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Results: 1-13 |
Results: 13
HIGH-THROUGHPUT APPROACHES FOR EVALUATING ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION PROPERTIES OF LEAD COMPOUNDS
Authors: TARBIT MH BERMAN J
Citation: Mh. Tarbit et J. Berman, HIGH-THROUGHPUT APPROACHES FOR EVALUATING ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION PROPERTIES OF LEAD COMPOUNDS, Current opinion in chemical biology, 2(3), 1998, pp. 411-416
MOLECULAR MODELING OF HUMAN CYP2C SUBFAMILY ENZYMES CYP2C9 AND CYP2C19 - RATIONALIZATION OF SUBSTRATE-SPECIFICITY AND SITE-DIRECTED MUTAGENESIS EXPERIMENTS IN THE CYP2C SUBFAMILY
Authors: LEWIS DFV DICKINS M WEAVER RJ EDDERSHAW PJ GOLDFARB PS TARBIT MH
Citation: Dfv. Lewis et al., MOLECULAR MODELING OF HUMAN CYP2C SUBFAMILY ENZYMES CYP2C9 AND CYP2C19 - RATIONALIZATION OF SUBSTRATE-SPECIFICITY AND SITE-DIRECTED MUTAGENESIS EXPERIMENTS IN THE CYP2C SUBFAMILY, Xenobiotica, 28(3), 1998, pp. 235-268
STRUCTURAL DETERMINANTS OF CYTOCHROME-P450 SUBSTRATE-SPECIFICITY, BINDING-AFFINITY AND CATALYTIC RATE
Authors: LEWIS DFV EDDERSHAW PJ DICKENS M TARBIT MH GOLDFARB PS
Citation: Dfv. Lewis et al., STRUCTURAL DETERMINANTS OF CYTOCHROME-P450 SUBSTRATE-SPECIFICITY, BINDING-AFFINITY AND CATALYTIC RATE, Chemico-biological interactions, 115(3), 1998, pp. 175-199
MOLECULAR MODELING OF CYTOCHROME P4502D6 (CYP2D6) BASED ON AN ALIGNMENT WITH CYP102 - STRUCTURAL STUDIES ON SPECIFIC CYP2D6 SUBSTRATE METABOLISM
Authors: LEWIS DFV EDDERSHAW PJ GOLDFARB PS TARBIT MH
Citation: Dfv. Lewis et al., MOLECULAR MODELING OF CYTOCHROME P4502D6 (CYP2D6) BASED ON AN ALIGNMENT WITH CYP102 - STRUCTURAL STUDIES ON SPECIFIC CYP2D6 SUBSTRATE METABOLISM, Xenobiotica, 27(4), 1997, pp. 319-339
GENETIC-ANALYSIS OF THE HUMAN CYTOCHROME-P450 CYP2C9 LOCUS
Authors: STUBBINS MJ HARRIES LW SMITH G TARBIT MH WOLF CR
Citation: Mj. Stubbins et al., GENETIC-ANALYSIS OF THE HUMAN CYTOCHROME-P450 CYP2C9 LOCUS, Pharmacogenetics, 6(5), 1996, pp. 429-439
THE ALIPHATIC OXIDATION OF SALMETEROL TO ALPHA-HYDROXYSALMETEROL IN HUMAN LIVER-MICROSOMES IS CATALYZED BY CYP3A
Authors: MANCHEE GR EDDERSHAW PJ RANSHAW LE HERRIOTT D PARK GR BAYLISS MK TARBIT MH
Citation: Gr. Manchee et al., THE ALIPHATIC OXIDATION OF SALMETEROL TO ALPHA-HYDROXYSALMETEROL IN HUMAN LIVER-MICROSOMES IS CATALYZED BY CYP3A, Drug metabolism and disposition, 24(5), 1996, pp. 555-559
MOLECULAR MODELING OF CYP3A4 FROM AN ALIGNMENT WITH CYP102 - IDENTIFICATION OF KEY INTERACTIONS BETWEEN PUTATIVE ACTIVE-SITE RESIDUES AND CYP3A-SPECIFIC CHEMICALS
Authors: LEWIS DFV EDDERSHAW PJ GOLDFARB PS TARBIT MH
Citation: Dfv. Lewis et al., MOLECULAR MODELING OF CYP3A4 FROM AN ALIGNMENT WITH CYP102 - IDENTIFICATION OF KEY INTERACTIONS BETWEEN PUTATIVE ACTIVE-SITE RESIDUES AND CYP3A-SPECIFIC CHEMICALS, Xenobiotica, 26(10), 1996, pp. 1067-1086
MULTIPLE FORMS OF CYTOCHROME-P450 ARE INVOLVED IN THE METABOLISM OF ONDANSETRON IN HUMANS
Authors: DIXON CM COLTHUP PV SERABJITSINGH CJ KERR BM BOEHLERT CC PARK GR TARBIT MH
Citation: Cm. Dixon et al., MULTIPLE FORMS OF CYTOCHROME-P450 ARE INVOLVED IN THE METABOLISM OF ONDANSETRON IN HUMANS, Drug metabolism and disposition, 23(11), 1995, pp. 1225-1230
DISPOSITION OF AZOLE ANTIFUNGAL AGENTS .2. HEPATIC BINDING AND CLEARANCE OF DICHLOROPHENYL-BIS-TRIAZOLYLPROPANOL (DTP) IN THE RAT
Authors: BOMONT HL TARBIT MH HUMPHREY MJ HOUSTON JB
Citation: Hl. Bomont et al., DISPOSITION OF AZOLE ANTIFUNGAL AGENTS .2. HEPATIC BINDING AND CLEARANCE OF DICHLOROPHENYL-BIS-TRIAZOLYLPROPANOL (DTP) IN THE RAT, Pharmaceutical research, 11(7), 1994, pp. 951-960
CHARACTERIZATION OF THE ENZYME RESPONSIBLE FOR THE METABOLISM OF SUMATRIPTAN IN HUMAN LIVER
Authors: DIXON CM PARK GR TARBIT MH
Citation: Cm. Dixon et al., CHARACTERIZATION OF THE ENZYME RESPONSIBLE FOR THE METABOLISM OF SUMATRIPTAN IN HUMAN LIVER, Biochemical pharmacology, 47(7), 1994, pp. 1253-1257
APPLICATIONS OF MOLECULAR-BIOLOGY AND IN-VITRO TECHNOLOGY TO DRUG-METABOLISM STUDIES - AN INDUSTRIAL PERSPECTIVE
Authors: TARBIT MH BAYLISS MK HERRIOTT D HOOD SR HUTSON JL PARK GR SERABJITSINGH CJ
Citation: Mh. Tarbit et al., APPLICATIONS OF MOLECULAR-BIOLOGY AND IN-VITRO TECHNOLOGY TO DRUG-METABOLISM STUDIES - AN INDUSTRIAL PERSPECTIVE, Biochemical Society transactions, 21(4), 1993, pp. 1018-1023
DISPOSITION OF SALMETEROL XINAFOATE IN LABORATORY-ANIMALS AND HUMANS
Authors: MANCHEE GR BARROW A KULKARNI S PALMER E OXFORD J COLTHUP PV MACONOCHIE JG TARBIT MH
Citation: Gr. Manchee et al., DISPOSITION OF SALMETEROL XINAFOATE IN LABORATORY-ANIMALS AND HUMANS, Drug metabolism and disposition, 21(6), 1993, pp. 1022-1028
DISPOSITION OF SUMATRIPTAN IN LABORATORY-ANIMALS AND HUMANS
Authors: DIXON CM SAYNOR DA ANDREW PD OXFORD J BRADBURY A TARBIT MH
Citation: Cm. Dixon et al., DISPOSITION OF SUMATRIPTAN IN LABORATORY-ANIMALS AND HUMANS, Drug metabolism and disposition, 21(5), 1993, pp. 761-769
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