Authors:
Adelt, S
Plettenburg, O
Dallmann, G
Ritter, FP
Shears, SB
Altenbach, HJ
Vogel, G
Citation: S. Adelt et al., Regiospecific phosphohydrolases from Dictyostelium as tools for the chemoenzymatic synthesis of the enantiomers D-myo-inositol 1,2,4-trisphosphate and D-myo-inositol 2,3,6-trisphosphate: Non-physiological, potential analogues of biologically active D-myo-inositol 1,3,4-trisphosphate, BIOORG MED, 11(20), 2001, pp. 2705-2708
Authors:
Zhou, DG
Chen, LM
Hernandez, L
Shears, SB
Galan, JE
Citation: Dg. Zhou et al., A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host cell actin cytoskeleton rearrangements and bacterial internalization, MOL MICROB, 39(2), 2001, pp. 248-259
Citation: Jj. Caffrey et Sb. Shears, Genetic rationale for microheterogeneity of human diphosphoinositol polyphosphate phosphohydrolase type 2, GENE, 269(1-2), 2001, pp. 53-60
Citation: Cs. Liu et al., Synthesis and biological activity of D- and L-chiro-Inositol 2,3,4,5-tetrakisphosphate: Design of a novel and potent inhibitor of Ins(3,4,5,6)P-4 1-kinase/Ins(1,3,4)P-3 5/6-kinase, J MED CHEM, 44(18), 2001, pp. 2984-2989
Authors:
Ho, MWY
Kaetzel, MA
Armstrong, DL
Shears, SB
Citation: Mwy. Ho et al., Regulation of a human chloride channel - A paradigm for integrating input from calcium, type II calmodulin-dependent protein kinase, and inositol 3,4,5,6-tetrakisphosphate, J BIOL CHEM, 276(22), 2001, pp. 18673-18680
Authors:
Caffrey, JJ
Darden, T
Wenk, MR
Shears, SB
Citation: Jj. Caffrey et al., Expanding coincident signaling by PTEN through its inositol 1,3,4,5,6-pentakisphosphate 3-phosphatase activity, FEBS LETTER, 499(1-2), 2001, pp. 6-10
Citation: T. Zhang et al., The transcriptional regulator, Arg82, is a hybrid kinase with both monophosphoinositol and diphosphoinositol polyphosphate synthase activity, FEBS LETTER, 494(3), 2001, pp. 208-212
Citation: Hb. Chi et al., Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivo, MOL CELL B, 20(17), 2000, pp. 6496-6507
Citation: Xn. Yang et Sb. Shears, Multitasking in signal transduction by a promiscuous human Ins(3,4,5,6)P-41-kinase/Ins(1,3,4)P-3 5/6-kinase, BIOCHEM J, 351, 2000, pp. 551-555
Citation: Ma. Carew et al., myo-inositol 3,4,5,6-tetrakisphosphate inhibits an apical calcium-activated chloride conductance in polarized monolayers of a cystic fibrosis cell line, J BIOL CHEM, 275(35), 2000, pp. 26906-26913
Authors:
Saiardi, A
Caffrey, JJ
Snyder, SH
Shears, SB
Citation: A. Saiardi et al., The inositol hexakisphosphate kinase family - Catalytic flexibility and function in yeast vacuole biogenesis, J BIOL CHEM, 275(32), 2000, pp. 24686-24692
Authors:
Caffrey, JJ
Safrany, ST
Yang, XN
Shears, SB
Citation: Jj. Caffrey et al., Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases - An expanding Nudt family, J BIOL CHEM, 275(17), 2000, pp. 12730-12736
Citation: Mwy. Ho et al., Regulation of chloride channel conductance by Ins(3,4,5,6)P-4; a phosphoinositide-initiated signalling pathway that acts downstream of Ins(1,4,5)P-3, FR MOLEC B, 27, 2000, pp. 298-319
Authors:
Czirjak, G
Burkhart, WA
Moyer, MB
Antal, J
Shears, SB
Enyedi, P
Citation: G. Czirjak et al., Cloning and functional expression of the cytoplasmic form of rat aminopeptidase P, BBA-GENE ST, 1444(3), 1999, pp. 326-336
Citation: Xn. Yang et al., Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphatesand diphosphoinositol polyphosphates, J BIOL CHEM, 274(50), 1999, pp. 35434-35440
Authors:
Safrany, ST
Ingram, SW
Cartwright, JL
Falck, JR
McLennan, AG
Barnes, LD
Shears, SB
Citation: St. Safrany et al., The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase - Overlapping substrate specificities in a MutT-type protein, J BIOL CHEM, 274(31), 1999, pp. 21735-21740
Authors:
Yang, XN
Rudolf, M
Carew, RA
Yoshida, M
Nerreter, V
Riley, AM
Chung, SK
Bruzik, KS
Potter, BVL
Schultz, C
Shears, SB
Citation: Xn. Yang et al., Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate, J BIOL CHEM, 274(27), 1999, pp. 18973-18980
Authors:
Caffrey, JJ
Hidaka, K
Matsuda, M
Hirata, M
Shears, SB
Citation: Jj. Caffrey et al., The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification, FEBS LETTER, 442(1), 1999, pp. 99-104