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Results:
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Results: 20
Authors:
Steinkuhler, C
Koch, U
Narjes, F
Matassa, VG
Citation: C. Steinkuhler et al., Hepatitis C virus serine protease inhibitors: Current progress and future challenges, CURR MED CH, 8(8), 2001, pp. 919-932
Authors:
Pallaoro, M
Lahm, A
Biasiol, G
Brunetti, M
Nardella, C
Orsatti, L
Bonelli, F
Orru, S
Narjes, F
Steinkuhler, C
Citation: M. Pallaoro et al., Characterization of the hepatitis C virus NS2/3 processing reaction by using a purified precursor protein, J VIROLOGY, 75(20), 2001, pp. 9939-9946
Authors:
Koch, U
Biasiol, G
Brunetti, M
Fattori, D
Pallaoro, M
Steinkuhler, C
Citation: U. Koch et al., Role of charged residues in the catalytic mechanism of hepatitis C virus NS3 protease: Electrostatic precollision guidance and transition-state stabilization, BIOCHEM, 40(3), 2001, pp. 631-640
Authors:
De Francesco, R
Neddermann, P
Tomei, L
Steinkuhler, C
Gallinari, P
Folgori, A
Citation: R. De Francesco et al., Biochemical and immunologic properties of the nonstructural proteins of the hepatitis C virus: Implications for development of antiviral agents and vaccines, SEM LIV DIS, 20(1), 2000, pp. 69-83
Authors:
De Francesco, R
Steinkuhler, C
Citation: R. De Francesco et C. Steinkuhler, Structure and function of the hepatitis C virus NS3-NS4A serine proteinase, CURR T MICR, 242, 2000, pp. 149-169
Authors:
Pacini, L
Vitelli, A
Filocamo, G
Bartholomew, L
Brunetti, M
Tramontano, A
Steinkuhler, C
Migliaccio, G
Citation: L. Pacini et al., In vivo selection of protease cleavage sites by using chimeric Sindbis virus libraries, J VIROLOGY, 74(22), 2000, pp. 10563-10570
Authors:
Fattori, D
Urbani, A
Brunetti, M
Ingenito, R
Pessi, A
Prendergast, K
Narjes, F
Matassa, VG
De Francesco, R
Steinkuhler, C
Citation: D. Fattori et al., Probing the active site of the hepatitis C virus serine protease by fluorescence resonance energy transfer, J BIOL CHEM, 275(20), 2000, pp. 15106-15113
Authors:
Narjes, F
Brunetti, M
Colarusso, S
Gerlach, B
Koch, U
Biasiol, G
Fattori, D
De Francesco, R
Matassa, VG
Steinkuhler, C
Citation: F. Narjes et al., alpha-ketoacids are potent slow binding inhibitors of the hepatitis C virus NS3 protease, BIOCHEM, 39(7), 2000, pp. 1849-1861
Authors:
Ingallinella, P
Bianchi, E
Ingenito, R
Koch, U
Steinkuhler, C
Altamura, S
Pessi, A
Citation: P. Ingallinella et al., Optimization of the P '-region of peptide inhibitors of hepatitis C virus NS3/4A protease, BIOCHEM, 39(42), 2000, pp. 12898-12906
Authors:
De Francesco, R
Pessi, A
Steinkuhler, C
Citation: R. De Francesco et al., Mechanisms of hepatitis C virus NS3 proteinase inhibitors, J VIRAL HEP, 6, 1999, pp. 23-30
Authors:
Orru, S
Dal Piaz, F
Casbarra, A
Biasiol, G
De Francesco, R
Steinkuhler, C
Pucci, P
Citation: S. Orru et al., Conformational changes in the NS3 protease from hepatitis C virus strain Bk monitored by limited proteolysis and mass spectrometry, PROTEIN SCI, 8(7), 1999, pp. 1445-1454
Authors:
Martin, F
Steinkuhler, C
Brunetti, M
Pessi, A
Cortese, R
De Francesco, R
Sollazzo, M
Citation: F. Martin et al., A loop-mimetic inhibitor of the HCV-NS3 protease derived from a minibody, PROTEIN ENG, 12(11), 1999, pp. 1005-1011
Authors:
Barbato, G
Cicero, DO
Nardi, MC
Steinkuhler, C
Cortese, R
De Francesco, R
Bazzo, R
Citation: G. Barbato et al., The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism, J MOL BIOL, 289(2), 1999, pp. 371-384
Authors:
Cicero, DO
Barbato, G
Koch, U
Ingallinella, P
Bianchi, E
Nardi, MC
Steinkuhler, C
Cortese, R
Matassa, V
De Francesco, R
Pessi, A
Bazzo, R
Citation: Do. Cicero et al., Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies, J MOL BIOL, 289(2), 1999, pp. 385-396
Authors:
Gallinari, P
Paolini, C
Brennan, D
Nardi, C
Steinkuhler, C
De Francesco, R
Citation: P. Gallinari et al., Modulation of hepatitis C virus NS3 protease and helicase activities through the interaction with NS4A, BIOCHEM, 38(17), 1999, pp. 5620-5632
Authors:
Urbani, A
Biasiol, G
Brunetti, M
Volpari, C
Di Marco, S
Sollazzo, M
Orru, S
Dal Piaz, F
Casbarra, A
Pucci, P
Nardi, C
Gallinari, P
De Francesco, R
Steinkuhler, C
Citation: A. Urbani et al., Multiple determinants influence complex formation of the hepatitis C virusNS3 protease domain with ils NS4A cofactor peptide, BIOCHEM, 38(16), 1999, pp. 5206-5215
Authors:
Cerretani, N
Di Renzo, L
Serafini, S
Vitelli, A
Gennari, N
Bianchi, E
Pessi, A
Urbani, A
Colloca, S
De Francesco, R
Steinkuhler, C
Altamura, S
Citation: N. Cerretani et al., A high-throughput radiometric assay for hepatitis C virus NS3 protease, ANALYT BIOC, 266(2), 1999, pp. 192-197
Authors:
Pasquo, A
Nardi, MC
Dimasi, N
Tomei, L
Steinkuhler, C
Delmastro, P
Tramontano, A
De Francesco, R
Citation: A. Pasquo et al., Rational design and functional expression of a constitutively active single-chain NS4A-NS3 proteinase, FOLD DES, 3(6), 1998, pp. 433-441
Authors:
Dimasi, N
Pasquo, A
Martin, F
Di Marco, S
Steinkuhler, C
Cortese, R
Sollazzo, M
Citation: N. Dimasi et al., Engineering, characterization and phage display of hepatitis C virus NS3 protease and NS4A cofactor peptide as a single-chain protein, PROTEIN ENG, 11(12), 1998, pp. 1257-1265
Authors:
De Francesco, R
Pessi, A
Steinkuhler, C
Citation: R. De Francesco et al., The hepatitis C virus NS3 proteinase: structure and function of a zinc-containing serine proteinase, THERAPIES FOR VIRAL HEPATITIS, 1998, pp. 235-245
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