLIN PHARM, 70(2), 2001, pp. 189-199
Need and potential for predictive tests of hepatic metabolism of anticancer drugs
Authors: Stewart, CF Schuetz, EG
Citation: Cf. Stewart et Eg. Schuetz, Need and potential for predictive tests of hepatic metabolism of anticancer drugs, CLIN CANC R, 6(9), 2000, pp. 3391-3392
Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein
Authors: Brimer, C Dalton, JT Zhu, ZX Schuetz, J Yasuda, K Vanin, E Relling, MV Lu, Y Schuetz, EG
Citation: C. Brimer et al., Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein, PHARM RES, 17(7), 2000, pp. 803-810
The human CYP3A subfamily: Practical considerations
Authors: Wrighton, SA Schuetz, EG Thummel, KE Shen, DD Korzekwa, KR Watkins, PB
Citation: Sa. Wrighton et al., The human CYP3A subfamily: Practical considerations, DRUG METAB, 32(3-4), 2000, pp. 339-361
Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia
Authors: Relling, MV Pui, CH Sandlund, JT Rivera, GK Hancock, ML Boyett, JM Schuetz, EG Evans, WE
Citation: Mv. Relling et al., Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia, LANCET, 356(9226), 2000, pp. 285-290
The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver
Authors: Schuetz, EG Schmid, W Schutz, G Brimer, C Yasuda, K Kamataki, T Bornheim, L Myles, K Cole, TJ
Citation: Eg. Schuetz et al., The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver, DRUG META D, 28(3), 2000, pp. 268-278
Mdr1 limits CYP3A metabolism in vivo
Authors: Lan, LB Dalton, JT Schuetz, EG
Citation: Lb. Lan et al., Mdr1 limits CYP3A metabolism in vivo, MOLEC PHARM, 58(4), 2000, pp. 863-869
Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes. (vol 57, pg 188, 2000)
Authors: Schuetz, EG Umbenhauer, DR Yasuda, K Brimer, C Nguyen, L Relling, MV Schuetz, JD Schinkel, AH
Citation: Eg. Schuetz et al., Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes. (vol 57, pg 188, 2000), MOLEC PHARM, 57(6), 2000, pp. NIL_1-NIL_1
Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein
Authors: Lecureur, V Sun, DX Hargrove, P Schuetz, EG Kim, RB Lan, LB Schuetz, JD
Citation: V. Lecureur et al., Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein, MOLEC PHARM, 57(1), 2000, pp. 24-35
Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes
Authors: Schuetz, EG Umbenhauer, DR Yasuda, K Brimer, C Nguyen, L Relling, MV Schuetz, JD Schinkel, AH
Citation: Eg. Schuetz et al., Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes, MOLEC PHARM, 57(1), 2000, pp. 188-197
Sp1 and Egr-1 have opposing effects on the regulation of the rat pgp2/mdr1b gene
Authors: Thottassery, JV Sun, DX Zambetti, GP Troutman, A Sukhatme, VP Schuetz, EG Schuetz, JD
Citation: Jv. Thottassery et al., Sp1 and Egr-1 have opposing effects on the regulation of the rat pgp2/mdr1b gene, J BIOL CHEM, 274(5), 1999, pp. 3199-3206
6 ',7 '-Dihydroxybergamottin in grapefruit juice and Seville orange juice:Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein
Authors: Edwards, DJ Fitzsimmons, ME Schuetz, EG Yasuda, K Ducharme, MP Warbasse, LH Woster, PM Schuetz, JD Watkins, P
Citation: Dj. Edwards et al., 6 ',7 '-Dihydroxybergamottin in grapefruit juice and Seville orange juice:Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein, CLIN PHARM, 65(3), 1999, pp. 237-244
Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate theCYP3A23 hormone response element
Authors: Schuetz, EG Brimer, C Schuetz, JD
Citation: Eg. Schuetz et al., Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate theCYP3A23 hormone response element, MOLEC PHARM, 54(6), 1998, pp. 1113-1117
Risultati: 1-17 |