Authors:
Djeha, AH
Thomson, TA
Leung, H
Searle, PF
Young, LS
Kerr, DJ
Harris, PA
Mountain, A
Wrighton, CJ
Citation: Ah. Djeha et al., Combined adenovirus-mediated nitroreductase gene delivery and CB1954 treatment: A well-tolerated therapy for established solid tumors, MOL THER, 3(2), 2001, pp. 233-240
Authors:
Lipinski, KS
Djeha, AH
Krausz, E
Lane, DP
Searle, PF
Mountain, A
Wrighton, CJ
Citation: Ks. Lipinski et al., Tumour-specific therapeutic adenovirus vectors: repression of transgene expression in healthy cells by endogenous p53, GENE THER, 8(4), 2001, pp. 274-281
Authors:
Chung-Faye, GA
Chen, MJ
Green, NK
Burton, A
Anderson, D
Mautner, V
Searle, PF
Kerr, DJ
Citation: Ga. Chung-faye et al., In vivo gene therapy for colon cancer using adenovirus-mediated, transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase, GENE THER, 8(20), 2001, pp. 1547-1554
Authors:
Lovering, AL
Hyde, EI
Searle, PF
Scott, AW
Citation: Al. Lovering et al., The structure of Escherichia coli nitroreductase complexed with nicotinic acid: Three crystal forms at 1.7 (A)over-circle, 1.8 (A)over-circle and 2.4(A)over-circle resolution, J MOL BIOL, 309(1), 2001, pp. 203-213
Authors:
Djeha, AH
Hulme, A
Dexter, MT
Mountain, A
Young, LS
Searle, PF
Kerr, DJ
Wrighton, CJ
Citation: Ah. Djeha et al., Expression of Escherichia coli B nitroreductase in established human tumorxenografts in mice results in potent antitumoral and bystander effects upon systemic administration of the prodrug CB1954, CANC GENE T, 7(5), 2000, pp. 721-731
Authors:
Weedon, SJ
Green, NK
McNeish, IA
Gilligan, MG
Mautner, V
Wrighton, CJ
Mountain, A
Young, LS
Kerr, DJ
Searle, PF
Citation: Sj. Weedon et al., Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirusvector-mediated expression of E-coli nitroreductase, INT J CANC, 86(6), 2000, pp. 848-854
Authors:
Latham, JPF
Searle, PF
Mautner, V
James, ND
Citation: Jpf. Latham et al., Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer: Construction and testing of a tissue-specific adenovirus vector, CANCER RES, 60(2), 2000, pp. 334-341
Citation: Pa. Gerin et al., Production of retroviral vectors for gene therapy with the human packagingcell line FLYRD18, BIOTECH PR, 15(5), 1999, pp. 941-948
Authors:
Gerin, PA
Gilligan, MG
Searle, PF
Al-Rubeai, M
Citation: Pa. Gerin et al., Improved titers of retroviral vectors from the human FLYRD18 packaging cell line in serum- and protein-free medium, HUM GENE TH, 10(12), 1999, pp. 1965-1974