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Results: 1-25 | 26-30
Results: 1-25/30
Hepatocyte nuclear factor-1 alpha is an essential regulator of bile acid and plasma cholesterol metabolism
Authors: Shih, DQ Bussen, M Sehayek, E Ananthanarayanan, M Shneider, BL Suchy, FJ Shefer, S Bollileni, JS Gonzalez, FJ Breslow, JL Stoffel, M
Citation: Dq. Shih et al., Hepatocyte nuclear factor-1 alpha is an essential regulator of bile acid and plasma cholesterol metabolism, NAT GENET, 27(4), 2001, pp. 375-382
Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis
Authors: Johnston, TP Nguyen, LB Chu, WA Shefer, S
Citation: Tp. Johnston et al., Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis, INT J PHARM, 229(1-2), 2001, pp. 75-86
Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance
Authors: VanPatten, S Ranginani, N Shefer, S Nguyen, LB Rossetti, L Cohen, DE
Citation: S. Vanpatten et al., Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance, AM J P-GAST, 281(2), 2001, pp. G393-G404
Plant stanol fatty acid esters inhibit cholesterol absorption and hepatic hydroxymethyl glutaryl coenzyme A reductase activity to reduce plasma levels in rabbits
Authors: Xu, GR Salen, G Shefer, S Tint, GS Nguyen, LB Batta, AK Pcolinsky, M
Citation: Gr. Xu et al., Plant stanol fatty acid esters inhibit cholesterol absorption and hepatic hydroxymethyl glutaryl coenzyme A reductase activity to reduce plasma levels in rabbits, METABOLISM, 50(9), 2001, pp. 1106-1112
Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: Effects of apolipoprotein E deficiency and probucol or phytosterol treatment
Authors: Moghadasian, MH Nguyen, LB Shefer, S Salen, G Batta, AK Frohlich, JJ
Citation: Mh. Moghadasian et al., Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: Effects of apolipoprotein E deficiency and probucol or phytosterol treatment, METABOLISM, 50(6), 2001, pp. 708-714
Macrophage 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: Effects of increased cellular cholesterol and sitosterol concentrations
Authors: Nguyen, LB Salen, G Shefer, S Tint, GS Ruiz, F
Citation: Lb. Nguyen et al., Macrophage 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: Effects of increased cellular cholesterol and sitosterol concentrations, METABOLISM, 50(10), 2001, pp. 1224-1229
Cholecystectomy prevents expansion of the bile acid pool and inhibition ofcholesterol 7 alpha-hydroxylase in rabbits fed cholesterol
Authors: Xu, GR Salen, G Shneider, BL Ananthanarayanan, M Shefer, S Ma, L Batta, A Nguyen, LB Lingutla, JJ Tint, GS Pcolinsky, M Suchy, FJ
Citation: Gr. Xu et al., Cholecystectomy prevents expansion of the bile acid pool and inhibition ofcholesterol 7 alpha-hydroxylase in rabbits fed cholesterol, J LIPID RES, 42(9), 2001, pp. 1438-1443
Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice
Authors: Sehayek, E Ono, JG Duncan, EM Batta, AK Salen, G Shefer, S Neguyen, LB Yang, K Lipkin, M Breslow, JL
Citation: E. Sehayek et al., Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice, J LIPID RES, 42(8), 2001, pp. 1250-1256
Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin
Authors: Nguyen, LB Shefer, S Salen, G Tint, GS Ruiz, F Bullock, J
Citation: Lb. Nguyen et al., Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin, J LIPID RES, 42(2), 2001, pp. 195-200
Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX
Authors: Honda, A Salen, G Matsuzaki, Y Batta, AK Xu, GR Leitersdorf, E Tint, GS Erickson, SK Tanaka, N Shefer, S
Citation: A. Honda et al., Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX, J LIPID RES, 42(2), 2001, pp. 291-300
7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppressessterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome
Authors: Fitzky, BU Moebius, FF Asaoka, H Waage-Baudet, H Xu, LW Xu, GR Maeda, N Kluckman, K Hiller, S Yu, HW Batta, AK Shefer, S Chen, T Salen, G Sulik, K Simoni, RD Ness, GC Glossmann, H Patel, SB Tint, GS
Citation: Bu. Fitzky et al., 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppressessterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome, J CLIN INV, 108(6), 2001, pp. 905-915
Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A aremarkedly up-regulated in Cyp27(-/-) mice but not in cerebrotendinous xanthomatosis
Authors: Honda, A Salen, G Matsuzaki, Y Batta, AK Xu, GR Leitersdorf, E Ting, GS Erickson, SK Tanaka, N Shefer, S
Citation: A. Honda et al., Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A aremarkedly up-regulated in Cyp27(-/-) mice but not in cerebrotendinous xanthomatosis, J BIOL CHEM, 276(37), 2001, pp. 34579-34585
Is there a relationship between 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and forebrain pathology in the PKU mouse?
Authors: Shefer, S Tint, GS Jean-Guillaume, D Daikhin, E Kendler, A Nguyen, LB Yudkoff, M Dyer, CA
Citation: S. Shefer et al., Is there a relationship between 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and forebrain pathology in the PKU mouse?, J NEUROSC R, 61(5), 2000, pp. 549-563
Regulation of cholesterol biosynthetic pathway in patients with the Smith-Lemli-Opitz syndrome
Authors: Honda, M Tint, GS Honda, A Salen, G Shefer, S Batta, AK Matsuzaki, Y Tanaka, N
Citation: M. Honda et al., Regulation of cholesterol biosynthetic pathway in patients with the Smith-Lemli-Opitz syndrome, J INH MET D, 23(5), 2000, pp. 464-474
Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: Studies in C57BL/6 apolipoprotein E knockout mice
Authors: Sehayek, E Shefer, S Nguyen, LB Ono, JG Merkel, M Breslow, JL
Citation: E. Sehayek et al., Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: Studies in C57BL/6 apolipoprotein E knockout mice, P NAS US, 97(7), 2000, pp. 3433-3437
Regulation of 25- and 27-hydroxylation side chain cleavage pathways for cholic acid biosynthesis in humans, rabbits, and mice: assay of enzyme activities by high-resolution gas chromatography-mass spectrometry
Authors: Honda, A Salen, G Shefer, S Matsuzaki, Y Xu, GR Batta, AK Tint, GS Tanaka, N
Citation: A. Honda et al., Regulation of 25- and 27-hydroxylation side chain cleavage pathways for cholic acid biosynthesis in humans, rabbits, and mice: assay of enzyme activities by high-resolution gas chromatography-mass spectrometry, J LIPID RES, 41(3), 2000, pp. 442-451
Ileal bile acid transport regulates bile acid pool, synthesis, and plasma cholesterol levels differently in cholesterol-fed rats and rabbits
Authors: Xu, GR Shneider, BL Shefer, S Nguyen, LB Batta, AK Tint, GS Arrese, M Thevananther, S Ma, L Stengelin, S Kramer, W Greenblatt, D Pcolinsky, M Salen, G
Citation: Gr. Xu et al., Ileal bile acid transport regulates bile acid pool, synthesis, and plasma cholesterol levels differently in cholesterol-fed rats and rabbits, J LIPID RES, 41(2), 2000, pp. 298-304
Hyperabsorption and retention of campestanol in a sitosterolemic homozygote: comparison with her mother and three control subjects
Authors: Salen, G Xu, GR Tint, GS Batta, AK Shefer, S
Citation: G. Salen et al., Hyperabsorption and retention of campestanol in a sitosterolemic homozygote: comparison with her mother and three control subjects, J LIPID RES, 41(11), 2000, pp. 1883-1889
3-hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts
Authors: Honda, A Salen, G Honda, M Batta, AK Tint, GS Xu, GR Chen, TS Tanaka, N Shefer, S
Citation: A. Honda et al., 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts, J LA CL MED, 135(2), 2000, pp. 174-179
Abnormal hepatic sinusoidal bile acid transport in an Amish kindred is notlinked to FIC1 and is improved by ursodiol
Authors: Morton, DH Salen, G Batta, AK Shefer, S Tint, GS Belchis, D Shneider, B Puffenberger, E Bull, L Knisely, AS
Citation: Dh. Morton et al., Abnormal hepatic sinusoidal bile acid transport in an Amish kindred is notlinked to FIC1 and is improved by ursodiol, GASTROENTY, 119(1), 2000, pp. 188-195
Thermodynamic prediction of active ingredient loading in polymeric microparticles
Authors: Tse, G Blankschtein, D Shefer, A Shefer, S
Citation: G. Tse et al., Thermodynamic prediction of active ingredient loading in polymeric microparticles, J CONTR REL, 60(1), 1999, pp. 77-100
Campestanol (24-methyl-5 alpha-cholestan-3 beta-ol) absorption and distribution in New Zealand white rabbits: Effect of dietary sitostanol
Authors: Xu, GR Salen, G Tint, GS Batta, AK Shefer, S
Citation: Gr. Xu et al., Campestanol (24-methyl-5 alpha-cholestan-3 beta-ol) absorption and distribution in New Zealand white rabbits: Effect of dietary sitostanol, METABOLISM, 48(3), 1999, pp. 363-368
Comparative regulation of hepatic sterol 27-hydroxylase and cholesterol 7 alpha-hydroxylase activities in the rat, guinea pig, and rabbit: Effects ofcholesterol and bile acids
Authors: Nguyen, LB Xu, GR Shefer, S Tint, GS Batta, A Salen, G
Citation: Lb. Nguyen et al., Comparative regulation of hepatic sterol 27-hydroxylase and cholesterol 7 alpha-hydroxylase activities in the rat, guinea pig, and rabbit: Effects ofcholesterol and bile acids, METABOLISM, 48(12), 1999, pp. 1542-1548
Histologic, hematologic, and biochemical characteristics of apo E-deficient mice: Effects of dietary cholesterol and phytosterols
Authors: Moghadasian, MH Nguyen, LB Shefer, S McManus, BM Frohlich, JJ
Citation: Mh. Moghadasian et al., Histologic, hematologic, and biochemical characteristics of apo E-deficient mice: Effects of dietary cholesterol and phytosterols, LAB INV, 79(3), 1999, pp. 355-364
Bile acid synthesis in the Smith-Lemli-Opitz syndrome: effects of dehydrocholesterols on cholesterol 7 alpha-hydroxylase and 27-hydroxylase activities in rat liver
Authors: Honda, A Salen, G Shefer, S Batta, AK Honda, M Xu, GR Tint, GS Matsuzaki, Y Shoda, J Tanaka, N
Citation: A. Honda et al., Bile acid synthesis in the Smith-Lemli-Opitz syndrome: effects of dehydrocholesterols on cholesterol 7 alpha-hydroxylase and 27-hydroxylase activities in rat liver, J LIPID RES, 40(8), 1999, pp. 1520-1528
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