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Results: 1-25 | 26-26
Results: 1-25/26
Adenovirus hexon protein enhances nuclear delivery and increases transgeneexpression of polyethylenimine/plasmid DNA vectors
Authors: Carlisle, RC Bettinger, T Ogris, M Hale, S Mautner, V Seymour, LW
Citation: Rc. Carlisle et al., Adenovirus hexon protein enhances nuclear delivery and increases transgeneexpression of polyethylenimine/plasmid DNA vectors, MOL THER, 4(5), 2001, pp. 473-483
Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo
Authors: Oupicky, D Carlisle, RC Seymour, LW
Citation: D. Oupicky et al., Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo, GENE THER, 8(9), 2001, pp. 713-724
Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies
Authors: Fisher, KD Stallwood, Y Green, NK Ulbrich, K Mautner, V Seymour, LW
Citation: Kd. Fisher et al., Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies, GENE THER, 8(5), 2001, pp. 341-348
Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetin
Authors: Mulholland, PJ Ferry, DR Anderson, D Hussain, SA Young, AM Cook, JE Hodgkin, E Seymour, LW Kerr, DJ
Citation: Pj. Mulholland et al., Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetin, ANN ONCOL, 12(2), 2001, pp. 245-248
Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells
Authors: Bettinger, T Carlisle, RC Read, ML Ogris, M Seymour, LW
Citation: T. Bettinger et al., Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells, NUCL ACID R, 29(18), 2001, pp. 3882-3891
Key issues in non-viral gene delivery
Authors: Pouton, CW Seymour, LW
Citation: Cw. Pouton et Lw. Seymour, Key issues in non-viral gene delivery, ADV DRUG DE, 46(1-3), 2001, pp. 187-203
Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells
Authors: Atkinson, SF Bettinger, T Seymour, LW Behr, JP Ward, CM
Citation: Sf. Atkinson et al., Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells, J BIOL CHEM, 276(30), 2001, pp. 27930-27935
Systemic circulation of poly(L-lysine)/DNA vectors is influenced by polycation molecular weight and type of DNA: differential circulation in mice andrats and the implications for human gene therapy
Authors: Ward, CM Read, ML Seymour, LW
Citation: Cm. Ward et al., Systemic circulation of poly(L-lysine)/DNA vectors is influenced by polycation molecular weight and type of DNA: differential circulation in mice andrats and the implications for human gene therapy, BLOOD, 97(8), 2001, pp. 2221-2229
Folic acid targeting of protein conjugates into ascites tumour cells from ovarian cancer patients
Authors: Ward, CM Acheson, N Seymour, LW
Citation: Cm. Ward et al., Folic acid targeting of protein conjugates into ascites tumour cells from ovarian cancer patients, J DRUG TAR, 8(2), 2000, pp. 119-123
Steric stabilization of poly-L-lysine/DNA complexes by the covalent attachment of semitelechelic poly [N-(2-hydroxypropyl)methacrylamide]
Authors: Oupicky, D Howard, KA Konak, C Dash, PR Ulbrich, K Seymour, LW
Citation: D. Oupicky et al., Steric stabilization of poly-L-lysine/DNA complexes by the covalent attachment of semitelechelic poly [N-(2-hydroxypropyl)methacrylamide], BIOCONJ CHE, 11(4), 2000, pp. 492-501
Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin
Authors: Pechar, M Ulbrich, K Subr, V Seymour, LW Schacht, EH
Citation: M. Pechar et al., Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin, BIOCONJ CHE, 11(2), 2000, pp. 131-139
A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression
Authors: Fisher, KD Ulbrich, K Subr, V Ward, CM Mautner, V Blakey, D Seymour, LW
Citation: Kd. Fisher et al., A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression, GENE THER, 7(15), 2000, pp. 1337-1343
Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers
Authors: Read, ML Dash, PR Clark, A Howard, KA Oupicky, D Toncheva, V Alpar, HO Schacht, EH Ulbrich, K Seymour, LW
Citation: Ml. Read et al., Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers, EUR J PH SC, 10(3), 2000, pp. 169-177
Influence of hydrophilicity of cationic polymers on the biophysical properties of polyelectrolyte complexes formed by self-assembly with DNA
Authors: Howard, KA Dash, PR Read, ML Ward, K Tomkins, LM Nazarova, O Ulbrich, K Seymour, LW
Citation: Ka. Howard et al., Influence of hydrophilicity of cationic polymers on the biophysical properties of polyelectrolyte complexes formed by self-assembly with DNA, BBA-GEN SUB, 1475(3), 2000, pp. 245-255
DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers
Authors: Oupicky, D Konak, C Ulbrich, K Wolfert, MA Seymour, LW
Citation: D. Oupicky et al., DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers, J CONTR REL, 65(1-2), 2000, pp. 149-171
Poly-L-glutamic acid derivatives as vectors for gene therapy
Authors: Dekie, L Toncheva, V Dubruel, P Schacht, EH Barrett, L Seymour, LW
Citation: L. Dekie et al., Poly-L-glutamic acid derivatives as vectors for gene therapy, J CONTR REL, 65(1-2), 2000, pp. 187-202
Decreased binding to proteins and cells of polymeric gene delivery vectorssurface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin
Authors: Dash, PR Read, ML Fisher, KD Howard, KA Wolfert, M Oupicky, D Subr, V Strohalm, J Ulbrich, K Seymour, LW
Citation: Pr. Dash et al., Decreased binding to proteins and cells of polymeric gene delivery vectorssurface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin, J BIOL CHEM, 275(6), 2000, pp. 3793-3802
High-performance liquid chromatographic method for sensitive determinationof the alkylating agent CB1954 in human plasma
Authors: Anderson, D Ferry, DR Knox, RJ Andrews, SJ Downes, AJ Kerr, DJ Seymour, LW
Citation: D. Anderson et al., High-performance liquid chromatographic method for sensitive determinationof the alkylating agent CB1954 in human plasma, J CHROMAT B, 731(2), 1999, pp. 293-298
Polyelectrolyte vectors for gene delivery: Influence of cationic polymer on biophysical properties of complexes formed with DNA
Authors: Wolfert, MA Dash, PR Nazarova, O Oupicky, D Seymour, LW Smart, S Strohalm, J Ulbrich, K
Citation: Ma. Wolfert et al., Polyelectrolyte vectors for gene delivery: Influence of cationic polymer on biophysical properties of complexes formed with DNA, BIOCONJ CHE, 10(6), 1999, pp. 993-1004
Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block
Authors: Oupicky, D Konak, C Dash, PR Seymour, LW Ulbrich, K
Citation: D. Oupicky et al., Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block, BIOCONJ CHE, 10(5), 1999, pp. 764-772
Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery
Authors: Dash, PR Read, ML Barrett, LB Wolfert, M Seymour, LW
Citation: Pr. Dash et al., Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery, GENE THER, 6(4), 1999, pp. 643-650
A sensitive assay system for the determination of poly(L-lysine) concentration using turbidometry
Authors: Ward, CM Fisher, KD Seymour, LW
Citation: Cm. Ward et al., A sensitive assay system for the determination of poly(L-lysine) concentration using turbidometry, J BIOACT C, 14(2), 1999, pp. 122-136
Targeted transfection of neuronal cells using a poly(D-lysine)-cholera-toxin b chain conjugate
Authors: Barrett, LB Logan, A Berry, M Ying, WB Gonzalez, AM Baird, A Seymour, LW
Citation: Lb. Barrett et al., Targeted transfection of neuronal cells using a poly(D-lysine)-cholera-toxin b chain conjugate, BIOCH SOC T, 27, 1999, pp. 851-857
Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine
Authors: Julyan, PJ Seymour, LW Ferry, DR Daryani, S Boivin, CM Doran, J David, M Anderson, D Christodoulou, C Young, AM Hesslewood, S Kerr, DJ
Citation: Pj. Julyan et al., Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine, J CONTR REL, 57(3), 1999, pp. 281-290
Macromolecular derivatives of N,N-di-(2-chloroethyl)-4-phenylene diamine mustard. 2. In vitro cytotoxicity and in vivo anticancer efficacy
Authors: Soyez, H Seymour, LW Schacht, E
Citation: H. Soyez et al., Macromolecular derivatives of N,N-di-(2-chloroethyl)-4-phenylene diamine mustard. 2. In vitro cytotoxicity and in vivo anticancer efficacy, J CONTR REL, 57(2), 1999, pp. 187-196
Risultati: 1-25 | 26-26