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Results: 1-2 |
Results: 2
Discovery of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2 '- (methylsulfonyl)-[1,1 '-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa
Authors: Pinto, DJP Orwat, MJ Wang, SG Fevig, JM Quan, ML Amparo, E Cacciola, J Rossi, KA Alexander, RS Smallwood, AM Luettgen, JM Liang, L Aungst, BJ Wright, MR Knabb, RM Wong, PC Wexler, RR Lam, PYS
Citation: Djp. Pinto et al., Discovery of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2 '- (methylsulfonyl)-[1,1 '-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa, J MED CHEM, 44(4), 2001, pp. 566-578
Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors
Authors: Han, Q Dominguez, C Stouten, PFW Park, JM Duffy, DE Galemmo, RA Rossi, KA Alexander, RS Smallwood, AM Wong, PC Wright, MM Luettgen, JM Knabb, RM Wexler, RR
Citation: Q. Han et al., Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors, J MED CHEM, 43(23), 2000, pp. 4398-4415
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