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Results: 1-12 |
Results: 12
In vitro stimulation of warfarin metabolism by quinidine: Increases in theformation of 4 '- and 10-hydroxywarfarin
Authors: Ngui, JS Chen, Q Shou, MG Wang, RW Stearns, RA Baillie, TA Tang, W
Citation: Js. Ngui et al., In vitro stimulation of warfarin metabolism by quinidine: Increases in theformation of 4 '- and 10-hydroxywarfarin, DRUG META D, 29(6), 2001, pp. 877-886
Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans
Authors: Poon, GK Chen, Q Teffera, Y Ngui, JS Griffin, PR Braun, MP Doss, GA Freeden, C Stearns, RA Evans, DC Baillie, TA Tang, W
Citation: Gk. Poon et al., Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans, DRUG META D, 29(12), 2001, pp. 1608-1613
Discovery of an orally bioavailable alkyl oxadiazole beta(3) adrenergic receptor agonist
Authors: Feng, DQD Biftu, T Candelore, MR Cascieri, MA Colwell, LF Deng, LP Feeney, WP Forrest, MJ Hom, GJ MacIntyre, DE Miller, RR Stearns, RA Strader, CD Tota, L Wyvratt, MJ Fisher, MH Weber, AE
Citation: Dqd. Feng et al., Discovery of an orally bioavailable alkyl oxadiazole beta(3) adrenergic receptor agonist, BIOORG MED, 10(13), 2000, pp. 1427-1429
Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective beta(3) adrenergic receptor agonist antiobesity agents
Authors: Biftu, T Feng, DD Liang, GB Kuo, H Qian, XX Naylor, EM Colandrea, VJ Candelore, MR Cascieri, MA Colwell, LF Forrest, MJ Hom, GJ MacIntyre, DE Stearns, RA Strader, CD Wyvratt, MJ Fisher, MH Weber, AE
Citation: T. Biftu et al., Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective beta(3) adrenergic receptor agonist antiobesity agents, BIOORG MED, 10(13), 2000, pp. 1431-1434
Determination of brain and plasma drug concentrations by liquid chromatography/tandem mass spectrometry
Authors: Tamvakopoulos, CS Colwell, LF Barakat, K Fenyk-Melody, J Griffin, PR Nargund, R Palucki, B Sebhat, I Shen, X Stearns, RA
Citation: Cs. Tamvakopoulos et al., Determination of brain and plasma drug concentrations by liquid chromatography/tandem mass spectrometry, RAP C MASS, 14(19), 2000, pp. 1729-1735
Cytochrome P450 3A4-mediated interaction of diclofenac and quinidine
Authors: Ngui, JS Tang, W Stearns, RA Shou, MG Miller, RR Zhang, Y Lin, JH Baillie, TA
Citation: Js. Ngui et al., Cytochrome P450 3A4-mediated interaction of diclofenac and quinidine, DRUG META D, 28(9), 2000, pp. 1043-1050
Discovery of a potent, orally bioavailable beta(3) adrenergic receptor agonist, (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4-[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide
Authors: Mathvink, RJ Tolman, JS Chitty, D Candelore, MR Cascieri, MA Colwell, LF Deng, LP Feeney, WP Forrest, MJ Hom, GJ MacIntyre, DE Miller, RR Stearns, RA Tota, L Wyvratt, MJ Fisher, MH Weber, AE
Citation: Rj. Mathvink et al., Discovery of a potent, orally bioavailable beta(3) adrenergic receptor agonist, (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4-[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide, J MED CHEM, 43(21), 2000, pp. 3832-3836
L-770,644: A potent and selective human beta(3) adrenergic receptor agonist with improved oral bioavailability
Authors: Shih, TL Candelore, MR Cascieri, MA Chiu, SHL Colwell, LF Deng, LP Feeney, WP Forrest, MJ Hom, GJ MacIntyre, DE Miller, RR Stearns, RA Strader, CD Tota, L Wyvratt, MJ Fisher, MH Weber, AE
Citation: Tl. Shih et al., L-770,644: A potent and selective human beta(3) adrenergic receptor agonist with improved oral bioavailability, BIOORG MED, 9(9), 1999, pp. 1251-1254
Human beta(3) adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides
Authors: Parmee, ER Naylor, EM Perkins, L Colandrea, VJ Ok, HO Candelore, MR Cascieri, MA Deng, LP Feeney, WP Forrest, MJ Hom, GJ MacIntyre, DE Miller, RR Stearns, RA Strader, CD Tota, L Wyvratt, MJ Fisher, MH Weber, AE
Citation: Er. Parmee et al., Human beta(3) adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides, BIOORG MED, 9(5), 1999, pp. 749-754
Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac
Authors: Tang, W Stearns, RA Wang, RW Chiu, SHL Baillie, TA
Citation: W. Tang et al., Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac, CHEM RES T, 12(2), 1999, pp. 192-199
Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: Identification of glutathione conjugated metabolites
Authors: Tang, W Stearns, RA Bandiera, SM Zhang, Y Raab, C Braun, MP Dean, DC Pang, JM Leung, KH Doss, GA Strauss, JR Kwei, GY Rushmore, TH Chiu, SHL Baillie, TA
Citation: W. Tang et al., Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: Identification of glutathione conjugated metabolites, DRUG META D, 27(3), 1999, pp. 365-372
Interaction of diclofenac and quinidine in monkeys: Stimulation of diclofenac metabolism
Authors: Tang, W Stearns, RA Kwei, GY Iliff, SA Miller, RR Egan, MA Yu, NX Dean, DC Kumar, S Shou, MG Lin, JH Baillie, TA
Citation: W. Tang et al., Interaction of diclofenac and quinidine in monkeys: Stimulation of diclofenac metabolism, J PHARM EXP, 291(3), 1999, pp. 1068-1074
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